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UK Organ On Chip Market

ID: MRFR/MED/49549-HCR
200 Pages
Garvit Vyas
October 2025

UK Organ-on-Chip Market Research Report: By Organ Type (Lung-on-Chip, Heart-on-Chip, Liver-on-Chip, Intestine-on-Chip, Kidney-on-Chip, Human-on-Chip), By Application (Drug Discovery, Toxicology Research, Others) andBy End-User (Pharmaceutical Companies, Research Organizations, Others)- Forecast to 2035

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UK Organ On Chip Market Infographic
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UK Organ On Chip Market Summary

As per MRFR analysis, the UK organ on-chip market size was estimated at 20.53 USD Million in 2024. The UK organ on-chip market is projected to grow from 21.86 USD Million in 2025 to 41.05 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 6.5% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The UK organ on-chip market is poised for substantial growth driven by technological advancements and regulatory support.

  • Technological advancements in microfabrication techniques are enhancing the capabilities of organ on-chip systems.
  • The largest segment in the UK market is expected to be the pharmaceutical industry, while the fastest-growing segment is likely to be personalized medicine.
  • Regulatory support is fostering collaborative research initiatives, which are crucial for market expansion.
  • Rising demand for personalized medicine and increased investment in biotech research are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 20.53 (USD Million)
2035 Market Size 41.05 (USD Million)

Major Players

Emulate Inc (US), Mimetas (NL), TissUse (DE), Organovo Holdings Inc (US), Synlogic Inc (US), Hesperos Inc (US), InSphero AG (CH), Reinnervate Ltd (GB)

UK Organ On Chip Market Trends

the organ on-chip market is experiencing notable growth, driven by advancements in biotechnology and increasing demand for innovative drug testing methods. This technology mimics human organ functions, allowing researchers to conduct experiments in a more accurate and ethical manner. The shift towards personalized medicine is also influencing the market, as organ on-chip systems can provide insights tailored to individual patient profiles. Furthermore, regulatory bodies are beginning to recognize the potential of these systems, which may lead to increased funding and support for research and development initiatives. In addition, collaborations between academic institutions and industry players are becoming more prevalent, fostering innovation and accelerating the adoption of organ on-chip technologies. The focus on reducing animal testing and improving the efficiency of drug discovery processes is likely to further propel market growth. As the organ on-chip market continues to evolve, it appears poised to play a crucial role in the future of medical research and therapeutic development, potentially transforming how treatments are developed and tested.

Technological Advancements

Recent innovations in microfabrication and materials science are enhancing the capabilities of organ on-chip systems. These advancements allow for more complex and functional models that better replicate human physiology, which is essential for accurate drug testing and disease modeling.

Regulatory Support

There is a growing recognition among regulatory agencies of the value that organ on-chip technologies bring to the field of drug development. This support may lead to streamlined approval processes and increased funding opportunities for research initiatives.

Collaborative Research Initiatives

Partnerships between universities, research institutions, and industry stakeholders are becoming increasingly common. These collaborations aim to leverage diverse expertise and resources, driving innovation and accelerating the commercialization of organ on-chip technologies.

UK Organ On Chip Market Drivers

Growing Awareness of Ethical Concerns

Ethical considerations surrounding animal testing are increasingly influencing the organ on-chip market. As public awareness of animal welfare issues rises, there is a growing demand for alternative testing methods that do not rely on animal models. The organ on-chip technology presents a viable solution, offering a more humane approach to drug testing and development. This shift in consumer sentiment is prompting pharmaceutical companies and research institutions in the UK to adopt organ-on-chip systems as part of their testing protocols. The organ on-chip market is likely to benefit from this trend, as stakeholders seek to align their practices with ethical standards. Furthermore, regulatory bodies are beginning to recognize the potential of these technologies, which may lead to more favorable guidelines and support for their adoption. This evolving landscape suggests a promising future for the organ on-chip market as it aligns with societal values.

