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Japan Neurodegenerative Disease Market

ID: MRFR/MED/50853-HCR
200 Pages
Rahul Gotadki
October 2025

Japan Neurodegenerative Disease Market Research Report By Disease Type (Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Huntington's Disease), By Diagnosis Method (Neurological Examination, Imaging Techniques, Cerebrospinal Fluid Analysis, Electrophysiological Tests), By Treatment Type (Medication, Therapy, Rehabilitation, Surgical Interventions) and By Route of Administration (Oral, Injectable, Intravenous, Transdermal)-Forecast to 2035

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Japan Neurodegenerative Disease Market Summary

As per MRFR analysis, the Japan Neurodegenerative Disease Market Size was estimated at 5.12 USD Billion in 2024. The Japan neurodegenerative disease market is projected to grow from 5.51 USD Billion in 2025 to 11.46 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 7.59% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The Japan neurodegenerative disease market is experiencing significant growth driven by demographic changes and technological advancements.

  • The rising prevalence of neurodegenerative diseases in Japan is becoming increasingly concerning, indicating a pressing need for effective treatments.
  • Technological innovations in treatment are transforming patient care, enhancing the efficacy of therapies for conditions such as Alzheimer's and Parkinson's disease.
  • Government initiatives and funding are playing a crucial role in supporting research and development, fostering a more robust healthcare ecosystem.
  • The aging population in Japan and increased research and development investment are major drivers propelling market growth.

Market Size & Forecast

2024 Market Size 5.12 (USD Billion)
2035 Market Size 11.46 (USD Billion)
CAGR (2025 - 2035) 7.59%

Major Players

Biogen (US), Eli Lilly (US), Roche (CH), Novartis (CH), AstraZeneca (GB), Merck & Co (US), Amgen (US), Sanofi (FR), Pfizer (US)

Japan Neurodegenerative Disease Market Trends

The neurodegenerative disease market in Japan is currently experiencing notable developments, driven by an aging population and increasing awareness of these conditions. As the demographic landscape shifts, the prevalence of diseases such as Alzheimer's and Parkinson's is expected to rise, prompting a greater focus on research and treatment options. The Japanese government has recognized the urgency of addressing these health challenges, leading to enhanced funding for research initiatives and the development of innovative therapies. Furthermore, collaboration between public and private sectors appears to be fostering advancements in diagnostic tools and treatment methodologies, which may improve patient outcomes. In addition to demographic factors, the neurodegenerative disease market is influenced by technological advancements in healthcare. The integration of artificial intelligence and machine learning into diagnostic processes is likely to enhance early detection and personalized treatment plans. Moreover, the growing emphasis on patient-centered care suggests a shift towards more holistic approaches in managing neurodegenerative diseases. As stakeholders continue to navigate this evolving landscape, the focus on improving quality of life for patients and their families remains paramount, indicating a promising trajectory for the market in the coming years.

Rising Prevalence of Neurodegenerative Diseases

The increasing incidence of neurodegenerative diseases in Japan is a critical trend. As the population ages, conditions such as Alzheimer's and Parkinson's are becoming more common. This trend necessitates a stronger emphasis on research, treatment options, and healthcare resources to manage these diseases effectively.

Technological Innovations in Treatment

Advancements in technology are significantly impacting the neurodegenerative disease market. The adoption of digital health solutions, including telemedicine and AI-driven diagnostics, is enhancing patient care. These innovations may lead to more accurate diagnoses and tailored treatment plans, improving overall patient outcomes.

Government Initiatives and Funding

The Japanese government is actively investing in initiatives aimed at combating neurodegenerative diseases. Increased funding for research and development is likely to accelerate the discovery of new therapies. This governmental support may also encourage collaboration between academic institutions and the pharmaceutical industry, fostering innovation.

