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South America Drug Repurposing Market

ID: MRFR/Pharma/50635-HCR
200 Pages
Rahul Gotadki
October 2025

South America Drug Repurposing Market Research Report By Types (Disease-centric, Target-centric, Drug-centric), By Therapeutic Area (Same Therapeutic Area, Different Therapeutic Area), By Drug Molecules (Biologics, Small Molecule) and By Regional (Brazil, Mexico, Argentina, Rest of South America) - Forecast to 2035

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South America Drug Repurposing Market Infographic
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South America Drug Repurposing Market Summary

As per MRFR analysis, the South America drug repurposing market size was estimated at 40.0 USD Million in 2024. The South America drug repurposing market is projected to grow from 46.0 USD Million in 2025 to 186.13 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 15.0% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America drug repurposing market is experiencing dynamic growth driven by collaborative efforts and regulatory support.

  • Increased collaboration among stakeholders is fostering innovation in the South America drug repurposing market.
  • Brazil remains the largest market, while Mexico is recognized as the fastest-growing region in this sector.
  • There is a notable focus on chronic disease management, reflecting the evolving healthcare landscape in South America.
  • Rising healthcare costs and the growing burden of non-communicable diseases are key drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 40.0 (USD Million)
2035 Market Size 186.13 (USD Million)

Major Players

Pfizer (US), Novartis (CH), Bristol-Myers Squibb (US), Johnson & Johnson (US), AstraZeneca (GB), Roche (CH), Eli Lilly and Company (US), GSK (GB), Sanofi (FR)

South America Drug Repurposing Market Trends

The drug repurposing market is experiencing notable growth in South America, driven by the increasing need for cost-effective therapeutic solutions. This region has witnessed a surge in interest from both public and private sectors, as stakeholders recognize the potential of existing drugs to treat various diseases. The collaboration between academic institutions and pharmaceutical companies is fostering innovation, leading to the identification of new applications for established medications. Furthermore, regulatory bodies are becoming more supportive of repurposing initiatives, streamlining approval processes to expedite access to treatments. In addition, the rising prevalence of chronic diseases in South America is prompting healthcare providers to explore alternative treatment options. The drug repurposing market appears to be a viable strategy to address unmet medical needs while minimizing development costs. As healthcare systems in the region evolve, there is a growing emphasis on personalized medicine, which aligns well with the principles of drug repurposing. This trend suggests a promising future for the market, as it adapts to the unique challenges and opportunities present in South America.

Increased Collaboration Among Stakeholders

The drug repurposing market is witnessing enhanced collaboration among various stakeholders, including academic institutions, pharmaceutical companies, and government agencies. This trend is fostering a more integrated approach to research and development, allowing for the sharing of resources and expertise. Such partnerships are likely to accelerate the identification of new therapeutic uses for existing drugs, ultimately benefiting patients in South America.

Regulatory Support for Repurposing Initiatives

Regulatory bodies in South America are increasingly recognizing the importance of drug repurposing as a means to address public health challenges. This support is manifesting in the form of streamlined approval processes and guidelines that facilitate the repurposing of existing medications. As a result, the drug repurposing market is expected to expand, providing quicker access to innovative treatments for various diseases.

Focus on Chronic Disease Management

The rising burden of chronic diseases in South America is driving interest in the drug repurposing market. Healthcare providers are actively seeking effective and affordable treatment options for conditions such as diabetes, hypertension, and cardiovascular diseases. By leveraging existing drugs, the market is positioned to offer solutions that meet the growing demand for effective chronic disease management.

South America Drug Repurposing Market Drivers

Rising Healthcare Costs

The escalating costs associated with healthcare in South America are driving interest in the drug repurposing market. As healthcare expenditures continue to rise, stakeholders are increasingly seeking cost-effective solutions to address various medical conditions. Drug repurposing offers a viable pathway to reduce development costs, as existing drugs can be utilized for new therapeutic indications. This approach not only shortens the time to market but also minimizes the financial burden on healthcare systems. In South America, where healthcare budgets are often constrained, the potential for repurposed drugs to provide affordable treatment options is particularly appealing. The drug repurposing market is thus positioned to benefit from this trend, as it aligns with the need for innovative yet economical healthcare solutions.

