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    Postmenopausal osteoporosis Market

    ID: MRFR/HC/20324-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    Postmenopausal Osteoporosis Market Research Report Information By Drug Class (Bisphosphonates, Selective Estrogen Receptor Modulators (SERMs), Anabolic Class, RANK Ligand Inhibitors, Calcium Metabolism Modifiers, and Others), By Route of Administration (Oral, Intravenous Route, and Subcutaneous), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2035

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    Postmenopausal osteoporosis Market Infographic
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    Postmenopausal osteoporosis Market Summary

    As per MRFR analysis, the Postmenopausal Osteoporosis Market Size was estimated at 10.2 USD Billion in 2024. The Postmenopausal Osteoporosis industry is projected to grow from 10.8 USD Billion in 2025 to 19.17 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 5.9 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    <p>The Postmenopausal Osteoporosis Market is experiencing a dynamic shift towards innovative treatments and increased awareness.</p>

    • Rising awareness and education about osteoporosis are driving patient engagement and treatment adherence in North America.
    • Technological integration in treatment options is enhancing patient outcomes, particularly in the Asia-Pacific region.
    • The aging population dynamics are contributing to a growing demand for effective osteoporosis therapies, especially in the geriatric demographic.
    • The rising incidence of osteoporosis and advancements in pharmaceutical treatments are key drivers propelling market growth, particularly in the Bisphosphonates and Oral segments.

    Market Size & Forecast

    2024 Market Size 10.2 (USD Billion)
    2035 Market Size 19.17 (USD Billion)
    CAGR (2025 - 2035) 5.9%

    Major Players

    Amgen Inc (US), Bristol-Myers Squibb Company (US), Eli Lilly and Company (US), Novartis AG (CH), Pfizer Inc (US), Sanofi S.A. (FR), Teva Pharmaceutical Industries Ltd (IL), Horizon Therapeutics plc (IE), Mylan N.V. (US)

    Postmenopausal osteoporosis Market Trends

    The Postmenopausal Osteoporosis Market is currently experiencing notable transformations driven by various factors. Increasing awareness regarding bone health among postmenopausal women appears to be a primary catalyst for market growth. Educational initiatives and healthcare campaigns are likely enhancing understanding of osteoporosis, leading to higher demand for preventive measures and treatments. Furthermore, advancements in pharmaceutical research and development suggest a promising future for innovative therapies, which may improve patient outcomes and adherence to treatment regimens. As healthcare systems evolve, the integration of technology in monitoring and managing osteoporosis is also gaining traction, potentially reshaping patient care. In addition, the demographic shift towards an aging population is influencing the Postmenopausal Osteoporosis Market. As the number of older women rises, the prevalence of osteoporosis is expected to increase, thereby amplifying the need for effective management strategies. This demographic trend may drive investment in research and development, as stakeholders seek to address the growing burden of this condition. Overall, the market landscape appears dynamic, with various elements converging to create opportunities for growth and innovation in the management of postmenopausal osteoporosis.

    Rising Awareness and Education

    There is a growing emphasis on educating postmenopausal women about osteoporosis. Awareness campaigns are likely encouraging proactive health management, leading to increased screening and treatment uptake.

    Technological Integration in Treatment

    The incorporation of digital health technologies in osteoporosis management is becoming more prevalent. Telemedicine and mobile health applications may enhance patient engagement and adherence to treatment.

    Aging Population Dynamics

    The demographic trend of an aging population is significantly impacting the Postmenopausal Osteoporosis Market. As more women reach menopause, the incidence of osteoporosis is expected to rise, necessitating improved healthcare solutions.

    The increasing prevalence of postmenopausal osteoporosis underscores the necessity for enhanced preventive measures and treatment options to mitigate the associated health risks for aging women.

    National Institutes of Health (NIH)

    Postmenopausal osteoporosis Market Drivers

    Growing Geriatric Population

    The expanding geriatric population is a significant factor influencing the Postmenopausal Osteoporosis Market. As life expectancy increases, the number of older adults, particularly women, is on the rise. This demographic shift is expected to result in a higher prevalence of osteoporosis, as age is a critical risk factor for the disease. Projections indicate that by 2030, the number of individuals aged 65 and older will surpass 1 billion, further intensifying the demand for osteoporosis management solutions. Consequently, pharmaceutical companies and healthcare providers are likely to focus their efforts on developing targeted therapies and interventions for this population. The Postmenopausal Osteoporosis Market is poised for growth as stakeholders respond to the needs of an aging society.

