Animal Model Market Trends

Global Animal Model Market Overview

Animal Model Market Size was valued at USD 2.1 billion in 2021 and is projected to grow from USD 2.26 billion in 2022 to USD 4.2 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 7.1% during the forecast period (2024 - 2032).The development of CRISPR technology as a powerful tool in biomedical research and the growing use of animal models in neurological research, biomedical research, toxicology, genetic research, physiology, cancer research, and xenotransplantationare the key market drivers enhancing market growth.

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

Animal Model Market Trends

• Growth in drug discovery and development in the pharmaceutical sector to boost the market growth

On January 30, 2020, the World Health Organization (WHO) proclaimed the COVID-19 outbreak a public health emergency of significance. A total of 210 countries throughout the world have been impacted by COVID-19. The COVID-19 pandemic is an unprecedented threat to public health. It is projected to significantly affect the market for animal models used in vaccine and antiviral medication research and development. Before conducting human trials, it is crucial to confirm the safety and effectiveness of new entities using a wide number of animal models. For instance, according to the WHO, almost 20 vaccines are reportedly being developed internationally for COVID-19. These COVID-19 vaccines are in the preclinical stage, and some have already begun animal testing. The SARS-CoV-2 coronavirus has been replicated in some mouse models, including the 129SvEv, hACE2 transgenic, BALB/c, C57BL/6, and STA1 gene deletion strains (KO). Therefore, during the projection period, COVID-19 infection increased growth and prospects for important companies in animal models.

Animal models are useful for target identification and validation, toxicity and safety testing, drug screening and lead optimization, and preclinical drug efficacy and safety evaluation. The market is predicted to increase in the next years due to the rise in genetic illnesses on a scale and the expanding research community. To better understand diseases, especially infectious and chronic diseases, animal models of living non-human animals are frequently used. Pharmaceutical firms, academic organizations, and research facilities use these animal models to create new medications, cures, and treatments.

Animal models are non-human living beings employed in research and experimentation due to their immunology and pathophysiology comparable to people. They have been employed in cellular and histological research as well as the prognosis, diagnosis, treatment, and study of illnesses and the discovery and development of medications. According to the U.S. Department of Agriculture, one hundred million mice, rats, and 1 million other animals were kept in captivity for research and laboratory tests in 2019. Animal models that most closely resemble human systems are preferred since using human models for research is controversial on many levels due to the risk to human life, enhanced the animal model market CAGR across the globe in recent years.

Additionally, academic institutions use histological sections of certain organs for their microscopic research and use models in their labs to demonstrate anatomical dissections. The need for such models is predicted to rise in response to advancements in the education sector, supporting market revenue growth between 2022 and 2030, another factor driving the animal model market revenue growth.

Animal Model Market Segment Insights

Animal Model Animal Type Insights

The animal model market segmentation, based on animal type, includes pigs, cats, and mice. The mice segment held the majority share in 2021 of the animal model market revenue. About 95% of all laboratory animals are either mice or rats, with mice being the most popular model in academic and pharmaceutical research. Their small size, short lifespan, reproductive cycle, gentle temperament, and docility, and prior understanding of their biology, physiology, anatomy, genetic mapping, and simplicity of making genetically modified mice make them ideal study models.

Animal Model Technology Insights

The animal model market segmentation, based on technology, includes CRISPR, microinjection, and embryonic stem cell injection. The CRISPR segment dominated the market in 2021 and is projected to be the faster-growing segment during the forecast period 2022-2030. A group of DNA sequences known as CRISPR can be discovered in the genomes of prokaryotic organisms like bacteria and archaea. The DNA fragments of bacteriophages that previously infected the prokaryote are where these sequences were derived. During successive infections, they locate and eradicate DNA from similar bacteriophages, positively impacting the market growth.

Animal Model Application Insights

The animal model market data has been bifurcated by application into research & development, production, and quality control. The research & development segment dominated the market in 2021 and is projected to be the faster-growing segment during the forecast period 2022-2030. During the projection period, a consistent revenue growth rate is anticipated due to rising demand from laboratories worldwide for toxicity testing and nutritional, immunological, neurological, and genetic studies for basic and applied research.

Figure 2: Animal Model Market by Application, 2023 & 2030 (USD Billion) 

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

Animal Model End User Insights

Based on End Users, the animal model industry has been segmented into research institutes, educational institutes, pharmaceutical companies, and contract research organizations. Pharmaceutical companies held the largest segment share in 2021. The COVID-19 pandemic has raised the need for animal models in the pharmaceutical industry for clinical research, choosing the best medication candidate from a pool of potential leads, and other purposes. Mice models are employed in high-throughput screening or studies in which thousands of models are quickly examined using automation due to the inexpensive expenses of breeding, reproducing, and administering testing.

