Articaine Hydrochloride Market Size

Global Articaine Hydrochloride Market Overview

Articaine Hydrochloride Market Size was valued at USD 1.62 Billion in 2023. The Global Articaine Hydrochloride industry is projected to grow from USD 1.75 Billion in 2024 to USD 3.27 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 9.10% during the forecast period (2024 - 2032).

Articaine is a form of a local amide anesthetic that is most commonly used in dentistry. The articaine is marketed as a colorless liquid in vials/cartridges (2ml in each vial/cartridge). It is available in two variants, i.e., Articaine-100 & Articaine-200. Articaine-200 is more potent than Articaine-100. The dosage can be based on the type and extent of surgical procedure, depth of anesthesia, degree of muscular relaxation, and condition of the patient. For pediatric patients, dosage based on their age, weight, the physical condition of the patient, and the extent of the surgical procedure.

May 2023: Altamira Therapeutics has announced that the NASAR clinical trial evaluating the effectiveness of Bentrio nasal spray for seasonal allergic rhinitis (SAR) has successfully achieved its primary efficacy goal, which is to measure the change in average reflecting Total Nasal Symptom Score (rTNSS) over a two-week period. The rTNSS exhibited a decrease in the Bentrio group, dropping from an initial score of 6.9 points to an average of 5.0 points over the course of the 14-day treatment period. In the saline spray group, the rTNSS reduced from 6.9 to 6.2 points. Additionally, the NASAR findings indicate that Bentrio demonstrates a statistically significant and clinically significant enhancement in effectiveness compared to the current standard treatment of saline nasal spray. While a saline nasal spray is designed to flush away allergen particles, Bentrio creates a thin protective barrier that prevents these particles from coming into touch with the nasal mucosa. Additionally, it aids in their removal through the natural process of mucociliary clearance. The study recruited 100 patients in Australia and assigned them randomly to two groups. Each group was instructed to use either Bentrio or saline nasal spray three times a day for two weeks or as required.

The articaine hydrochloride industry is growing rapidly. Articaine, with its greater ability to diffuse through tissues, become a very widely used local anesthetic in the European and Canadian markets.

Articaine Hydrochloride Market Trends

Articaine hydrochloride is the most popular local anesthetic for dentistry. For example, in Germany, around 97% of the anesthetic used by dentists is articaine hydrochloride. The growth of the market is likely to be driven by increasing incidences of dental caries and other periodontal diseases, advancement in dental anesthesia delivery system device, increasing the use of articaine for dental surgery, innovative nature of the dental anesthetics industry, and vigorous research and development efforts. 

Periodontal disease is one of the major dental diseases that influence human populations worldwide at high prevalence rates. Periodontal diseases are more prevalent in Asia-Pacific. Lack of the most basic oral health education and limited availability of simple interventions like pain relief and emergency care for acute infection and trauma to the vast majority of the population, especially in the rural areas are major reasons for the high incidences of periodontal diseases in the region. According to the FDI World Dental Federation, more than 80% of people in Asia-Pacific, including countries such as India, Bangladesh, Nepal, Malaysia, and Indonesia, suffer from dental decay. Furthermore, 40–59% of the population in China and Australia suffer from dental caries.

Some of the popular local anesthesia other than articaine are prilocaine, lidocaine, mepivacaine, and bupivacaine. The availability and usage of alternative products are likely to thwart the growth of the articaine hydrochloride market during the forecast period.

Articaine Hydrochloride Market Segment Insights

The articaine hydrochloride market has been segmented into application and end user.  

Articaine Hydrochloride Application Insights

Based on application, the global market has been segmented into infiltration, nerve block, and others. 

Articaine Hydrochloride End User Insights

Based on end-user, the global market has been segmented into dental clinics, hospitals, and academics & research institutes. The dental clinics segment accounted for a market value of USD 798.5 million.

