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South America Heart Failure Drugs Market

ID: MRFR/MED/50694-HCR
200 Pages
Garvit Vyas
October 2025

South America Heart Failure Drugs Market Size, Growth Research Report By Drug Class (Angiotensin-Converting Enzyme Inhibitors, Beta Blockers, Diuretics, Angiotensin II Receptor Blockers, Mineralocorticoid Receptor Antagonists), By Administration Route (Oral, Intravenous, Subcutaneous), By Patient Type (Acute Heart Failure, Chronic Heart Failure, Heart Failure with Preserved Ejection Fraction), By Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Online Pharmacy) and By Regional (Brazil, Mexico, Argentina, Rest of South America)- Comp... read more

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South America Heart Failure Drugs Market Infographic
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South America Heart Failure Drugs Market Summary

As per MRFR analysis, the South America heart failure-drugs market Size was estimated at 1500.0 USD Million in 2024. The South America heart failure-drugs market is projected to grow from 1532.55 USD Million in 2025 to 1900.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 2.17% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America heart failure-drugs market is experiencing robust growth driven by various factors.

  • The rising prevalence of heart failure in South America is prompting increased demand for effective treatment options.
  • Brazil remains the largest market for heart failure drugs, while Mexico is recognized as the fastest-growing region in this sector.
  • Innovative therapeutic approaches and enhanced regulatory support are shaping the landscape of heart failure drug development.
  • Key market drivers include the increasing aging population and rising healthcare expenditure, which are likely to bolster market growth.

Market Size & Forecast

2024 Market Size 1500.0 (USD Million)
2035 Market Size 1900.0 (USD Million)

Major Players

Novartis (CH), Bristol-Myers Squibb (US), Merck & Co (US), Amgen (US), Bayer (DE), Pfizer (US), Gilead Sciences (US), AstraZeneca (GB)

South America Heart Failure Drugs Market Trends

The heart failure-drugs market in South America is currently experiencing notable developments, driven by an increasing prevalence of heart failure and a growing awareness of cardiovascular health. The region's healthcare systems are gradually adapting to the rising demand for effective treatments, which has led to a surge in the availability of innovative therapies. Furthermore, the collaboration between pharmaceutical companies and local healthcare providers appears to be enhancing access to essential medications, thereby improving patient outcomes. This evolving landscape suggests a potential for growth as stakeholders focus on addressing the unique challenges faced by patients in South America. In addition, regulatory frameworks in South America are evolving to facilitate the approval and distribution of heart failure-drugs. Governments are increasingly recognizing the importance of cardiovascular health, which may lead to more supportive policies and funding for research and development. As a result, the heart failure-drugs market is likely to witness a diversification of treatment options, including both established therapies and novel agents. This trend indicates a promising future for patients and healthcare providers alike, as the region strives to improve heart health and reduce the burden of heart failure.

Rising Prevalence of Heart Failure

The heart failure-drugs market is witnessing a rise in demand due to the increasing incidence of heart failure in South America. Factors such as aging populations and lifestyle changes contribute to this trend, prompting healthcare systems to seek effective treatment solutions.

Innovative Therapeutic Approaches

There is a growing emphasis on the development of innovative therapies within the heart failure-drugs market. Pharmaceutical companies are focusing on research and development to introduce new medications that offer improved efficacy and safety profiles for patients.

Enhanced Regulatory Support

Regulatory bodies in South America are becoming more supportive of the heart failure-drugs market. This shift may lead to streamlined approval processes for new treatments, ultimately improving patient access to essential medications.

South America Heart Failure Drugs Market Drivers

Increasing Aging Population

The aging population in South America is a critical driver for the heart failure-drugs market. As individuals age, the risk of developing heart failure escalates, leading to a higher demand for effective treatments. In 2025, it is estimated that approximately 15% of the population in South America will be over 65 years old, a demographic that is particularly susceptible to cardiovascular diseases. This demographic shift necessitates the development and availability of heart failure drugs, as healthcare systems strive to manage the growing burden of heart-related ailments. Consequently, pharmaceutical companies are likely to invest in research and development to cater to this expanding market, thereby enhancing the heart failure-drugs market in the region.