Japan Neurodegenerative Disease Market Drivers

Aging Population in Japan

The aging population in Japan is a critical driver for the neurodegenerative disease market. As the demographic shifts towards an older age group, the incidence of neurodegenerative diseases such as Alzheimer's and Parkinson's is expected to rise. Currently, approximately 28% of the Japanese population is aged 65 and older, a figure projected to increase to 38% by 2050. This demographic trend suggests a growing need for effective treatments and care solutions within the neurodegenerative disease market. Furthermore, the increasing life expectancy, which stands at around 84 years, further exacerbates the prevalence of these diseases, thereby driving demand for innovative therapies and healthcare services tailored to this aging cohort.

Rising Awareness and Education

Rising awareness and education regarding neurodegenerative diseases play a pivotal role in shaping the market landscape. In Japan, initiatives aimed at educating the public and healthcare professionals about the symptoms and early detection of these diseases are gaining traction. This increased awareness is likely to lead to earlier diagnoses, which can significantly impact treatment efficacy. Moreover, as more individuals become informed about available therapies and support systems, the demand for services within the neurodegenerative disease market is expected to grow. Educational campaigns and community outreach programs are essential in fostering a better understanding of these conditions, ultimately driving market expansion.

Advancements in Diagnostic Technologies

Advancements in diagnostic technologies are transforming the neurodegenerative disease market. In Japan, the integration of advanced imaging techniques and biomarker identification is enhancing the accuracy of diagnoses. Technologies such as PET scans and MRI are becoming more prevalent, allowing for earlier detection of neurodegenerative diseases. This shift towards precision medicine is crucial, as it enables healthcare providers to tailor treatment plans based on individual patient profiles. The market is likely to see an increase in demand for these diagnostic tools, as they facilitate timely interventions and improve patient management strategies, thereby contributing to overall market growth.

Growing Demand for Home Healthcare Services

The growing demand for home healthcare services is emerging as a significant driver in the neurodegenerative disease market. With the increasing prevalence of neurodegenerative diseases among the aging population, many families are seeking alternatives to institutional care. Home healthcare services offer personalized care and support, allowing patients to maintain their independence while receiving necessary medical attention. In Japan, the home healthcare market is projected to grow at a CAGR of approximately 10% over the next five years. This trend indicates a shift towards more patient-centered care models, which are likely to influence the neurodegenerative disease market positively, as providers adapt to meet the needs of patients and their families.

Increased Research and Development Investment

Investment in research and development (R&D) is a significant driver of the neurodegenerative disease market. In Japan, government and private sector funding for R&D in neuroscience has seen a notable increase, with expenditures reaching approximately ¥1 trillion in recent years. This financial commitment aims to foster innovation in drug development and therapeutic approaches for neurodegenerative diseases. The focus on R&D is crucial, as it not only enhances the understanding of disease mechanisms but also accelerates the discovery of novel treatments. As a result, the neurodegenerative disease market is likely to benefit from breakthroughs in therapies that could improve patient outcomes and quality of life.

Market Segment Insights

By Disease Type: Alzheimer's Disease (Largest) vs. Parkinson's Disease (Fastest-Growing)

In the Japan neurodegenerative disease market, Alzheimer's Disease holds the largest market share among all other segment values, reflecting its significant prevalence and awareness in the population. Meanwhile, Parkinson's Disease is noted for its rapid growth, which indicates increasing visibility, advancements in treatment options, and enhanced patient support systems contributing to market expansion. The growth trends for Alzheimer's and Parkinson's Diseases are driven by several factors, including an aging population and heightened focus on early diagnosis and intervention. Increased investment in research and development for innovative therapies and medications is also facilitating growth, along with government support for mental health and neurological conditions. The rising incidence and prevalence of these conditions are shaping the market dynamics significantly.

Alzheimer's Disease: Dominant vs. Parkinson's Disease: Emerging

Alzheimer's Disease is characterized by its long-standing dominance within the Japan neurodegenerative disease market, attributed to its extensive research support and patient awareness campaigns. It has established treatment protocols and a robust healthcare infrastructure to manage its complexities. Conversely, Parkinson's Disease, while emerging, is experiencing a surge in new treatments and therapies, allowing for improved patient outcomes and increasing interest from pharmaceutical companies. The shift towards personalized medicine, patient-centered treatment plans, and advocacy for neurological health are propelling Parkinson’s market potential, making it a noteworthy competitor to Alzheimer's.

