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    Acute Bacterial Skin Skin Structure Infection Market

    ID: MRFR/HC/29440-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Acute Bacterial Skin and Skin Structure Infection Market Research Report By Infection Type (Cellulitis, Erysipelas, Impetigo, Folliculitis, Abscess), By Pathogen (Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Enterobacteriaceae, Anaerobes), By Treatment Setting (Outpatient, Inpatient, Emergency Department), By Mechanism of Action (Penicillins, Cephalosporins, Macrolides, Lincosamides, Fluoroquinolones), By Route of Administration (Oral, Intravenous, Topical) and By Regional (North America, Europe, South America, Asia...

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    Acute Bacterial Skin Skin Structure Infection Market Summary

    The Global Acute Bacterial Skin and Skin Structure Infection Market is projected to grow from 7.01 USD Billion in 2024 to 11.30 USD Billion by 2035.

    Key Market Trends & Highlights

    Acute Bacterial Skin and Skin Structure Infection Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 4.29% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 7.76 USD Billion, indicating robust growth potential.
    • in 2024, the market is valued at 7.01 USD Billion, reflecting a strong current demand for treatment options.
    • Growing adoption of advanced treatment modalities due to increasing prevalence of skin infections is a major market driver.

    Market Size & Forecast

    2024 Market Size 7.01 (USD Billion)
    2035 Market Size 11.30 (USD Billion)
    CAGR (2025-2035) 4.44%

    Major Players

    Pfizer, GlaxoSmithKline, Johnson Johnson, Merck Co., Novartis, Amryt Pharma, CTI BioPharma, Aralez Pharmaceuticals, Bayer AG, AN2 Therapeutics, Almirall, S.A., Alliance Pharma, Evotec, Cidara Therapeutics, Hikma Pharmaceuticals, Cipla, Dermavant Sciences, AstraZeneca, Galderma

    Acute Bacterial Skin Skin Structure Infection Market Trends

    Antimicrobial resistance, the growing incidence of surgical site infections, and the expanding population of immunocompromised individuals with weakened immune systems are the most important market trends.

    These developments are anticipated to present lucrative possibilities in the global market for acute bacterial skin and skin structure infections in the coming years. Furthermore, expanded research and development activities, as well as the development of innovative treatments and therapies, are expected to drive market expansion.

    The increasing prevalence of antibiotic-resistant bacteria is reshaping treatment protocols for acute bacterial skin and skin structure infections, necessitating a shift towards novel therapeutic strategies.

    Centers for Disease Control and Prevention (CDC)

    Acute Bacterial Skin Skin Structure Infection Market Drivers

    Market Trends and Projections

    Rising Healthcare Expenditure

    The Global Acute Bacterial Skin and Skin Structure Infection Market Industry is benefitting from rising healthcare expenditure across various regions. Governments and private sectors are investing more in healthcare infrastructure and services, leading to improved access to treatments for skin infections. For instance, countries with robust healthcare systems are allocating funds to enhance dermatological services, which facilitates timely interventions for skin infections. This trend is particularly notable in emerging economies, where increased spending is expected to drive market growth. As healthcare expenditure continues to rise, the market is poised for substantial expansion in the coming years.

    Increased Awareness and Education

    Growing awareness and education regarding skin infections are pivotal in shaping the Global Acute Bacterial Skin and Skin Structure Infection Market Industry. Public health campaigns aimed at educating individuals about the signs and symptoms of skin infections contribute to early diagnosis and treatment. Healthcare providers are also increasingly focusing on patient education to promote adherence to treatment regimens. This heightened awareness is likely to lead to an increase in healthcare consultations and treatment seeking behavior, thereby driving market growth. The anticipated compound annual growth rate of 4.29% from 2025 to 2035 underscores the importance of education in addressing this health issue.

    Rising Incidence of Skin Infections

    The Global Acute Bacterial Skin and Skin Structure Infection Market Industry is experiencing growth due to the increasing incidence of skin infections worldwide. Factors such as urbanization, changing lifestyles, and an aging population contribute to the rise in cases. For instance, the prevalence of conditions like diabetes and obesity, which predispose individuals to skin infections, is on the rise. This trend is particularly evident in developed nations, where healthcare systems are increasingly strained. As a result, the market is projected to reach 4.89 USD Billion in 2024, reflecting a growing demand for effective treatment options.

    Advancements in Treatment Modalities

    Innovations in treatment modalities are driving the Global Acute Bacterial Skin and Skin Structure Infection Market Industry forward. The introduction of novel antibiotics and combination therapies enhances treatment efficacy and reduces resistance. For example, the development of topical agents that target specific bacterial strains has shown promise in clinical trials. Additionally, the integration of telemedicine in dermatological care allows for timely diagnosis and treatment, further propelling market growth. As the industry adapts to these advancements, it is anticipated that the market will expand significantly, potentially reaching 7.76 USD Billion by 2035.