Rising Healthcare Expenditure

Healthcare expenditure in South America has been on an upward trajectory, which significantly impacts the heart failure-drugs market. Governments and private sectors are increasingly allocating funds to improve healthcare infrastructure and access to medications. In 2025, healthcare spending in the region is projected to reach $1 trillion, with a notable portion directed towards chronic disease management, including heart failure. This increase in funding facilitates the availability of advanced heart failure drugs, enabling healthcare providers to offer better treatment options. Moreover, as patients gain access to innovative therapies, the overall quality of care improves, further driving the demand for heart failure medications.

Growing Awareness and Education

There is a notable increase in awareness and education regarding heart failure in South America, which serves as a significant driver for the heart failure-drugs market. Public health campaigns and initiatives by healthcare organizations aim to educate the population about the symptoms, risks, and management of heart failure. As awareness grows, more individuals are likely to seek medical attention, leading to earlier diagnosis and treatment. This trend is expected to result in a higher prescription rate of heart failure drugs, as healthcare providers respond to the increased demand for effective therapies. Consequently, the heart failure-drugs market is poised for growth as more patients are diagnosed and treated.

Increased Collaboration Between Stakeholders

Increased collaboration between stakeholders, including pharmaceutical companies, healthcare providers, and government agencies, is a driving force in the heart failure-drugs market. Partnerships and alliances are being formed to enhance research efforts, share resources, and improve access to medications. In 2025, collaborative initiatives are expected to focus on addressing the challenges of heart failure management, such as improving patient adherence to treatment regimens. This collaborative approach not only fosters innovation but also ensures that patients receive timely access to the latest heart failure drugs. As stakeholders work together, the heart failure-drugs market is likely to benefit from enhanced product availability and improved patient outcomes.

Technological Advancements in Drug Development

Technological advancements in drug development are transforming the heart failure-drugs market in South America. Innovations such as artificial intelligence and machine learning are streamlining the drug discovery process, enabling faster and more efficient development of new therapies. In 2025, it is anticipated that the introduction of novel drug formulations and delivery systems will enhance treatment outcomes for heart failure patients. These advancements not only improve the efficacy of existing medications but also pave the way for personalized treatment approaches. As a result, the heart failure-drugs market is likely to experience a surge in new product launches, catering to the diverse needs of patients.

Market Segment Insights

By Drug Class: Angiotensin II Receptor Blockers (Largest) vs. Beta Blockers (Fastest-Growing)

The market share distribution among the drug classes reveals a strong preference for Angiotensin II Receptor Blockers, which currently hold a significant portion of the market due to their effective management of heart failure symptoms. Beta Blockers also represent a meaningful share, appealing to physicians for their dual efficacy in heart failure and hypertension cases. Other drug classes like Diuretics, Angiotensin-Converting Enzyme Inhibitors, and Mineralocorticoid Receptor Antagonists are also present but lag behind in terms of market share, showcasing varied treatment preferences across the region. Growing awareness of heart failure management and increasing investments in healthcare are driving trends within the drug class segment. Angiotensin II Receptor Blockers continue to dominate thanks to their established clinical benefits, while Beta Blockers are emerging rapidly thanks to innovations in formulations and increased acceptance in treatment protocols. The evolving healthcare landscape, paired with a rising geriatric population, fuels the demand for these treatments, pushing them into the spotlight as crucial components of heart failure therapy.

Angiotensin II Receptor Blockers (Dominant) vs. Beta Blockers (Emerging)

Angiotensin II Receptor Blockers are known for their effectiveness in reducing the workload on the heart while aiding in blood pressure management, making them a dominant choice among healthcare providers. Their strong clinical backing and ability to address multiple comorbidities contribute to their widespread use. Conversely, Beta Blockers are rapidly emerging as preferred options, particularly as new formulations offer enhanced benefits and fewer side effects. The flexibility in their application for different heart failure types, coupled with robust clinical evidence, is resulting in a growing market share and acceptance. As both drug classes evolve, they represent pivotal therapies, but their market strategies differ significantly, with Beta Blockers focusing on innovative approaches to capture emerging needs in patient care.

