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    Postoperative Nausea Vomiting Market

    ID: MRFR/HC/41643-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    Postoperative Nausea and Vomiting Market Research Report By Type of Treatment (Pharmacological Treatment, Non-Pharmacological Treatment, Combination Therapy), By Medication Class (5-HT3 Antagonists, Dopamine Antagonists, Antihistamines, Corticosteroids), By Administration Route (Oral, Intravenous, Rectal), By Patient Demographics (Pediatric Patients, Adult Patients, Geriatric Patients) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Postoperative Nausea Vomiting Market Summary

    As per MRFR analysis, the Postoperative Nausea and Vomiting Market Size was estimated at 4.251 USD Billion in 2024. The Postoperative Nausea and Vomiting industry is projected to grow from 4.419 USD Billion in 2025 to 6.503 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 3.94 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The Postoperative Nausea and Vomiting Market is poised for growth driven by innovative treatments and a focus on patient care.

    • The emergence of novel therapeutics is reshaping treatment paradigms in the postoperative nausea and vomiting market.
    • North America remains the largest market, while the Asia-Pacific region is recognized as the fastest-growing area for these therapies.
    • Pharmacological treatment continues to dominate the market, with 5-HT3 antagonists leading in terms of market share.
    • Rising surgical procedures and advancements in antiemetic therapies are key drivers propelling market expansion.

    Market Size & Forecast

    2024 Market Size 4.251 (USD Billion)
    2035 Market Size 6.503 (USD Billion)
    CAGR (2025 - 2035) 3.94%

    Major Players

    Fresenius Kabi (DE), Baxter International (US), GlaxoSmithKline (GB), Merck & Co. (US), AstraZeneca (GB), Novartis (CH), Teva Pharmaceutical Industries (IL), Eisai Co., Ltd. (JP), Hikma Pharmaceuticals (GB)

    Postoperative Nausea Vomiting Market Trends

    The Postoperative Nausea and Vomiting Market is currently experiencing notable shifts driven by advancements in medical technology and evolving patient care protocols. The increasing awareness of the adverse effects associated with postoperative nausea and vomiting has prompted healthcare providers to seek more effective management strategies. This market is characterized by a diverse range of treatment options, including pharmacological interventions and non-pharmacological approaches, which cater to the varying needs of patients. Furthermore, the integration of personalized medicine into postoperative care appears to enhance patient outcomes, as tailored therapies may reduce the incidence and severity of nausea and vomiting following surgical procedures. In addition, the growing emphasis on patient safety and comfort is likely to influence the development of innovative solutions within the Postoperative Nausea and Vomiting Market. Healthcare institutions are increasingly prioritizing the implementation of evidence-based practices to mitigate postoperative complications. This trend suggests a shift towards more comprehensive care models that not only address the immediate symptoms but also consider the overall well-being of patients during their recovery. As the market continues to evolve, stakeholders must remain vigilant in adapting to these changes to ensure optimal patient care and satisfaction.

    Emergence of Novel Therapeutics

    The Postoperative Nausea and Vomiting Market is witnessing the introduction of innovative therapeutic agents designed to enhance efficacy and minimize side effects. These novel treatments may offer improved outcomes for patients, potentially transforming standard care practices.

    Focus on Patient-Centric Approaches

    There is a growing trend towards patient-centric care models that prioritize individual needs and preferences. This shift may lead to the development of tailored treatment plans that enhance patient satisfaction and recovery experiences.

    Integration of Technology in Management

    The incorporation of advanced technologies, such as digital health tools and telemedicine, is becoming increasingly prevalent in the management of postoperative nausea and vomiting. This trend suggests a potential for improved monitoring and support for patients during their recovery.

    The increasing focus on patient safety and comfort in surgical procedures appears to be driving innovations in the management of postoperative nausea and vomiting, suggesting a shift towards more effective therapeutic options.

    U.S. Food and Drug Administration (FDA)

    Postoperative Nausea Vomiting Market Drivers

    Rising Surgical Procedures

    The increasing number of surgical procedures performed annually appears to be a primary driver for the Postoperative Nausea and Vomiting Market. As surgical techniques advance and become more accessible, the volume of surgeries, including elective and emergency operations, continues to rise. According to recent data, millions of surgeries are conducted each year, leading to a corresponding increase in postoperative complications, including nausea and vomiting. This trend necessitates effective management strategies to mitigate these adverse effects, thereby propelling the demand for antiemetic therapies and interventions within the market. The growing awareness among healthcare providers regarding the importance of addressing postoperative nausea and vomiting further emphasizes the need for innovative solutions in this sector.

