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UK Geographic Atrophy (GA) Market

ID: MRFR/HC/49909-HCR
200 Pages
Garvit Vyas
October 2025

UK Geographic Atrophy GA Market Research Report By Age Group (Above 60 Years, Above 75 Years), By Diagnosis (Fundus Autofluorescence, Optical Coherence Tomography Angiography, Multifocal Electroretinography) andBy Therapeutic Agents Clinical Phase (Late-Stage, Phase II, Phase I, Pre-Clinical Stage, Discovery Candidates)- Forecast to 2035

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UK Geographic Atrophy (GA) Market Infographic
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UK Geographic Atrophy (GA) Market Summary

As per MRFR analysis, the UK geographic atrophy-ga market Size was estimated at 1739.48 USD Million in 2024. The UK geographic atrophy-ga market is projected to grow from 1870.46 USD Million in 2025 to 3865.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 7.53% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The UK geographic atrophy market is poised for growth driven by demographic shifts and technological advancements.

  • The rising prevalence of age-related macular degeneration (AMD) is significantly influencing the geographic atrophy market.
  • Advancements in diagnostic technologies are enhancing early detection and management of geographic atrophy.
  • The largest segment in the UK market is the treatment segment, while the fastest-growing segment is the diagnostic segment.
  • Key market drivers include the increasing aging population and rising healthcare expenditure, which are likely to propel market growth.

Market Size & Forecast

2024 Market Size 1739.48 (USD Million)
2035 Market Size 3865.0 (USD Million)
CAGR (2025 - 2035) 7.53%

Major Players

Novartis (CH), Regeneron Pharmaceuticals (US), Roche (CH), Bayer (DE), Alcon (CH), Apellis Pharmaceuticals (US), Santen Pharmaceutical (JP), Horizon Therapeutics (IE)

UK Geographic Atrophy (GA) Market Trends

The geographic atrophy-ga market is currently experiencing notable developments, driven by an increasing prevalence of age-related macular degeneration (AMD) among the aging population. This condition, characterized by the progressive degeneration of retinal cells, leads to significant vision impairment. As the demographic landscape shifts, healthcare providers and pharmaceutical companies are focusing on innovative treatment options. The rise of advanced diagnostic technologies is also contributing to early detection, which is crucial for effective management of the disease. Furthermore, the regulatory environment is evolving, with authorities emphasizing the need for rigorous clinical trials to ensure safety and efficacy of new therapies. In addition, patient awareness and education regarding geographic atrophy are on the rise, which may lead to earlier consultations with healthcare professionals. This trend is likely to enhance the demand for specialized care and treatment options. The market appears poised for growth, as stakeholders invest in research and development to address unmet needs. Overall, the geographic atrophy-ga market is navigating a complex landscape, with opportunities for innovation and improved patient outcomes. The interplay of demographic changes, technological advancements, and regulatory frameworks will shape the future of this market.

Rising Prevalence of AMD

The increasing incidence of age-related macular degeneration is a key driver in the geographic atrophy-ga market. As the population ages, more individuals are likely to develop this condition, leading to heightened demand for effective treatments and management strategies.

Advancements in Diagnostic Technologies

Innovations in diagnostic tools are enhancing the ability to detect geographic atrophy at earlier stages. These advancements facilitate timely intervention, which is crucial for preserving vision and improving patient quality of life.

Regulatory Changes and Clinical Trials

The evolving regulatory landscape is influencing the geographic atrophy-ga market. Authorities are placing greater emphasis on the necessity of comprehensive clinical trials, which may impact the approval process for new therapies and treatments.

UK Geographic Atrophy (GA) Market Drivers

Increasing Aging Population

The demographic shift towards an older population in the UK is a primary driver for the geographic atrophy-ga market. As individuals age, the risk of developing age-related macular degeneration (AMD) increases significantly. Current estimates suggest that approximately 1.5 million people in the UK are affected by AMD, with a notable portion progressing to geographic atrophy. This growing patient population necessitates enhanced healthcare services and treatment options, thereby stimulating market growth. The geographic atrophy-ga market is likely to see increased demand for innovative therapies and management strategies tailored to this aging demographic. Furthermore, the rising awareness of eye health among older adults may lead to earlier diagnosis and intervention, further propelling market expansion.

Rising Healthcare Expenditure

The increasing allocation of resources towards healthcare in the UK is a significant driver for the geographic atrophy-ga market. Government spending on health services has been on the rise, with a focus on improving access to treatments for chronic conditions, including AMD. In 2025, healthcare expenditure is projected to reach approximately £200 billion, reflecting a commitment to enhancing patient care. This financial support is likely to facilitate the development and distribution of new therapies within the geographic atrophy-ga market. Additionally, as healthcare providers invest in advanced diagnostic tools and treatment options, patients may benefit from improved access to care, ultimately driving market growth.

