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South Korea Pegylated Drugs Market

ID: MRFR/Pharma/48022-HCR
200 Pages
Rahul Gotadki
October 2025

South Korea Pegylated Drugs Market Research Report By Molecule (Protein, FAB’ Fragment, Enzyme, Aptamer) and By Indication (Cancer, Gout, Hemophilia, Hepatitis)- Forecast to 2035

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South Korea Pegylated Drugs Market Infographic
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South Korea Pegylated Drugs Market Summary

As per MRFR analysis, the South Korea pegylated drugs market size was estimated at 379.5 USD Million in 2024. The South Korea pegylated drugs market is projected to grow from 403.22 USD Million in 2025 to 739.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 6.25% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South Korea pegylated drugs market is poised for growth driven by innovation and increasing demand for targeted therapies.

  • The market is witnessing a rising demand for targeted therapies, particularly in oncology and autoimmune diseases.
  • Government support for biopharmaceutical innovation is fostering a conducive environment for market expansion.
  • Advancements in manufacturing technologies are enhancing the efficiency and scalability of pegylated drug production.
  • The increasing prevalence of chronic diseases and rising awareness of personalized medicine are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 379.5 (USD Million)
2035 Market Size 739.0 (USD Million)
CAGR (2025 - 2035) 6.25%

Major Players

Amgen (US), Roche (CH), Merck (US), Pfizer (US), Novartis (CH), Bristol-Myers Squibb (US), Eli Lilly (US), AstraZeneca (GB), Gilead Sciences (US)

South Korea Pegylated Drugs Market Trends

The pegylated drugs market in South Korea is experiencing notable growth, driven by advancements in biotechnology and increasing demand for innovative therapies. Pegylation, a process that enhances the pharmacokinetics of drugs, is becoming increasingly important in the development of biopharmaceuticals. This market is characterized by a diverse range of applications, including oncology, infectious diseases, and chronic conditions. The South Korean government actively supports research and development initiatives, fostering an environment conducive to innovation. As a result, local companies are increasingly investing in pegylated drug development, aiming to meet both domestic and international needs. Moreover, the regulatory landscape in South Korea is evolving to accommodate the unique challenges posed by pegylated drugs. Regulatory bodies are working to streamline approval processes, which may enhance the speed at which new therapies reach the market. The growing prevalence of diseases requiring long-term treatment options is likely to further propel the demand for pegylated formulations. In addition, collaborations between academic institutions and pharmaceutical companies are becoming more common, potentially leading to breakthroughs in drug development. Overall, the pegylated drugs market appears poised for continued expansion in South Korea, reflecting broader trends in the biopharmaceutical sector.

Rising Demand for Targeted Therapies

The pegylated drugs market is witnessing an increase in demand for targeted therapies, particularly in oncology. As healthcare providers seek more effective treatment options, pegylated formulations are gaining traction due to their ability to improve drug delivery and reduce side effects. This trend is likely to continue as more patients seek personalized medicine solutions.

Government Support for Biopharmaceutical Innovation

The South Korean government is actively promoting biopharmaceutical innovation, which is beneficial for the pegylated drugs market. Initiatives aimed at enhancing research funding and fostering public-private partnerships are expected to stimulate growth. This support may lead to the development of novel pegylated therapies that address unmet medical needs.

Advancements in Manufacturing Technologies

Technological advancements in the manufacturing of pegylated drugs are transforming the market landscape. Innovations in production processes are likely to enhance efficiency and reduce costs, making pegylated therapies more accessible. As these technologies evolve, they may facilitate the introduction of new products into the market.

South Korea Pegylated Drugs Market Drivers

Growing Investment in Biotechnology

Investment in biotechnology is surging in South Korea, serving as a significant catalyst for the pegylated drugs market. The government and private sector are channeling substantial funds into research and development initiatives aimed at advancing biopharmaceutical technologies. This influx of capital is likely to accelerate the discovery and commercialization of pegylated drugs, which are increasingly recognized for their therapeutic potential. The pegylated drugs market stands to gain from this trend, as enhanced funding supports innovation and the development of new therapies that address unmet medical needs.

Advancements in Drug Delivery Systems

Innovations in drug delivery systems are significantly influencing the pegylated drugs market. Enhanced delivery mechanisms, such as targeted delivery and controlled release, are being developed to improve therapeutic efficacy and patient compliance. Pegylation technology allows for the modification of drug properties, leading to improved solubility and bioavailability. In South Korea, the integration of nanotechnology and biocompatible materials in drug formulation is gaining traction. This evolution in drug delivery systems is expected to propel the pegylated drugs market forward, as healthcare professionals increasingly adopt these advanced therapies to optimize treatment outcomes.