Advancements in Technology

Technological advancements are playing a pivotal role in shaping the drug repurposing market in South America. Innovations in data analytics, artificial intelligence, and bioinformatics are enhancing the ability to identify new therapeutic uses for existing drugs. These technologies facilitate the analysis of vast datasets, enabling researchers to uncover potential repurposing opportunities more efficiently. As a result, the drug repurposing market is experiencing a surge in interest from both public and private sectors. The integration of technology not only accelerates the research process but also improves the accuracy of predictions regarding drug efficacy for new indications, thereby fostering a more robust pipeline of repurposed drugs.

Regulatory Framework Enhancements

The evolving regulatory landscape in South America is positively impacting the drug repurposing market. Regulatory bodies are increasingly recognizing the value of repurposed drugs in expediting access to treatments. Streamlined approval processes and supportive policies are being implemented to facilitate the development and commercialization of repurposed medications. This regulatory support is crucial for the drug repurposing market, as it reduces barriers to entry and encourages investment in this area. By fostering a more favorable regulatory environment, authorities are likely to stimulate innovation and enhance the availability of effective therapies for patients in need.

Growing Burden of Non-Communicable Diseases

The rising prevalence of non-communicable diseases (NCDs) in South America is significantly influencing the drug repurposing market. Conditions such as diabetes, cardiovascular diseases, and cancer are becoming increasingly common, necessitating the development of effective treatment strategies. Drug repurposing presents an opportunity to quickly provide therapies for these diseases by leveraging existing medications. The World Health Organization has indicated that NCDs account for approximately 70% of all deaths in the region, underscoring the urgent need for innovative solutions. The drug repurposing market is likely to thrive as it addresses this growing health crisis, offering a faster and more cost-effective means to combat the rising tide of NCDs.

Increased Investment in Research and Development

Investment in research and development (R&D) is crucial for the growth of the drug repurposing market in South America. Governments and private entities are recognizing the potential of repurposed drugs to address unmet medical needs. As a result, funding for R&D initiatives is on the rise, with a focus on exploring new applications for existing medications. This influx of capital is likely to enhance the capabilities of research institutions and pharmaceutical companies, leading to a more dynamic drug repurposing market. The commitment to R&D not only fosters innovation but also encourages collaboration among stakeholders, further propelling the market forward.

Market Segment Insights

By Type: Disease-centric (Largest) vs. Target-centric (Fastest-Growing)

In the South America drug repurposing market, the Disease-centric approach holds the largest share, dominating the strategies employed in this sector. This strategy revolves around identifying drugs that can potentially treat various diseases, leveraging existing knowledge about their safety and efficacy. Target-centric strategies, while currently smaller in market share, are gaining traction as they focus on specific biological targets, offering specialized treatment options in a rapidly evolving landscape. Growth trends indicate that the Target-centric approach is emerging as the fastest-growing segment within the market, driven by advancements in biotechnology and precision medicine. Both approaches are influenced by increasing investment in research and development, coupled with a push towards personalized medicine. The shift in focus towards precision therapy provides robust opportunities for growth and innovation in the repurposing of drugs.

Disease-centric (Dominant) vs. Target-centric (Emerging)

The Disease-centric approach has established itself as the dominant force in the South America drug repurposing market due to its comprehensive focus on leveraging existing drugs to treat a wide range of diseases. This strategy capitalizes on the extensive data available for established medications, minimizing the risks associated with new drug development. On the other hand, the Target-centric approach is emerging as a critical player as it seeks to identify specific biological markers and targets for treatment. This method allows for tailored therapies and potentially higher response rates in patients, appealing to stakeholders interested in innovative healthcare solutions. Both strategies play significant roles, but their applications and implications for patient care differ markedly.