    Rising Incidence of Osteoporosis

    The increasing incidence of osteoporosis among postmenopausal women is a primary driver of the Postmenopausal Osteoporosis Market. Studies indicate that approximately 50 percent of women over the age of 50 will experience an osteoporosis-related fracture in their lifetime. This alarming statistic underscores the urgent need for effective treatment options and preventive measures. As the population ages, the prevalence of osteoporosis is expected to rise, leading to a greater demand for medications and therapies. The Postmenopausal Osteoporosis Market is likely to see significant growth as healthcare providers and patients seek solutions to manage and mitigate the risks associated with this condition. Furthermore, the economic burden of osteoporosis-related fractures, estimated to reach billions annually, further propels investment in research and development within this market.

    Regulatory Support and Guidelines

    Regulatory support and the establishment of clinical guidelines are pivotal drivers of the Postmenopausal Osteoporosis Market. Regulatory agencies are increasingly recognizing the importance of addressing osteoporosis, leading to the development of comprehensive guidelines for diagnosis and treatment. These guidelines not only facilitate better patient management but also encourage healthcare providers to adopt evidence-based practices. Furthermore, the approval of new therapies by regulatory bodies enhances market confidence and stimulates investment in osteoporosis research. As healthcare systems align with these guidelines, the demand for effective treatment options is likely to increase, thereby propelling the growth of the Postmenopausal Osteoporosis Market. The collaborative efforts between regulatory agencies and healthcare providers are expected to yield positive outcomes for patients and the market alike.

    Increased Focus on Preventive Healthcare

    The growing emphasis on preventive healthcare is a notable driver of the Postmenopausal Osteoporosis Market. As awareness of osteoporosis and its consequences rises, more healthcare professionals and patients are prioritizing preventive measures. This shift is reflected in the increasing adoption of lifestyle modifications, such as dietary changes and exercise regimens, aimed at reducing the risk of osteoporosis. Furthermore, healthcare systems are increasingly integrating screening programs to identify at-risk individuals early. This proactive approach not only enhances patient outcomes but also drives demand for related products and services within the Postmenopausal Osteoporosis Market. The potential for early intervention is likely to lead to a decrease in fracture rates, thereby reducing the overall healthcare costs associated with osteoporosis.

    Advancements in Pharmaceutical Treatments

    Innovations in pharmaceutical treatments for postmenopausal osteoporosis are reshaping the Postmenopausal Osteoporosis Market. Recent advancements have led to the development of new classes of medications, including monoclonal antibodies and bisphosphonates, which have shown promising results in increasing bone density and reducing fracture risk. The introduction of these novel therapies is expected to enhance patient compliance and outcomes, thereby expanding the market. Additionally, the global market for osteoporosis drugs is projected to grow significantly, with estimates suggesting a compound annual growth rate of over 5 percent in the coming years. This growth is indicative of the increasing investment in research and development, as well as the ongoing need for effective treatment options for postmenopausal women.

    Market Segment Insights

    By By Drug Class: Bisphosphonates (Largest) vs. RANK Ligand Inhibitors (Fastest-Growing)

    In the Postmenopausal Osteoporosis Market, Bisphosphonates have established themselves as the largest segment, holding a significant share due to their effectiveness in reducing fracture risk. This class has seen widespread adoption among healthcare providers, leading to high market penetration. Selective Estrogen Receptor Modulators and Anabolic Class also contribute to the overall market, but their share remains comparatively smaller. Rising awareness about osteoporosis prevention and treatment further boosts the adoption of these therapeutic options. The market is currently witnessing a surge in interest towards RANK Ligand Inhibitors, identified as the fastest-growing segment. This growth can be attributed to their novel mechanism of action, which provides an effective alternative for patients who are intolerant to traditional therapies. Additionally, favorable clinical trial results and physician endorsement are encouraging prescribers to explore these innovative options, further transforming the treatment landscape for postmenopausal osteoporosis.