Articaine Hydrochloride Regional Insights

The articaine hydrochloride market, based on region, is segmented into Europe, North America, Asia-Pacific, and the Middle East and Africa. The articaine hydrochloride market in Europe is the largest region in the market and is expected to develop continuously due to the increasing demand and focus on dental treatments. The growing awareness of preventative and corrective treatment in European countries is also one of the factors driving the growth of this market. The articaine hydrochloride market in Europe is mainly focusing on a new style of management system that would engage dental specialists to run more effective practices and permit them to concentrate on better clinical care.

North America accounted for the second-largest share in the articaine hydrochloride market. The increasing acceptance of the articaine by dental professionals is one of the factors for the growth of the articaine hydrochloride market in this region.

Asia-Pacific is one of the fastest-growing markets for articaine hydrochloride. Although Australia is dominating the Asia-Pacific market with high adoption of new technology and its usage of dental applications, China, Japan, and India are the countries mainly responsible for the exponential growth of the articaine hydrochloride market in Asia-Pacific. The demand for articaine hydrochloride in India offers several growth opportunities owing to the rising awareness of new applications. In Asia-Pacific, India accounted for a market share of 8.5%.

Articaine Hydrochloride Market Top Key Players

The prominent players in the articaine hydrochloride market are 

• 3M (US)


• Anhui BBCA Pharmaceutical Co., Ltd. (China)


• Dentsply Sirona (US)


• Inibsa Dental S.L.U (Spain)


• Jinan Chenghui Shuangda Chemical Co., Ltd. (China)


• Jinan Ruixing Pharmaceutical Technology Co., Ltd (China)


• Manus Aktteva Biopharma LLP (India)


• Pfizer Inc. (US)


• Pierrel S.p.A (Italy)


• Sanofi (France)


• Septodont (France)


• Siegfried AG (Switzerland)


• Sigma Aldrich (US)

Some of the key strategies followed by the players operating in the articaine hydrochloride market were innovation, product development, acquisition, and expansion.

Key Updates

• In March 2018, Dentsply Sirona Inc. announced the signing of a definitive agreement to acquire OraMetrix. Thus, the company aims to expand its product portfolio in the market.

• In June 2016, Pierrel S.p.A. entered into a ten-year agreement with Safco Dental Supply Co. for the production and marketing of the anesthetic articaine in the US.

• In June 2016, Septodont acquired the injectable dental anesthetic manufacturing plant from Dentsply International, located in Brazil.

Articaine Hydrochloride Market Segmentation

Articaine Hydrochloride Application Outlook

• Infiltration


• Nerve Block


• Others

Articaine Hydrochloride End User Outlook

• Dental Clinics


• Hospitals


• Academics & Research Institutes

Articaine Hydrochloride Regional Outlook

• Europe
  
  
  
  • Western Europe
    
    
    
    • Germany
    
    
    • UK
    
    
    • France
    
    
    • Italy
    
    
    • Spain
    
    
    • Rest of Western Europe
    
    
    
    
  
  
  • Eastern Europe
  
  
  
  

• North America
  
  
  
  • US
  
  
  • Canada
  
  
  
  

• Asia-Pacific
  
  
  
  • Australia
  
  
  • Japan
  
  
  • China
  
  
  • India
  
  
  • Rest of Asia-Pacific
  
  
  
  

• Middle East & Africa
  
  
  
  • Middle East
  
  
  • Africa
  
  
  
  

Available Additional Customizations

• Additional Companies
  
  
  
  • Transo-Pharm Handels GmbH
  
  
  • Orgapharm
  
  
  • Axyntis
  
  
  • Benechim s.p.r.l.
  
  
  • Green Stone Swiss Co., Ltd
  
  
  • Moehs Iberica SL
  
  
  
  

• Supply & Demand Analysis


• Investment Opportunities and Mega Trends in the market

Intended Audience

• Drug manufacturers and distributors


• Government research organizations


• Hospitals and clinics


• Regulatory agencies


• Pharmaceutical companies


• Anesthetic compounds manufacturers