By Therapeutic Area: Same Therapeutic Area (Largest) vs. Different Therapeutic Area (Fastest-Growing)

In the therapeutic area segment, Same Therapeutic Area dominates the landscape, holding a substantial market share due to its established protocols and familiarity among healthcare providers. This segment benefits from existing drug formulations that are being repurposed to treat indications within the same therapeutic domain, ensuring a lower development risk and faster regulatory approvals. Conversely, Different Therapeutic Area is making significant inroads, rapidly expanding as innovative research unveils potential in repurposing existing drugs for entirely new conditions, thereby driving market growth. Growth trends indicate a robust increase in the adoption of repurposed drugs across both segments. The Same Therapeutic Area continues to thrive as pharmaceutical companies leverage previously successful drugs for new applications, propelled by the need for cost-effective solutions. Meanwhile, the Different Therapeutic Area segment is gaining momentum, propelled by advancements in biotechnology and a growing emphasis on personalized medicine. As scientific understanding deepens, the potential for repurposing drugs for different therapeutic areas is becoming increasingly viable, fostering a competitive environment for market players.

Same Therapeutic Area (Dominant) vs. Different Therapeutic Area (Emerging)

The Same Therapeutic Area segment remains a dominant force in the drug repurposing market, characterized by its strong reliance on existing medications to meet emerging patient needs. This segment benefits from lower risk profiles, as the efficacy and safety of these drugs are often well-established. Healthcare professionals are more inclined to utilize repurposed drugs within the same therapeutic area, ensuring quicker acceptance and integration into treatment protocols. On the other hand, the Different Therapeutic Area segment represents an emerging opportunity, showcasing innovation and the potential for lucrative outcomes as drugs are explored for new uses. Driven by groundbreaking research and an increasing number of clinical trials, this segment is poised for rapid growth, with potential applications spanning various conditions, thus attracting significant investment and attention from pharmaceutical companies.

By Drug Molecules: Biologics (Largest) vs. Small Molecule (Fastest-Growing)

In the South America drug repurposing market, the distribution of market share reveals that Biologics hold the largest segment, dominating due to their wide applicability in treating complex diseases. Small Molecule substances, while smaller in share, are rapidly gaining traction owing to their ease of manufacturing and development, making them an attractive alternative for many drug developers. The diversification in therapeutic areas plays a significant role in this distribution. The growth trends in this market are driven by the increasing interest in Biologics, particularly in the realm of monoclonal antibodies and targeted therapies that address specific ailments. Conversely, the Small Molecule segment is experiencing rapid growth due to advancements in technology that streamline the drug repurposing process. This includes enhanced computational methods for drug screening and the expanding pipeline of generic drugs that provide cost-effective treatment options, appealing to both healthcare providers and patients alike.

Biologics (Dominant) vs. Small Molecule (Emerging)

Biologics are currently positioned as the dominant force in the drug repurposing landscape, leveraging their ability to target specific pathways and produce significant therapeutic effects. They are characterized by their complex structures, which require intricate manufacturing processes, giving them a competitive edge in treating challenging health conditions. On the other hand, Small Molecule drugs are emerging as a vital segment with a growing presence. They are simpler in structure and can be administered orally, leading to vast potential in therapeutic applications across various indications. The increase in research initiatives and funding for both segments signifies the evolving landscape, showcasing the dynamic interplay between these two drug categories.

Get more detailed insights about South America Drug Repurposing Market

Regional Insights

Brazil : Strong Growth Driven by Innovation

Brazil holds the largest market share in South America at 18.0%, reflecting a robust drug repurposing sector valued at approximately $1.5 billion. Key growth drivers include increasing healthcare expenditure, a rising prevalence of chronic diseases, and supportive government initiatives aimed at fostering pharmaceutical innovation. Regulatory policies are becoming more favorable, with streamlined approval processes for repurposed drugs, enhancing market accessibility. Additionally, Brazil's well-established healthcare infrastructure supports extensive clinical trials and research activities.