    Advancements in Antiemetic Therapies

    The Postoperative Nausea and Vomiting Market is significantly influenced by advancements in antiemetic therapies. Recent developments in pharmacological treatments, including the introduction of new drug classes and formulations, have enhanced the efficacy of nausea and vomiting management. For instance, the emergence of 5-HT3 receptor antagonists and neurokinin-1 receptor antagonists has provided healthcare professionals with more effective options to prevent and treat postoperative nausea. Market data indicates that these advancements are likely to increase the adoption of these therapies in clinical settings, as they offer improved outcomes for patients. Consequently, the ongoing research and development in this area are expected to drive market growth, as healthcare providers seek to implement the most effective treatment protocols.

    Increased Awareness of Patient Comfort

    The growing emphasis on patient comfort and satisfaction in postoperative care is a notable driver for the Postoperative Nausea and Vomiting Market. Healthcare institutions are increasingly recognizing the impact of postoperative nausea and vomiting on patient recovery and overall satisfaction. Studies have shown that effective management of these symptoms can lead to shorter hospital stays and improved patient outcomes. As a result, hospitals and surgical centers are investing in protocols and training aimed at minimizing these adverse effects. This shift towards patient-centric care is likely to stimulate demand for effective antiemetic treatments, as healthcare providers strive to enhance the overall patient experience during recovery.

    Regulatory Support for Antiemetic Drugs

    Regulatory support for the approval and use of antiemetic drugs is a crucial driver for the Postoperative Nausea and Vomiting Market. Regulatory agencies are increasingly recognizing the importance of effective nausea management in surgical patients, leading to streamlined approval processes for new therapies. This supportive regulatory environment encourages pharmaceutical companies to invest in research and development of innovative antiemetic solutions. As a result, the market is likely to see a surge in new product launches, which can address unmet needs in postoperative care. The proactive stance of regulatory bodies in promoting safe and effective treatments is expected to significantly contribute to the growth of the market.

    Technological Integration in Healthcare

    The integration of technology in healthcare practices is transforming the Postoperative Nausea and Vomiting Market. Innovations such as telemedicine, mobile health applications, and electronic health records are facilitating better monitoring and management of postoperative symptoms. These technologies enable healthcare providers to track patient outcomes more effectively and adjust treatment plans accordingly. Furthermore, the use of predictive analytics can help identify patients at higher risk for postoperative nausea and vomiting, allowing for preemptive interventions. As technology continues to evolve, its application in managing postoperative complications is expected to enhance treatment efficacy and patient safety, thereby driving market growth.

    Market Segment Insights

    By Type of Treatment: Pharmacological Treatment (Largest) vs. Non-Pharmacological Treatment (Fastest-Growing)

    The Postoperative Nausea and Vomiting (PONV) treatment market is currently dominated by pharmacological treatments, which hold a substantial share in the overall market. Patients undergoing surgery often face nausea and vomiting as side effects of anesthesia, leading to a heightened demand for effective pharmacological solutions. Non-pharmacological treatments, while gaining traction, still lag behind but are increasingly recognized for their complementary benefits in managing postoperative symptoms and improving patient comfort.

    Treatment options: Pharmacological (Dominant) vs. Non-Pharmacological (Emerging)

    Pharmacological treatments, including antiemetics and other medications, represent the dominant approach in the Postoperative Nausea and Vomiting market due to their established efficacy and rapid action. They are commonly preferred by healthcare professionals for immediate relief. In contrast, non-pharmacological treatments, such as acupressure and behavioral therapies, are emerging as popular alternatives, focusing on holistic patient care. While they currently account for a smaller market share, their growth is driven by increasing patient awareness and preference for personalized treatment options, suggesting a shift towards integrative approaches in managing PONV.

    By Medication Class: 5-HT3 Antagonists (Largest) vs. Dopamine Antagonists (Fastest-Growing)

    In the Postoperative Nausea and Vomiting Market, the 5-HT3 antagonists segment holds the largest share, widely recognized for their efficacy in preventing nausea and vomiting induced by chemotherapy and surgery. These medications, including ondansetron and granisetron, have established a solid foothold due to their reliable performance and favorable safety profile. While they dominate the market, dopamine antagonists are rapidly gaining traction, driven by a growing reliance on their effectiveness in managing nausea associated with postoperative recovery. The growth trends indicate a robust demand for dopamine antagonists, particularly in the context of rising surgical procedures and the need for effective postoperative care solutions. The innovative formulations and expanding applications of these medications are pivotal in driving their market penetration. Key industry players are focusing on research and development to enhance the therapeutic profiles of these drugs, positioning dopamine antagonists poised for significant growth in the coming years.