Increasing Prevalence of Chronic Diseases

The rising incidence of chronic diseases in South Korea is a pivotal driver for the pegylated drugs market. Conditions such as cancer, diabetes, and autoimmune disorders are becoming more prevalent, necessitating innovative treatment options. Pegylated drugs, known for their extended half-life and reduced immunogenicity, are increasingly being utilized in therapeutic regimens. According to recent health statistics, chronic diseases account for approximately 80% of healthcare expenditures in the country. This trend indicates a growing demand for effective therapies, positioning pegylated drugs as a vital component in the treatment landscape. The pegylated drugs market is likely to benefit from this increasing patient population, as healthcare providers seek advanced solutions to manage these complex conditions.

Regulatory Support for Biopharmaceuticals

Regulatory frameworks in South Korea are becoming increasingly supportive of biopharmaceutical innovations, which is a crucial driver for the pegylated drugs market. The government has implemented policies aimed at expediting the approval process for new drugs, particularly those that demonstrate significant therapeutic benefits. This regulatory environment encourages research and development in the pegylated drugs market, fostering a landscape where biopharmaceutical companies can thrive. As a result, the number of pegylated drugs entering the market is expected to rise, providing patients with more treatment options and enhancing overall healthcare outcomes.

Rising Awareness of Personalized Medicine

The growing awareness and acceptance of personalized medicine in South Korea is driving the pegylated drugs market. Patients and healthcare providers are increasingly recognizing the benefits of tailored therapies that consider individual genetic and phenotypic characteristics. Pegylated drugs, with their ability to enhance drug efficacy and minimize side effects, align well with the principles of personalized medicine. This shift in treatment paradigms is likely to expand the pegylated drugs market, as more healthcare professionals adopt these innovative therapies to provide customized treatment solutions for patients.

Market Segment Insights

By Molecule: Macromolecular Drugs (Largest) vs. Lipid Nanoparticles (Fastest-Growing)

In the South Korea pegylated drugs market, Macromolecular Drugs hold the largest market share, driven by their advanced therapeutic potentials and efficacy in targeting diseases. This segment benefits from robust research and development investments, leading to a strong foothold in the market. Conversely, Lipid Nanoparticles are emerging rapidly, fueled by increased adoption in mRNA vaccine delivery systems and personalized medicine approaches. Their innovative formulations are expanding therapeutic possibilities, thereby enhancing their attractiveness to pharmaceutical companies. The growth trends in the South Korea pegylated drugs market reflect a shift towards more sophisticated drug delivery systems. Macromolecular Drugs continue to dominate due to their established presence and proven effectiveness. Meanwhile, Lipid Nanoparticles are witnessing accelerated growth as they align with advancements in biopharmaceutical technologies and heightened demand for targeted therapy options. This dynamic landscape is indicative of a transition towards more sophisticated and effective treatments, potentially reshaping patient outcomes in the coming years.

Macromolecular Drugs (Dominant) vs. Liposomes (Emerging)

Macromolecular Drugs represent a dominant force in the South Korea pegylated drugs market with their capacity for complex therapeutic applications and high specificity. These drugs often include biologics and monoclonal antibodies, making them essential in treating various chronic and complex diseases. Their well-established regulatory pathways and substantial investment in R&D reinforce their market position. In contrast, Liposomes are categorized as an emerging segment, gaining traction due to their versatility in encapsulating drugs. They enhance the pharmacokinetics of therapeutics and reduce toxicity, making them especially appealing for cancer and infectious disease treatments. The integration of liposomal formulations in clinical settings is gradually rising, reflecting a broader trend towards innovative drug delivery methods.

By Application: Oncology (Largest) vs. Neurology (Fastest-Growing)

In the South Korea pegylated drugs market, the application segment is primarily dominated by oncology, which captures a significant share due to the increasing prevalence of cancer and the consequent demand for advanced therapeutic options. Other applications, such as neurology and autoimmune diseases, also hold noteworthy positions but lag behind oncology in terms of market share. While oncology remains the foremost application, the growing recognition of pegylated drugs in treating chronic neurological disorders is gradually improving the market standings of other applications. The growth trends within this segment reflect an increasing focus on innovative therapies, particularly in the neurology field, which is currently witnessing rapid advancements and investment. Driving factors for this growth include the rising incidence of neurological disorders and the need for effective long-term treatments. As research continues to unveil the benefits of pegylated drugs, we can expect strengthening market shares and a shifting focus towards emerging segments, especially in terms of available treatment options and patient access.

