As per MRFR analysis, the US DNA Synthesis Market Size was estimated at 1.04 (USD Billion) in 2023.The US DNA Synthesis Market Industry is expected to grow from 1.13(USD Billion) in 2024 to 3.03 (USD Billion) by 2035. The US DNA Synthesis Market CAGR (growth rate) is expected to be around 9.343% during the forecast period (2025 - 2035)
Key US DNA Synthesis Market Trends Highlighted
The US DNA synthesis market is experiencing notable trends driven by various factors. A significant market driver is the increasing demand for synthetic DNA across various sectors, particularly in biotechnology and pharmaceuticals. The growing focus on personalized medicine has led to a rising requirement for tailored genomic solutions, fueling the synthesis of DNA for research and therapeutic applications. Furthermore, advancements in sequencing technologies and synthetic biology techniques are amplifying the efficiency and capability of DNA synthesis, making it more accessible to researchers and companies alike. Opportunities in the US DNA synthesis market are abundant, particularly with the ongoing research initiatives supported by government funding, such as those from the National Institutes of Health (NIH) and the Department of Energy (DOE).
These initiatives aim to promote advancements in genomic research, biotechnology innovations, and even agricultural biotechnology, creating market space for new entrants and established firms looking to expand their capabilities. Recent trends indicate a growing collaboration between academic institutions and private companies in the DNA synthesis space. This collaboration often focuses on developing new applications for healthcare and agricultural purposes, combining academic research with practical industrial applications. Additionally, there is increasing interest in issues like biosecurity and ethical considerations surrounding synthetic biology, further shaping the landscape of the DNA synthesis market in the US.
As the market matures, regulatory frameworks are also evolving, ensuring that innovations align with public health and safety standards, which is crucial for gaining public acceptance and further driving growth in the sector.
Source: Primary Research, Secondary Research, MRFR Database and Analyst Review
US DNA Synthesis Market Drivers
Increase in Biopharmaceutical Development
One major factor propelling the US DNA Synthesis Market Industry is the expansion of the biopharmaceutical industry in the US. With over 300 businesses engaged in the development of novel treatments, the Biotechnology Innovation Organization claims that the US leads the world in biopharmaceutical research. According to the National Institutes of Health, funding for biopharmaceutical research and development (R&D) increased by 30% between 2015 and 2020, with an estimated USD 42 billion spending in 2020 alone.
The need for synthetic DNA is increased by this increased research effort, as sophisticated medications increasingly need specific genetic components to work. As a result, it is anticipated that the biopharmaceutical boom would greatly increase the US DNA Synthesis Market.
Advancements in Genomic Research
The push for genomic research, particularly in the areas of personalized medicine and genetic therapies, serves as a critical driver for the US DNA Synthesis Market Industry. The Human Genome Project, initiated over two decades ago, sparked immense growth in genetic research, with the National Human Genome Research Institute estimating that the cost of sequencing a human genome has plummeted from nearly 3 billion USD to under 1,000 USD. This democratization of genomic information promotes research and clinical applications that rely heavily on synthetic DNA.
As universities and biotech firms ramp up their research and development efforts, the reliance on synthesized DNA continues to rise, boosting the market prospects.
Growing Applications in Synthetic Biology
The US DNA Synthesis Market Industry is also benefiting from the expanding applications in synthetic biology. According to data from the U.S. Department of Energy, synthetic biology could contribute up to 10% of the global economy by 2030, translating to potential economic impacts in the range of 3.2 trillion USD. This growth is driven by innovations across sectors such as agriculture, energy, and biomanufacturing, all of which utilize synthesized DNA for developing more efficient biological systems.
Research institutions like MIT and Stanford University are at the forefront of these developments, offering programs that actively promote the commercialization of synthetic biology, thereby driving the demand for DNA synthesis.
Increase in Genetic Testing and Diagnostics
The increased emphasis on genetic testing and diagnostics is a pivotal driver for the US DNA Synthesis Market Industry. According to the Centers for Disease Control and Prevention, genetic testing for inherited conditions has seen over a 50% increase in utilization in the last decade, indicating a growing trend among healthcare providers and patients. This trend is supported by the fact that early and personalized diagnostic testing has shown significant benefits in patient outcomes and treatment effectiveness.
Consequently, laboratories and healthcare institutions are increasingly investing in advanced DNA synthesis technologies to meet the escalating needs for efficient and accurate genetic diagnostics, thereby propelling market growth.
US DNA Synthesis Market Segment Insights
DNA Synthesis Market Application Insights
The Application segment of the US DNA Synthesis Market holds significant value, with diverse applications ranging from Gene Therapy to Vaccine Development. This market is driven by the rapid advancements in biotechnology and a growing demand for precision medicine, impacting the overall landscape in profound ways. In Gene Therapy, the focus is on using engineered DNA to modify or repair genes, offering promising treatments for genetic disorders. This area is gaining momentum due to its potential to revolutionize the clinical approach to previously untreatable diseases.
