DNA Synthesis Market Research Report Information By Service (Oligonucleotide Synthesis, Custom Oligonucleotide Synthesis, Pre-designed Oligonucleotide Synthesis, Gene Synthesis), By Application (Research and Development, Therapeutics, Diagnostic), By End-User (Biopharmaceutical Companies, Academic and Research Institutes, Contract Research Organizations) And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2034

Global DNA synthesis Market Overview

As per MRFR analysis, the DNA synthesis Market Size was estimated at 3.63 (USD Billion) in 2024. The DNA synthesis Market Industry is expected to grow from 4.37 (USD Billion) in 2025 to 23.42 (USD Billion) till 2034, at a CAGR (growth rate) is expected to be around 20.50% during the forecast period (2025 - 2034). DNA synthesis assists in the development of life-saving drugs and the development of gene the therapies are the key market drivers enhancing the market growth.

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

DNA Synthesis Market Trends

• Increasing demand for customized DNA sequences is driving the market growth

One prominent trend in the DNA synthesis market is the growing demand for customized DNA sequences. With advancements in synthetic biology and genetic engineering, researchers and biotech companies are increasingly seeking tailor-made DNA constructs for various applications such as gene editing, gene therapy, and synthetic biology. Customized DNA synthesis services enable researchers to design and order specific DNA sequences with precise nucleotide sequences and modifications, facilitating experimentation and innovation in molecular biology and biotechnology. This factor drives the market CAGR.

Additionally, another key trend shaping the DNA synthesis market is the adoption of automation and high-throughput synthesis platforms. As the demand for synthetic DNA continues to rise, there is a need for efficient and scalable synthesis technologies that can produce large quantities of DNA quickly and accurately. Automated DNA synthesis platforms, coupled with robotics and advanced chemistry, enable high-throughput production of DNA oligonucleotides and gene constructs, reducing turnaround times and costs for researchers and biotech companies. These automated systems also enhance reproducibility and quality control in DNA synthesis workflows.

The DNA synthesis market is witnessing the emergence of next-generation synthesis technologies aimed at overcoming the limitations of traditional DNA synthesis methods. Innovations such as enzymatic DNA synthesis, microfluidic-based synthesis, and DNA laser printing are revolutionizing the field by offering faster, cheaper, and more efficient ways to generate synthetic DNA. These novel technologies enable precise control over DNA sequence assembly, synthesis speed, and scalability, opening up new possibilities for applications in areas such as precision medicine, synthetic biology, and DNA data storage. The adoption of next-generation DNA synthesis technologies is expected to drive further advancements and growth in the DNA synthesis market. For instance, June 2023: Erasca, Inc., a clinical-stage precision oncology company, received the United States Food and Drug Administration (FDA) Orphan Drug Designation (ODD) to ERAS-801 for the treatment of malignant glioma, which includes glioblastoma (GBM). ERAS-801 is an orally bioavailable, small-molecule EGFR inhibitor that exhibited substantial central nervous system (CNS) penetration in preclinical animal studies. Thus, driving the DNA synthesis market revenue.

DNA synthesis Market Segment Insights

DNA synthesis Service Insights

The DNA synthesis Market segmentation, based on Service includes Oligonucleotide Synthesis, Custom Oligonucleotide Synthesis, Pre-designed Oligonucleotide Synthesis, Gene Synthesis. The dominant category is Custom Oligonucleotide Synthesis, primarily due to the increasing demand for tailor-made DNA sequences in research, biotechnology, and medical applications. Custom Oligonucleotide synthesis services allow researchers to specify the desired DNA sequence, modifications, and scale, enabling precise customization for specific experimental or therapeutic purposes. Meanwhile, the fastest-growing category is Gene Synthesis, driven by advancements in synthetic biology, gene editing, and gene therapy.