Rising Demand for Personalized Medicine

The organ on-chip market is experiencing a notable surge in demand for personalized medicine solutions. As healthcare shifts towards tailored treatments, the need for advanced models that mimic human physiology becomes critical. This market driver is underscored by the increasing prevalence of chronic diseases in the UK, which necessitates innovative drug testing and development methods. The organ on-chip technology offers a promising alternative to traditional animal testing, providing more accurate predictions of human responses. According to recent estimates, the organ on-chip market is projected to grow at a CAGR of approximately 25% over the next five years, reflecting the growing interest in personalized therapeutic approaches. This trend indicates a significant opportunity for stakeholders in the organ on-chip market to develop solutions that cater to the specific needs of patients, thereby enhancing treatment efficacy and safety.

Increased Investment in Biotech Research

Investment in biotechnology research is a pivotal driver for the organ on-chip market. The UK government and private sector are increasingly allocating funds to support innovative research initiatives aimed at developing advanced organ-on-chip technologies. This influx of capital is expected to accelerate the development of sophisticated models that can replicate human organ functions more accurately. Recent reports suggest that the UK biotech sector has seen an investment increase of over £1 billion in the last year alone, with a significant portion directed towards organ-on-chip research. This financial backing not only fosters innovation but also encourages collaboration between academic institutions and industry players, thereby enhancing the overall growth of the organ on-chip market. As research progresses, the potential applications of these technologies in drug discovery and disease modeling are likely to expand, further driving market demand.

Advancements in Microfabrication Techniques

The organ on-chip market is being propelled by advancements in microfabrication techniques, which enable the creation of more complex and functional organ models. Innovations in materials science and engineering are allowing researchers to develop chips that closely mimic the architecture and functionality of human organs. These advancements are crucial for enhancing the predictive power of organ-on-chip systems in drug testing and disease modeling. As microfabrication technologies continue to evolve, the organ on-chip market is expected to expand, with new applications emerging in areas such as toxicology and regenerative medicine. The integration of these advanced techniques is likely to improve the reliability and reproducibility of organ-on-chip experiments, thereby attracting more researchers and companies to invest in this technology. This trend indicates a robust growth trajectory for the organ on-chip market in the coming years.

Regulatory Changes Favoring Innovative Technologies

Regulatory changes in the UK are increasingly favoring the adoption of innovative technologies, including organ-on-chip systems. As regulatory agencies recognize the limitations of traditional testing methods, there is a growing push towards integrating advanced technologies that can provide more reliable data. This shift is likely to create a more conducive environment for the organ on-chip market, as companies seek to comply with evolving regulations while enhancing their research capabilities. Recent initiatives by UK regulatory bodies to streamline approval processes for alternative testing methods suggest a positive outlook for the organ on-chip market. By facilitating the entry of these technologies into the market, regulatory changes may accelerate the development and commercialization of organ-on-chip solutions, ultimately benefiting both researchers and patients.

Market Segment Insights

Organ-on-Chip Market Organ Type Insights

The UK Organ-on-Chip Market is witnessing a transformative phase, particularly within the Organ Type segment, which encompasses innovative technologies such as Lung-on-Chip, Heart-on-Chip, Liver-on-Chip, Intestine-on-Chip, Kidney-on-Chip, and Human-on-Chip models. Each of these platforms plays a vital role in revolutionizing biological studies and pharmaceutical testing by allowing researchers to simulate human organ functions in vitro, leading to more accurate drug responses and disease modeling. The Lung-on-Chip model is particularly significant as it helps in studying respiratory diseases and enables researchers to examine drug effects against lung conditions such as asthma and chronic obstructive pulmonary disease.

This aspect is particularly relevant for the UK, where respiratory health has been a point of focus for public health improvements under government initiatives.

The Heart-on-Chip segment is also crucial, serving to investigate cardiac diseases and evaluate the safety of numerous pharmaceuticals that could impact heart function. Given the growing concern around cardiovascular diseases within the UK, this model notably supports the trend of personalized medicine by facilitating precise drug testing and development. The Liver-on-Chip technology stands out in the context of drug metabolism and toxicity studies, addressing the rising need for safer drug design as the pharmaceutical sector comes under scrutiny for adverse drug reactions.

