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    Automated Closed Cell Therapy Processing System Market

    ID: MRFR/HC/29451-HCR
    128 Pages
    Kinjoll Dey
    October 2025

    Automated And Closed Cell Therapy Processing System Market Research Report By Cell Therapy (CAR T-Cell Therapies, TCR Gene-Edited Cell Therapies, NK Cell Therapies), By Application (Oncology, Hematology, Immunology, Neurology), By System Capability (Single-Use, Multi-Use, Closed, Semi-Closed, Open), By Scale of Production (Benchtop, Pilot Scale, Commercial Scale), By Device Type (Cell Isolators, Cell Expanders, Cell Culture Vessels, Cell Dispensers) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) ...

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    Automated Closed Cell Therapy Processing System Market Summary

    The Global Automated And Closed Cell Therapy Processing System Market is projected to grow from 1.26 USD Billion in 2024 to 3.70 USD Billion by 2035.

    Key Market Trends & Highlights

    Automated And Closed Cell Therapy Processing System Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 10.3% from 2025 to 2034.
    • By 2035, the market valuation is anticipated to reach 3.71 USD Billion, indicating robust growth potential.
    • in 2024, the market is valued at 1.26 USD Billion, reflecting the increasing demand for advanced therapy processing systems.
    • Growing adoption of automated systems due to the need for enhanced efficiency is a major market driver.

    Market Size & Forecast

    2024 Market Size 1.26 (USD Billion)
    2035 Market Size 3.70 (USD Billion)
    CAGR (2025-2035) 10.29%

    Major Players

    Terumo BCT, Fresenius Kabi, Cytiva, Sartorius, Macopharma, Cellectis, Lonza, HemaCare, GE Healthcare, Miltenyi Biotec, Kite Pharma, Roche, Thermo Fisher Scientific, Novartis, Autolus Therapeutics

    Automated Closed Cell Therapy Processing System Market Trends

    Key market drivers for automated and closed cell therapy processing systems include the growing prevalence of chronic diseases, advancements in cellular therapies, and increasing research and development in the field. Opportunities to be explored include the development of new and more efficient systems, the integration of artificial intelligence and machine learning, and the expansion of applications into new therapeutic areas. Recent trends in the market include the adoption of single-use technologies, the focus on reducing costs and improving efficiency, and the emphasis on patient safety and regulatory compliance.

    These trends are expected to continue to shape the market in the coming years.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    The evolution of automated and closed cell therapy processing systems appears to be reshaping the landscape of regenerative medicine, enhancing efficiency and precision in therapeutic applications.

    U.S. Food and Drug Administration (FDA)

    Automated Closed Cell Therapy Processing System Market Drivers

    Market Growth Projections

    The Global Automated And Closed Cell Therapy Processing System Market Industry is projected to experience substantial growth over the next decade. The market is expected to expand from 1.26 USD Billion in 2024 to 3.71 USD Billion by 2035, indicating a robust compound annual growth rate (CAGR) of 10.3% from 2025 to 2035. This growth trajectory reflects the increasing adoption of automated systems in cell therapy processing, driven by technological advancements and rising demand for personalized medicine. The market's expansion is likely to be supported by regulatory frameworks and growing investments in research and development, positioning it as a key player in the healthcare landscape.

    Technological Advancements

    The Global Automated And Closed Cell Therapy Processing System Market Industry is experiencing rapid technological advancements, which enhance the efficiency and effectiveness of cell therapy processes. Innovations in automation and robotics streamline workflows, reduce human error, and improve product consistency. For instance, automated systems can now handle complex tasks such as cell separation and culture with minimal intervention. This shift towards automation is projected to drive market growth significantly, as evidenced by the market's expected increase from 1.26 USD Billion in 2024 to 3.71 USD Billion by 2035, reflecting a compound annual growth rate (CAGR) of 10.3% from 2025 to 2035.