By Administration Route: Oral (Largest) vs. Intravenous (Fastest-Growing)

The administration route segment of heart failure drugs reveals a diverse distribution of market share among oral, intravenous, and subcutaneous routes. Oral administration remains the largest segment, driven by its convenience and ease of use for patients. In contrast, intravenous administration, while not holding the largest share, is recognized for its rapid effects in acute settings and is gaining traction among healthcare professionals. Growth trends in the administration route segment are significantly influenced by the increasing prevalence of heart failure conditions in South America. The preference for oral medications continues to grow as they provide better adherence and patient satisfaction. However, advancements in intravenous formulations are also propelling this segment forward, particularly in hospital settings where quick therapeutic responses are crucial, making it the fastest-growing route in the market.

Oral (Dominant) vs. Intravenous (Emerging)

The oral administration route is clearly the dominant player in the heart failure drugs segment, highly favored for its practicality and patient compliance. Many patients prefer oral medications, as they can be taken at home, which fosters adherence to treatment plans. Conversely, the intravenous route is emerging as a vital alternative, especially in hospital environments where rapid intervention is necessary. Its ability to deliver immediate effects makes it indispensable in acute care settings. As the market evolves, both routes are likely to complement each other, with oral medications leading in day-to-day treatment while intravenous options become essential for emergency care.

By Patient Type: Chronic Heart Failure (Largest) vs. Acute Heart Failure (Fastest-Growing)

In the Patient Type segment, Chronic Heart Failure represents the largest share, dominating the market landscape. This segment's substantial market presence is mainly due to the high prevalence of chronic conditions among the population. Meanwhile, Acute Heart Failure is emerging as a significant player, showing rapid growth, fueled by increased awareness and advancements in clinical therapies. The growth trends in this segment are influenced by an aging population, lifestyle changes, and the rising incidence of heart failure. Innovative treatment options and enhanced patient management strategies contribute to the expansion of both Chronic and Acute Heart Failure markets. Heart Failure with Preserved Ejection Fraction is gaining attention but remains overshadowed by the larger segments, making it a critical area for future developments.

Chronic Heart Failure (Dominant) vs. Acute Heart Failure (Emerging)

Chronic Heart Failure is characterized by a long-term condition requiring ongoing management and treatment. It accounts for a substantial portion of the market due to its chronic nature and the need for sustained therapies. Patients in this category often rely on a combination of medications and lifestyle modifications to manage their symptoms effectively. In contrast, Acute Heart Failure is marked by sudden episodes that necessitate immediate medical attention, driving growth in that segment. This category is increasingly recognized for its urgent care demands, leading to innovations in treatment approaches. Both patient types reflect distinct treatment pathways and market opportunities within the industry.

By Distribution Channel: Hospital Pharmacy (Largest) vs. Online Pharmacy (Fastest-Growing)

In the distribution channel segment, Hospital Pharmacy holds the largest share owing to its established presence and relationships with healthcare providers. This traditional channel benefits from direct access to patients and a comprehensive range of heart failure drugs, providing a reliable distribution pathway. Conversely, Retail Pharmacy also contributes significantly, though it faces intense competition from both Hospital and Online Pharmacies. The growth trends indicate a rising shift towards Online Pharmacy as healthcare consumers increasingly prefer the convenience and accessibility of purchasing medications online. This channel is expected to expand rapidly due to the proliferation of digital platforms and telehealth services, driven by factors such as increased internet penetration and changing consumer behavior towards online services in the pharmaceutical sector.

Hospital Pharmacy (Dominant) vs. Online Pharmacy (Emerging)

Hospital Pharmacy dominates the distribution channels in the heart failure-drugs market, characterized by its strong relationships with physicians and hospitals, ensuring patients receive critical medications directly. Its dominance is underpinned by the trust and loyalty established within healthcare systems. In contrast, Online Pharmacy is emerging as a competitive force, gaining traction among tech-savvy consumers seeking easy access to medications and transparent pricing. The rapid growth of e-commerce in healthcare, influenced by advancements in technology and changing patient preferences, positions Online Pharmacy as a pivotal player in redefining how heart failure drugs are accessed and utilized, making it a crucial segment for future development.

Get more detailed insights about South America Heart Failure Drugs Market

Regional Insights

Brazil : Robust Growth and Demand Trends

Brazil holds a commanding market share of 48% in the heart failure-drugs sector, valued at $600.0 million. Key growth drivers include an aging population, increasing prevalence of cardiovascular diseases, and government initiatives aimed at improving healthcare access. Regulatory policies have been favorable, with the National Health Surveillance Agency (ANVISA) streamlining drug approvals. Infrastructure improvements in healthcare facilities further bolster market demand.