Considering the prevalence of liver-related disorders in the UK population, this model fosters advancements in understanding liver functions and pathologies.

Moreover, the Intestine-on-Chip model is emerging as a foundational platform for gut microbiome studies, contributing significantly to our comprehension of gastrointestinal diseases and their relation to systemic health. This has a direct linkage to public health policies focusing on improving dietary health and managing conditions like inflammatory bowel disease, thus gaining importance in the UK healthcare conversation. The Kidney-on-Chip platform is essential for renal research, particularly against the backdrop of increasing rates of chronic kidney disease in the UK scene, making it a critical area of investigation for nephrology and drug development.

Organ-on-Chip Market Application Insights

The Application segment of the UK Organ-on-Chip Market plays a crucial role in developing innovative solutions for the pharmaceutical and biotechnology industries. This segment predominantly focuses on Drug Discovery and Toxicology Research, which are essential for evaluating drug efficacy and safety. The growing demand for more accurate preclinical testing models drives the need for Organ-on-Chip technology, as it effectively mimics human organ functions, significantly reducing the reliance on animal testing. Drug Discovery is particularly vital for the UK, which boasts a strong pharmaceutical sector, making the integration of microfluidic technologies increasingly important.

Toxicology Research also stands out, given the stringent regulatory requirements in the UK aimed at ensuring public safety and environmental protection. Moreover, as the industry continues to evolve, there are ample opportunities in both academia and the private sector to leverage Organ-on-Chip technology for advancements in Personalized Medicine and precision therapeutics. The UK government supports innovation in the biotech field, further enhancing the growth potential of the Organ-on-Chip market, characterized by robust relationships between industry, academia, and regulatory bodies.

This collaborative environment fosters the development of advanced models that can transform drug testing processes while addressing the growing demands of healthcare stakeholders.

Organ-on-Chip Market End-User Insights

The UK Organ-on-Chip Market, a rapidly evolving sector, showcases significant engagement from various end-users, including Pharmaceutical Companies, Research Organizations, and Other entities. Pharmaceutical Companies play a crucial role in leveraging organ-on-chip technologies for drug testing and development, enabling them to enhance the efficiency of therapeutic interventions while minimizing costs and time. These companies are increasingly adopting innovative in vitro models that replicate human physiology to better predict drug reactions, thus transforming their Research and Development processes.

Research Organizations also represent a vital component of the UK Organ-on-Chip Market, as they investigate novel applications and refine organ-on-chip systems for diverse biomedical applications. Their contributions not only advance scientific understanding but also promote collaborations with leading manufacturers and academic institutions to drive innovation. Additionally, Other end-users, encompassing academic institutions and regulatory bodies, are crucial for advancing the regulatory frameworks and guidelines governing the application of organ-on-chip technologies. Through these collaborations, the market experiences growth driven by the necessity for more accurate, ethical, and cost-effective alternatives to traditional testing methods.

Overall, the engagement of these end-users underpins the dynamic evolution of the UK Organ-on-Chip Market, fostering advancements that promise significant impacts across healthcare and pharmaceutical landscapes.

Get more detailed insights about UK Organ On Chip Market

Key Players and Competitive Insights

The organ on-chip market is currently characterized by a dynamic competitive landscape, driven by advancements in biotechnology and increasing demand for more efficient drug testing methods. Key players such as Emulate Inc (US), Mimetas (NL), and TissUse (DE) are at the forefront, each adopting distinct strategies to enhance their market positioning. Emulate Inc (US) focuses on innovation through the development of advanced organ-on-chip platforms that mimic human physiology, thereby improving the accuracy of drug testing. Meanwhile, Mimetas (NL) emphasizes partnerships with pharmaceutical companies to expand its reach and application of its organ-on-chip technology, which appears to be a strategic move to solidify its market presence. TissUse (DE) is also notable for its commitment to regional expansion, particularly in Europe, which suggests a strategy aimed at capturing a larger share of the growing demand for organ-on-chip solutions.