By Diagnosis Method: Neurological Examination (Largest) vs. Imaging Techniques (Fastest-Growing)

In the Japan neurodegenerative disease market, the Diagnosis Method segment demonstrates a diverse array of techniques with unique market shares. Neurological Examination commands the largest share, reflecting its traditional importance in diagnosing various neurodegenerative conditions. Imaging Techniques, while smaller, is gaining traction as advancements in technology enhance their precision and efficacy, allowing for earlier detection and better patient management. Growth trends within this segment are driven by an increasing aging population and growing awareness of neurodegenerative diseases. The rising demand for non-invasive procedures contributes to the popularity of Imaging Techniques, which are viewed as the fastest-growing option in the market. Meanwhile, Neurological Examination remains vital due to its foundational role in establishing diagnoses, supported by ongoing research into improving its accuracy and reliability.

Neurological Examination (Dominant) vs. Imaging Techniques (Emerging)

Neurological Examination serves as the dominant method for diagnosing neurodegenerative diseases in the Japan neurodegenerative disease market, leveraging a long-standing framework of clinical assessment and symptom evaluation. Its established role allows for comprehensive patient evaluations that set the groundwork for treatment strategies. However, Imaging Techniques are emerging as a critical supplementary tool; these methods, including MRI and PET scans, are rapidly evolving to provide clearer images and more detailed insights into neurological conditions. The integration of cutting-edge technology into Imaging Techniques not only supports enhanced diagnostic accuracy but also nurtures their status as a growing alternative alongside traditional methodologies. Together, these techniques shape a robust diagnostic landscape that supports evolving patient care needs.

By Treatment Type: Medication (Largest) vs. Therapy (Fastest-Growing)

In the Japan neurodegenerative disease market, the distribution among treatment types reveals that medication holds the largest share due to its longstanding establishment in managing symptoms of conditions like Alzheimer's and Parkinson's diseases. Therapy and rehabilitation options are also gaining traction, but they currently cater to a smaller segment of the population. Surgical interventions, while crucial for certain conditions, remain niche and are less frequently adopted compared to other treatment methods. The growth trends in this segment are largely driven by advancements in drug development and increased awareness of neurodegenerative diseases. The fastest-growing sector, therapy, is seeing a rise in demand as more patients seek holistic and preventative care options. Innovative therapeutic techniques and rehabilitation programs are being introduced, promoting better quality of life for patients and contributing to a positive trend in market growth.

Medication (Dominant) vs. Therapy (Emerging)

Medication in the Japan neurodegenerative disease market is characterized by a well-established range of pharmaceutical products that effectively manage symptoms and slow disease progression. It includes various classes of drugs tailored for specific conditions, providing critical support to patients. In contrast, therapy represents an emerging area where innovative practices focus on addressing the psychological and social aspects of neurodegenerative diseases. This segment includes cognitive therapies and alternative treatment options, appealing to a growing patient demographic seeking comprehensive care solutions. Together, these segments reflect the evolving landscape of treatment methodologies and the importance of integrating multiple approaches for optimal patient outcomes.

By Route of Administration: Oral (Largest) vs. Injectable (Fastest-Growing)

In the Japan neurodegenerative disease market, the Route of Administration segment is predominantly characterized by the Oral method, which holds the largest market share. The Oral route is favored due to its convenience and patient compliance, making it the preferred choice for many therapies. In contrast, the Injectable route has emerged with a significant market presence and is regarded as the fastest-growing segment, as it offers rapid absorption and effectiveness for many neurodegenerative treatments. The growth trends in this segment are driven by advancements in drug formulations and increased research into the efficacy of different routes of administration. Injectable methods are gaining traction due to their ability to deliver biologics and novel therapies that require precise dosing and rapid intervention. As the Japan neurodegenerative disease market evolves, both orally administered and injectable therapies are expected to play crucial roles in combating these diseases.

