DNA Synthesis Market Overview
As per MRFR analysis, the DNA Synthesis Market Size was estimated at 4.24 (USD Billion) in 2023. The DNA Synthesis Market Industry is expected to grow from 4.63(USD Billion) in 2024 to 12 (USD Billion) by 2035. The DNA Synthesis Market CAGR (growth rate) is expected to be around 9.05% during the forecast period (2025 - 2035).
Key DNA Synthesis Market Trends Highlighted
The Global DNA Synthesis Market is witnessing significant trends driven largely by advancements in biotechnology and genetic research. Key market drivers include the increasing demand for synthetic DNA in various applications such as drug development, gene therapy, and agricultural biotechnology. The rise of personalized medicine is also a critical factor, as healthcare increasingly seeks tailored therapies based on individual genetic profiles. Governments globally are promoting research and development in genetics, creating conducive environments for the expansion of this market.
Opportunities to be explored include the potential for customized DNA solutions that can cater to specific client needs, which is gaining traction within academic and commercial research settings. The application of synthetic biology to the development of biofuels, new medicines, and even biodegradable plastics highlights synthetic biology's innovation potential. In developing nations, there is a growing utilization of genetic technologies, marking an opportunity for investment.
Recently, there seems to be an increase in partnerships between biotechnological enterprises and academic institutions, which is beneficial for research purposes. Moreover, the ongoing automation of DNA synthesis makes the process more economical, efficient, and widely adopted in laboratories and commercial settings. Moreover, advancements in CRISPR technology are expanding DNA synthesis capabilities facilitating new research pathways and applications. Overall, the Global DNA Synthesis Market is positioned for growth as it continues to evolve in response to scientific advancements and societal needs.
Source: Primary Research, Secondary Research, MRFR Database and Analyst Review
DNA Synthesis Market Drivers
Increasing Demand for Personalized Medicine
The rising trend towards personalized medicine is significantly driving the Global DNA Synthesis Market Industry. As healthcare increasingly emphasizes tailoring treatments to the individual patient's genetic makeup, the demand for synthesized DNA for Research and Development purposes is growing. According to data from the National Institutes of Health, over 20 million people in the United States are involved in personalized medicine initiatives as of 2023.
This has resulted in an expansion of genetic testing services and an increased focus on developing targeted therapies. With leading organizations such as the American Society of Clinical Oncology advocating for precision medicine approaches, the urgency to develop unique DNA sequences to adapt therapies is prompting a surge in the market as more healthcare providers adopt this model to improve patient outcomes.
Advancement in Synthetic Biology
The rapid advancements in synthetic biology are paving the way for the growth of the Global DNA Synthesis Market Industry. Recent technological breakthroughs, including CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology, have made DNA synthesis more accessible and efficient. The U.S. Department of Energy reports that the synthetic biology market is expected to reach a valuation of USD 20 billion by 2025, highlighting the escalated interest in creating new biological systems.
Organizations like the Synthetic Biology Leadership Council are driving innovation and investment, ultimately leading to increased applications of DNA synthesis in agriculture, energy, and pharmaceuticals, which in turn propels the DNA synthesis sector.
Growing Applications in Gene Therapy
The increasing applications of DNA synthesis in gene therapy are majorly contributing to the growth of the Global DNA Synthesis Market Industry. With nearly 22 gene therapies gaining approval from the Food and Drug Administration from 2015 to 2022, there has been a marked increase in the need for precise DNA constructs. The World Health Organization estimates that genetic diseases affect around 7% of the global population, indicating a vast potential market for gene therapies that rely on DNA synthesis.
Establishments like the European Society of Gene and Cell Therapy are actively promoting research in this domain, leading to heightened investment and innovation in the synthetic DNA field.
Rising Investment in Biotechnology and Pharmaceutical Research
An increase in investments targeted at the biotechnology and pharmaceutical research sectors is significantly driving the Global DNA Synthesis Market Industry. A report from the Biotechnology Innovation Organization indicates that venture capital investments in biotechnology firms reached a new high of USD 23 billion in 2022.
This rise in funding supports extensive Research and Development activities that rely on synthesized DNA for drug development and genetic research. Notable biotech firms, including Amgen and Genentech, are ramping up their R&D efforts, leading to a growing requirement for high-quality synthetic DNA across the industry, thereby directly influencing market expansion.