Oncology (Dominant) vs. Neurology (Emerging)

Oncology remains the dominant application within the South Korea pegylated drugs market, characterized by well-established therapies that effectively leverage the benefits of pegylation to enhance drug delivery and therapeutic efficacy. The substantial investment in oncology research and development has resulted in a robust pipeline of pegylated drugs targeting various cancer types. Conversely, neurology is emerging as a significant sector, driven by advancements in medical research aimed at addressing complex neurological conditions. The growing interest in pegylated formulations for neurological disorders highlights the potential this segment holds. Neurology's expansion is attributed to both heightened awareness and the rise in demand for innovative treatment options, positioning it favorably for future growth.

By Distribution Channel: Hospital Pharmacy (Largest) vs. Online Pharmacy (Fastest-Growing)

In the South Korea pegylated drugs market, Hospital Pharmacy holds a significant portion of the distribution channel, capturing the largest market share among the three key segment values. This channel is preferred due to its proximity to medical professionals and the immediacy of access to prescribed medications, reinforcing its dominance in the sector. Online Pharmacy, while currently smaller in overall market share, has been rapidly growing thanks to the increasing trend toward digital health solutions and more convenient drug purchasing options for consumers. Growth trends in the distribution channels reveal a pronounced shift towards Online Pharmacy, particularly driven by the COVID-19 pandemic that accelerated e-commerce adoption in the healthcare sector. The convenience, increased accessibility, and ongoing digital transformations are propelling Online Pharmacy as the fastest-growing segment. Meanwhile, Hospital Pharmacy is expected to continue its stable growth, driven by existing relationships with healthcare providers and patient trust in traditional pharmacy services.

Hospital Pharmacy (Dominant) vs. Online Pharmacy (Emerging)

Hospital Pharmacy plays a dominant role in the South Korea pegylated drugs market, characterized by its established infrastructure and close ties to healthcare institutions, ensuring a reliable supply chain for pegylated drugs. This channel caters primarily to inpatients and specialty prescriptions, often prioritized for complex therapies. In contrast, Online Pharmacy is emerging as a crucial player, characterized by its adaptability to consumer demands for convenience and the growing acceptance of online prescriptions. This channel leverages technology to reach a broader audience, particularly among younger consumers who favor digital solutions. The competition between these channels highlights an evolving marketplace, where traditional methods are complemented by innovative online services.

Get more detailed insights about South Korea Pegylated Drugs Market

Key Players and Competitive Insights

The pegylated drugs market in South Korea is characterized by a dynamic competitive landscape, driven by innovation, strategic partnerships, and a focus on patient-centric solutions. Major players such as Amgen (US), Roche (CH), and Merck (US) are actively shaping the market through their distinct operational strategies. Amgen (US) emphasizes innovation in drug development, particularly in oncology and chronic disease management, while Roche (CH) focuses on expanding its portfolio through strategic acquisitions and collaborations. Merck (US) is leveraging its strong research capabilities to enhance its pegylated drug offerings, particularly in immunotherapy, thereby contributing to a competitive environment that prioritizes advanced therapeutic solutions.

The business tactics employed by these companies include localizing manufacturing to reduce costs and optimize supply chains, which is crucial in a moderately fragmented market. This competitive structure allows for a diverse range of products and services, with key players influencing market dynamics through their operational efficiencies and strategic initiatives. The collective influence of these companies fosters a robust ecosystem that encourages innovation and responsiveness to market demands.

In October 2025, Roche (CH) announced a strategic partnership with a local biotech firm to enhance its pegylated drug development capabilities. This collaboration is expected to accelerate the introduction of novel therapies tailored to the South Korean market, reflecting Roche's commitment to localized innovation. Such partnerships are likely to enhance Roche's competitive edge by integrating local insights into their product development processes.

In September 2025, Amgen (US) launched a new pegylated formulation aimed at improving patient compliance in chronic disease management. This strategic move not only reinforces Amgen's position in the market but also highlights the growing trend towards patient-centric drug development. By focusing on formulations that enhance usability, Amgen appears to be addressing a critical need in the healthcare landscape, potentially leading to increased market share.

In August 2025, Merck (US) expanded its manufacturing capabilities in South Korea, investing approximately $50 million in a new facility dedicated to the production of pegylated drugs. This expansion is indicative of Merck's long-term commitment to the region and its strategy to enhance supply chain reliability. By increasing local production capacity, Merck is likely to improve its responsiveness to market demands and reduce lead times for product availability.

As of November 2025, current trends in the pegylated drugs market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) in drug development processes. Strategic alliances are becoming more prevalent, as companies recognize the value of collaboration in navigating complex regulatory environments and accelerating innovation. Looking ahead, competitive differentiation is expected to evolve, with a shift from price-based competition towards a focus on technological advancements, innovative solutions, and supply chain reliability. This transition underscores the importance of agility and responsiveness in a rapidly changing market.

