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South America hERG Screening Market

ID: MRFR/HC/51280-HCR
200 Pages
Garvit Vyas
October 2025

South America hERG screening Market Research Report By Type (Gene KCNH2, Mutant KCNH2), By Ion Channel (Voltage Gated, Ligand Gated), By Application (Antiarrhythmic, Antipsychotic, Antibiotics, Others) and By Regional (Brazil, Mexico, Argentina, Rest of South America)- Forecast to 2035

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South America hERG Screening Market Summary

As per MRFR analysis, the herg screening market Size was estimated at 56.0 USD Million in 2024. The herg screening market is projected to grow from 61.95 USD Million in 2025 to 170.2 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 10.63% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America Herg screening market is poised for growth driven by regulatory focus and technological advancements.

  • Brazil remains the largest market for Herg screening, reflecting a robust demand for cardiac safety assessments.
  • Mexico is emerging as the fastest-growing region, indicating a rising investment in biopharmaceutical research.
  • Technological advancements in screening methods are enhancing the accuracy and efficiency of Herg testing.
  • The increasing incidence of cardiovascular diseases and growing awareness of drug-induced arrhythmias are key drivers of market expansion.

Market Size & Forecast

2024 Market Size 56.0 (USD Million)
2035 Market Size 170.2 (USD Million)

Major Players

Thermo Fisher Scientific (US), Charles River Laboratories (US), Eurofins Scientific (LU), Celerion (US), CROMSOURCE (IT), Inotiv (US), Celerion (US), Celerion (US)

South America hERG Screening Market Trends

The herg screening market is currently experiencing notable growth, driven by the increasing emphasis on drug safety and regulatory compliance in South America. Regulatory bodies in the region are placing heightened scrutiny on the cardiac safety profiles of new pharmaceuticals, which has led to a surge in demand for herg screening technologies. This trend is further supported by the rising incidence of cardiac-related adverse events associated with various medications, prompting pharmaceutical companies to prioritize herg testing in their development processes. As a result, the market is witnessing a shift towards more sophisticated and efficient screening methods, including high-throughput screening and in silico modeling, which are becoming essential tools for researchers and developers alike. Moreover, the herg screening market is also influenced by advancements in technology and increased collaboration between academic institutions and industry players. These partnerships are fostering innovation and enhancing the capabilities of herg screening methodologies. The growing awareness of the importance of herg testing in drug development is likely to drive further investments in this area, as stakeholders recognize the potential for improved patient safety and reduced liability. Overall, the herg screening market appears poised for continued expansion in South America, reflecting broader trends in the pharmaceutical industry that prioritize safety and efficacy in drug development.

Regulatory Focus on Cardiac Safety

Regulatory agencies in South America are increasingly emphasizing the importance of cardiac safety in drug development. This heightened focus is driving pharmaceutical companies to adopt herg screening as a critical component of their research and development processes, ensuring compliance with safety standards.

Technological Advancements in Screening Methods

Innovations in herg screening technologies are transforming the market landscape. The introduction of high-throughput screening and advanced computational models is enhancing the efficiency and accuracy of herg testing, enabling faster drug development timelines.

Collaborative Research Initiatives

There is a growing trend of collaboration between academic institutions and pharmaceutical companies in South America. These partnerships are fostering research and development in herg screening methodologies, leading to improved testing protocols and enhanced drug safety outcomes.

South America hERG Screening Market Drivers

Rising Cardiovascular Disease Incidence

The increasing prevalence of cardiovascular diseases in South America is a crucial driver for the herg screening market. As healthcare providers focus on improving patient outcomes, the demand for effective screening methods has surged. Reports indicate that cardiovascular diseases account for approximately 30% of all deaths in the region, prompting regulatory bodies to emphasize cardiac safety in drug development. This heightened awareness has led to a growing need for herg screening solutions, as pharmaceutical companies seek to mitigate risks associated with drug-induced arrhythmias. Consequently, the herg screening market is likely to experience significant growth as stakeholders prioritize patient safety and regulatory compliance.

Investment in Biopharmaceutical Research

The herg screening market is witnessing a surge in investment from biopharmaceutical companies in South America. With the region's growing focus on innovative drug development, there is an increasing need for robust screening methods to ensure cardiac safety. In 2025, biopharmaceutical investments in South America are projected to reach $5 billion, reflecting a commitment to enhancing research capabilities. This influx of funding is likely to drive the adoption of advanced herg screening technologies, as companies aim to streamline their drug development processes while adhering to stringent regulatory requirements. As a result, the herg screening market stands to benefit from this trend, fostering innovation and improving patient safety.