DNA Synthesis Market Segment Insights
DNA Synthesis Market Application Insights
The Global DNA Synthesis Market, particularly in the Application segment, demonstrates substantial growth, with strong revenue figures projected for the coming years. In 2024, this segment contributed to an overall market valuation of 4.63 USD Billion, with various segments reflecting diverse applications of DNA synthesis technology. Among these, Gene Therapy generated a market worth of 1.15 USD Billion in 2024, expanding to 3.0 USD Billion by 2035.
This growth emphasized the significance of Gene Therapy, as it played a crucial role in treating genetic disorders through targeted gene manipulation, offering new avenues for personalized medicine. Similarly, the Synthetic Biology segment, valued at 1.3 USD Billion in 2024 and expected to reach 3.5 USD Billion by 2035, reflects advancements in engineering biological systems to produce more sustainable resources, showcasing its importance in various industries, including agriculture, pharmaceuticals, and biofuels.
The Molecular Diagnostics segment showed a strong foothold as well, with a valuation of 1.63 USD Billion in 2024 and a projection of 4.5 USD Billion in 2035. This segment’s growth is propelled by rising demands for accurate and rapid diagnostic tools, critical for effective healthcare delivery. Lastly, Vaccine Development evolved, starting at a market value of 0.55 USD Billion in 2024 and growing to 1.0 USD Billion by 2035, underlining the persistent need for innovative vaccines in response to emerging infectious diseases.
As the Global DNA Synthesis Market data illustrates, these application areas are significant drivers of market growth, reflecting not only advancements in biotechnology but also increasing investment in Research and Development. Understanding the dynamics within these applications provides a clearer picture of how the Global DNA Synthesis Market segmentation is evolving, presenting opportunities for growth and innovation amidst various challenges the industry may face.
Source: Primary Research, Secondary Research, MRFR Database and Analyst Review
DNA Synthesis Market Product Type Insights
The Global DNA Synthesis Market is rapidly evolving and was valued at 4.63 USD Billion in 2024, demonstrating significant growth potential. This market encompasses various product types, including Oligonucleotides, Gene Fragments, and Gene Libraries, each playing a crucial role in advancing genetic research and biotechnology. Oligonucleotides are particularly significant, as they are extensively used in research and diagnostic applications due to their versatility and ease of synthesis.
Gene Fragments contribute to the increasing demand for personalized medicine by allowing for tailored gene therapies, further driving market trends. Likewise, Gene Libraries are essential for genomic research, providing a vast repository of genetic information that fuels advancements in synthetic biology. The Global DNA Synthesis Market segmentation illustrates the diverse applications and innovations within this industry, reflecting a consistent pattern of growth supported by increased investment in genetic research and development.
Insights from market data highlight how these product types are addressing ongoing challenges in diagnostics, therapeutics, and biotechnology workflows, making them integral to the future of the industry.As the market progresses towards 2035, the emphasis on these product types is expected to increase, driving further advancements in the global landscape.
DNA Synthesis Market End User Insights
The Global DNA Synthesis Market demonstrated significant potential, with the overall market valued at 4.63 USD Billion in 2024 and growing to approximately 12.0 USD Billion by 2035. This growth trajectory reflects an expected compound annual growth rate (CAGR) of 9.05 from 2025 to 2035. The End User segment of the market encompasses various critical areas such as Academic Research Institutions, Pharmaceutical Companies, Biotechnology Companies, and Clinical Laboratories.
Academic Research Institutions drive demand for DNA synthesis as they require custom DNA sequences for research and development objectives. Pharmaceutical Companies leverage this technology for drug development and precision medicine, significantly influencing market dynamics. Biotechnology Companies utilize DNA synthesis for genetic engineering and synthetic biology applications, making them a vital segment of the market.
In Clinical Laboratories, DNA synthesis is crucial for diagnostics, indicating the importance of accurate and efficient DNA synthesis. As genes play a crucial role in healthcare advancements and biotechnology innovations, the Global DNA Synthesis Market stands at a pivotal intersection with meaningful implications for research, diagnostics, and therapeutics, showcasing its importance across various sectors worldwide.Moreover, the market is poised to benefit from trends such as personalized medicine and advancements in genome editing technologies, which are expected to further enhance the demand within these segments.
DNA Synthesis Market Technology Insights
The Global DNA Synthesis Market, specifically within the Technology segment, had shown significant growth, with a market value of 4.63 billion USD by 2024. Driving this expansion are various technological advancements that facilitate DNA synthesis processes. Among these, Solid-Phase Synthesis has emerged as a preferred method due to its efficiency in producing high-quality oligonucleotides, which are vital for Research and Development in genomics.
