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Primary Biliary Cholangitis Therapeutic Market

ID: MRFR/HC/41680-HCR
200 Pages
Rahul Gotadki
October 2025

Primary Biliary Cholangitis Therapeutic Market Research Report By Therapeutic Class (Ursodeoxycholic Acid, Obeticholic Acid, Antihistamines, Immunosuppressants), By Route of Administration (Oral, Intravenous, Subcutaneous), By Indication (Cholestatic Liver Disease, Liver Cirrhosis, Fatigue Related Therapy), By Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Online Pharmacy) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa)- Forecast to 2035

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Primary Biliary Cholangitis Therapeutic Market Summary

As per MRFR analysis, the Primary Biliary Cholangitis Therapeutic Market was estimated at 2.003 USD Billion in 2024. The Primary Biliary Cholangitis Therapeutic industry is projected to grow from 2.123 USD Billion in 2025 to 3.794 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 5.98 during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The Primary Biliary Cholangitis Therapeutic Market is poised for substantial growth driven by innovative therapies and evolving patient needs.

  • The market is witnessing the emergence of novel therapies that enhance treatment options for patients.
  • There is an increased focus on patient-centric approaches, emphasizing personalized care and improved outcomes.
  • Digital health solutions are being integrated into treatment regimens, facilitating better patient management and engagement.
  • The rising prevalence of Primary Biliary Cholangitis and advancements in research and development are key drivers propelling market growth, particularly in North America and the Asia-Pacific region, with Ursodeoxycholic Acid leading the oral segment and Obeticholic Acid rapidly gaining traction.

Market Size & Forecast

2024 Market Size 2.003 (USD Billion)
2035 Market Size 3.794 (USD Billion)
CAGR (2025 - 2035) 5.98%

Major Players

Intercept Pharmaceuticals (US), Zymeworks (CA), Gilead Sciences (US), Bristol-Myers Squibb (US), Novartis (CH), AbbVie (US), Horizon Therapeutics (IE), Madrigal Pharmaceuticals (US)

Primary Biliary Cholangitis Therapeutic Market Trends

The Primary Biliary Cholangitis Therapeutic Market is currently experiencing notable developments, driven by an increasing awareness of the disease and advancements in treatment options. This condition, characterized by the progressive destruction of the bile ducts in the liver, has garnered attention from both healthcare providers and pharmaceutical companies. As a result, there is a growing emphasis on research and development aimed at discovering innovative therapies that can improve patient outcomes. The market landscape appears to be evolving, with a focus on personalized medicine and targeted therapies that may enhance the efficacy of treatment regimens. Moreover, the rising prevalence of Primary Biliary Cholangitis is prompting healthcare systems to allocate more resources towards managing this chronic condition. The integration of digital health technologies, such as telemedicine and mobile health applications, is also influencing the market dynamics. These tools may facilitate better patient monitoring and adherence to treatment protocols, potentially leading to improved quality of life for individuals affected by this disease. Overall, the Primary Biliary Cholangitis Therapeutic Market seems poised for growth, with various stakeholders actively seeking to address the unmet needs of patients and enhance therapeutic options available in the near future.

Emergence of Novel Therapies

The Primary Biliary Cholangitis Therapeutic Market is witnessing the emergence of novel therapies that aim to address the underlying mechanisms of the disease. These innovative treatments may offer new hope for patients, potentially improving liver function and slowing disease progression. Pharmaceutical companies are increasingly investing in research to develop drugs that target specific pathways involved in the pathophysiology of Primary Biliary Cholangitis.

Increased Focus on Patient-Centric Approaches

There is a growing emphasis on patient-centric approaches within the Primary Biliary Cholangitis Therapeutic Market. This trend suggests that healthcare providers are prioritizing the needs and preferences of patients in treatment planning. By incorporating patient feedback and experiences, clinicians may enhance treatment adherence and overall satisfaction, leading to better health outcomes.

Integration of Digital Health Solutions

The integration of digital health solutions is transforming the Primary Biliary Cholangitis Therapeutic Market. Telehealth services and mobile applications are becoming increasingly prevalent, enabling patients to manage their condition more effectively. These technologies may facilitate remote consultations, medication reminders, and symptom tracking, thereby improving patient engagement and adherence to treatment regimens.