Growing Awareness of Drug-Induced Arrhythmias

The herg screening market is experiencing growth due to the increasing awareness of drug-induced arrhythmias among healthcare professionals and regulatory bodies in South America. As the understanding of the risks associated with certain medications expands, there is a heightened emphasis on cardiac safety during drug development. This awareness is reflected in the rising number of training programs and workshops focused on herg screening methodologies. In 2025, it is anticipated that educational initiatives will increase by 15%, further promoting the importance of herg screening in ensuring patient safety. Consequently, the herg screening market is likely to benefit from this trend, as stakeholders prioritize effective screening practices.

Technological Integration in Drug Development

The herg screening market is being propelled by the integration of advanced technologies in drug development processes across South America. The adoption of high-throughput screening methods and automated systems is enhancing the efficiency and accuracy of herg screening. In 2025, it is projected that the market for automated screening technologies will grow by 25%, reflecting the industry's shift towards more sophisticated methodologies. This technological advancement not only streamlines the screening process but also reduces the time and costs associated with drug development. As a result, the herg screening market is likely to see increased investment and innovation, ultimately benefiting patient safety and therapeutic efficacy.

Regulatory Changes and Compliance Requirements

Recent regulatory changes in South America have significantly impacted the herg screening market. Authorities are increasingly mandating comprehensive cardiac safety assessments for new drug applications, which has heightened the demand for herg screening solutions. In 2025, it is estimated that compliance costs for pharmaceutical companies could rise by 20% due to these new regulations. This shift necessitates the integration of herg screening into the drug development pipeline, compelling companies to invest in advanced technologies and methodologies. As a result, the herg screening market is poised for growth, driven by the need for compliance and the assurance of patient safety in drug therapies.

Market Segment Insights

By Type: Gene KCNH2 (Largest) vs. Mutant KCNH2 (Fastest-Growing)

In the market segment, Gene KCNH2 holds a dominant position with a significant share, appealing to a wide range of applications in Herg screening. This segment's extensive utilization is driven by its reliability and recognition in the field, making it the preferred choice for many researchers and laboratories within the region. Conversely, Mutant KCNH2 has emerged as a faster-growing segment, capturing attention due to the increasing focus on personalized medicine and specific genetic profiles. The growth trends for these segments are heavily influenced by advancements in genetic research and therapy advancements. The rise in chronic diseases and the subsequent demand for targeted treatments have prompted researchers to invest more in efficient screening methods. This shift is fostering a competitive landscape, where breakthroughs in mutant gene analysis are rapidly gaining traction, thus positioning Mutant KCNH2 as a segment to watch in the coming years.

Gene KCNH2 (Dominant) vs. Mutant KCNH2 (Emerging)

Gene KCNH2 is recognized as the dominant player in this market, characterized by its established application in Herg screening processes that focus on cardiovascular safety. This segment benefits from wide acceptance among clinical researchers due to its robust data supporting its effectiveness. In contrast, Mutant KCNH2 is viewed as an emerging segment, reflecting growing interest in genetic mutations and their implications for drug interactions and safety assessments. The increasing push for individualized therapies boosts the attractiveness of this segment, as it represents a key area for innovation and potential growth, encouraging stakeholders to explore advanced screening techniques that address specific genetic anomalies.

By Ion Channel: Voltage Gated (Largest) vs. Ligand Gated (Fastest-Growing)

In the South America herg screening market, the distribution of market share between the Ion Channel segment values shows Voltage Gated as the dominant player, capturing a significant share due to its extensive application in drug discovery and safety testing. In contrast, Ligand Gated channels are gaining traction, driven by increasing research activities targeting specific ionic pathways, thereby enhancing their overall market presence. The expansion of these channels in laboratories is a critical factor that is reshaping the market dynamics. Recent trends indicate that Ligand Gated channels are on the rise, marked as the fastest-growing segment owing to heightened interest in personalized medicine and innovative drug development processes. Researchers are focusing more on the unique properties and diverse functions of these channels, which are integral to many physiological processes. The shift towards more targeted therapies is further stimulating growth, pushing Ligand Gated channels into a more prominent role in future research and development, augmenting their strategic importance in the market.

Voltage Gated (Dominant) vs. Ligand Gated (Emerging)

Voltage Gated channels are characterized by their fundamental role in action potentials and excitability of cells, making them crucial for various physiological functions and an essential focus in toxicology studies. Their robust presence in the herg screening market reflects established methodologies widely adopted in drug testing. Conversely, Ligand Gated channels, while currently emerging, exhibit remarkable potential due to their specificity in response to neurotransmitters and other signaling molecules. Enhanced understanding of these channels has led to innovative applications in pharmacology, positioning them as an attractive area for future growth and investment in the South America herg screening market.