Mexico : Growing Demand and Investment Opportunities

Mexico commands a 10.0% market share in the South American drug repurposing landscape, valued at around $800 million. The market is driven by increasing investments in healthcare and a growing demand for affordable treatment options. The government has initiated several programs to support pharmaceutical research, including tax incentives for companies involved in drug repurposing. The consumption pattern is shifting towards more innovative therapies, reflecting a broader acceptance of repurposed drugs in clinical settings.

Argentina : Focus on Localized Healthcare Solutions

With a 7.0% market share, Argentina's drug repurposing market is valued at approximately $600 million. The growth is fueled by a rising incidence of diseases and a push for localized healthcare solutions. Government policies are increasingly supportive, with initiatives aimed at enhancing research capabilities and funding for clinical trials. The demand for repurposed drugs is growing, particularly in urban areas where healthcare access is improving, driven by public health campaigns and awareness.

Rest of South America : Untapped Markets Awaiting Exploration

The Rest of South America holds a 5.0% market share in the drug repurposing sector, valued at about $400 million. This sub-region presents diverse opportunities, driven by varying healthcare needs and regulatory environments. Countries like Chile and Colombia are emerging as potential markets due to their improving healthcare systems and increasing investment in pharmaceutical research. The competitive landscape is fragmented, with local players gaining traction alongside multinational corporations, creating a dynamic business environment.

South America Drug Repurposing Market Regional Image

Key Players and Competitive Insights

The drug repurposing market in South America is characterized by a dynamic competitive landscape, driven by the increasing need for cost-effective therapeutic solutions and the rising prevalence of chronic diseases. Major players such as Pfizer (US), Novartis (CH), and AstraZeneca (GB) are strategically positioned to leverage their extensive research capabilities and established market presence. These companies are focusing on innovation and partnerships to enhance their drug repurposing initiatives, thereby shaping a competitive environment that emphasizes collaboration and technological advancement.

Key business tactics employed by these companies include localizing manufacturing and optimizing supply chains to improve efficiency and reduce costs. The market appears moderately fragmented, with a mix of large multinational corporations and smaller biotech firms. The collective influence of these key players is significant, as they not only drive innovation but also set industry standards that smaller entities often follow.

In October 2025, Pfizer (US) announced a collaboration with a local biotech firm to explore the repurposing of existing therapies for rare diseases prevalent in South America. This strategic move is likely to enhance Pfizer's portfolio while addressing unmet medical needs in the region, thereby reinforcing its commitment to localized healthcare solutions. Such partnerships may also facilitate faster regulatory approvals and market access.

In September 2025, Novartis (CH) launched a new initiative aimed at repurposing its existing oncology drugs for use in treating autoimmune disorders. This initiative underscores Novartis's focus on leveraging its existing drug library to discover new therapeutic applications, potentially reducing development timelines and costs. The strategic importance of this move lies in its ability to diversify Novartis's product offerings while addressing significant health challenges in the region.

In August 2025, AstraZeneca (GB) expanded its research collaboration with academic institutions in Brazil to investigate the repurposing of its cardiovascular drugs for neurological conditions. This strategic action highlights AstraZeneca's commitment to innovation through academic partnerships, which may lead to groundbreaking discoveries and enhance its competitive edge in the market. The collaboration is expected to yield valuable insights that could inform future drug development strategies.

As of November 2025, current trends in the drug repurposing market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) in research and development processes. Strategic alliances are becoming more prevalent, as companies recognize the value of collaborative efforts in accelerating drug discovery and enhancing patient outcomes. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability, positioning companies to better meet the complex demands of the healthcare landscape.