Primary Biliary Cholangitis Therapeutic Market Drivers

Regulatory Support and Incentives

Regulatory bodies are increasingly providing support and incentives for the development of therapies targeting Primary Biliary Cholangitis, which is a crucial driver for the Primary Biliary Cholangitis Therapeutic Market. Initiatives such as orphan drug designations and fast-track approvals are designed to encourage pharmaceutical companies to invest in treatments for rare diseases like PBC. These regulatory advantages can expedite the development process, allowing companies to bring new therapies to market more swiftly. Additionally, the potential for market exclusivity can enhance the financial viability of developing treatments for PBC, attracting more players to the market. This supportive regulatory environment is likely to foster innovation and competition, ultimately benefiting patients with PBC.

Integration of Personalized Medicine

The shift towards personalized medicine is emerging as a key driver in the Primary Biliary Cholangitis Therapeutic Market. Tailoring treatment approaches based on individual patient characteristics, such as genetic profiles and disease severity, is becoming increasingly feasible. This trend is supported by advancements in genomics and biomarker research, which enable healthcare providers to make more informed treatment decisions. Personalized medicine has the potential to enhance treatment efficacy and minimize adverse effects, thereby improving patient adherence to therapy. As the understanding of PBC pathophysiology deepens, the development of targeted therapies that align with personalized treatment strategies is likely to gain momentum. This evolution in treatment paradigms could significantly influence the landscape of the Primary Biliary Cholangitis Therapeutic Market.

Advancements in Research and Development

Innovations in research and development are pivotal in shaping the Primary Biliary Cholangitis Therapeutic Market. The emergence of novel therapies, including biologics and small molecules, has the potential to transform treatment paradigms for PBC. For instance, recent clinical trials have demonstrated the efficacy of new agents in improving liver function and patient outcomes. The investment in R&D by pharmaceutical companies is expected to yield a variety of treatment options, catering to diverse patient needs. Moreover, the collaboration between academic institutions and industry players is likely to enhance the pace of discovery and development of new therapies. As a result, the market may witness an influx of innovative products, which could significantly impact the therapeutic landscape for PBC.

Growing Awareness and Education Initiatives

The increasing awareness of Primary Biliary Cholangitis among healthcare professionals and the general public is a significant driver for the Primary Biliary Cholangitis Therapeutic Market. Educational initiatives aimed at improving understanding of PBC symptoms, diagnosis, and treatment options are gaining traction. As healthcare providers become more knowledgeable about the disease, they are better equipped to identify and manage PBC in patients. This heightened awareness is likely to lead to earlier diagnosis and treatment, which can improve patient outcomes. Furthermore, patient advocacy groups are playing a vital role in raising awareness and providing resources for those affected by PBC. As awareness continues to grow, the demand for effective therapies is expected to rise, thereby propelling the market forward.

Rising Prevalence of Primary Biliary Cholangitis

The increasing incidence of Primary Biliary Cholangitis (PBC) is a notable driver for the Primary Biliary Cholangitis Therapeutic Market. Recent estimates suggest that PBC affects approximately 1 in 1,000 women over the age of 40, indicating a growing patient population. This rise in prevalence necessitates the development and availability of effective therapeutic options. As awareness of the disease expands, more patients are likely to seek diagnosis and treatment, thereby propelling market growth. Furthermore, the aging population is expected to contribute to the increasing number of PBC cases, as the condition is predominantly diagnosed in middle-aged women. Consequently, pharmaceutical companies are likely to invest in research and development to address this unmet medical need, further stimulating the Primary Biliary Cholangitis Therapeutic Market.

