Digestive Enzyme Supplements Market Analysis

Global Digestive Enzyme Supplements Market Overview

Digestive Enzyme Supplements Market is expected to cross USD 1.02 Billion by 2023 at a CAGR of 6.40% during the forecast period of 2024 to 2032. It is a perfect competition market due to the presence of numerous active buyers and sellers. The market is governed by several regional and local players recognized through their prominent brands. For instance, Danone Nutricia is a subsidiary of Danone India and provides digestive enzyme supplements in Asia-Pacific under the brand name Aptamil. Market players are focusing on product development by investing in R&D and establishing strategic partnerships with retailers and distributors to strengthen and expand their distribution networks.

Market Synopsis

The Global Digestive Enzyme Supplements Market is growing. These enzymes help manage digestive tract conditions such as exocrine or endocrine pancreatic insufficiency, constipation, irritable bowel syndrome, inflammation of the bowels, indigestion, and bloating. Digestive enzyme supplements also aid in treating other ailments such as pancreatic cancer, diabetes, and cystic fibrosis. With several proven medicinal properties, the use of digestive enzyme supplements is increasing in preventive healthcare to ensure health and vitality. The increased prevalence of ailments and conditions of the digestive tract due to changes in lifestyle has led to a rise in awareness, which is a major driver for market growth.

However, the stringent regulations laid out by the US Food and Drug Administration under the Dietary Supplement Health and Education Act of 1994 and the Natural Health Products Regulations in Canada are expected to hamper the growth of the global digestive enzyme supplements market. A hike in demand for probiotic and prebiotic supplements among the global populace is also expected to hinder market growth. According to MRFR analysis, the global prebiotics market is expected to register a CAGR of 6.40% during the forecast period of 2020 to 2027.

Market USP

Prevention of digestive health conditions with few side effects.

Market Drivers

• Increased instances of digestive tract disorders globally: Irritable bowel syndrome is the most common gastrointestinal disorder with a global prevalence rate of nearly 10%–15%. Nearly 40% of the patients suffer from mild IBS, 35% of patients suffer from moderate IBS, whereas 25% of the patients suffer from severe IBS across the globe. Thus, the increasing instances of digestive tract disorders is boosting the demand for digestive enzyme supplements.

• Increased public awareness regarding healthy lifestyles

• Ease of manufacturing

• Stringent regulations

Market Restraints

• Lack of specificity of action

• Few side effects

Market Segmentations

By Source

• Animal: Animal-based digestive enzyme supplements account for the largest market share. The growth of the segment is primarily driven by the need for pancreatic enzyme supplements and increasing prevalence of diabetes and cancer globally. As plants do not produce pancreatic enzymes that are essential to patients of exocrine pancreatic insufficiency, pancreatic cancer, diabetes, and cystic fibrosis, the animal-based digestive enzyme supplements segment is expected to maintain its dominance.

• Plant: The segment accounts for a smaller market share than animal-based digestive enzyme supplements. Plant-based digestive enzymes operate on a wider pH range between 2 and 11, resulting in higher efficacy than animal-based digestive enzymes supplements. Moreover, the products appeal to the growing vegetarian and vegan population.

• Microbial: The segment is expected to be the fastest-growing during the review period owing to the high efficacy of microbial digestive enzyme supplements and high enzyme productivity from microbial sources. Microbe-based digestive enzymes can be engineered at a molecular level to improve quality and performance and find utility for specific ailments. They can be tailor-made to create supplements with specific properties and can withstand temperatures in the range of 40–60°

By Product Type

• Tablets and Capsules: The largest and fastest-growing segment, tablets and capsules are an easy way to ingest digestive enzyme supplements while being easy to transport and store.

• Powder: Powder-based digestive enzyme supplements are useful for individuals with chronic ailments. They may be consumed in large doses that can be tailor-made for individuals.

• Others: The other segment includes digestive enzyme supplements offered in the form of gummies, granules, soft chews, probiotic drinks, and drops.

By Distribution Channel

• Store-Based: The store-based segment is expected to be larger. The segment has been further divided into supermarkets and hypermarkets, specialty stores, and others. Store-based channels of distribution offer wide consumer reach, enhanced product visibility, and a variety of products.

• Non-Store-Based: The advent of e-commerce and the widening delivery range are projected to result in a higher CAGR of the segment.

By Region

• North America: The largest regional market, with growth driven by a hike in the incidence of digestive disorders and diabetes. The proven medicinal value of digestive enzyme supplements is driving demand in the region the only remarkable restraint for market growth being the strenuous FDA approvals process.

• Europe: A prominent regional market for digestive enzyme supplements owing to the increasing geriatric population, rise in prevalence of digestive tract ailments, and an affinity for alternative therapies to manage chronic health concerns.

• Asia-Pacific: Rising awareness regarding the benefits of digestive enzyme supplements and increased availability of the products are expected to result in the regional market registering the highest CAGR during the forecast period of 2019 to 2025.

• Rest of the World: The smallest regional market with a limited population base and low public awareness about the benefits of digestive enzyme supplements.

Key Players

• Enzymes Inc. (US)


• Klaire Laboratories (US)


• Amano Enzyme Inc. (Japan)


• Enzymedica (US)


• Advanced Enzyme Technologies (India)


• National Enzyme Company (US)


• Metagenics, Inc. (US)


• Danone India (Nutricia) (India)


• Vox Nutrition (US)


• Douglas Laboratories (US)


• Integrative Therapeutics (US)


• Xymogen (US)