    Regulatory Support and Frameworks

    The Global Automated And Closed Cell Therapy Processing System Market Industry benefits from supportive regulatory frameworks that promote innovation and ensure patient safety. Regulatory bodies are increasingly recognizing the importance of cell therapies and are establishing guidelines that facilitate their development and commercialization. This regulatory support encourages investment in automated processing systems, as companies seek to comply with stringent quality standards. The market is likely to expand as these frameworks evolve, providing a conducive environment for technological advancements. The projected growth from 1.26 USD Billion in 2024 to 3.71 USD Billion by 2035 reflects the positive impact of regulatory support on market dynamics.

    Rising Prevalence of Chronic Diseases

    The Global Automated And Closed Cell Therapy Processing System Market Industry is significantly influenced by the rising prevalence of chronic diseases, which necessitate innovative treatment solutions. Conditions such as cancer, diabetes, and cardiovascular diseases are increasingly common, driving the demand for advanced therapies. Automated processing systems enable the efficient production of cell-based therapies that can address these health challenges effectively. As healthcare systems strive to improve patient outcomes, the integration of automated technologies in cell therapy processing becomes essential. The market's expected growth from 1.26 USD Billion in 2024 to 3.71 USD Billion by 2035 highlights the urgency of addressing chronic disease management through advanced therapeutic solutions.

    Increasing Demand for Personalized Medicine

    The Global Automated And Closed Cell Therapy Processing System Market Industry is witnessing a surge in demand for personalized medicine, which tailors treatments to individual patient needs. This trend is largely driven by advancements in genomics and biotechnology, enabling the development of customized therapies that target specific diseases. As healthcare providers increasingly adopt personalized approaches, the need for efficient and scalable processing systems becomes paramount. Automated systems facilitate the rapid production of tailored therapies, thereby supporting the growing market. The anticipated growth from 1.26 USD Billion in 2024 to 3.71 USD Billion by 2035 underscores the market's potential in meeting this demand.

    Growing Investment in Research and Development

    The Global Automated And Closed Cell Therapy Processing System Market Industry is poised for growth due to increasing investments in research and development (R&D) by both public and private sectors. This investment fuels innovation in cell therapies, leading to the development of novel treatments and processing technologies. As funding for R&D continues to rise, the demand for automated processing systems that can efficiently handle complex cell therapies is likely to increase. The anticipated market growth from 1.26 USD Billion in 2024 to 3.71 USD Billion by 2035 suggests that R&D investments are pivotal in shaping the future of cell therapy processing.

    Market Segment Insights

    Automated And Closed Cell Therapy Processing System Market Cell Therapy Insights

    The market growth is attributed to the increasing prevalence of chronic diseases, rising demand for personalized medicine, and technological advancements in cell therapy. Cell Therapy segment is expected to witness significant growth owing to the rising adoption of CAR T-Cell Therapies, TCR Gene-Edited Cell Therapies, and NK Cell Therapies. CAR T-Cell Therapies have shown promising results in treating hematologic malignancies, and their use is expected to expand in the coming years.

    TCR Gene-Edited Cell Therapies are also gaining traction due to their ability to target specific antigens and provide durable responses. NK Cell Therapies are being explored for their potential in treating various cancers and immune disorders. The Automated And Closed Cell Therapy Processing System Market is highly competitive, with several key players operating in the market. These players are focusing on developing innovative products and technologies to gain a competitive edge.

    The market is also witnessing a trend towards consolidation, with larger players acquiring smaller companies to expand their portfolio and geographic reach.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Automated And Closed Cell Therapy Processing System Market Application Insights

    The Automated And Closed Cell Therapy Processing System Market is segmented by Application into Oncology, Hematology, Immunology, and Neurology. The Oncology segment is expected to hold the largest share of the market in 2023, owing to the increasing prevalence of cancer and the growing demand for personalized cancer treatments. The Hematology segment is also expected to witness significant growth due to the rising incidence of blood-related disorders and the growing adoption of cell-based therapies. The Immunology and Neurology segments are expected to grow at a steady pace, driven by the increasing demand for therapies for autoimmune diseases and neurological disorders.

    Automated And Closed Cell Therapy Processing System Market System Capability Insights

    The System Capability segment of the Automated And Closed Cell Therapy Processing System Market can be categorized into Single-Use, Multi-Use, Closed, Semi-Closed, and Open systems. Among these, Single-Use systems held the largest market share in 2023, accounting for around 55% of the Automated And Closed Cell Therapy Processing System Market revenue. The increasing adoption of Single-Use systems can be attributed to their advantages, such as reduced risk of cross-contamination, improved safety, and ease of operation.