    Bisphosphonates (Dominant) vs. RANK Ligand Inhibitors (Emerging)

    Bisphosphonates have become the dominant choice in the Postmenopausal Osteoporosis Market, primarily due to their robust clinical efficacy and solidified guidelines endorsing their use for fracture prevention. These agents work by inhibiting osteoclast-mediated bone resorption, which helps maintain bone density. Additionally, the extensive clinical history and familiarity among healthcare providers reinforce their market position. In contrast, RANK Ligand Inhibitors represent an emerging and innovative class that specifically targets the RANK/RANKL/OPG pathway, substantially reducing the frequency of vertebral and non-vertebral fractures. Their novel approach offers a unique solution for patients with high fracture risk, thus attracting significant therapeutic interest and investment due to their potential for high efficacy and improved patient adherence.

    By By Route of Administration: Oral (Largest) vs. Intravenous Route (Fastest-Growing)

    In the Postmenopausal Osteoporosis Market, the route of administration is critical in determining patient adherence and treatment efficacy. Oral administration currently holds the largest share, favored for its convenience and ease of use, appealing to most patients. Intravenous route and subcutaneous administration also represent significant portions of the market but show varied patient acceptance and implementation in clinical settings.

    Route of Administration: Oral (Dominant) vs. Intravenous Route (Emerging)

    The oral administration route remains dominant in the Postmenopausal Osteoporosis Market, primarily due to its user-friendly nature. Patients prefer oral medications as they offer a non-invasive, straightforward method of treatment. Meanwhile, intravenous administration, identified as the fastest-growing segment, is increasingly utilized in hospitals and clinical settings for its rapid action and higher bioavailability, appealing to patients requiring immediate results. The subcutaneous route, while present in the market, is more niche, attracting specific patient populations needing tailored therapies. As awareness and education progress, the preference towards oral and intravenous solutions seems poised for continued growth.

    By By Distribution Channel: Hospital Pharmacies (Largest) vs. Online Pharmacies (Fastest-Growing)

    In the Postmenopausal Osteoporosis Market, the distribution of pharmaceutical products through various channels reveals significant trends. Hospital pharmacies hold the largest share, serving as crucial access points for patients receiving treatments during hospital stays. Meanwhile, retail pharmacies also contribute substantially, but online pharmacies are emerging rapidly as a key player, reflecting shifting consumer preferences toward digital solutions.

    Hospital Pharmacies (Dominant) vs. Online Pharmacies (Emerging)

    Hospital pharmacies are well-established and primarily cater to patients undergoing treatment in clinical settings. They provide essential medications, including those for postmenopausal osteoporosis, ensuring immediate access to therapies tailored for individual patient needs. With healthcare providers directly influencing prescriptions, these pharmacies maintain a dominant market position. On the other hand, online pharmacies are becoming increasingly popular, driven by the growing trend of telemedicine and the convenience of home delivery. This segment attracts a tech-savvy demographic looking for easier access to osteoporosis treatments, signaling an emerging shift in pharmaceutical distribution.

    Get more detailed insights about Postmenopausal osteoporosis Market

    Regional Insights

    By region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. The North American Postmenopausal Osteoporosis market will dominate this market because of its developed medical care framework, presence of significant industry players, high diagnosis and therapy rate, more patient consistency, and huge patient base. The US contributes the most extreme offer in North America. About 18.8% of women who were 50 years of age or older had osteoporosis, according to data released by the Centers for Disease Control and Prevention (CDC) in 2021.

    Sedentary lifestyles and bad eating and drinking habits are expected to contribute to the pervasiveness even further. Approximately 71 million Americans are expected to have reduced bone density and osteoporosis by 2030, according to the Public Osteoporosis Establishment.

    Further, the major countries studied in the market report are the US, Canada, Germany, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

    Figure 2:  POSTMENOPAUSAL OSTEOPOROSIS MARKET SHARE BY REGION 2023 (USD Billion)

    POSTMENOPAUSAL OSTEOPOROSIS MARKET SHARE BY REGION 2023

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    Europe's Postmenopausal Osteoporosis market accounts for the second-largest market share. Europe's population is among the oldest in the world, and a significant number of postmenopausal women live in regions where osteoporosis is more common. The demographic shift towards an aging population creates an important market for osteoporosis prevention, diagnosis, and treatment. Further, the German Postmenopausal Osteoporosis market held the largest market share, and the UK Postmenopausal Osteoporosis market was the fastest-growing market in the European region.