    5-HT3 Antagonists (Dominant) vs. Dopamine Antagonists (Emerging)

    5-HT3 antagonists are the dominant class within the postoperative nausea and vomiting market, renowned for their effectiveness and established safety in clinical settings. These agents work by blocking serotonin receptors, thereby preventing the onset of nausea and vomiting associated with surgical procedures and chemotherapy. Their longstanding presence in the market has led to widespread acceptance among healthcare professionals, contributing significantly to patient care. Conversely, dopamine antagonists represent an emerging segment characterized by their growing clinical utilization, particularly in cases where traditional therapies fall short. With an increasing number of surgical procedures, the demand for these medications is rapidly increasing. They are recognized for their multifaceted action, targeting different pathways involved in emesis, thus offering a complementary therapeutic approach to 5-HT3 antagonists.

    By Administration Route: Oral (Largest) vs. Intravenous (Fastest-Growing)

    In the postoperative nausea and vomiting market, the administration route segment shows a clear distribution among various values, with Oral administration leading as the largest segment. This method is favored for its ease of use and patient compliance, contributing significantly to its market share. Following Oral, Intravenous administration is gaining traction due to its rapid onset of action and effectiveness in managing severe nausea in postoperative patients.

    Intravenous: Dominant vs. Rectal: Emerging

    The intravenous route stands out as the dominant method for delivering antiemetic therapy in the postoperative care setting. Its ability to provide immediate relief makes it a preferred choice among healthcare providers, especially in acute scenarios. Conversely, the rectal route is emerging as an alternative option, particularly for patients who may have difficulty swallowing or for those who prefer not to use intravenous lines. As awareness of patient comfort increases, the rectal route may carve out a more significant niche in the market, appealing to specific patient populations and potentially seeing increased adoption.

    By Patient Demographics: Adult Patients (Largest) vs. Pediatric Patients (Fastest-Growing)

    In the Postoperative Nausea and Vomiting Market, the adult patient demographic holds the largest share, significantly outpacing both pediatric and geriatric patients. This is primarily due to the higher prevalence of surgical procedures among adults, led by various health conditions requiring surgical interventions. These adult patients constitute a substantial portion of postoperative care, with effective management of nausea and vomiting being essential for recovery and hospital discharge rates. Conversely, the pediatric demographic is emerging as the fastest-growing segment. This growth is attributed to an increase in pediatric surgeries and advancements in anesthetic practices that cater specifically to younger patients. Enhanced awareness surrounding the risks of postoperative nausea and vomiting in children reinforces the development of tailored therapies, further driving the segment’s expansion.

    Adult Patients (Dominant) vs. Geriatric Patients (Emerging)

    The adult patient segment is the dominant force in the postoperative nausea and vomiting management landscape, characterized by a well-established treatment regimen that leverages a variety of antiemetics tailored for efficacy in this age group. With a higher incidence of complicated surgeries in middle-aged and older adults, there is an ongoing demand for effective nausea management solutions. On the other hand, the geriatric patient segment, while smaller, is emerging with significant potential due to the rising number of older adults undergoing surgery. This demographic is increasingly recognized for its unique challenges, prompting further innovations focused on addressing their specific needs, thus paving the way for growth as tailored therapeutic strategies continue to evolve.

    Get more detailed insights about Postoperative Nausea Vomiting Market

    Regional Insights

    The Global Postoperative Nausea and Vomiting Market revenue is projected to achieve notable growth across regional segments, with North America dominating the market due to its substantial valuation of 1.75 USD Billion in 2024, expected to rise to 2.75 USD Billion in 2035. Europe follows, holding a significant position valued at 1.00 USD Billion in 2024 and anticipated to reach 1.50 USD Billion by 2035. The APAC region exhibits a growing opportunity, starting at 1.10 USD Billion in 2024 and expanding to 1.70 USD Billion in 2035.

    South America and MEA are smaller segments, valued at 0.25 USD Billion and 0.15 USD Billion in 2024, respectively, with steady growth projected to 0.40 USD Billion and 0.20 USD Billion by 2035.The diversity in regional growth figures reflects varying healthcare advancements, regulatory environments, and patient population needs, with North America's majority holding demonstrating robust demand for effective postoperative treatments. Against rising awareness and healthcare investment, the growth drivers and market trends are shaping the landscape of the Global Postoperative Nausea and Vomiting Market statistics, underscoring the need for tailored solutions across different regions.