Mexico : Growing Demand for Innovative Therapies

Mexico accounts for 29% of the South American heart failure-drugs market, valued at $350.0 million. The rise in heart disease cases and increased healthcare spending are significant growth drivers. Demand for innovative therapies is on the rise, supported by government initiatives to enhance healthcare access. Regulatory frameworks are becoming more favorable, encouraging pharmaceutical investments and local production.

Argentina : Navigating Economic Fluctuations

Argentina represents 25% of the heart failure-drugs market in South America, valued at $300.0 million. Economic challenges have impacted healthcare spending, yet the demand for heart failure treatments remains strong due to rising disease prevalence. Government policies are focused on improving healthcare access, although regulatory hurdles persist. The market is characterized by a mix of local and international players, driving competition.

Rest of South America : Varied Demand Across Regions

The Rest of South America holds a market share of 21% in heart failure drugs, valued at $250.0 million. This sub-region includes countries like Chile, Colombia, and Peru, each with distinct healthcare challenges and opportunities. Growth is driven by increasing awareness of heart diseases and government initiatives to improve healthcare infrastructure. Regulatory environments vary, impacting market entry for foreign players.

South America Heart Failure Drugs Market Regional Image

Key Players and Competitive Insights

The heart failure-drugs market in South America is characterized by a dynamic competitive landscape, driven by increasing prevalence of heart failure and a growing demand for innovative therapies. Key players such as Novartis (CH), Bristol-Myers Squibb (US), and Merck & Co (US) are actively shaping the market through strategic initiatives focused on innovation, partnerships, and regional expansion. Novartis (CH) has positioned itself as a leader in the development of novel therapies, while Bristol-Myers Squibb (US) emphasizes its commitment to research and development, particularly in the realm of heart failure. Merck & Co (US) is also enhancing its portfolio through strategic collaborations, which collectively contribute to a competitive environment that is increasingly focused on advanced therapeutic solutions.

In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance efficiency and responsiveness to market demands. The competitive structure of the market appears moderately fragmented, with several key players exerting influence. This fragmentation allows for a diverse range of products and strategies, fostering innovation while also presenting challenges in terms of market share and brand loyalty.

In October 2025, Novartis (CH) announced a strategic partnership with a local biotechnology firm to accelerate the development of heart failure therapies tailored to the South American population. This collaboration is significant as it not only enhances Novartis's research capabilities but also demonstrates a commitment to addressing regional health needs, potentially leading to improved patient outcomes and market penetration.

In September 2025, Bristol-Myers Squibb (US) launched a new heart failure drug that has shown promising results in clinical trials. This launch is pivotal as it reinforces the company's focus on innovation and its ability to bring cutting-edge therapies to market. The introduction of this drug is likely to strengthen Bristol-Myers Squibb's position in the competitive landscape, appealing to healthcare providers seeking effective treatment options.

In August 2025, Merck & Co (US) expanded its distribution network in South America, aiming to enhance access to its heart failure medications. This strategic move is crucial as it not only increases the availability of their products but also aligns with the growing demand for heart failure treatments in the region. By optimizing its distribution channels, Merck & Co (US) is likely to improve its market share and customer loyalty.

As of November 2025, current trends in the heart failure-drugs market include a strong emphasis on digitalization, sustainability, and the integration of artificial intelligence in drug development. Strategic alliances are increasingly shaping the competitive landscape, allowing companies to leverage shared resources and expertise. Looking ahead, competitive differentiation is expected to evolve, with a shift from price-based competition to a focus on innovation, technology, and supply chain reliability. This transition may redefine how companies approach market entry and product development, ultimately benefiting patients through enhanced therapeutic options.

Key Companies in the South America Heart Failure Drugs Market market include

Industry Developments

The South America Heart Failure Drugs Market is currently experiencing significant developments, with key players such as AstraZeneca, Merck and Co, and Roche actively expanding their product lines. In September 2023, AstraZeneca announced the launch of a new heart failure therapy, aimed at addressing the increasing prevalence of heart diseases in countries like Brazil and Argentina. Merck and Co recently received regulatory approval for a new heart failure treatment in Chile, reflecting a growing focus on improving healthcare access. Additionally, the influx of advanced therapies from companies like Bristol Myers Squibb and Amgen is reshaping treatment standards.