    The Asia-Pacific Postmenopausal Osteoporosis Market is expected to grow at the fastest CAGR from 2024 to 2032. Numerous nations in the Asia Pacific are putting resources into extending their healthcare framework, further developing admission to healthcare administrations, and reinforcing primary care systems. This development of healthcare facilities and services upgrades opportunities for osteoporosis screening, analysis, and therapy. Moreover, China’s Postmenopausal Osteoporosis market held the largest market share, and the Indian Postmenopausal Osteoporosis market was the fastest-growing market in the Asia-Pacific region.

    Key Players and Competitive Insights

    The industry's leading players will keep investing heavily in R&D to expand their product lines, which will propel the growth of the postmenopausal osteoporosis market. Contractual contracts, mergers and acquisitions, increased investments, collaboration with other companies, and the production of new products are examples of significant market developments. To increase their worldwide reach, market players also take part in a variety of strategic initiatives. In order to survive and expand in a more competitive and dynamic market, the Postmenopausal Osteoporosis industry must offer reasonably priced products and services.

    One of the main strategies manufacturers use in the worldwide Postmenopausal Osteoporosis market is local manufacturing, which expands the market sector and helps customers by lowering operating costs. Some of the biggest medical benefits in recent years have come from the Postmenopausal Osteoporosis sector. Major players in the Postmenopausal Osteoporosis market, including Pfizer Inc., Amgen, F.

    Hoffmann-La Roche Ltd, Novartis AG, Chugai Pharma China Co., Ltd., Teva Pharmaceutical Industries Ltd., Fresenius Kabi AG, Hikma Pharmaceuticals PLC, GlaxoSmithKline plc, Sun Pharmaceutical Industries Ltd, Paras Biopharmaceuticals Finland Oy, Ligand Pharmaceuticals Incorporated, and Eli Lilly and Company, and others, are attempting to increase market demand by investing in research and development operations.

    Pfizer Inc (Pfizer) discovers, creates, makes, and markets biopharmaceuticals. The organization offers items to treat different circumstances, such as cardiovascular, metabolic, and pain, ladies' well-being, malignant growth, inflammation, resistant problems, and rare illnesses. It additionally gives clean injectable drugs, biosimilars, active pharmaceutical ingredients (APIs), and agreement-producing services. Pfizer sells its items through wholesalers, retailers, medical clinics, individual supplier workplaces, facilities, government organizations, and drug stores. Pfizer Inc. brought back to the U.S. market DUAVEE (conjugated estrogens/bazedoxifene), a menopausal hormone treatment with estrogen, in June 2023 with improved packaging.

    This return follows a voluntary recall due to a packaging problem that had nothing to do with any worries about the efficacy or safety of the product. It is anticipated that this relaunch plan will address the packaging concerns and increase sales income.

    Amgen Inc., a biotechnology business, finds, makes, produces, and distributes state-of-the-art human meds to treat patients with hazardous sicknesses. It makes state-of-the-art prescriptions to address afflictions connected with the heart, hematological and oncology, irritation, bone well-being, neurological sicknesses, and nephrology. To make merchandise that uses state-of-the-art human hereditary qualities, the association inspects the difficulties presented by sickness and appreciates the standards of human science. Amgen mainly supplies pharmaceutical wholesale wholesalers in the United States with its goods. Additionally, it markets some items directly to customers through collaborations with other businesses and direct-to-consumer channels.

    Amgen's latest findings from real-world research in 2023 show that Prolia was very successful in lowering the risk of fracture in individuals with postmenopausal osteoporosis.

    Key Companies in the Postmenopausal osteoporosis Market market include

    Industry Developments

    July 2022: Edirol (eldecalcitol) was introduced in China by Chugai Pharma China Co., Ltd., a division of Chugai Pharmaceutical Co., Ltd., following clearance by the China National Medical Products Administration (NMPA) for the management of postmenopausal osteoporosis. Chugai developed edirol, an effective vitamin D3 derivative.

    January 2021: Released by the Asia Pacific Consortium on Osteoporosis (APCO), the guidelines provide clinical practice for osteoporosis screening, diagnosis, and care throughout the Asia-Pacific region. The guidelines prioritize the needs of several high-risk populations. In addition to strengthening the Asia-Pacific sector, the project is expected to increase awareness in the region even further.