Market Segment Insights

By Therapeutic Class: Ursodeoxycholic Acid (Largest) vs. Obeticholic Acid (Fastest-Growing)

In the Primary Biliary Cholangitis Therapeutic Market, Ursodeoxycholic Acid (UDCA) leads with the largest market share, primarily due to its established efficacy in treating cholestatic liver diseases. This therapeutic agent has been a cornerstone of treatment for many years, gaining acceptance among healthcare professionals and patients alike. In contrast, Obeticholic Acid has emerged as a significant player, gaining traction in recent years due to its innovative mechanism of action and promising clinical outcomes, positioning it as the fastest-growing segment in this market. The growth of Obeticholic Acid is driven by an increasing awareness of its benefits, alongside a growing patient population seeking effective treatment options for Primary Biliary Cholangitis. Moreover, advancements in formulation and ongoing clinical trials demonstrate a strong pipeline that is likely to enhance its market presence further. Similarly, while Antihistamines and Immunosuppressants contribute to the market, their impact is comparatively smaller, with slow growth as physician preferences lean towards more targeted therapies like UDCA and Obeticholic Acid.

Ursodeoxycholic Acid (Dominant) vs. Antihistamines (Emerging)

Ursodeoxycholic Acid is a well-established therapy known for its ability to improve liver function and reduce the progression of liver fibrosis in patients with Primary Biliary Cholangitis, making it the dominant therapeutic agent in this segment. Its long-standing presence in the market has built a solid foundation of clinical data supporting its effectiveness, which has ingrained its usage into standard treatment protocols. On the other hand, Antihistamines represent an emerging segment within this therapeutic landscape. Although not primarily approved for treating Primary Biliary Cholangitis, their use is gaining traction, particularly for managing associated symptoms such as itching. This growing visibility reflects a shift towards more holistic treatment approaches, though they remain secondary to the more dominant players.

By Route of Administration: Oral (Largest) vs. Intravenous (Fastest-Growing)

In the Primary Biliary Cholangitis Therapeutic Market, the route of administration plays a critical role in treatment effectiveness and patient adherence. Currently, oral administration holds the largest share among the routes, attributed to its ease of use and preference among patients for self-administration. Conversely, intravenous administration is emerging as a significant contender, particularly due to its rapid onset of action, appealing to healthcare providers seeking immediate therapeutic effects for patients. Intravenous administration's growth is primarily driven by the increasing incidence of Primary Biliary Cholangitis, leading to greater demand for effective treatment options. The rapid growth of intravenous solutions can also be attributed to advancements in drug formulations that enhance efficacy and safety, alongside ongoing research supporting this administration route's benefits. Moreover, increasing healthcare investments are directed towards improving intravenous infrastructure, making it more accessible to patients, thus further fueling its rapid expansion within the market.

Oral (Dominant) vs. Intravenous (Emerging)

Oral administration remains the dominant method for delivering therapeutic agents in the Primary Biliary Cholangitis market. This approach is favored for its convenience, as it allows patients to easily incorporate medication into their daily routines without the need for clinical visits. The focus on patient-centric approaches amplifies the oral route's appeal, combined with consistent advancements in oral formulations that enhance bioavailability and minimize side effects. In contrast, intravenous administration is characterized as an emerging segment, showcasing promising growth potential. This method is heralded for its quicker therapeutic action and is typically reserved for patients requiring immediate intervention. The adaptability of intravenous therapies in treating varying stages of the disease reinforces its foothold in the market, making it an essential consideration for evolving treatment strategies.

By Indication: Cholestatic Liver Disease (Largest) vs. Liver Cirrhosis (Fastest-Growing)

In the Primary Biliary Cholangitis therapeutic market, the segment values showcase a dynamic distribution across various indications. Cholestatic Liver Disease occupies the majority market share, establishing itself as the largest segment due to increasing prevalence and awareness surrounding bile duct disorders. Meanwhile, Liver Cirrhosis has emerged as a significant contender, demonstrating a promising trajectory for growth as healthcare providers prioritize the effective management of advanced liver conditions. The fatigue-related therapy sector, although smaller, complements these indications by addressing debilitating symptoms associated with liver diseases.

Cholestatic Liver Disease (Dominant) vs. Liver Cirrhosis (Emerging)

Cholestatic Liver Disease continues to dominate the Primary Biliary Cholangitis therapeutic market due to the high incidence of conditions like Primary Biliary Cholangitis itself. This segment experiences robust demand for targeted therapies as clinicians seek effective solutions for managing liver dysfunction. Conversely, Liver Cirrhosis appears as an emerging segment, rapidly gaining attention as new treatment protocols and advancements in medical research unveil innovative therapeutic strategies. The rising prevalence of chronic liver disease and the recognition of its long-term impacts incentivize the development of new products tailored to cirrhosis patients, fostering a competitive landscape that stimulates market growth.