Key Companies in the South America Drug Repurposing Market market include

Industry Developments

Recent developments in the South America Drug Repurposing Market are notable, particularly with companies like AstraZeneca, Roche, and Merck and Co., which have accelerated their efforts in innovative drug reuse strategies amid growing public health challenges. The pandemic has led to enhanced collaboration among pharmaceutical firms, including a surge in partnerships between Eli Lilly and Sanofi for joint initiatives focusing on repurposed therapies in treating infectious diseases prevalent in the region. 

In August 2023, AstraZeneca announced its plans to invest in strengthening its Research and Development capabilities, specifically targeting diseases endemic to South America. Additionally, there was a reported acquisition of a smaller biotech firm by Roche in September 2023, aimed at enhancing their portfolio in rare disease treatments that could benefit from repurposing existing drugs. Over the last two to three years, significant market growth is observed, especially with Novartis and Pfizer working on developing treatment protocols for conditions like COVID-19 and its long-term effects, significantly impacting local healthcare systems.

This growth underscores the increasing importance of drug repurposing in addressing unmet medical needs across South America.

Future Outlook

South America Drug Repurposing Market Future Outlook

The drug repurposing market is projected to grow at a 15.0% CAGR from 2024 to 2035, driven by increasing R&D investments and regulatory support.

New opportunities lie in:

  • Development of AI-driven drug screening platforms
  • Partnerships with biotech firms for clinical trials
  • Expansion of telehealth services for patient monitoring

By 2035, the market is expected to achieve substantial growth and innovation.

Market Segmentation

South America Drug Repurposing Market Type Outlook

  • Disease-centric
  • Target-centric
  • Drug-centric

South America Drug Repurposing Market Drug Molecules Outlook

  • Biologics
  • Small Molecule

South America Drug Repurposing Market Therapeutic Area Outlook

  • Same Therapeutic Area
  • Different Therapeutic Area

Report Scope

MARKET SIZE 202440.0(USD Million)
MARKET SIZE 202546.0(USD Million)
MARKET SIZE 2035186.13(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)15.0% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Pfizer (US)", "Novartis (CH)", "Bristol-Myers Squibb (US)", "Johnson & Johnson (US)", "AstraZeneca (GB)", "Roche (CH)", "Eli Lilly and Company (US)", "GSK (GB)", "Sanofi (FR)"]
Segments CoveredType, Therapeutic Area, Drug Molecules
Key Market OpportunitiesEmerging technologies enhance efficiency in drug repurposing, addressing unmet medical needs and regulatory challenges.
Key Market DynamicsGrowing interest in drug repurposing driven by regulatory support and technological advancements in South America.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the expected market size of the South America Drug Repurposing Market in 2024?

The South America Drug Repurposing Market is expected to be valued at approximately 33.8 million USD in 2024.

What is the projected market size for the South America Drug Repurposing Market by 2035?

By 2035, the market is projected to reach a value of around 152.1 million USD.

What is the expected CAGR of the South America Drug Repurposing Market from 2025 to 2035?

The expected CAGR for the South America Drug Repurposing Market is approximately 14.652% from 2025 to 2035.

What are the key regions contributing to the South America Drug Repurposing Market?

The key regions include Brazil, Mexico, Argentina, and the Rest of South America.

Which region is expected to have the largest market share in 2024 within South America?

In 2024, Brazil is expected to hold the largest market share, valued at around 10.0 million USD.

How is the Drug-centric segment expected to perform by 2035?

The Drug-centric segment of the market is projected to grow to approximately 53.1 million USD by 2035.

What is the market share of the Disease-centric segment in 2024?

In 2024, the Disease-centric segment is valued at about 10.0 million USD.

Who are the major players in the South America Drug Repurposing Market?

Major players include AstraZeneca, Roche, Merck & Co, and Amgen among others.

What is the market size for the Target-centric segment in 2035?

The Target-centric segment is expected to reach a market size of approximately 54.0 million USD by 2035.

What challenges are currently facing the South America Drug Repurposing Market?

Challenges include regulatory hurdles and the need for extensive clinical validation in drug repurposing.

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