    In May 2024, Fresenius Kabi stated that the FDA has approved for evaluation the company's Biologics License Application (BLA) for FKS518, its biosimilar candidate to Prolia (denosumab) and Xgeva (denosumab) for the treatment of postmenopausal osteoporosis

    In June 2023, Pfizer Inc. returned DUAVEE (conjugated estrogens/bazedoxifene), a menopausal hormone treatment including estrogen, to the US market with improved packaging. This return follows a voluntary recall caused by a packaging problem that was unconnected to any concerns about the product's efficacy or safety. This relaunch technique is supposed to ease packaging difficulties while also generating income through sales.

    In February 2023, Sandoz obtained a Biologics License Application (BLA) from the US Food and Drug Administration (FDA) for a potential denosumab biosimilar (Prolia and Xgeva; Amgen). The medicine is meant to treat a wide range of illnesses, including osteoporosis in postmenopausal women and men at high risk of fracture and a variety of other medical disorders

    .webp

    Future Outlook

    Postmenopausal osteoporosis Market Future Outlook

    The Global Postmenopausal Osteoporosis Market is projected to grow at a 5.90% CAGR from 2025 to 2035, driven by increasing aging populations, advancements in treatment options, and heightened awareness of bone health.

    New opportunities lie in:

    • Develop innovative digital health solutions for osteoporosis management.
    • Expand product lines to include personalized treatment options based on genetic profiling.
    • Leverage telemedicine for remote patient monitoring and education initiatives.

    By 2035, the market is expected to exhibit robust growth, reflecting enhanced treatment accessibility and patient engagement.

    Market Segmentation

    Postmenopausal Osteoporosis Regional Outlook

    North America
    • US
    • Canada
    Europe
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    Asia-Pacific
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    Rest of the World
    • Middle East
    • Africa
    • Latin America

    Postmenopausal Osteoporosis Drug Class Outlook

    • Bisphosphonates
    • Selective Estrogen Receptor Modulators (SERMs)
    • Anabolic Class
    • RANK Ligand Inhibitors
    • Calcium Metabolism Modifiers
    • Others

    Postmenopausal Osteoporosis Distribution Channel Outlook

    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies

    Postmenopausal Osteoporosis Route of Administration Outlook

    • Oral
    • Intravenous Route
    • Subcutaneous

    Report Scope

    Postmenopausal Osteoporosis Report Scope

    Report Attribute/Metric Details
    Market Size 2024 USD 10.2 Billion
    Market Size 2035 19.17 (Value (USD Billion))
    Compound Annual Growth Rate (CAGR) 5.90% (2025 - 2035)
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019-2022
    Market Forecast Units Value (USD Billion)
    Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments Covered Drug Class, Route of Administration, Distribution Channel, and Region
    Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
    Countries Covered The US, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
    Key Companies Profiled Pfizer Inc., Amgen, F. Hoffmann-La Roche Ltd, Novartis AG, Chugai Pharma China Co., Ltd., Teva Pharmaceutical Industries Ltd., Fresenius Kabi AG, Hikma Pharmaceuticals PLC, GlaxoSmithKline plc, Sun Pharmaceutical Industries Ltd, Paras Biopharmaceuticals Finland Oy, Ligand Pharmaceuticals Incorporated, and Eli Lilly and Company
    Key Market Opportunities ·         Development of novel therapeutics and fracture prevention programs
    Key Market Dynamics ·         Rising osteoporosis incidence among elderly females and increasing R&D and new drug approvals.
    Market Size 2025 10.80 (Value (USD Billion))

     

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    FAQs

    What is the projected growth of the Postmenopausal osteoporosis market?

    The Postmenopausal osteoporosis market is the expected increase in total market value of 19.17 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the Postmenopausal osteoporosis market?

    Postmenopausal osteoporosis market size was valued at approximately 10.2 billion USD in 2024. This figure will reach 19.17 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the Postmenopausal osteoporosis market?

    Postmenopausal osteoporosis market is expected to grow at a CAGR of 5.9% between 2025 and 2035.

    How much will the Postmenopausal osteoporosis market be worth by 2035?

    Postmenopausal osteoporosis market is expected to be worth of 19.17 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the Postmenopausal osteoporosis market perform over the next 10 years?

    Over the next 10 years the Postmenopausal osteoporosis market is expected to shift from usd billion 10.2 to 19.17 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

    Which region held the largest market share in the Postmenopausal Osteoporosis market?

    North America had the largest share of the market.

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