Route: Oral (Dominant) vs. Injectable (Emerging)

The Oral route of administration is dominant in the Japan neurodegenerative disease market, offering patients ease of use and better adherence to treatment regimens. Oral medications typically consist of tablets or capsules, which are well-understood and less invasive than other forms. On the other hand, the Injectable route is emerging as a vital alternative, particularly for drugs that require more rapid action or cannot be effectively absorbed through the digestive system. This method is especially relevant in cases requiring biologic treatments where precision and efficacy are paramount. The emerging Injectable segment represents a shift towards more innovative treatment options that are likely to enhance patient outcomes and satisfaction.

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Key Players and Competitive Insights

The neurodegenerative disease market in Japan is characterized by a dynamic competitive landscape, driven by an increasing prevalence of conditions such as Alzheimer's and Parkinson's disease. Key players are actively engaged in innovation and strategic partnerships to enhance their market positioning. Companies like Biogen (US) and Eli Lilly (US) are focusing on the development of novel therapies, while Roche (CH) and Novartis (CH) are leveraging their extensive research capabilities to explore new treatment modalities. This collective emphasis on innovation and collaboration is shaping a competitive environment that is increasingly focused on patient-centric solutions and advanced therapeutic options.

In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure appears moderately fragmented, with several players vying for market share. However, the influence of major companies is substantial, as they drive advancements in research and development, thereby setting the pace for competition. The strategic maneuvers of these key players are likely to dictate market trends and consumer preferences in the near future.

In October 2025, Biogen (US) announced a partnership with a leading Japanese biotechnology firm to co-develop a new treatment for Alzheimer's disease. This collaboration is expected to leverage local expertise and accelerate the clinical development process, highlighting Biogen's commitment to expanding its footprint in the Japanese market. Such strategic alliances may enhance the company's ability to navigate regulatory landscapes and meet the specific needs of Japanese patients.

In September 2025, Eli Lilly (US) launched a new digital health platform aimed at improving patient engagement and adherence to treatment protocols for neurodegenerative diseases. This initiative underscores the company's focus on integrating technology into its therapeutic offerings, potentially leading to better patient outcomes and increased market share. The move reflects a broader trend towards digitalization in healthcare, which is becoming increasingly vital in the management of chronic conditions.

In August 2025, Roche (CH) unveiled a new research initiative aimed at utilizing artificial intelligence (AI) to identify biomarkers for early detection of neurodegenerative diseases. This strategic action not only positions Roche at the forefront of innovation but also emphasizes the growing importance of AI in drug discovery and patient management. By harnessing advanced technologies, Roche aims to enhance its research capabilities and improve the precision of its therapeutic interventions.

As of November 2025, current competitive trends indicate a shift towards digitalization, sustainability, and AI integration within the neurodegenerative disease market. Strategic alliances are increasingly shaping the landscape, fostering collaboration that enhances innovation and accelerates product development. Looking ahead, competitive differentiation is likely to evolve, with a pronounced focus on innovation and technology rather than price-based competition. Companies that prioritize supply chain reliability and patient-centric solutions may gain a competitive edge in this rapidly evolving market.

Key Companies in the Japan Neurodegenerative Disease Market market include

Industry Developments

The Japan Neurodegenerative Disease Market is witnessing significant developments, particularly from key players like Eisai Co. and Takeda Pharmaceutical. In recent months, Eisai announced promising interim results for its Alzheimer's treatment, lecanemab, indicating a potential boost in market share and influence in the treatment landscape. The Japanese government continues to support healthcare innovation through its "Healthcare Policy 2020", prioritizing dementia care and funding research initiatives to enhance patient outcomes. In the context of mergers and acquisitions, Takeda Pharmaceutical recently acquired an innovative neurodegenerative disease treatment technology from a smaller firm in November 2022, strengthening its pipeline in this sector.

Chugai Pharmaceutical has also been focusing on its R&D endeavors, particularly in developing therapies for amyotrophic lateral sclerosis. The Japanese market is projected to grow significantly due to a rising aging population, with estimates suggesting that the number of dementia patients will reach approximately 7 million by 2025. Astellas Pharma's investments in gene therapy are indicative of the proactive strategies employed by companies to address the surging prevalence of neurodegenerative disorders in Japan.

