Advancements in Treating Immune Thrombocytopenia (ITP)
Imagine facing a health issue where traditional treatments aren't enough. That's the situation for some dealing with Immune Thrombocytopenia (ITP). Even with current treatments like thrombopoietin receptor agonist (TPO-RA), some people don't respond well. But here's the exciting part โ new therapies are emerging, and they seem promising!
One key finding from medical studies is that combining different therapies can be more effective and affordable. This means using a mix of treatments instead of just one. For example, researchers have looked into a combination of dexamethasone and rituximab. In trials, this combo has shown better results than using either of them alone in some patients.
Adding cyclosporine to the mix of rituximab and dexamethasone has also been tested. In small studies with adults, this combo has led to long-lasting improvements in some treated patients without causing major issues. Another promising development is a drug called Fostamatinib. It's a pill that inhibits spleen tyrosine kinase (SYK) and has shown positive outcomes in clinical trials for adults dealing with persistent or chronic ITP. In April 2018, the Food and Drug Administration (FDA) approved a drug called TAVALISSE (fostamatinib) by Rigel Pharmaceuticals, Inc. for treating chronic ITP.
What's even more exciting is that more companies are working on new drugs for ITP. For instance, CSL Limited is in Phase III of clinical trials for IgNextGen, a drug designed to treat ITP.
In simple terms, when the usual treatments for ITP don't do the trick, there's hope. New therapies are being explored, like combining different treatments or trying out innovative drugs. Some combinations, like dexamethasone and rituximab, have shown better results, and new drugs like Fostamatinib are making their way into the market. With these advancements, there's a positive outlook for treating Immune Thrombocytopenia in the coming years.
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