Growing Awareness and Education

There is a notable increase in public awareness and education regarding eye health and conditions such as geographic atrophy in the UK. Campaigns aimed at educating the population about the risks and symptoms of AMD are becoming more prevalent, leading to earlier detection and treatment. This heightened awareness is likely to result in a larger patient base seeking medical advice and intervention, thereby expanding the geographic atrophy-ga market. Furthermore, healthcare professionals are increasingly prioritizing patient education, which may empower individuals to take proactive steps in managing their eye health. As a result, the market could experience a surge in demand for both diagnostic and therapeutic solutions.

Technological Innovations in Treatment

Recent advancements in treatment modalities for geographic atrophy are poised to transform the geographic atrophy-ga market. Innovative therapies, including gene therapy and novel pharmacological agents, are under investigation and show promise in slowing disease progression. The UK has seen a surge in clinical trials focusing on these cutting-edge treatments, with several candidates demonstrating efficacy in preliminary studies. For instance, the market could witness the introduction of therapies that target specific pathways involved in retinal degeneration. As these innovations gain traction, they may not only enhance patient outcomes but also attract investment into the geographic atrophy-ga market, fostering a competitive landscape that encourages further research and development.

Regulatory Support for Innovative Therapies

The regulatory environment in the UK is becoming increasingly supportive of innovative therapies for geographic atrophy. Regulatory bodies are streamlining the approval processes for new treatments, which may encourage pharmaceutical companies to invest in research and development. This trend is particularly relevant as the geographic atrophy-ga market seeks to introduce novel therapies that address unmet medical needs. The UK government has also initiated programs aimed at expediting access to breakthrough therapies, which could significantly impact market dynamics. As a result, the geographic atrophy-ga market may witness a faster introduction of effective treatments, ultimately benefiting patients and healthcare providers alike.

Market Segment Insights

By Age Group: Above 60 Years (Largest) vs. Above 75 Years (Fastest-Growing)

In the UK geographic atrophy-ga market, the age group of individuals above 60 years holds the largest market share, reflecting the increasing prevalence of age-related eye conditions in this demographic. This group is significantly impacted by geographic atrophy, leading to a higher demand for treatment options and supportive care. Meanwhile, the segment of individuals above 75 years is rapidly gaining traction, driven by the rising life expectancy and the subsequent growth of elderly populations requiring specialized care for geographic atrophy. The growth trends for this segment indicate a pronounced shift towards more targeted therapies and personalized care solutions as the population ages. The increasing awareness of eye health and the willingness of older adults to seek medical interventions contribute to the expansion of the market. Furthermore, advancements in treatment methodologies and support systems for the elderly are poised to strengthen this market segment, highlighting their critical role in the overall health landscape of the UK.

Above 60 Years (Dominant) vs. Above 75 Years (Emerging)

The segment of individuals above 60 years is characterized by a long-established presence in the UK geographic atrophy-ga market, largely due to the high incidence of age-related macular degeneration and other retinal diseases prevalent in this age group. Their dominance is supported by a well-developed network of healthcare providers and a growing range of treatment options tailored to their needs. Conversely, the emerging segment of those above 75 years is gaining prominence, reflecting a dynamic shift as healthcare systems adapt to cater to the unique challenges faced by this older cohort. This group often experiences a more severe impact from geographic atrophy, necessitating innovative therapeutic approaches and more intensive management strategies.

By Diagnosis: Fundus Autofluorescence (Largest) vs. Optical Coherence Tomography Angiography (Fastest-Growing)

In the UK geographic atrophy-ga market, the diagnosis segment is primarily dominated by Fundus Autofluorescence (FAF), which has the largest market share. This non-invasive imaging technique is critical for assessing retinal health and detecting geographic atrophy effectively. Following FAF, Optical Coherence Tomography Angiography (OCT-A) is rapidly gaining traction due to its advanced imaging capabilities that allow detailed visualization of retinal vasculature, making it essential for diagnosis. Growth trends indicate a strong shift towards technologies that enhance diagnostic accuracy. The increasing prevalence of geographic atrophy in the aging population drives the demand for advanced diagnostic methods. Innovations like OCT-A's real-time imaging and the non-invasive nature of FAF contribute significantly to their adoption, highlighting the market's dynamic evolution toward more efficient and effective diagnostic solutions.