    Multi-Use systems are expected to witness significant growth over the forecast period, owing to their lower cost and higher flexibility compared to Single-Use systems. Closed systems offer a sterile and controlled environment for cell therapy processing, which is expected to drive their demand in the coming years. Semi-Closed and Open systems are also expected to contribute to the growth of the Automated And Closed Cell Therapy Processing System Market, albeit at a slower pace.

    Automated And Closed Cell Therapy Processing System Market Scale of Production Insights

    The Automated And Closed Cell Therapy Processing System Market is segmented by scale of production into benchtop, pilot scale, and commercial scale. The commercial scale segment is expected to hold the largest share of the market in 2023, accounting for over 50% of the Automated And Closed Cell Therapy Processing System Market revenue. This is due to the increasing demand for automated and closed cell therapy processing systems from large-scale cell therapy manufacturers.

    The pilot scale segment is expected to grow at the highest CAGR during the forecast period, owing to the increasing adoption of pilot-scale systems for process development and optimization. The benchtop segment is expected to account for a small share of the market, as it is primarily used for research and development purposes.

    Automated And Closed Cell Therapy Processing System Market Device Type Insights

    The Device Type segment of the Automated And Closed Cell Therapy Processing System Market is projected to witness significant growth over the forecast period, driven by the increasing demand for cell-based therapies and the need for efficient and automated cell processing systems. Within the Device Type segment, Cell Isolators are expected to account for a significant share of the market, owing to their critical role in isolating target cells from complex biological samples. Cell Expanders are also anticipated to gain traction due to their ability to expand cell populations ex vivo, which is essential for cell therapy applications.

    Cell Culture Vessels and Cell Dispensers are other key components of the Device Type segment, contributing to the overall market growth. The Automated And Closed Cell Therapy Processing System Market revenue is expected to reach USD 1.2 billion by 2024, with a CAGR of 10.29% during the forecast period. Segmentation insights like these are crucial for market players to understand the specific dynamics of different segments and tailor their strategies accordingly.

    Automated And Closed Cell Therapy Processing System Market Regional Insights

    Get more detailed insights about Automated And Closed Cell Therapy Processing System Market Research Report—Forecast till 2034

    Regional Insights

    North America is expected to account for the largest share of the market in 2023, and is expected to continue to dominate the market over the forecast period. This is due to the increasing adoption of automated and closed cell therapy processing systems in the region, as well as the presence of major market players in the region. Europe is expected to account for the second largest market share in 2023, and is expected to grow at a CAGR of around 10.5% over the forecast period.

    This is due to the increasing demand for automated and closed cell therapy processing systems in the region, as well as the presence of major market players in the region.

    Asia Pacific is expected to account for the third largest market share in 2023, and is expected to grow at a CAGR of around 11.0% over the forecast period. This is due to the increasing demand for automated and closed cell therapy processing systems in the region, as well as the presence of major market players in the region. South America and the Middle East and Africa are expected to account for the smallest market share in 2023, and are expected to grow at a CAGR of around 10.0% and 10.5%, respectively, over the forecast period.

    Source: Primary Research, Secondary Research, MRFR Database and Analyst Review

    Key Players and Competitive Insights

    Major players in Automated And Closed Cell Therapy Processing System Market industry are consistently striving to enhance their product portfolios and expand their global presence. Leading Automated And Closed Cell Therapy Processing System Market players are actively involved in strategic collaborations, mergers, and acquisitions to gain a competitive edge. The Automated And Closed Cell Therapy Processing System Market industry is characterized by intense competition among established players, as well as emerging startups that are introducing innovative technologies and solutions.

    The competitive landscape is expected to remain dynamic over the forecast period, as players continue to invest in research and development and seek opportunities for growth.

    One of the leading companies in the Automated And Closed Cell Therapy Processing System Market is Terumo BCT. The company offers a comprehensive range of automated and closed cell therapy processing systems, including the Spectra Optia and Quantum systems. Terumo BCT has a strong global presence and is continuously expanding its operations through strategic partnerships and acquisitions. The company is committed to providing innovative solutions that improve the safety and efficiency of cell therapy processing.