Similarly, Synthetic Biology leverages DNA synthesis to create new biological parts and systems, attracting substantial investment and interest for its ability to tackle challenges like biofuel production and agricultural enhancements. Molecular Diagnostics, meanwhile, is rapidly evolving, utilizing synthesized DNA to improve the accuracy and speed of disease detection, particularly in areas like oncology and infectious diseases, highlighting its crucial role in modern healthcare. Lastly, Vaccine Development has witnessed significant growth, especially in response to recent global health challenges, with DNA synthesis enabling faster and more efficient vaccine formulations.
The interplay of these applications illustrates the dynamic nature of the US DNA Synthesis Market, driven by innovation and a response to urgent health needs, ensuring relevance in both research and clinical settings. Overall, the market is characterized by its robust activity, aiming to address some of the most pressing health issues, demonstrating its vital role in the broader context of biomedicine and public health strategy.
Source: Primary Research, Secondary Research, MRFR Database and Analyst Review
DNA Synthesis Market Product Type Insights
The US DNA Synthesis Market is characterized by its diverse Product Type offerings, primarily including Oligonucleotides, Gene Fragments, and Gene Libraries, each playing a crucial role in various applications across Research and Development, diagnostics, and therapeutic developments. Oligonucleotides are pivotal in gene editing and molecular diagnostics, often considered the backbone of synthetic biology due to their versatility in targeting specific genetic sequences. Gene Fragments contribute significantly to the creation of recombinant proteins and gene therapies, enabling advancements in personalized medicine.
Meanwhile, Gene Libraries serve as essential tools for genetic research, providing a vast reservoir of genetic materials that aid in discovering new genes and their functions. The market dynamics reflect an increasing dependency on these products to support innovations in genomics and biotechnology, driven by rising investments in genetic research. This collective growth indicates a trend toward higher integration of genomic solutions in healthcare, fueling overall market expansion within the US.
DNA Synthesis Market End User Insights
The End User segment of the US DNA Synthesis Market showcases a diverse array of applications across various industries, highlighting its critical role in advancing genetic research and biotechnology. Academic Research Institutions are integral in driving innovation, focusing on fundamental DNA research and engaging in educational pursuits that lay the groundwork for future advancements. Pharmaceutical Companies leverage DNA synthesis for drug development, utilizing synthesized DNA for therapeutic uses and ensuring robust pipeline growth. Biotechnology Companies are pivotal as they implement DNA synthesis in the creation of genetically modified organisms and in the development of cutting-edge therapies, underlining their significance in addressing health challenges.
Meanwhile, Clinical Laboratories are essential for diagnostic applications, employing synthesized DNA in genetic testing and personalized medicine, thus catering to the growing demand for tailored healthcare solutions. As a result, the US DNA Synthesis Market segmentation into these varied End Users reflects not only current technological trends but also the potential for future growth driven by advancements in genetic engineering and bioinformatics. Overall, this segment is poised for significant evolution as it addresses both academic inquiries and real-world health issues across multiple sectors.
DNA Synthesis Market Technology Insights
The Technology segment of the US DNA Synthesis Market is characterized by diverse methodologies that facilitate precise DNA production. Solid-Phase Synthesis is known for its robustness, enabling efficient assembly of custom oligonucleotides, which play a crucial role in Research and Development across various applications such as diagnostics and therapeutics. Similarly, Liquid-Phase Synthesis offers flexibility and scalability, making it suitable for large-scale projects in genomics and synthetic biology, where rapid results are essential. PCR-Based Synthesis is significant due to its widespread use in amplifying DNA fragments, instrumental in fields like genetic research and biotechnology.
This segment has garnered immense attention owing to increasing demands for synthetic biology applications and advancements in genomic studies, reflecting a strong growth trajectory within the US. Moreover, the rise in personalized medicine and biopharmaceuticals further catalyzes the utility of these synthesis technologies, signifying their pivotal role in transforming scientific research and applications in the healthcare and agriculture sectors. As this segment continues to evolve, it presents ample opportunities for innovation and expansion, positioning itself at the forefront of the US DNA Synthesis Market industry.
US DNA Synthesis Market Key Players and Competitive Insights
The US DNA Synthesis Market has witnessed a remarkable evolution driven by advancements in biotechnology, increasing demand for personalized medicine, and the growing necessity for genetic research and synthetic biology applications. As this market expands, numerous players have emerged, each vying for competitive positioning through innovation, quality of service, and strategic partnerships. The competitive landscape is marked by both established and emerging firms that cater to various sectors, including academic research, pharmaceuticals, and agriculture. Organizations are leveraging cutting-edge technologies to enhance synthesis capabilities while addressing the complexities of customer requirements. As this dynamic environment continues to develop, understanding the competitive insights is crucial for firms aiming to excel and differentiate themselves within the marketplace.
Agilent Technologies stands out in the US DNA Synthesis Market due to its strong commitment to providing high-quality synthesis solutions tailored to meet diverse customer needs. The company boasts a comprehensive portfolio that covers an array of applications from gene synthesis to custom oligonucleotide production. Agilent's state-of-the-art manufacturing facilities enable it to maintain rigorous quality control, ensuring the reliability and performance of its products. The company's strategic focus on research and development has also led to significant advancements in synthesis technologies, enhancing its ability to deliver rapid turnaround times and scalable solutions. Agilent Technologies leverages its extensive distribution networks to maintain a robust market presence, allowing it to effectively reach various sectors, including genomics, diagnostics, and therapeutics. Furthermore, its legacy of innovation and commitment to customer service have solidified its reputation as a leading player in the industry.
