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    ID: MRFR/Pharma/1293-CR
    62 Pages
    Rahul Gotadki
    February 2021

    Cystic fibrosis (CF) is a genetic disorder that primarily affects the lungs and digestive system. It results from mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene, leading to the production of thick and sticky mucus that can clog airways and ducts. Over the years, several pharmaceutical and biotechnology companies have been actively involved in researching, developing, and marketing treatments for cystic fibrosis. 

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    Top Industry Leaders in the Cystic Fibrosis Market

    Cystic Fibrosis Key Companies

     


    Latest Cystic Fibrosis Companies Update:

    Vertex Pharma raised its full-year revenue forecast in August 2023, largely due to the strong demand for its CF treatments like Trikafta. This highlights the continued market success of CFTR modulators.


    Arrow Therapeutics presented promising Phase 2b data in September 2023 for its CFTR modulator, ATI-450, demonstrating potential efficacy and tolerability in patients with CF. This could offer another treatment option for patients who do not respond well to existing therapies.


    BenevolentAI and Vertex Pharma announced a collaboration in August 2023 to leverage AI technology for identifying and developing new CF therapies. This partnership aims to accelerate the discovery of new drugs for this challenging disease.


    The FDA granted approval in July 2023 to the first gene therapy for CF, Tevardus, developed by Vertex Pharmaceuticals. This groundbreaking treatment offers the potential for a cure for some patients with CF.


    Patient advocacy groups continue to raise awareness about the high cost of CFTR modulators and advocate for improved access to these life-changing therapies for all patients who need them.


    List of Cystic Fibrosis Key companies in the market

    • Allergan PLC

    • Chiesi Farmaceutici SpA

    • AbbVie

    • Hoffmann-La Roche AG

    • Gilead Sciences

    • PTC Therapeutics

    • Novartis AG

    • Vertex Pharmaceuticals Incorporated

    • Pharmaxis Ltd