    A competitor company in the Automated And Closed Cell Therapy Processing System Market is Fresenius Kabi. The company offers a range of automated cell processing systems, including the Sepax and Cryostar systems. Fresenius Kabi has a strong focus on research and development and is constantly innovating to meet the evolving needs of the cell therapy industry. The company has a global presence and is committed to providing high-quality products and services to its customers.

    Key Companies in the Automated Closed Cell Therapy Processing System Market market include

    Industry Developments

    • Q2 2024: Miltenyi Biotec Launches CliniMACS Prodigy® T Cell Transduction Process for Automated CAR-T Manufacturing Miltenyi Biotec announced the launch of its CliniMACS Prodigy® T Cell Transduction Process, an automated closed system designed to streamline CAR-T cell manufacturing and improve process consistency for cell therapy developers.
    • Q1 2024: Thermo Fisher Scientific Expands Cell Therapy Manufacturing Capabilities with New Automated Platform Thermo Fisher Scientific unveiled a new automated closed cell therapy processing system aimed at increasing scalability and reducing contamination risks in cell therapy production.
    • Q2 2024: Fujifilm Irvine Scientific Opens New Cell Culture Media Manufacturing Facility in Europe Fujifilm Irvine Scientific opened a new manufacturing facility in Tilburg, Netherlands, to support the production of cell culture media for automated closed cell therapy processing systems.
    • Q1 2024: Lonza Announces Strategic Partnership with CellPoint to Advance Automated Cell Therapy Manufacturing Lonza entered a strategic partnership with CellPoint to co-develop and commercialize automated closed cell therapy processing platforms for decentralized manufacturing.
    • Q2 2024: BioNTech Acquires InstaDeep to Accelerate AI-Driven Automation in Cell Therapy Manufacturing BioNTech completed the acquisition of InstaDeep, aiming to integrate AI-driven automation into its closed cell therapy processing systems to enhance manufacturing efficiency.
    • Q1 2025: Cytiva Launches New FlexFactory Platform for Automated Cell Therapy Processing Cytiva introduced the FlexFactory platform, a modular automated closed system designed to support scalable cell therapy manufacturing and improve process control.
    • Q2 2025: Sartorius Invests $100 Million in New Cell Therapy Automation Facility in the U.S. Sartorius announced a $100 million investment to build a new facility in Massachusetts dedicated to automated closed cell therapy processing systems.
    • Q1 2025: Terumo BCT Receives FDA Clearance for Automated Cell Therapy Processing Device Terumo BCT received FDA clearance for its new automated closed cell therapy processing device, enabling streamlined and compliant manufacturing for cell therapy products.
    • Q2 2024: GE HealthCare Unveils New Automated Cell Therapy Manufacturing Suite GE HealthCare launched a new suite of automated closed cell therapy processing systems designed to support high-throughput manufacturing for clinical and commercial cell therapies.
    • Q1 2025: CellGenix Secures €30 Million Series B Funding to Expand Automated Cell Therapy Processing Solutions CellGenix raised €30 million in Series B funding to accelerate the development and commercialization of its automated closed cell therapy processing platforms.
    • Q2 2025: BioNTech Opens New Automated Cell Therapy Manufacturing Facility in Germany BioNTech inaugurated a new facility in Mainz, Germany, dedicated to automated closed cell therapy processing, expanding its manufacturing capacity for advanced therapies.
    • Q1 2024: ScaleReady Announces Partnership with Thermo Fisher Scientific to Advance Automated Cell Therapy Processing ScaleReady and Thermo Fisher Scientific formed a partnership to co-develop automated closed cell therapy processing systems, aiming to improve scalability and reduce costs for cell therapy manufacturers.