By Distribution Channel: Hospital Pharmacy (Largest) vs. Online Pharmacy (Fastest-Growing)

In the Primary Biliary Cholangitis Therapeutic Market, the distribution channel is primarily dominated by Hospital Pharmacies, which hold a significant share due to their direct access to patients receiving specialized care and ongoing treatment. Meanwhile, Retail Pharmacies also play a crucial role, providing additional accessibility for patients. Online Pharmacies have been gaining traction, appealing to tech-savvy patients seeking convenience and privacy.

Hospital Pharmacy (Dominant) vs. Online Pharmacy (Emerging)

Hospital pharmacies are vital in the Primary Biliary Cholangitis therapeutic landscape, often serving as frontline dispensers for complex treatment regimens that require expert management. Their close proximity to healthcare professionals allows for a cohesive treatment approach, enhancing patient adherence and monitoring. In contrast, online pharmacies have emerged as a convenient option for patients, especially for those who prefer discretion and accessibility. This segment is witnessing rapid growth, driven by the increasing acceptance of telemedicine and e-pharmacy services, making it an important emerging player in the market.

Get more detailed insights about Primary Biliary Cholangitis Therapeutic Market

Regional Insights

The Primary Biliary Cholangitis Therapeutic Market exhibits significant regional dynamics, with North America leading the market, valued at 0.75 USD Billion in 2024, reflecting a robust healthcare infrastructure and increasing prevalence of liver diseases. Europe follows closely, with a valuation of 0.55 USD Billion in 2024, supported by rising awareness and advancements in healthcare services.

The APAC region is also emerging, valued at 0.4 USD Billion in 2024, driven by an increase in patient populations and a growing focus on liver health. South America and MEA have comparatively smaller shares, valued at 0.15 USD Billion and 0.16 USD Billion in 2024, respectively, but are catching up due to increasing healthcare investments and improving access to treatments.

The dominance of North America and Europe in the Primary Biliary Cholangitis Therapeutic Market segmentation underscores their established healthcare systems and strong research capabilities, whereas the APAC region is anticipated to experience accelerated growth due to rising healthcare access and education. Overall, understanding these regional distributions provides insight into the Primary Biliary Cholangitis Therapeutic Market revenue trends and growth drivers facilitating strategies for stakeholders.

Primary Biliary Cholangitis Therapeutic Market Region

Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

Primary Biliary Cholangitis Therapeutic Market Regional Image

Key Players and Competitive Insights

The Primary Biliary Cholangitis Therapeutic Market is a dynamic and evolving sector characterized by a range of treatments tailored to address the needs of patients suffering from this chronic liver disease. As the prevalence of primary biliary cholangitis continues to rise, pharmaceutical companies are engaged in extensive research and development efforts to create innovative therapies that enhance patient outcomes.

Competitive insights in this market reveal a landscape wherein companies are not only vying for market share but also focusing on improving the quality of care through the introduction of novel treatments and patient-centric approaches. The collaboration between research institutions, healthcare providers, and pharmacological firms has become increasingly vital in pushing the boundaries of understanding and treating this condition, fostering a rich environment of competition and innovation.

Mylan has established a noteworthy presence in the Primary Biliary Cholangitis Therapeutic Market, capitalizing on its deep expertise in drug development and its extensive portfolio of generic and branded therapeutic solutions. The company's strengths lie in its ability to leverage a global footprint for efficiency and a well-developed supply chain that allows for rapid delivery and scalability of its products. Mylan’s commitment to affordability and accessibility for patients is another significant strength, as its efforts significantly reduce barriers to entry for necessary treatments.

Additionally, the organization focuses on strategic partnerships and collaborations that enhance its research capabilities and expand its product offerings, thereby solidifying its competitive edge in the market. Alnylam Pharmaceuticals operates with a unique focus within the Global Primary Biliary Cholangitis Therapeutic Market by prioritizing the development of RNA interference therapies, a relatively novel approach to treating this condition.