Animal Model Regional Insights

By Region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. North America Animal Model market accounted for USD 0.90 billion in 2021 and is expected to exhibit a significant CAGR growth during the study period. It is anticipated that the COVID-19 pandemic will result in a swift expansion of the pharmaceutical industry, raising demand for pharmaceuticals, vaccines, and monoclonal antibodies in the region's nations and propelling market revenue growth.

Further, the major countries studied in the market report are: The U.S., Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

Figure 3: ANIMAL MODEL MARKET SHARE BY REGION 2023 (%) 

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

Europe animal model market accounts for the second-largest market share. The region's substantial concentration of toxicological, nutritional, immunological, and other medical labs is anticipated to fuel market revenue growth. Further, the Germany animal model market held the largest market share, and the UK animal model market was the fastest-growing market in the European region.

The Asia-Pacific Animal Model Market is expected to grow at the fastest CAGR from 2022 to 2030. Animal model market revenue is growing due to characteristics such as ease of manipulation, short lifespan, and high reproducibility being adopted in industries across Asia-Pacific. Moreover, the China animal model market held the largest market share, and the India animal model market was the fastest-growing market in the Asia-Pacific region.

Animal Model Key Market Players & Competitive Insights

Major market players are spending a lot of money on R&D to increase their product lines, which will help the animal model market grow even more. Market participants are also taking various strategic initiatives to grow their footprint, with key market developments such as new product launches, contractual agreements, mergers and acquisitions, increased investments, and collaboration with other organizations. Competitors in the animal model industry must offer cost-effective items to expand and survive in an increasingly competitive and rising market environment.

One of the primary business strategies manufacturers adopt in the animal model industry to benefit clients and expand the market sector is manufacturing locally to reduce operating costs. In recent years, the animal model industry has provided some of the most significant benefits. The animal model market major players, such as Horizon Discovery Group plc, Charles River Laboratories International Inc., Transposagen Biopharmaceuticals Inc., and others, are working on expanding the market demand by investing in research and development activities.

Charles River Laboratories International, Inc. specializes in a range of preclinical and clinical laboratory, gene therapy, and cell therapy services for the pharmaceutical, medical device, and biotechnology industries. In May 2021, a gene therapy contract development and manufacturing organization (CDMO), Vigene Biosciences, was purchased by Charles River for $292.5 million.

Also, Envigo is a privately held contract research organization and lab animal source that offers live animals and related goods and services to the biotechnology and pharmaceutical industries, as well as to the government, the academic community, and other life science organizations that use animals in testing. In December 2019, the research models division of Horizon Discovery, which offers genetically altered models from its Boyertown, Pennsylvania, and St. Louis, Missouri, facilities, was bought by Envigo.

Key Companies in the animal model market include

• Horizon Discovery Group plc


• Charles River Laboratories International Inc.


• Transposagen Biopharmaceuticals Inc.


• Trans Genic Inc


• Envigo CRS SA


• Eurofins Scientific SE


• Crown Bioscience Inc.


• The Jackson Laboratory


• Genoway SA, among others

Animal Model Industry Developments

December 2019:The Human Protein Atlas and Horizon Discovery Group Plc. signed a collaboration agreement. The Cell Atlas Program was expanded with Horizon's CRISPR-edited knockout cell models to increase the knowledge useful for comprehending the genetic causes of the widespread disease.

April 2021:A 2-year contract that IGM Biosciences signed is crucial to creating the company's unique therapeutic IgM antibodies.

Animal Model Market Segmentation

Animal Model Animal Type Outlook

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  Pigs

  
  


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  Cats

  
  


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  Mice

  
  

Animal Model Technology Outlook

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  CRISPR

  
  


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  Microinjection

  
  


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  Embryonic Stem Cell Injection

  
  

Animal Model Application Outlook

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  Research and Development

  
  


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  Production

  
  


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  Quality Control

  
  

Animal Model End User Outlook

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  Research Institutes

  
  


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  Educational Institutes

  
  


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  Pharmaceutical Companies

  
  


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  Contract Research Organizations

  
  

Animal Model Regional Outlook

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  North America
  
  
  
  • US
  
  
  • Canada
  
  
  
  


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  Europe
  
  
  
  • Germany
  
  
  • France
  
  
  • UK
  
  
  • Italy
  
  
  • Spain
  
  
  • Rest of Europe
  
  
  
  

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  Asia-Pacific

  
  
  
  
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    China

    
    
  
  
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    Japan

    
    
  
  
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    India

    
    
  
  
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    Australia

    
    
  
  
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    South Korea

    
    
  
  
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    Australia

    
    
  
  
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    Rest of Asia-Pacific

    
    
  
  
  
  


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  Rest of the World

  
  
  
  
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    Middle East

    
    
  
  
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    Africa

    
    
  
  
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    Latin America