Liquid-Phase Synthesis also plays an important role by offering versatility and scalability, appealing to various applications in pharmaceuticals and biotechnology. PCR-Based Synthesis stands out for its capacity to amplify DNA, a crucial function in diagnostics and therapeutic areas. Collectively, these technologies contribute to the diverse Global DNA Synthesis Market segmentation, enabling significant applications in gene therapy, synthetic biology, and personalized medicine.
The ongoing improvements in synthesis techniques are expected to create numerous opportunities for innovation and growth, making this sector a key player in the overall landscape of the Global DNA Synthesis Market industry.
DNA Synthesis Market Regional Insights
The Global DNA Synthesis Market showed significant regional variations, with North America leading the valuation at 1.85 USD Billion in 2024 and projected to grow to 4.7 USD Billion by 2035. This dominance is largely due to advanced Research and Development facilities and strong demand from biotechnology firms. Europe followed closely with a valuation of 1.2 USD Billion in 2024, expected to reach 3.0 USD Billion by 2035, driven by an increase in genetic research and pharmaceutical innovations.
The Asia-Pacific (APAC) region also gained traction, recording a market value of 1.0 USD Billion in 2024 and aiming for 2.7 USD Billion by 2035 as countries ramp up their efforts in synthetic biology and personalized medicine. South America and the Middle East and Africa (MEA) currently represent smaller portions of the market, with values of 0.3 USD Billion and 0.28 USD Billion in 2024, respectively, but both regions are seeing growing interest in genetic applications to address local healthcare challenges.
Overall, North America and Europe dominate, contributing to the majority holding of the Global DNA Synthesis Market revenue, while emerging markets in APAC, South America, and MEA represent significant growth opportunities and potential for expansion in the coming years.
Source: Primary Research, Secondary Research, MRFR Database and Analyst Review
DNA Synthesis Market Key Players and Competitive Insights
The Global DNA Synthesis Market has experienced substantial growth and evolution over recent years, characterized by innovation, competitive dynamics, and increasing applications in various sectors such as biotechnology, pharmaceuticals, and synthetic biology. This market is driven by a combination of technological advancements in DNA synthesis processes and a heightened demand for synthetic genetics across research and development activities.
The competitive landscape is marked by numerous players striving to enhance their offerings, with companies focusing on expanding their service capabilities, optimizing production methods, and enhancing the quality and accuracy of synthesized DNA. This environment encourages partnerships, mergers, and acquisitions as firms seek strategic alliances to bolster their market position and diversify their product portfolios.
Thermo Fisher Scientific
Thermo Fisher Scientific holds a significant position within the Global DNA Synthesis Market, fueled by its robust portfolio of products and extensive expertise in molecular biology. The company is known for its state-of-the-art technologies, including automated platforms and scalable synthesis processes, which allow for high-throughput production of DNA, catering to the needs of researchers and commercial entities alike.
The strengths of Thermo Fisher Scientific are further exemplified by its established reputation for reliability and quality in the field, making it a trusted partner for customers in diverse sectors. The company's global presence, backed by a substantial investment in research and development, empowers Thermo Fisher Scientific to continually innovate and stay ahead in the competitive landscape, responding dynamically to the evolving demands and challenges within the global market.
Ginkgo Bioworks
Ginkgo Bioworks presents a notable presence in the Global DNA Synthesis Market, distinguished by its focus on organism engineering and synthetic biology solutions. The company emphasizes creating custom DNA sequences to empower various industries, including agriculture, pharmaceuticals, and chemicals.
Ginkgo Bioworks utilizes proprietary platform technologies to streamline the design and synthesis of DNA, which not only enhances efficiency but also ensures high fidelity and scalability. Noteworthy strengths include its collaborative approach to partnerships, fueling advancements across multiple sectors through shared expertise and resources. Ginkgo Bioworks actively engages in strategic mergers and acquisitions aimed at expanding its technological capabilities and market reach.
The company's innovative product offerings and commitment to pioneering solutions place it in a strong competitive position, enabling it to cater effectively to the global demands of the DNA synthesis landscape while continuously adapting to emerging trends and customer requirements.
Key Companies in the DNA Synthesis Market Include
- Thermo Fisher Scientific
- Ginkgo Bioworks
- GeneArt
- Integrated DNA Technologies
- Synlogic
- Twist Bioscience
- LakePharma
- Fulgent Genetics
- Syndagen
- DNA2.0
- Agilent Technologies
- Eurofins Scientific
- Myraqa
- IDT
DNA Synthesis Market Industry Developments
In recent developments within the Global DNA Synthesis Market, companies such as Thermo Fisher Scientific and Ginkgo Bioworks have intensified their collaborations and partnerships to advance synthetic biology applications. The market has also witnessed significant growth, with valuations reaching new heights, indicating increased demand across pharmaceuticals, agriculture, and environmental sectors.