By Application: Antiarrhythmic (Largest) vs. Antipsychotic (Fastest-Growing)

The application segment in the market showcases a diverse distribution of market share. Antiarrhythmic drugs dominate this sector, capturing a significant portion due to their vast usage in the treatment of cardiovascular diseases. Meanwhile, antipsychotic medications also hold a notable share, reflecting the increasing awareness and diagnosis of mental health disorders. The antibiotics segment, while important, appears to lag behind in comparison, overshadowed by the rise of more specialized therapeutic applications. Growth trends indicate a shift towards targeted therapies in the application segment. The rise in mental health awareness is propelling antipsychotic drugs as the fastest-growing category, driven by a surge in demand for effective treatment options. Furthermore, the increasing prevalence of cardiac conditions ensures that antiarrhythmic medications continue to remain in high demand, thereby solidifying their position as the largest segment within the market.

Antiarrhythmic (Dominant) vs. Antipsychotic (Emerging)

Antiarrhythmic drugs are the dominant players in the market, primarily utilized to manage various cardiac arrhythmias, showcasing their critical role in therapeutic interventions for heart-related ailments. With a strong reliance on these medications by healthcare professionals, they have secured a dedicated market base. On the other hand, antipsychotic drugs are emerging rapidly in popularity, fueled by a focused response to the growing incidences of mental health issues. Innovations in formulation and an expanding pipeline are set to enhance their market presence, while community initiatives and government policies further support their growth, making them a key segment to watch.

Get more detailed insights about South America hERG Screening Market

Regional Insights

Mexico : Regulatory Support Fuels Growth

With a market share of 10.5%, Mexico's herg screening market is gaining traction, driven by government initiatives aimed at boosting healthcare innovation. The demand for herg screening is increasing due to the growing pharmaceutical industry and rising awareness of drug safety. Regulatory bodies are enhancing frameworks to support clinical trials, which is vital for market expansion. The country's investment in healthcare infrastructure further bolsters this growth.

Argentina : Pharmaceutical Growth Drives Market

Argentina accounts for 12.9% of the South American herg screening market, reflecting a growing demand for drug safety testing. The pharmaceutical sector is expanding, supported by government incentives for research and development. Regulatory frameworks are evolving to ensure compliance with international standards, enhancing market attractiveness. The increasing prevalence of chronic diseases is also driving the need for effective drug testing solutions.

Rest of South America : Potential for Herg Screening Growth

The Rest of South America holds a 7.0% market share in the herg screening sector, with varying demand across countries. Key growth drivers include increasing healthcare investments and a focus on improving drug safety regulations. Countries like Chile and Colombia are emerging as significant players, with supportive government policies fostering innovation. The competitive landscape features both local and international players, enhancing market dynamics.

South America hERG Screening Market Regional Image

Key Players and Competitive Insights

The herg screening market in South America is characterized by a competitive landscape that is increasingly shaped by innovation, strategic partnerships, and regional expansion. Key players such as Thermo Fisher Scientific (US), Charles River Laboratories (US), and Eurofins Scientific (LU) are at the forefront, each adopting distinct strategies to enhance their market presence. Thermo Fisher Scientific (US) focuses on technological advancements in screening methodologies, while Charles River Laboratories (US) emphasizes its comprehensive service offerings, including preclinical and clinical development. Eurofins Scientific (LU) appears to be leveraging its extensive laboratory network to optimize service delivery across the region, thereby enhancing its competitive edge. Collectively, these strategies contribute to a dynamic environment where innovation and service diversification are paramount.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to better serve the South American market. The competitive structure of the herg screening market is moderately fragmented, with several players vying for market share. This fragmentation allows for a variety of service offerings, yet the influence of major players remains significant, as they set benchmarks for quality and innovation that smaller firms often strive to meet.

In October 2025, Thermo Fisher Scientific (US) announced the launch of a new high-throughput herg screening platform designed to enhance drug safety assessments. This strategic move is likely to position the company as a leader in the market, as it addresses the growing demand for efficient and reliable screening solutions. The introduction of this platform not only reflects Thermo Fisher's commitment to innovation but also aligns with the industry's shift towards more automated and scalable solutions.

In September 2025, Charles River Laboratories (US) expanded its partnership with a leading pharmaceutical company to provide integrated herg screening services. This collaboration is indicative of Charles River's strategy to deepen its service offerings and enhance its value proposition to clients. By aligning with a major player in the pharmaceutical sector, Charles River is likely to strengthen its market position and drive revenue growth through increased service utilization.

In August 2025, Eurofins Scientific (LU) acquired a regional laboratory specializing in herg screening, thereby expanding its operational footprint in South America. This acquisition not only enhances Eurofins' capabilities but also allows for greater market penetration. The strategic importance of this move lies in Eurofins' ability to offer localized services, which can significantly improve turnaround times and customer satisfaction.

As of November 2025, the herg screening market is witnessing trends such as digitalization, sustainability, and the integration of artificial intelligence (AI) into screening processes. Strategic alliances are increasingly shaping the competitive landscape, enabling companies to pool resources and expertise. Looking ahead, it appears that competitive differentiation will evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability. This shift suggests that companies that prioritize these areas may gain a substantial advantage in the market.