    Growing Burden of Antibiotic Resistance

    The escalating burden of antibiotic resistance is a critical driver for the Global Acute Bacterial Skin and Skin Structure Infection Market Industry. As bacteria evolve and develop resistance to conventional antibiotics, the need for alternative treatment options becomes more pressing. This situation has prompted researchers and pharmaceutical companies to focus on developing novel therapeutics that can effectively combat resistant strains. The urgency to address this issue is reflected in the increasing number of clinical trials and research initiatives aimed at discovering new antibiotics. Consequently, the market is likely to witness growth as healthcare providers seek effective solutions to manage resistant infections.

    Market Segment Insights

    Acute Bacterial Skin and Skin Structure Infection Infection Type Insights

    The global acute bacterial skin and skin structure infection market is segmented by Infection Type into Cellulitis, Erysipelas, Impetigo, Folliculitis, and Abscess. Among these, Cellulitis held the largest market share of around 39.5% in 2023, and the market is expected to grow at a CAGR of 4.2% during the forecast period 2025-2034

    The global acute bacterial skin and skin structure infection market for Cellulitis was valued at around USD 2.54 billion in 2023 and is expected to reach around USD 3.61 billion by 2032. The high prevalence of Cellulitis is attributed to factors such as the increasing incidence of skin injuries, surgical site infections, and the growing number of immunocompromised patients.

    Erysipelas, another common type of skin infection, accounted for a market share of approximately 22.1% in 2023. The market for Erysipelas is expected to grow at a CAGR of 4.5% during the forecast period, reaching a value of around USD 2.14 billion by 2032.

    Impetigo, a contagious skin infection caused by bacteria, held a market share of around 17.2% in 2023. The market for Impetigo is anticipated to grow at a CAGR of 4.3% during the forecast period, reaching a value of around USD 1.63 billion by 2032. Folliculitis, a skin infection that affects hair follicles, accounted for a market share of approximately 12.7% in 2023.

    The market for Folliculitis is expected to grow at a CAGR of 4.1% during the forecast period, reaching a value of around USD 1.21 billion by 2032. Abscess, a collection of pus beneath the skin, held a market share of around 8.5% in 2023.

    Acute Bacterial Skin and Skin Structure Infection Pathogen Insights

    Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Enterobacteriaceae, and Anaerobes are the major pathogens responsible for causing acute bacterial skin and skin structure infections (BSI).

    Staphylococcus aureus is the most common cause of ABSSSI, accounting for approximately 30% of cases. Streptococcus pyogenes is the second most common cause, accounting for approximately 20% of cases.

    Pseudomonas aeruginosa is a common cause of ABSSSI in hospitalized patients and immunocompromised individuals. Enterobacteriaceae and Anaerobes are less common causes of ABSSSI, but they can cause severe infections in certain populations.

    The increasing prevalence of skin and soft tissue infections, the rise in antibiotic resistance, and the growing demand for advanced treatment options are major factors driving the growth of the market.

    Acute Bacterial Skin and Skin Structure Infection Treatment Setting Insights

    The Treatment Setting segment of the global acute bacterial skin and skin structure infection market is segmented into Outpatient, Inpatient, and Emergency Departments. Among these segments, the Outpatient segment is expected to witness the fastest growth during the forecast period (2024-2032).

    The increasing preference for outpatient care due to lower costs, shorter wait times, and greater convenience is driving the growth of this segment. In 2023, the Outpatient segment accounted for a significant share of the global acute bacterial skin and skin structure infection market revenue.

    The growth of this segment can be attributed to the rising prevalence of skin and skin structure infections (SSSIs) and the increasing adoption of advanced treatment modalities in outpatient settings.

    Outpatient clinics and ambulatory surgical centers are becoming increasingly popular for the treatment of SSSIs due to their ability to provide timely and effective care. The Inpatient segment is also expected to experience steady growth during the forecast period. The increasing severity of SSSIs and the need for prolonged hospitalization are contributing to the growth of this segment.

    Hospitals provide a controlled environment for patients with severe infections to receive intensive care and monitoring. The Emergency Department segment is expected to account for a smaller share of the global acute bacterial skin and skin structure infection market revenue.

    Acute Bacterial Skin and Skin Structure Infection Mechanism of Action Insights

    The Mechanism of Action segment of the global acute bacterial skin and skin structure infection market is segmented into Penicillins, Cephalosporins, Macrolides, Lincosamides, and Fluoroquinolones. The Penicillins segment accounted for the largest share of the market in 2023 and is projected to continue to dominate the market over the forecast period.