    Postoperative Nausea And Vomiting Market Region

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Global Postoperative Nausea and Vomiting Market is characterized by a dynamic landscape driven by the increasing prevalence of surgical procedures and the consequent demand for effective management solutions for postoperative nausea and vomiting. As healthcare providers emphasize patient safety and recovery, companies within this market are focusing on innovative drug formulations, delivery methods, and a better understanding of patient needs. The competitive environment is marked by several key players striving to improve their product offerings, enhance clinical efficacy, and expand their market reach through strategic collaborations, mergers, and acquisitions.

    The presence of generic alternatives alongside branded pharmaceuticals is further shaping pricing strategies and market dynamics, making it a critical area for continuous research and development.Mylan has established a significant presence in the Global Postoperative Nausea and Vomiting Market with its commitment to providing high-quality and affordable treatment options. 

    The company is known for its extensive portfolio, which includes various formulations aimed at effectively addressing postoperative nausea and vomiting. Mylan's strengths lie in its robust supply chain capabilities and the ability to swiftly respond to market demands with the introduction of generic alternatives that are both cost-effective and accessible to a broader patient population. This agility positions Mylan favorably within the competitive market landscape, allowing it to cater to the needs of healthcare providers while maintaining a strong focus on patient outcomes.

    Mylan’s dedication to research and development also enhances its competitive edge as it continues to explore new therapeutic approaches and partnerships to expand its offerings within this segment.Amgen plays a crucial role in the Global Postoperative Nausea and Vomiting Market by leveraging its extensive research capabilities and innovative treatment modalities. 

    The company is recognized for its pioneering efforts in biopharmaceuticals, which enhance the management of postoperative complications, including nausea and vomiting. Amgen's strengths include its strong pipeline of products that target these specific conditions through advanced mechanisms of action. The company also engages in extensive clinical trials aimed at validating its therapeutic options, thereby reinforcing its reputation for delivering products that are not only effective but also safe for patients undergoing surgical procedures.

    Furthermore, Amgen's commitment to patient education and support reinforces its market positioning, as it strives to improve overall patient experiences and outcomes in postoperative settings, making it a significant player in this competitive landscape.

    Key Companies in the Postoperative Nausea Vomiting Market market include

    Industry Developments

    • Q2 2024: FDA Approves Acacia Pharma’s BARHEMSYS® (amisulpride injection) for the Prevention and Treatment of Postoperative Nausea and Vomiting in Adults The FDA granted approval to Acacia Pharma’s BARHEMSYS® (amisulpride injection) for use in adults to prevent and treat postoperative nausea and vomiting (PONV), expanding therapeutic options for surgical patients.
    • Q1 2024: Acacia Pharma Announces U.S. Commercial Launch of BARHEMSYS® (amisulpride injection) for Postoperative Nausea and Vomiting Acacia Pharma announced the commercial launch of BARHEMSYS® in the United States, making the newly approved antiemetic available to hospitals and surgical centers for the management of PONV.
    • Q2 2024: FDA Approves Heron Therapeutics’ ZYNRELEF® for Expanded Indication Including Postoperative Nausea and Vomiting Heron Therapeutics received FDA approval for an expanded indication of ZYNRELEF®, now including the management of postoperative nausea and vomiting in addition to pain control.
    • Q1 2024: Heron Therapeutics Announces U.S. Launch of ZYNRELEF® for Postoperative Nausea and Vomiting Heron Therapeutics launched ZYNRELEF® in the U.S. market for the management of postoperative nausea and vomiting, following its recent FDA approval for this indication.
    • Q2 2024: Acacia Pharma and Hikma Pharmaceuticals Enter U.S. Co-Promotion Agreement for BARHEMSYS® Acacia Pharma and Hikma Pharmaceuticals announced a co-promotion agreement to expand the reach of BARHEMSYS® for postoperative nausea and vomiting in the U.S. hospital market.
    • Q1 2024: Acacia Pharma acquired by Eagle Pharmaceuticals in $103 million deal Eagle Pharmaceuticals completed the acquisition of Acacia Pharma, gaining rights to BARHEMSYS® and BYFAVO®, both used in the management of postoperative symptoms including nausea and vomiting.
    • Q2 2024: Fresenius Kabi Launches Ondansetron Injection USP in the United States Fresenius Kabi announced the U.S. launch of its generic Ondansetron Injection USP, an antiemetic indicated for the prevention of postoperative nausea and vomiting.
    • Q1 2024: GSK Receives European Commission Approval for IV Granisetron for Postoperative Nausea and Vomiting GlaxoSmithKline received European Commission approval for its intravenous granisetron formulation, expanding its use for the prevention and treatment of postoperative nausea and vomiting in adult and pediatric patients.
    • Q2 2024: Dr. Reddy’s Laboratories Launches Generic Granisetron Injection in the U.S. Market Dr. Reddy’s Laboratories announced the launch of its generic granisetron injection in the United States, indicated for the prevention of postoperative nausea and vomiting.
    • Q1 2024: Pfizer Launches New Formulation of ALOXI® (palonosetron hydrochloride) Injection for Postoperative Nausea and Vomiting Pfizer announced the launch of a new formulation of ALOXI® injection, designed for the prevention of postoperative nausea and vomiting in adult patients.
    • Q2 2024: Eagle Pharmaceuticals receives FDA approval for new BYFAVO® formulation for procedural sedation and PONV Eagle Pharmaceuticals received FDA approval for a new formulation of BYFAVO®, which is indicated for procedural sedation and the management of postoperative nausea and vomiting.
    • Q1 2024: Sandoz Launches Generic Dexamethasone Injection for Postoperative Nausea and Vomiting in the U.S. Sandoz announced the launch of its generic dexamethasone injection in the United States, indicated for the prevention and treatment of postoperative nausea and vomiting.