Key Companies in the South Korea Pegylated Drugs Market market include

Industry Developments

The South Korea Pegylated Drugs Market has witnessed significant developments, particularly with advancements in biotechnology and a growing focus on chronic disease management. Notably, in July 2023, SK Holdings announced a strategic partnership to enhance their pegylated drug portfolio, aiming to streamline the development process for innovative therapies.

Additionally, in June 2023, Boryung Pharmaceutical marked a milestone with the approval of a new pegylated formulation that addresses unmet medical needs in oncology, further enhancing its market presence.

On the M&A front, in August 2023, Samsung Biologics acquired a minority stake in a research firm specializing in pegylated drug delivery systems, which is poised to bolster its pipeline and R&D capabilities. Market valuation growth has been evident, with companies like Hanmi Pharmaceutical and LG Chem reporting substantial increases in revenue from their pegylated drug sales attributed to rising demand for effective therapies.

Over the past few years, the South Korean government has been actively supporting biotechnology innovations and providing funding, intensifying competition and growth within the pegylated drugs sector.

Future Outlook

South Korea Pegylated Drugs Market Future Outlook

The PEGylated Drugs Market is projected to grow at a 6.25% CAGR from 2024 to 2035, driven by increasing demand for targeted therapies and advancements in drug delivery systems.

New opportunities lie in:

  • Development of personalized pegylated therapies for oncology applications.
  • Expansion of pegylated drug formulations for rare diseases.
  • Investment in advanced manufacturing technologies for cost-effective production.

By 2035, the pegylated drugs market is expected to achieve substantial growth and innovation.

Market Segmentation

South Korea Pegylated Drugs Market Molecule Outlook

  • Macromolecular Drugs
  • Small Molecular Drugs
  • Lipid Nanoparticles (LNP)
  • Liposomes

South Korea Pegylated Drugs Market Application Outlook

  • Oncology
  • Neurology
  • Autoimmune Diseases
  • Rare Haematology
  • Others

South Korea Pegylated Drugs Market Distribution Channel Outlook

  • Hospital Pharmacy
  • Online Pharmacy
  • Retail Pharmacy

Report Scope

MARKET SIZE 2024 379.5(USD Million)
MARKET SIZE 2025 403.22(USD Million)
MARKET SIZE 2035 739.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 6.25% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Amgen (US), Roche (CH), Merck (US), Pfizer (US), Novartis (CH), Bristol-Myers Squibb (US), Eli Lilly (US), AstraZeneca (GB), Gilead Sciences (US)
Segments Covered Molecule, Application, Distribution Channel
Key Market Opportunities Emerging biopharmaceutical innovations enhance efficacy and safety in the pegylated drugs market.
Key Market Dynamics Rising demand for pegylated drugs in South Korea driven by innovative therapies and regulatory support for biopharmaceuticals.
Countries Covered South Korea

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FAQs

What is the expected market size of the South Korea Pegylated Drugs Market in 2024?

The South Korea Pegylated Drugs Market is expected to be valued at 244.8 million USD in 2024.

What is the projected market size for the South Korea Pegylated Drugs Market by 2035?

By the year 2035, the South Korea Pegylated Drugs Market is expected to reach a valuation of 734.4 million USD.

What is the expected compound annual growth rate (CAGR) for the South Korea Pegylated Drugs Market from 2025 to 2035?

The market is anticipated to grow at a CAGR of 10.503% from 2025 to 2035.

Which company is expected to hold a significant share in the South Korea Pegylated Drugs Market?

Key players in the market include SK Holdings, Boryung Pharmaceutical, and Samsung Biologics, among others.

What will the market value for Pegylated protein be in 2035 within South Korea?

The Pegylated protein segment is projected to be valued at 240.0 million USD by 2035.

How much is the Pegylated FAB Fragment market expected to be worth in 2024?

The Pegylated FAB Fragment market is expected to be valued at 60.0 million USD in 2024.

What is the anticipated market size for Pegylated enzymes in South Korea by 2035?

The Pegylated enzyme segment is projected to reach a market size of 210.0 million USD by 2035.

What are the expected market opportunities in the South Korea Pegylated Drugs Market?

The market presents growth opportunities driven by advancements in drug formulations and increasing therapeutic applications.

How much is the Pegylated Aptamer segment expected to be valued by 2035?

The Pegylated Aptamer segment is expected to achieve a market value of 104.4 million USD by 2035.

What is the current trend impacting the South Korea Pegylated Drugs Market?

Emerging trends include increased focus on personalized medicine and its applications in various therapeutic areas.

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