Eurofins Genomics solidifies its position in the US DNA Synthesis Market by providing a range of high-quality synthetic products and services that cater to the needs of researchers and organizations in various fields. The company specializes in gene synthesis, oligos, and sequencing services, focusing on delivering fast and reliable results to meet the demands of modern scientific endeavors. Eurofins Genomics has strategically expanded its services through mergers and acquisitions, enhancing its capabilities and market footprint within the US. Their emphasis on quality assurance and technical support ensures that clients receive not only the products but also the expertise needed to drive their projects forward. Additionally, Eurofins Genomics maintains a commitment to innovation, continuously seeking advancements in its processes and technologies. This proactive approach, combined with the company's strong relationships in academia and industry, underscores its vital role in the competitive landscape of the US DNA Synthesis Market, positioning it favorably against its rivals.
Key Companies in the US DNA Synthesis Market Include
US DNA Synthesis Market Industry Developments
The US DNA Synthesis Market has seen notable advancements and developments recently. In September 2023, Agilent Technologies announced its expansion of synthetic biology capabilities, strengthening its position within the market and enhancing service offerings for clients. Concurrently, Thermo Fisher Scientific introduced new advancements to its GeneArt suite, enabling faster and more efficient DNA synthesis, which is likely to contribute to increasing market demand. Merger and acquisition activities are also noteworthy, with Twist Bioscience acquiring a leading synthetic biology firm in August 2023, thereby broadening its product portfolio.
In the past couple of years, the market has witnessed significant growth, with a substantial increase in demand for custom DNA synthesis services due to rising investments in biotechnology and genomics, aligning with initiatives by the US government to promote innovation in life sciences. Companies like Illumina and Integrated DNA Technologies continue to expand their market presence through strategic collaborations and new product launches that address diverse needs within genomic research and therapeutic development. Overall, these factors contribute to a dynamic landscape in the US DNA Synthesis Market, reflective of ongoing technological advancements and increased applications in various sectors.
DNA Synthesis Market Segmentation Insights
| Report Attribute/Metric | Details |
| Market Size 2023 | 1.04(USD Billion) |
| Market Size 2024 | 1.13(USD Billion) |
| Market Size 2035 | 3.03(USD Billion) |
| Compound Annual Growth Rate (CAGR) | 9.343% (2025 - 2035) |
| Report Coverage | Revenue Forecast, Competitive Landscape, Growth Factors, and Trends |
| Base Year | 2024 |
| Market Forecast Period | 2025 - 2035 |
| Historical Data | 2019 - 2024 |
| Market Forecast Units | USD Billion |
| Key Companies Profiled | Agilent Technologies, Eurofins Genomics, Thermo Fisher Scientific, Codexis, DNA2.0, Synlogic, Bioneer, Twist Bioscience, Genomatix, Illumina, GeneScript, Pacific Biosciences, BioRad Laboratories, Interpretive Genetics, Integrated DNA Technologies |
| Segments Covered | Application, Product Type, End User, Technology |
| Key Market Opportunities | Personalized medicine development, Synthetic biology innovations, Biopharmaceuticals manufacturing advancements, Genomic research expansion, Agricultural biotech applications |
| Key Market Dynamics | Increasing demand for personalized medicine, Advancements in synthetic biology, Growing biotech and pharmaceutical industries, Rising applications in agriculture, Enhanced research and development funding |
| Countries Covered | US |
Frequently Asked Questions (FAQ) :
The US DNA Synthesis Market is expected to be valued at 1.13 billion USD in 2024.
By 2035, the US DNA Synthesis Market is projected to reach a value of 3.03 billion USD.
The expected CAGR for the US DNA Synthesis Market from 2025 to 2035 is 9.343 percent.
In 2035, Gene Therapy is projected to hold the largest market share, valued at 1.05 billion USD.
The Synthetic Biology application is expected to be valued at 0.3 billion USD in 2024 and 0.8 billion USD by 2035.
Agilent Technologies is one of the notable key players in the US DNA Synthesis Market.
The expected market value for Molecular Diagnostics in 2035 is projected to be 0.65 billion USD.
The anticipated market size for Vaccine Development in 2024 is valued at 0.18 billion USD.
The growth in Gene Therapy, Synthetic Biology, and advancements in Molecular Diagnostics present significant opportunities from 2025 to 2035.
One of the challenges facing the US DNA Synthesis Market is the need for regulatory approvals in various applications.
Leading companies partner with us for data-driven Insights.
Kindly complete the form below to receive a free sample of this Report
Assistant Manager He holds an experience of about 7+ years in market research and business consulting, working under the spectrum of life sciences and healthcare domains. rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. his expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. in addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives
Get in Touch
© 2025 Market Research Future ® (Part of WantStats Reasearch And Media Pvt. Ltd.)