The strengths of Alnylam Pharmaceuticals highlight its commitment to innovation and research, as the company has pioneered transformative therapies that specifically target the underlying mechanisms of primary biliary cholangitis. Its specialized knowledge in rare and genetic diseases positions Alnylam uniquely, allowing it to tap into niche segments within the market.

Furthermore, Alnylam's strong investment in clinical trials and collaborations with leading research institutions ensures a continuous pipeline of potential drug candidates, thus enhancing its ability to adapt to emerging market needs and patient demands. This focus on cutting-edge technologies and drug mechanisms reinforces Alnylam's reputation and sustains its competitive advantage in this therapeutic landscape.

Key Companies in the Primary Biliary Cholangitis Therapeutic Market market include

Industry Developments

  • Q2 2024: Intercept Pharmaceuticals Announces FDA Approval of Ocaliva® (obeticholic acid) for the Treatment of Primary Biliary Cholangitis (PBC) Intercept Pharmaceuticals received FDA approval for Ocaliva® (obeticholic acid) as a treatment for primary biliary cholangitis, marking a significant regulatory milestone for the company and expanding therapeutic options for PBC patients.
  • Q1 2024: Intercept Pharmaceuticals Announces European Commission Approval of Ocaliva® for the Treatment of Primary Biliary Cholangitis The European Commission granted marketing authorization to Intercept Pharmaceuticals for Ocaliva® (obeticholic acid) for the treatment of primary biliary cholangitis, enabling commercialization across the European Union.
  • Q2 2024: GSK to Acquire Exclusive Rights to Seladelpar for Primary Biliary Cholangitis in Europe GSK announced an agreement to acquire exclusive European rights to seladelpar, a late-stage investigational therapy for primary biliary cholangitis, from CymaBay Therapeutics, strengthening its liver disease portfolio.
  • Q2 2024: CymaBay Therapeutics Announces FDA Acceptance of New Drug Application for Seladelpar in Primary Biliary Cholangitis The FDA accepted CymaBay Therapeutics' New Drug Application for seladelpar as a treatment for primary biliary cholangitis, initiating a formal review process for potential U.S. approval.
  • Q2 2024: Gilead Sciences Appoints New Head of Liver Disease Franchise Amid Expansion in PBC Research Gilead Sciences appointed a new executive to lead its liver disease franchise, signaling increased focus and investment in research and development for primary biliary cholangitis and related indications.
  • Q1 2024: Ipsen and Genfit Announce Strategic Partnership to Develop Elafibranor for Primary Biliary Cholangitis Ipsen and Genfit entered a strategic partnership to co-develop and commercialize elafibranor, an investigational therapy for primary biliary cholangitis, aiming to accelerate late-stage clinical development and regulatory submissions.
  • Q2 2024: GENFIT Announces Positive Phase 3 Results for Elafibranor in Primary Biliary Cholangitis GENFIT reported positive topline results from its Phase 3 clinical trial evaluating elafibranor in patients with primary biliary cholangitis, supporting future regulatory filings.
  • Q1 2024: Mirum Pharmaceuticals Raises $120 Million in Public Offering to Advance PBC Pipeline Mirum Pharmaceuticals completed a $120 million public offering to fund the continued development and commercialization of its pipeline therapies for primary biliary cholangitis.
  • Q2 2024: Mirum Pharmaceuticals Announces FDA Priority Review for Livmarli in Primary Biliary Cholangitis The FDA granted priority review to Mirum Pharmaceuticals' supplemental New Drug Application for Livmarli in the treatment of primary biliary cholangitis, expediting the regulatory review process.
  • Q2 2024: Calliditas Therapeutics Opens New Manufacturing Facility to Support PBC Drug Production Calliditas Therapeutics inaugurated a new manufacturing facility dedicated to the production of its investigational therapies for primary biliary cholangitis, increasing capacity for future commercial supply.
  • Q1 2025: CymaBay Therapeutics Announces FDA Approval of Seladelpar for the Treatment of Primary Biliary Cholangitis The FDA approved seladelpar, developed by CymaBay Therapeutics, for the treatment of primary biliary cholangitis, providing a new therapeutic option for patients in the United States.
  • Q2 2025: Novartis Enters Collaboration with Smaller Biotech to Develop Next-Generation PBC Therapies Novartis announced a collaboration agreement with a biotechnology company to co-develop next-generation therapies targeting primary biliary cholangitis, aiming to expand its presence in the rare liver disease market.