Fundus Autofluorescence (Dominant) vs. Optical Coherence Tomography Angiography (Emerging)

Fundus Autofluorescence (FAF) stands out as the dominant diagnostic technique in the UK geographic atrophy-ga market, renowned for its ability to visualize the distribution of lipofuscin in retinal pigment epithelium. Its efficiency in detecting early signs of geographic atrophy makes it invaluable for timely intervention. In contrast, Optical Coherence Tomography Angiography (OCT-A) is an emerging technology that offers detailed insights into retinal blood flow without requiring dye injection. This innovative approach is gaining momentum among healthcare professionals due to its precision and ability to improve patient outcomes. As awareness and technology advance, both FAF and OCT-A are poised to play pivotal roles in enhancing diagnostic capabilities within the market.

By Therapeutic Agents Clinical Phase: Late-Stage (Largest) vs. Phase II (Fastest-Growing)

The therapeutic agents clinical phase segment in the UK geographic atrophy-ga market is characterized by varying market shares across different developmental stages. Late-stage (Phase III) agents capture the largest market share due to their advanced development and the imminent potential for approval. Phase II agents show significant promise, gradually capturing attention as their clinical efficacy becomes more established, though they remain in a comparatively smaller share of the market. Growth trends in this segment are influenced by heightened research and development investments, driving the advancement of new therapies. The push for innovative treatments to address geographic atrophy has resulted in accelerated clinical trials and increased partnerships between pharmaceutical companies and research institutions. This momentum positions Phase II agents as the fastest-growing segment, as they showcase strong pipeline potential and attract investor interest, highlighting the dynamic nature of this market area.

Late-Stage (Dominant) vs. Phase II (Emerging)

Late-stage (Phase III) therapeutic agents are currently the dominant force in the UK geographic atrophy-ga market, reflecting a wealth of clinical data and nearing commercialization. These agents benefit from extensive research backing, solidifying their position with healthcare providers and payers due to proven efficacy and safety profiles. In contrast, Phase II agents are emerging as significant contenders, showcasing early efficacy data and the potential for innovative treatments. These agents are often seen as the next wave of therapeutic options, possessing characteristics that may lead to favorable outcomes. As they progress through clinical trials, interest from stakeholders is anticipated to increase, making Phase II a vital segment for future developments in the therapeutic landscape.

Get more detailed insights about UK Geographic Atrophy (GA) Market

Key Players and Competitive Insights

The geographic atrophy-ga market is characterized by a competitive landscape that is increasingly shaped by innovation and strategic partnerships. Key players such as Novartis (CH), Regeneron Pharmaceuticals (US), and Roche (CH) are actively pursuing strategies that emphasize research and development, aiming to enhance their product offerings and market presence. Novartis (CH) has focused on expanding its portfolio through collaborations, while Regeneron Pharmaceuticals (US) is leveraging its expertise in biologics to develop novel therapies. Roche (CH) appears to be concentrating on integrating digital health solutions into its treatment paradigms, thereby enhancing patient engagement and outcomes. Collectively, these strategies contribute to a dynamic environment where innovation is paramount, and companies are vying for leadership through differentiated offerings.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and responsiveness to market demands. The competitive structure of the market is moderately fragmented, with several players holding significant shares, yet none dominating entirely. This fragmentation allows for a variety of approaches to treatment and patient care, fostering a competitive atmosphere where collaboration and innovation are essential for success.

In October 2025, Novartis (CH) announced a strategic partnership with a leading digital health firm to develop a comprehensive platform aimed at improving patient adherence to geographic atrophy treatments. This move is significant as it not only enhances Novartis's product offering but also positions the company at the forefront of integrating technology into healthcare, potentially improving patient outcomes and satisfaction.

In September 2025, Regeneron Pharmaceuticals (US) reported the initiation of a pivotal clinical trial for a new therapy targeting geographic atrophy. This trial is crucial as it underscores Regeneron's commitment to advancing treatment options and reflects the company's strategy to leverage its robust R&D capabilities. The outcome of this trial could significantly influence the competitive landscape, particularly if the therapy demonstrates superior efficacy.

In August 2025, Roche (CH) launched a new digital tool designed to assist healthcare providers in monitoring patients with geographic atrophy. This initiative highlights Roche's focus on digital transformation and its potential to enhance the standard of care. By providing healthcare professionals with advanced tools, Roche aims to solidify its position as a leader in patient-centric solutions.

As of November 2025, the competitive trends in the geographic atrophy-ga market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence. Strategic alliances are becoming more prevalent, as companies recognize the value of collaboration in driving innovation. Looking ahead, it is likely that competitive differentiation will evolve, shifting from traditional price-based competition to a focus on technological advancements, innovative therapies, and reliable supply chains. This transition may redefine how companies engage with healthcare providers and patients, ultimately shaping the future of the market.