 

Future Outlook

Japan Neurodegenerative Disease Market Future Outlook

The Neurodegenerative Disease Market in Japan is projected to grow at a 7.59% CAGR from 2024 to 2035, driven by increasing prevalence and advancements in treatment options.

New opportunities lie in:

  • Development of personalized medicine solutions for neurodegenerative disorders.
  • Expansion of telehealth services for remote patient monitoring.
  • Investment in AI-driven drug discovery platforms targeting neurodegenerative diseases.

By 2035, the market is expected to achieve substantial growth, driven by innovation and strategic investments.

Market Segmentation

Japan Neurodegenerative Disease Market Disease Type Outlook

  • Alzheimer's Disease
  • Parkinson's Disease
  • Multiple Sclerosis
  • Amyotrophic Lateral Sclerosis
  • Huntington's Disease

Japan Neurodegenerative Disease Market Treatment Type Outlook

  • Medication
  • Therapy
  • Rehabilitation
  • Surgical Interventions

Japan Neurodegenerative Disease Market Diagnosis Method Outlook

  • Neurological Examination
  • Imaging Techniques
  • Cerebrospinal Fluid Analysis
  • Electrophysiological Tests

Japan Neurodegenerative Disease Market Route of Administration Outlook

  • Oral
  • Injectable
  • Intravenous
  • Transdermal

Report Scope

MARKET SIZE 20245.12(USD Billion)
MARKET SIZE 20255.51(USD Billion)
MARKET SIZE 203511.46(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)7.59% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledBiogen (US), Eli Lilly (US), Roche (CH), Novartis (CH), AstraZeneca (GB), Merck & Co (US), Amgen (US), Sanofi (FR), Pfizer (US)
Segments CoveredDisease Type, Diagnosis Method, Treatment Type, Route of Administration
Key Market OpportunitiesAdvancements in biomarker discovery enhance early diagnosis in the neurodegenerative disease market.
Key Market DynamicsRising demand for innovative therapies drives competition in the neurodegenerative disease market amid regulatory scrutiny.
Countries CoveredJapan

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FAQs

What is the estimated market size of the Japan Neurodegenerative Disease Market in 2024?

The Japan Neurodegenerative Disease Market is expected to be valued at 1.46 USD Billion in 2024.

What will be the market size for the Japan Neurodegenerative Disease Market by 2035?

By 2035, the market is projected to reach a value of 2.66 USD Billion.

What is the expected compound annual growth rate (CAGR) for the Japan Neurodegenerative Disease Market from 2025 to 2035?

The expected CAGR for the market is 5.611% during the period from 2025 to 2035.

Which disease type holds the largest market value in 2024 within the Japan Neurodegenerative Disease Market?

Alzheimer's Disease holds the largest market value at 0.58 USD Billion in 2024.

What is the projected value of Parkinson's Disease in the Japan Neurodegenerative Disease Market by 2035?

The projected value of Parkinson's Disease in the market is expected to reach 0.67 USD Billion by 2035.

Who are the key players in the Japan Neurodegenerative Disease Market?

Major players include Chugai Pharmaceutical, Daiichi Sankyo, Kyowa Kirin, and Eisai Co among others.

What is the market value for Multiple Sclerosis in 2024 within Japan's Neurodegenerative Disease Market?

The market value for Multiple Sclerosis is anticipated to be 0.22 USD Billion in 2024.

What are the growth challenges faced by the Japan Neurodegenerative Disease Market?

The market faces challenges such as high drug development costs and regulatory hurdles.

What is the expected market value for Amyotrophic Lateral Sclerosis in 2035?

The expected market value for Amyotrophic Lateral Sclerosis is forecasted to be 0.25 USD Billion by 2035.

How does the market for Huntington's Disease look from 2024 to 2035?

The market for Huntington's Disease is expected to grow from 0.14 USD Billion in 2024 to 0.25 USD Billion by 2035.

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