Major players like Twist Bioscience and Integrated DNA Technologies have reported surges in revenue, driven by the rising need for custom DNA synthesis solutions. In terms of mergers and acquisitions, in September 2023, Fulgent Genetics announced its acquisition of a leading genomics company, enhancing its capabilities in DNA synthesis and testing services.
Furthermore, IDT has expanded its facilities to boost production capacities, addressing the growing market needs. The ongoing COVID-19 pandemic continues to influence trends as companies look to leverage synthetic biology for vaccine development and bioengineering solutions. Over the past two years, companies like Synlogic and Eurofins Scientific have been actively engaged in Research and Development initiatives aiming for innovations in gene therapies and diagnostic applications, reflecting the dynamic nature of this rapidly evolving industry.
DNA Synthesis Market Segmentation Insights
DNA Synthesis Market Application Outlook
- Gene Therapy
- Synthetic Biology
- Molecular Diagnostics
- Vaccine Development
DNA Synthesis Market Product Type Outlook
- Oligonucleotides
- Gene Fragments
- Gene Libraries
DNA Synthesis Market End User Outlook
- Academic Research Institutions
- Pharmaceutical Companies
- Biotechnology Companies
- Clinical Laboratories
DNA Synthesis Market Technology Outlook
- Solid-Phase Synthesis
- Liquid-Phase Synthesis
- PCR-Based Synthesis
DNA Synthesis Market Regional Outlook
- North America
- Europe
- South America
- Asia Pacific
- Middle East and Africa
| Report Attribute/Metric Source: |
Details |
| MARKET SIZE 2023 |
4.24(USD Billion) |
| MARKET SIZE 2024 |
4.63(USD Billion) |
| MARKET SIZE 2035 |
12.0(USD Billion) |
| COMPOUND ANNUAL GROWTH RATE (CAGR) |
9.05% (2025 - 2035) |
| REPORT COVERAGE |
Revenue Forecast, Competitive Landscape, Growth Factors, and Trends |
| BASE YEAR |
2024 |
| MARKET FORECAST PERIOD |
2025 - 2035 |
| HISTORICAL DATA |
2019 - 2024 |
| MARKET FORECAST UNITS |
USD Billion |
| KEY COMPANIES PROFILED |
Thermo Fisher Scientific, Ginkgo Bioworks, GeneArt, Integrated DNA Technologies, Synlogic, Twist Bioscience, LakePharma, Fulgent Genetics, Syndagen, DNA2.0, Agilent Technologies, Eurofins Scientific, Myraqa, IDT |
| SEGMENTS COVERED |
Application, Product Type, End User, Technology, Regional |
| KEY MARKET OPPORTUNITIES |
Synthetic biology advancements, Personalized medicine applications, Increasing demand in genomics, Growth in biotechnology research, Enhanced agricultural solutions |
| KEY MARKET DYNAMICS |
Technological advancements, Increasing demand for synthetic biology, Rising applications in pharmaceuticals, Growth in personalized medicine, Expanding biotech research initiatives |
| COUNTRIES COVERED |
North America, Europe, APAC, South America, MEA |
Frequently Asked Questions (FAQ) :
The Global DNA Synthesis Market is expected to be valued at 4.63 billion USD in 2024.
By 2035, the Global DNA Synthesis Market is projected to reach a value of 12.0 billion USD.
The expected CAGR for the Global DNA Synthesis Market from 2025 to 2035 is 9.05%.
North America is expected to have the largest market share, valued at 1.85 billion USD in 2024.
The market value of the Global DNA Synthesis Market in Europe is projected to reach 3.0 billion USD by 2035.
The Gene Therapy application segment is valued at 1.15 billion USD in 2024 and should reach 3.0 billion USD by 2035.
The Molecular Diagnostics application is expected to be valued at 1.63 billion USD in 2024.
Key players in the Global DNA Synthesis Market include Thermo Fisher Scientific, Ginkgo Bioworks, and Twist Bioscience among others.
The Synthetic Biology application segment is projected to reach a value of 3.5 billion USD by 2035.
By 2035, the market value for South America in the Global DNA Synthesis Market is expected to be 0.8 billion USD.