Key Companies in the UK Geographic Atrophy (GA) Market market include

Industry Developments

The UK Geographic Atrophy (GA) market has seen significant developments in recent months. Horizon Therapeutics and Apellis Pharmaceuticals are actively involved in advancing therapies aimed at treating GA, with Apellis continuing to gain traction for its innovative complement inhibition approach. Furthermore, Novartis has recently expanded its research footprint in the UK to enhance its ocular portfolio related to retinal diseases.

In terms of mergers and acquisitions, there have been no widely reported engagements involving the companies of specific interest in the UK market. Growth in market valuation has been observed, particularly with companies such as Regeneron Pharmaceuticals and Sobi, which are focusing on expanding their Research and Development efforts in the GA domain. The UK has observed a rising prevalence of GA, prompting a greater emphasis on early diagnosis and potential therapies. Over the past few years, developments in gene therapy through Iovance Biotherapeutics and others significant attention in the research environments of UK healthcare institutions.

These advancements contribute to a dynamic and evolving landscape for Geographic Atrophy treatment solutions in the UK.

Future Outlook

UK Geographic Atrophy (GA) Market Future Outlook

The Geographic Atrophy GA Market is projected to grow at a 7.53% CAGR from 2024 to 2035, driven by increasing prevalence and advancements in treatment options.

New opportunities lie in:

  • Development of targeted gene therapies for geographic atrophy
  • Expansion of telemedicine platforms for remote patient monitoring
  • Investment in AI-driven diagnostic tools for early detection

By 2035, the market is expected to achieve substantial growth, driven by innovative treatment solutions.

Market Segmentation

UK Geographic Atrophy (GA) Market Age Group Outlook

  • Above 60 Years
  • Above 75 Years

UK Geographic Atrophy (GA) Market Diagnosis Outlook

  • Fundus Autofluorescence (FAF)
  • Optical Coherence Tomography Angiography (OCT-A)
  • Multifocal Electroretinography (MfERG)

UK Geographic Atrophy (GA) Market Therapeutic Agents Clinical Phase Outlook

  • Late-Stage (Phase III)
  • Phase II
  • Phase I
  • Pre-Clinical Stage & Discovery Candidates

Report Scope

MARKET SIZE 2024 1739.48(USD Million)
MARKET SIZE 2025 1870.46(USD Million)
MARKET SIZE 2035 3865.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 7.53% (2024 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Novartis (CH), Regeneron Pharmaceuticals (US), Roche (CH), Bayer (DE), Alcon (CH), Apellis Pharmaceuticals (US), Santen Pharmaceutical (JP), Horizon Therapeutics (IE)
Segments Covered Age Group, Diagnosis, Therapeutic Agents Clinical Phase
Key Market Opportunities Advancements in gene therapy and digital health solutions enhance treatment options in the geographic atrophy-ga market.
Key Market Dynamics Rising demand for innovative therapies drives competition and regulatory scrutiny in the geographic atrophy market.
Countries Covered UK

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FAQs

What is the estimated market size of the UK Geographic Atrophy GA Market in 2024?

The UK Geographic Atrophy GA Market is expected to be valued at 1.75 billion USD in 2024.

What is the projected market size for the UK Geographic Atrophy GA Market by 2035?

By 2035, the overall market is projected to reach a value of 3.0 billion USD.

What is the expected compound annual growth rate (CAGR) for the UK Geographic Atrophy GA Market from 2025 to 2035?

The market is expected to grow at a CAGR of 5.022% during the forecast period from 2025 to 2035.

Which age group holds the largest market share within the UK Geographic Atrophy GA Market?

The age group above 60 years holds a significant market share, with a value of 1.05 billion USD in 2024.

What is the market size for the above 75 years age group in the UK Geographic Atrophy GA Market for 2024?

For the above 75 years age group, the market is valued at 0.7 billion USD in 2024.

Who are the key players in the UK Geographic Atrophy GA Market?

Major players in the market include Horizon Therapeutics, Apellis Pharmaceuticals, and Novartis among others.

What is the market value for the above 60 years age group by 2035?

By 2035, the market value for the above 60 years age group is anticipated to reach 1.75 billion USD.

What is the projected market value for the above 75 years age group by 2035?

The expected market value for the above 75 years age group is projected at 1.25 billion USD in 2035.

What are the growth drivers for the UK Geographic Atrophy GA Market?

The primary growth drivers include increasing prevalence of age-related diseases and advancements in treatment options.

How do current global trends affect the UK Geographic Atrophy GA Market?

Current global trends and conflicts may impact supply chains and regulatory environments affecting market growth.

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