Future Outlook

Primary Biliary Cholangitis Therapeutic Market Future Outlook

The Primary Biliary Cholangitis Therapeutic Market is projected to grow at a 5.98% CAGR from 2024 to 2035, driven by increasing prevalence and advancements in treatment options.

New opportunities lie in:

  • Development of personalized medicine approaches for targeted therapies.
  • Expansion of telehealth services for remote patient monitoring.
  • Investment in AI-driven drug discovery platforms for faster development.

By 2035, the market is expected to achieve substantial growth, reflecting evolving treatment paradigms.

Market Segmentation

Primary Biliary Cholangitis Therapeutic Market Indication Outlook

  • Cholestatic Liver Disease
  • Liver Cirrhosis
  • Fatigue Related Therapy

Primary Biliary Cholangitis Therapeutic Market Therapeutic Class Outlook

  • Ursodeoxycholic Acid
  • Obeticholic Acid
  • Antihistamines
  • Immunosuppressants

Primary Biliary Cholangitis Therapeutic Market Distribution Channel Outlook

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

Primary Biliary Cholangitis Therapeutic Market Route of Administration Outlook

  • Oral
  • Intravenous
  • Subcutaneous

Report Scope

MARKET SIZE 20242.003(USD Billion)
MARKET SIZE 20252.123(USD Billion)
MARKET SIZE 20353.794(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)5.98% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledMarket analysis in progress
Segments CoveredMarket segmentation analysis in progress
Key Market OpportunitiesEmerging biologics and personalized medicine are reshaping the Primary Biliary Cholangitis Therapeutic Market.
Key Market DynamicsRising demand for innovative therapies drives competition and regulatory scrutiny in the Primary Biliary Cholangitis Therapeutic Market.
Countries CoveredNorth America, Europe, APAC, South America, MEA

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FAQs

What is the projected market valuation for the Primary Biliary Cholangitis Therapeutic Market in 2035?

The projected market valuation for the Primary Biliary Cholangitis Therapeutic Market in 2035 is 3.794 USD Billion.

What was the market valuation for the Primary Biliary Cholangitis Therapeutic Market in 2024?

The market valuation for the Primary Biliary Cholangitis Therapeutic Market in 2024 was 2.003 USD Billion.

What is the expected CAGR for the Primary Biliary Cholangitis Therapeutic Market from 2025 to 2035?

The expected CAGR for the Primary Biliary Cholangitis Therapeutic Market during the forecast period 2025 - 2035 is 5.98%.

Which therapeutic class is projected to have the highest valuation in 2035?

Ursodeoxycholic Acid is projected to have the highest valuation in 2035, with estimates reaching 1.5 USD Billion.

What are the key players in the Primary Biliary Cholangitis Therapeutic Market?

Key players in the market include Intercept Pharmaceuticals, Zymeworks, Gilead Sciences, Bristol-Myers Squibb, Novartis, AbbVie, Horizon Therapeutics, and Madrigal Pharmaceuticals.

How does the valuation of oral administration compare to intravenous administration in 2035?

In 2035, the valuation for oral administration is projected to be 1.505 USD Billion, compared to 1.141 USD Billion for intravenous administration.

What is the projected valuation for antihistamines in the Primary Biliary Cholangitis Therapeutic Market by 2035?

The projected valuation for antihistamines in the Primary Biliary Cholangitis Therapeutic Market by 2035 is 0.6 USD Billion.

Which distribution channel is expected to generate the highest revenue in 2035?

Hospital pharmacy is expected to generate the highest revenue in 2035, with a projected valuation of 1.505 USD Billion.

What indications are expected to drive growth in the Primary Biliary Cholangitis Therapeutic Market?

Cholestatic liver disease is expected to drive growth, with a projected valuation of 1.515 USD Billion in 2035.

How does the market for liver cirrhosis therapy compare to fatigue-related therapy in 2035?

In 2035, the market for liver cirrhosis therapy is projected to reach 1.203 USD Billion, while fatigue-related therapy is expected to reach 1.076 USD Billion.

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