In terms of mergers and acquisitions, Sanofi completed the acquisition of a local biotech firm in August 2023 to enhance its position in the region, further bolstering its heart failure portfolio. The market valuation for heart failure drugs is expected to grow substantially, influenced by the rising incidence of cardiovascular diseases fueled by lifestyle changes and aging populations.

Over the last two years, there has been a notable increase in investment in Research and Development efforts, emphasizing the urgency to innovate and provide effective solutions for heart failure patients across South America, particularly as healthcare systems strive to adapt to increased demands.

Future Outlook

South America Heart Failure Drugs Market Future Outlook

The heart failure-drugs market is projected to grow at 2.17% CAGR from 2024 to 2035, driven by increasing prevalence and advancements in drug formulations.

New opportunities lie in:

  • Development of personalized medicine approaches for heart failure treatment.
  • Expansion of telehealth services for remote patient monitoring.
  • Investment in AI-driven drug discovery platforms to enhance R&D efficiency.

By 2035, the heart failure-drugs market is expected to achieve substantial growth and innovation.

Market Segmentation

South America Heart Failure Drugs Market Drug Class Outlook

  • Angiotensin-Converting Enzyme Inhibitors
  • Beta Blockers
  • Diuretics
  • Angiotensin II Receptor Blockers
  • Mineralocorticoid Receptor Antagonists

South America Heart Failure Drugs Market Patient Type Outlook

  • Acute Heart Failure
  • Chronic Heart Failure
  • Heart Failure with Preserved Ejection Fraction

South America Heart Failure Drugs Market Administration Route Outlook

  • Oral
  • Intravenous
  • Subcutaneous

South America Heart Failure Drugs Market Distribution Channel Outlook

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

Report Scope

MARKET SIZE 20241500.0(USD Million)
MARKET SIZE 20251532.55(USD Million)
MARKET SIZE 20351900.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)2.17% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Novartis (CH)", "Bristol-Myers Squibb (US)", "Merck & Co (US)", "Amgen (US)", "Bayer (DE)", "Pfizer (US)", "Gilead Sciences (US)", "AstraZeneca (GB)"]
Segments CoveredDrug Class, Administration Route, Patient Type, Distribution Channel
Key Market OpportunitiesEmerging therapies targeting heart failure with preserved ejection fraction present a notable opportunity in the heart failure-drugs market.
Key Market DynamicsRising demand for innovative heart failure therapies drives competition and regulatory adaptations in South America.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the expected market size of the South America Heart Failure Drugs Market in 2024?

The South America Heart Failure Drugs Market is expected to be valued at 1.5 USD Billion in 2024.

What will the South America Heart Failure Drugs Market be valued at by 2035?

By 2035, the South America Heart Failure Drugs Market is projected to reach a value of 2.0 USD Billion.

What is the expected CAGR for the South America Heart Failure Drugs Market from 2025 to 2035?

The expected CAGR for the South America Heart Failure Drugs Market from 2025 to 2035 is 2.65%.

Which region is expected to dominate the South America Heart Failure Drugs Market in 2024?

Brazil is expected to dominate the South America Heart Failure Drugs Market with a value of 0.55 USD Billion in 2024.

What is the anticipated market size for Angiotensin-Converting Enzyme Inhibitors in 2024?

The market size for Angiotensin-Converting Enzyme Inhibitors is anticipated to be 0.45 USD Billion in 2024.

Which drug class is expected to see significant growth by 2035?

The Beta Blockers class is expected to grow to a market size of 0.45 USD Billion by 2035.

Who are the major players in the South America Heart Failure Drugs Market?

Major players in the market include AstraZeneca, Merck & Co, Roche, Amgen, and Bristol Myers Squibb.

What is the projected market size for Diuretics by 2035?

The market for Diuretics is projected to reach 0.38 USD Billion by 2035.

What is the expected market value for Argentina in 2024?

The expected market value for Argentina in 2024 is 0.2 USD Billion.

How much is the market for Mineralocorticoid Receptor Antagonists expected to grow by 2035?

The market for Mineralocorticoid Receptor Antagonists is expected to grow to 0.27 USD Billion by 2035.

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