Key Companies in the South America hERG Screening Market market include

Industry Developments

Recent developments in the South America hERG screening Market indicate a growing emphasis on safety pharmacology as drug manufacturers in the region focus on compliance with international regulations. Notably, Abbott Laboratories and Pfizer are involved in enhancing their respective HERG screening processes to ensure cardiovascular safety for new drug candidates. In July 2023, Roche announced a partnership with a local biotechnology firm to improve drug testing capabilities. Thermo Fisher Scientific has expanded its service offerings in Brazil to cater to the rising demand for HERG screening services.

Financial growth is evident, with market valuations for companies like Celerion and Fujifilm experiencing a notable increase due to investments in innovative screening technologies. 

In terms of mergers and acquisitions, AstraZeneca's acquisition of a small biotech firm in June 2023 has strengthened its research capabilities in pharmacology within the South American market. Major happenings in recent years include Sanofi's establishment of a new research center in Argentina in August 2022, focusing on drug safety evaluations, underlining the importance placed on HERG screening within the regulatory framework of the region. The ongoing developments cater to an evolving landscape where drug safety is becoming increasingly prioritized in South America.

South America hERG Screening Market Segmentation Insights

hERG Screening Market Type Outlook

    • Gene KCNH2
    • Mutant KCNH2

hERG Screening Market Ion Channel Outlook

    • Voltage Gated
    • Ligand Gated

hERG Screening Market Application Outlook

    • Antiarrhythmic
    • Antipsychotic
    • Antibiotics
    • Others

hERG Screening Market Regional Outlook

    • Brazil
    • Mexico
    • Argentina
    • Rest of South America

Future Outlook

South America hERG Screening Market Future Outlook

The herg screening market is projected to grow at a 10.63% CAGR from 2024 to 2035, driven by increasing regulatory demands and technological advancements.

New opportunities lie in:

  • Development of AI-driven screening technologies for enhanced accuracy.
  • Expansion of partnerships with pharmaceutical companies for integrated testing solutions.
  • Launch of mobile herg screening units for remote testing capabilities.

By 2035, the herg screening market is expected to achieve substantial growth and innovation.

Market Segmentation

South America hERG Screening Market Type Outlook

  • Gene KCNH2
  • Mutant KCNH2

South America hERG Screening Market Application Outlook

  • Antiarrhythmic
  • Antipsychotic
  • Antibiotics
  • Others

South America hERG Screening Market Ion Channel Outlook

  • Voltage Gated
  • Ligand Gated

Report Scope

MARKET SIZE 202456.0(USD Million)
MARKET SIZE 202561.95(USD Million)
MARKET SIZE 2035170.2(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)10.63% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Thermo Fisher Scientific (US)", "Charles River Laboratories (US)", "Eurofins Scientific (LU)", "Celerion (US)", "CROMSOURCE (IT)", "Inotiv (US)", "Celerion (US)", "Celerion (US)"]
Segments CoveredType, Ion Channel, Application
Key Market OpportunitiesEmerging technologies enhance herg screening efficiency, addressing regulatory demands and safety concerns in drug development.
Key Market DynamicsRising regulatory scrutiny drives demand for advanced human ether-a-go-go related gene screening technologies in South America.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the projected market size of the South America HERG Screening Market in 2024?

The South America HERG Screening Market is projected to be valued at 89.6 million USD in 2024.

What is the expected value of the South America HERG Screening Market by 2035?

By 2035, the market is anticipated to reach a value of 287.18 million USD.

What is the expected CAGR for the South America HERG Screening Market from 2025 to 2035?

The market is expected to grow at a CAGR of 11.17% from 2025 to 2035.

Which region is expected to have the largest market share in the South America HERG Screening Market?

Brazil is expected to dominate the market with values of 30.0 million USD in 2024 and 95.0 million USD in 2035.

What is the market size of the Gene KCNH2 segment in 2024?

The Gene KCNH2 segment of the market is valued at 35.0 million USD in 2024.

How much is the Mutant KCNH2 segment projected to be worth in 2035?

The Mutant KCNH2 segment is projected to be valued at 174.55 million USD by 2035.

What are the projected values for the HERG Screening Market in Mexico by 2035?

The market in Mexico is expected to reach a value of 80.0 million USD by 2035.

What is the expected market size for Argentina in 2024?

In 2024, the HERG Screening Market in Argentina is expected to be valued at 20.0 million USD.

Who are the key players in the South America HERG Screening Market?

Major players include Abbott Laboratories, Pfizer, Roche, and Merck & Co among others.

What is the expected size of the Rest of South America segment in 2035?

The Rest of South America segment is anticipated to reach a value of 47.18 million USD by 2035.

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