    The Cephalosporins segment is expected to grow at the highest CAGR over the forecast period. The global acute bacterial skin and skin structure infection market is driven by the increasing prevalence of skin and soft tissue infections, the rising demand for effective and safe antibiotics, and the growing awareness of the importance of skin health.

    The market is also supported by the development of new and innovative antibiotics, as well as the increasing availability of generic drugs. The global acute bacterial skin and skin structure infection market is a highly competitive market with a number of major players.

    The key players in the market include Pfizer, GlaxoSmithKline, Johnson Johnson, Merck Co., and Novartis. These companies are investing heavily in research and development to develop new and innovative antibiotics, as well as to improve the efficacy and safety of existing antibiotics.

    Acute Bacterial Skin and Skin Structure Infection Route of Administration Insights

    The Global Acute Bacterial Skin and Skin Structure Infection (ABSSSI) Market is segmented into Oral, Intravenous, and Topical based on the Route of Administration.

    The market for Oral administration is expected to account for the largest share of the global ABSSSI Market in 2023, owing to the ease of administration and cost-effectiveness of oral medications. The Intravenous route of administration is preferred in severe cases where rapid drug delivery is required.

    The Topical route of administration is suitable for localized infections and is less likely to cause systemic side effects.

    The global acute bacterial skin and skin structure infection market for Oral administration is projected to grow at a CAGR of 4.2% during the forecast period (2024-2032).

    The Intravenous route of administration is expected to grow at a CAGR of 4.5% during the forecast period. The Topical route of administration is projected to grow at a CAGR of 4.8% during the forecast period.

    Get more detailed insights about Acute Bacterial Skin And Skin Structure Infection Market Research Report — Global Forecast till 2034

    Regional Insights

    The global acute bacterial skin and skin structure infection market is segmented into North America, Europe, APAC, South America, and MEA. The North American region is expected to hold the largest market share due to the high prevalence of skin infections and the increasing adoption of advanced treatment options.

    The European region is also expected to contribute significantly to the market growth, driven by the rising geriatric population and the increasing demand for advanced wound care products. The APAC region is expected to witness the fastest growth rate due to the increasing healthcare expenditure and the growing awareness about skin infections.

    The South American and MEA regions are also expected to contribute to the market growth, albeit at a slower pace.

    Acute Bacterial Skin and Skin Structure Infection Market Regional Insights

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    Major players in the acute bacterial skin and skin structure infection market are constantly engaged in research and development activities to enhance their product offerings and gain a competitive edge. Strategic collaborations and partnerships are also prevalent as companies seek to expand their geographic reach and access new markets.

    The acute bacterial skin and skin structure infection market is characterized by a diverse range of players, including multinational pharmaceutical companies, generic drug manufacturers, and specialty pharmaceutical companies focused on dermatology.

    Leading acute bacterial skin and skin structure infection market players are investing in innovative technologies, such as novel drug delivery systems and targeted therapies, to address unmet medical needs and improve patient outcomes.

    The acute bacterial skin and skin structure infection market development pipeline is robust, with several promising candidates in various stages of clinical development. These advancements are expected to further shape the competitive landscape and drive market growth in the coming years.

    Pfizer, a leading player in the acute bacterial skin and skin structure infection market, has a strong portfolio of antibiotics, including Zithromax and Vibramycin, which are widely used to treat bacterial skin infections. The company's focus on research and development has resulted in the development of new antibiotics, such as Sivextro, which has demonstrated efficacy against a broad spectrum of bacteria.

    Pfizer's global presence and strong distribution network enable it to reach a wide range of patients and healthcare providers. The company's commitment to innovation and patient care positions it well to maintain its leadership position in the acute bacterial skin and skin structure infection market.

    Merck, a global pharmaceutical company, is another major competitor in the acute bacterial skin and skin structure infection market. The company's antibiotic portfolio includes Cubicin, which is used to treat severe skin and skin structure infections caused by Gram-positive bacteria.

    Merck has also developed innovative technologies, such as its LipidRescue™ technology, which enhances the delivery of antibiotics to the site of infection. The company's strong research capabilities and commitment to developing new treatments for unmet medical needs make it a formidable competitor in the acute bacterial skin and skin structure infection market.

    Merck's global reach and extensive healthcare partnerships allow it to effectively distribute its products and reach a broad patient population.