DNA synthesis Application Insights

The DNA synthesis Market segmentation, based on Application, includes Research and Development, Therapeutics, Diagnostic. The dominant category is Research and Development, primarily due to the extensive use of synthetic DNA sequences in molecular biology research, genetic engineering, and synthetic biology projects. Meanwhile, the fastest-growing category is Therapeutics, driven by the rising interest in gene therapy, nucleic acid-based therapeutics, and personalized medicine. DNA synthesis plays a crucial role in the development of therapeutic interventions, including gene editing technologies like CRISPR-Cas9, RNA interference (RNAi) therapies, and mRNA-based vaccines.

Figure 1: DNA synthesis market, by Application, 2023 & 2032 (USD Billion)

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

DNA Synthesis End-User Insights

The DNA synthesis Market segmentation, based on End-User, includes Biopharmaceutical Companies, Academic and Research Institutes, Contract Research Organizations. The dominant category is biopharmaceutical companies, primarily due to their significant investment in drug discovery, development, and biotechnology research. Meanwhile, the fastest-growing category is Academic and Research Institutes, fueled by the growing emphasis on genomic research, molecular biology, and synthetic biology in academic settings.

DNA Synthesis Regional Insights

By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The North American DNA synthesis market area will dominate this market, owing to robust biotechnology and pharmaceutical industry, with numerous biopharmaceutical companies, research institutes, and academic institutions driving demand for DNA synthesis services. In addition, the growing number of establishing health clubs and fitness facilities will boost market growth in this region.

Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

Figure2: DNA SYNTHESIS MARKET SHARE BY REGION 2023 (USD Billion)

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

Europe DNA synthesis market accounts for the second-largest market share due to strong presence of biopharmaceutical companies, academic institutions, and research organizations actively engaged in genomic research, drug discovery, and molecular biology studies. Further, the German DNA synthesis market held the largest market share, and the UK DNA synthesis market was the fastest growing market in the European region

The Asia-Pacific DNA synthesis Market is expected to grow at the fastest CAGR from 2024 to 2032. This is due to the growing demand for DNA synthesis services to support research and development activities, drug discovery efforts, and personalized medicine initiatives across Asia-Pacific.Moreover, China’s DNA synthesis market held the largest market share, and the Indian DNA synthesis market was the fastest growing market in the Asia-Pacific region.

DNA Synthesis Key Market Players& Competitive Insights

Leading market players are investing heavily in research and development in order to expand their product lines, which will help the DNA synthesis market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their global footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, DNA synthesisindustry must offer cost-effective items.

Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the DNA synthesis market industry to benefit clients and increase the market sector. In recent years, the DNA synthesisindustry has offered some of the most significant advantages. Major players in the DNA synthesis market, including GC Biosearch Technologie, Bioneer Corporation, Thermo Fisher Scientific, Inc., IBA GmbH, Twist Bioscience, Eton Bioscience, Quintara Biosciences, Eurofins Scientific, Integrated DNA Technologies, Inc., GenScript Biotech Corporation and others, are attempting to increase market demand by investing in research and development operations.

BIONEER Corporation is a biotechnology company headquartered in Daejeon, South Korea. Established in 1992, BIONEER specializes in the development and commercialization of innovative molecular biology tools and solutions. In February 2021, the "AccuLoaderTM," a novel concept auxiliary device introduced by BIONEER Corporation, is intended to speed up sample preparation by helping to dispense samples and reagents into the proper wells.

LGC Genomics is a division of LGC Group, a global life sciences company headquartered in Teddington, United Kingdom. LGC Genomics specializes in providing genomics products and services to support research, diagnostics, and applied markets. The company offers a comprehensive range of solutions, including nucleic acid extraction kits, genotyping and sequencing services, and custom assay development. In November 2018, the genomics business of LGC announced that it is rebranding as LGC, Biosearch Technologies, a portfolio brand that integrates optimized genetic analysis tools and technology to speed up scientific results.

Key Companies in the DNA synthesis market include

• LGC Biosearch Technologie


• Bioneer Corporation


• Thermo Fisher Scientific Inc.