    Future Outlook

    Postoperative Nausea Vomiting Market Future Outlook

    The Postoperative Nausea and Vomiting Market is projected to grow at a 3.94% CAGR from 2024 to 2035, driven by advancements in antiemetic therapies and increasing surgical procedures.

    New opportunities lie in:

    • Development of personalized antiemetic regimens for high-risk patients.
    • Integration of digital health solutions for real-time monitoring.
    • Expansion of outpatient services to enhance patient recovery experiences.

    By 2035, the market is expected to demonstrate robust growth and innovation.

    Market Segmentation

    Postoperative Nausea Vomiting Market Medication Class Outlook

    • 5-HT3 Antagonists
    • Dopamine Antagonists
    • Antihistamines
    • Corticosteroids

    Postoperative Nausea Vomiting Market Type of Treatment Outlook

    • Pharmacological Treatment
    • Non-Pharmacological Treatment
    • Combination Therapy

    Postoperative Nausea Vomiting Market Administration Route Outlook

    • Oral
    • Intravenous
    • Rectal

    Postoperative Nausea Vomiting Market Patient Demographics Outlook

    • Pediatric Patients
    • Adult Patients
    • Geriatric Patients

    Report Scope

    MARKET SIZE 20244.251(USD Billion)
    MARKET SIZE 20254.419(USD Billion)
    MARKET SIZE 20356.503(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR)3.94% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Billion
    Key Companies ProfiledMarket analysis in progress
    Segments CoveredMarket segmentation analysis in progress
    Key Market OpportunitiesAdvancements in antiemetic therapies enhance patient outcomes in the Postoperative Nausea and Vomiting Market.
    Key Market DynamicsRising demand for effective antiemetic therapies drives innovation and competition in the postoperative nausea and vomiting market.
    Countries CoveredNorth America, Europe, APAC, South America, MEA

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    FAQs

    What is the expected market size of the Global Postoperative Nausea and Vomiting Market in 2024?

    The Global Postoperative Nausea and Vomiting Market is expected to be valued at 4.25 billion USD in 2024.

    What will be the market size of the Global Postoperative Nausea and Vomiting Market by 2035?

    By 2035, the market size is projected to reach 6.5 billion USD.

    What is the expected compound annual growth rate (CAGR) for the Global Postoperative Nausea and Vomiting Market from 2025 to 2035?

    The expected CAGR for the market from 2025 to 2035 is 3.94%.

    Which region is expected to dominate the Global Postoperative Nausea and Vomiting Market by 2024?

    North America is expected to hold the largest share of the market, valued at 1.75 billion USD in 2024.

    How much is the market for Pharmacological Treatment projected to grow by 2035?

    The market for Pharmacological Treatment is projected to grow from 2.1 billion USD in 2024 to 3.2 billion USD by 2035.

    What will be the market size for Non-Pharmacological Treatment by 2035?

    The market size for Non-Pharmacological Treatment is expected to reach 1.7 billion USD by 2035.

    Which companies are considered major players in the Global Postoperative Nausea and Vomiting Market?

    Major players include Mylan, Johnson and Johnson, Pfizer, and Merck.

    What is the expected market value of Combination Therapy in 2035?

    The market value for Combination Therapy is expected to increase to 1.6 billion USD by 2035.

    What is the market size for the Asia-Pacific region in 2024?

    The Asia-Pacific region's market size is expected to be 1.1 billion USD in 2024.

    What are the market growth expectations for the South America region by 2035?

    By 2035, the South American market size is projected to grow to 0.4 billion USD.

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