    Key Companies in the Acute Bacterial Skin Skin Structure Infection Market market include

    Industry Developments

    • Q2 2024: Melinta Therapeutics Announces FDA Approval of KIMYRSA® (oritavancin) for the Treatment of Acute Bacterial Skin and Skin Structure Infections Melinta Therapeutics received FDA approval for KIMYRSA®, a single-dose intravenous antibiotic for the treatment of acute bacterial skin and skin structure infections (ABSSSI), expanding its portfolio of anti-infective therapies.

    Future Outlook

    Acute Bacterial Skin Skin Structure Infection Market Future Outlook

    The Global Acute Bacterial Skin and Skin Structure Infection Market is projected to grow at a 4.44% CAGR from 2025 to 2035, driven by rising infection rates, innovative therapies, and increased healthcare spending.

    New opportunities lie in:

    • Develop targeted therapies for resistant bacterial strains to capture niche markets.
    • Invest in telemedicine solutions for remote patient monitoring and management.
    • Enhance partnerships with healthcare providers for integrated care solutions.

    By 2035, the market is expected to exhibit robust growth, reflecting advancements in treatment and increased demand.

    Market Segmentation

    Acute Bacterial Skin and Skin Structure Infection Pathogen Outlook

    • Staphylococcus aureus
    • Streptococcus pyogenes
    • Pseudomonas aeruginosa
    • Enterobacteriaceae
    • Anaerobes

    Acute Bacterial Skin and Skin Structure Infection Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Acute Bacterial Skin and Skin Structure Infection Infection Type Outlook

    • Cellulitis
    • Erysipelas
    • Impetigo
    • Folliculitis
    • Abscess

    Acute Bacterial Skin and Skin Structure Infection Treatment Setting Outlook

    • Outpatient
    • Inpatient
    • Emergency Department

    Acute Bacterial Skin and Skin Structure Infection Mechanism of Action Outlook

    • Penicillins
    • Cephalosporins
    • Macrolides
    • Lincosamides
    • Fluoroquinolones

    Acute Bacterial Skin and Skin Structure Infection Route of Administration Outlook

    • Oral
    • Intravenous
    • Topical

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024    4.89 (USD Billion)
    Market Size 2025    5.10 (USD Billion)
    Market Size 2035 11.30 (USD Billion)
    Compound Annual Growth Rate (CAGR) 4.44% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2020 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Amryt Pharma, CTI BioPharma, Aralez Pharmaceuticals, Bayer AG, AN2 Therapeutics, Almirall, S.A., Alliance Pharma, Evotec, GlaxoSmithKline PLC, BiomX, Cidara Therapeutics, Hikma Pharmaceuticals, Cipla, Dermavant Sciences, AstraZeneca, Galderma
    Segments Covered Infection Type, Pathogen, Treatment Setting, Mechanism of Action, Route of Administration, Regional
    Key Market Opportunities Growing demand for antibiotics Rising prevalence of skin infections Technological advancements in diagnostics Increasing healthcare expenditure Emerging markets
    Key Market Dynamics Increase in prevalence of skin infections Growing demand for advanced wound care products Rising geriatric population Technological advancements in treatment options Expansion of healthcare infrastructure
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What is the market size of the global acute bacterial skin and skin structure infection market?

    The acute bacterial skin and skin structure infection market size is expected to reach USD 7.44 billion by 2034 from USD 6.42 billion in 2023, exhibiting a CAGR of 4.29% during the forecast period.

    What are the major factors driving the growth of the acute bacterial skin and skin structure infection market?

    The rising prevalence of skin infections, increasing demand for advanced treatment options, and growing awareness about the condition are key factors propelling market growth.

    Which region is expected to hold the largest share of the acute bacterial skin and skin structure infection market?

    North America is anticipated to dominate the market with a significant share due to the high prevalence of skin infections and well-established healthcare infrastructure.

    Who are the key competitors in the acute bacterial skin and skin structure infection market?

    Major players include Eli Lilly, Pfizer, Johnson Johnson, GlaxoSmithKline, Merck Co., Novartis, Sanofi, and AbbVie.

    What are the key applications of Acute Bacterial Skin and Skin Structure Infection?

    Acute Bacterial Skin and Skin Structure Infection is used to treat bacterial infections of the skin and skin structure, such as cellulitis, impetigo, and abscesses.

    What is the expected growth rate of the acute bacterial skin and skin structure infection market during the forecast period?

    The market is projected to grow at a CAGR of 4.44% from 2024 to 2032.

    What factors are likely to challenge the growth of the acute bacterial skin and skin structure infection market?

    The market may face challenges due to the emergence of antibiotic resistance and the availability of generic drugs.

    What are the key trends that are shaping the acute bacterial skin and skin structure infection market?

    Key trends include the development of novel antibiotics, the use of combination therapies, and the adoption of personalized medicine approaches.

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