    Automated And Closed Cell Therapy Processing System Market Segmentation Insights

    Automated And Closed Cell Therapy Processing System Market Cell Therapy Outlook

      • CAR T-Cell Therapies
      • TCR Gene-Edited Cell Therapies
      • NK Cell Therapies

    Automated And Closed Cell Therapy Processing System Market Application Outlook

    Automated And Closed Cell Therapy Processing System Market System Capability Outlook

      • Single-Use
      • Multi-Use
      • Closed
      • Semi-Closed
      • Open

    Automated And Closed Cell Therapy Processing System Market Scale of Production Outlook

      • Benchtop
      • Pilot Scale
      • Commercial Scale

    Automated And Closed Cell Therapy Processing System Market Device Type Outlook

      • Cell Isolators
      • Cell Expanders
      • Cell Culture Vessels
      • Cell Dispensers

    Automated And Closed Cell Therapy Processing System Market Regional Outlook

      • North America
      • Europe
      • South America
      • Asia Pacific
      • Middle East and Africa

    Future Outlook

    Automated Closed Cell Therapy Processing System Market Future Outlook

    The Automated And Closed Cell Therapy Processing System Market is projected to grow at a 10.29% CAGR from 2024 to 2034, driven by technological advancements, increasing demand for personalized medicine, and regulatory support.

    New opportunities lie in:

    • Develop integrated platforms for real-time monitoring of cell therapy processes.
    • Invest in automation technologies to enhance efficiency and reduce operational costs.
    • Expand partnerships with biotech firms to innovate and co-develop advanced therapies.

    By 2035, the market is expected to achieve substantial growth, positioning itself as a leader in therapeutic innovations.

    Market Segmentation

    Automated And Closed Cell Therapy Processing System Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Automated And Closed Cell Therapy Processing System Market Application Outlook

    • Oncology
    • Hematology
    • Immunology
    • Neurology

    Automated And Closed Cell Therapy Processing System Market Device Type Outlook

    • Cell Isolators
    • Cell Expanders
    • Cell Culture Vessels
    • Cell Dispensers

    Automated And Closed Cell Therapy Processing System Market Cell Therapy Outlook

    • CAR T-Cell Therapies
    • TCR Gene-Edited Cell Therapies
    • NK Cell Therapies

    Automated And Closed Cell Therapy Processing System Market System Capability Outlook

    • Single-Use
    • Multi-Use
    • Closed
    • Semi-Closed
    • Open

    Automated And Closed Cell Therapy Processing System Market Scale of Production Outlook

    • Benchtop
    • Pilot Scale
    • Commercial Scale

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024    1.26 (USD Billion)
    Market Size 2025    1.39 (USD Billion)
    Market Size 2035 3.70 (USD Billion)
    Compound Annual Growth Rate (CAGR) 10.29% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2020 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Cytiva, Sartorius, Terumo BCT, Macopharma, Cellectis, Lonza, HemaCare, GE Healthcare, Miltenyi Biotec, Fresenius Kabi, Kite Pharma, Roche, Thermo Fisher Scientific, Novartis, Autolus Therapeutics
    Segments Covered Cell Therapy, Application, System Capability, Scale of Production, Device Type, Regional
    Key Market Opportunities Increasing CART cell therapies Growing demand for personalized medicine Technological advancements Expansion of cell therapy research Rising prevalence of chronic diseases
    Key Market Dynamics Rising demand for cell therapies Technological advancements Increasing prevalence of chronic diseases Government initiatives Growing adoption of personalized medicine
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What is the projected growth of the Automated And Closed Cell Therapy Processing System market?

    The Automated And Closed Cell Therapy Processing System market is the expected increase in total market value of 3.7 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the Automated And Closed Cell Therapy Processing System market?

    Automated And Closed Cell Therapy Processing System market size was valued at approximately 1.26 billion USD in 2024. This figure will reach 3.7 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the Automated And Closed Cell Therapy Processing System market?

    Automated And Closed Cell Therapy Processing System market is expected to grow at a CAGR of 10.29% between 2025 and 2035.

    How much will the Automated And Closed Cell Therapy Processing System market be worth by 2035?

    Automated And Closed Cell Therapy Processing System market is expected to be worth of 3.7 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the Automated And Closed Cell Therapy Processing System market perform over the next 10 years?

    Over the next 10 years the Automated And Closed Cell Therapy Processing System market is expected to shift from usd billion 1.26 to 3.7 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

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