• IBA GmbH


• Twist Bioscience


• Eton Bioscience


• Quintara Biosciences


• Eurofins Scientific


• Integrated DNA Technologies, Inc.


• GenScript Biotech Corporation

DNA Synthesis Industry Developments

March 2021: Aldevron expanded its manufacturing facility at Madison. At this new facility, the company is scaling up the manufacturing of gene synthesis products and ground-breaking therapies, among others.

February 2018: Twist Bioscience expanded its presence in North America by opening a new office in San Diego, California. The company has adopted this initiative to scale up the manufacturing of synthetic gene constructs and DNA constructs.

Molecular Assemblies, Inc. launched a Partnering Program in May 2024 to grant licenses for the company's Full Enzymatic Synthesis. For this effort, selected participants will receive the company's automation synthesis platform, all advancements or changes made to the FES platform, and the necessary permits to perform FES research in their facilities

In November 2023, the division of LGC Limited called LGC Biosearch Technologies purchased PolyDesign, which is a supplier and manufacturer of solid supports embedded frits for low and ultra-low-scale synthesis and purification of DNA and RNA oligonucleotides, to increase the company's capabilities in oligonucleotide products.

GenScript, in May 2023, reported the construction of new facilities to increase the production of oligonucleotides and peptides at their site in Zhenjiang, China. The purpose of such expansion is to meet the increasing orders for oligonucleotide and peptide synthesis that are needed for molecular diagnostics and vaccine development. This seeks and proactive approaches from these key players to strengthen their position within the global market for oligonucleotide synthesis foster the advancement of the segment in the region

In April 2024, Pfizer Inc. released news regarding the approval from the U.S. Food and Drug Administration (FDA) on BEQVEZ, the adeno-associated virus (AAV) gene therapy for arms deep to moderate and severe hemophilia B in adults

DNA Synthesis Market Segmentation

DNA Synthesis Service Outlook

• Oligonucleotide Synthesis


• Custom Oligonucleotide Synthesis


• Pre-designed Oligonucleotide Synthesis


• Gene Synthesis

DNA Synthesis Application Outlook

• Research and Development


• Therapeutics


• Diagnostic

DNA Synthesis End-User Outlook

• Biopharmaceutical Companies


• Academic and Research Institutes


• Contract Research Organizations

DNA Synthesis Regional Outlook

• North America
  
  
  
  • US
  
  
  • Canada
  
  
  
  


• Europe
  
  
  
  • Germany
  
  
  • France
  
  
  • UK
  
  
  • Italy
  
  
  • Spain
  
  
  • Rest of Europe
  
  
  
  


• Asia-Pacific
  
  
  
  • China
  
  
  • Japan
  
  
  • India
  
  
  • Australia
  
  
  • South Korea
  
  
  • Australia
  
  
  • Rest of Asia-Pacific
  
  
  
  


• Rest of the World
  
  
  
  • Middle East
  
  
  • Africa
  
  
  • Latin America
  
  
  
  

Report Attribute/Metric	Details
Market Size 2024	3.63 (USD Billion)
Market Size 2025	4.37 (USD Billion)
Market Size 2034	23.42 (USD Billion)
Compound Annual Growth Rate (CAGR)	20.50 % (2025 - 2034)
Report Coverage	Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year	2024
Market Forecast Period	2025 - 2034
Historical Data	2020 - 2024
Report Coverage	Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
Segments Covered	Service, Application, End-User and Region
Geographies Covered	North America, Europe, AsiaPacific, and the Rest of the World
Countries Covered	The US, Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
Key Companies Profiled	GC Biosearch Technologie, Bioneer Corporation, Thermo Fisher Scientific, Inc., IBA GmbH, Twist Bioscience, Eton Bioscience, Quintara Biosciences, Eurofins Scientific, Integrated DNA Technologies, Inc., GenScript Biotech Corporation
Key Market Opportunities	·       DNA synthesis assists in the development of life-saving drugs
Key Market Dynamics	·       The development of gene therapies