The business tactics employed by these companies reflect a moderately fragmented market structure, where localized manufacturing and supply chain optimization are becoming increasingly vital. The collective influence of these key players indicates a competitive environment that is not only shaped by technological advancements but also by strategic collaborations and partnerships that enhance operational capabilities. This fragmentation allows for a diverse range of innovations, although it also necessitates a keen focus on efficiency and cost-effectiveness to maintain competitive advantage.

In October 2025, Emulate Inc (US) announced a collaboration with a leading pharmaceutical company to develop a new organ-on-chip model that simulates the human liver. This strategic partnership is likely to enhance Emulate's product offerings and could significantly accelerate the drug development process, thereby positioning the company as a leader in the market. The implications of this collaboration suggest a potential shift in how drug testing is conducted, moving towards more personalized and accurate methodologies.

In September 2025, Mimetas (NL) launched a new organ-on-chip platform designed specifically for cancer research, which could revolutionize the way oncological therapies are tested. This innovation not only underscores Mimetas's commitment to addressing critical healthcare challenges but also highlights its strategic focus on niche markets within the organ-on-chip sector. The introduction of this platform may attract significant interest from research institutions and pharmaceutical companies, further solidifying Mimetas's competitive edge.

In August 2025, TissUse (DE) secured a substantial investment to enhance its manufacturing capabilities, which is indicative of its strategy to scale operations and meet the increasing demand for organ-on-chip technologies. This investment is expected to bolster TissUse's production efficiency and expand its product line, thereby enhancing its competitive positioning in the market. The focus on scaling operations aligns with the broader trend of companies seeking to optimize their supply chains in response to growing market demands.

As of November 2025, the organ on-chip market is witnessing trends that emphasize digitalization, sustainability, and the integration of artificial intelligence. These trends are reshaping the competitive landscape, as companies increasingly seek strategic alliances to leverage technological advancements and enhance their product offerings. The shift from price-based competition to a focus on innovation and technology is becoming evident, suggesting that future competitive differentiation will hinge on the ability to deliver reliable, cutting-edge solutions that meet the evolving needs of the healthcare sector.

Key Companies in the UK Organ On Chip Market market include

Industry Developments

The UK Organ-on-Chip Market has continued to experience significant developments recently. Companies like Mimetas and Hesperos are advancing their platforms for high-throughput drug testing, focusing on creating more accurate disease models. In July 2023, TissUse announced a partnership with Regenhu to enhance tissue engineering workflows, further validating collaborations across the sector. Acelity has contributed to advancing wound care applications within the Organ-on-Chip context. Market valuations have seen an upswing, with Biolife Solutions noting a substantial increase in demand for its biopreservation products utilized in Organ-on-Chip technologies, reflecting a heightened interest in innovative healthcare solutions.

Emulate is pushing boundaries with its latest organ models, gaining traction among pharmaceutical companies for drug discovery. The last couple of years have also seen major milestones, such as Organovo's increased focus on commercialization strategies in September 2022, alongside Stratec's advancements in automated systems for Organ-on-Chip platforms. Current outlooks suggest robust growth, propelled by rising investment and government support for biotechnology initiatives in the UK.

Future Outlook

UK Organ On Chip Market Future Outlook

The organ on-chip market is projected to grow at a 6.5% CAGR from 2024 to 2035, driven by advancements in biotechnology, regulatory support, and increasing demand for personalized medicine.

New opportunities lie in:

  • Development of customizable organ-on-chip platforms for specific disease models.
  • Partnerships with pharmaceutical companies for drug testing applications.
  • Integration of AI for predictive analytics in organ-on-chip systems.

By 2035, the organ on-chip market is expected to achieve substantial growth and innovation.

Market Segmentation

UK Organ On Chip Market End-User Outlook

  • Pharmaceutical Companies
  • Research Organizations
  • Others

UK Organ On Chip Market Organ Type Outlook

  • Lung-on-Chip
  • Heart-on-Chip
  • Liver-on-Chip
  • Intestine-on-Chip
  • Kidney-on-Chip
  • Skin-on-Chip
  • Blood-Brain Barrier-on-Chip
  • Human-on-Chip

UK Organ On Chip Market Application Outlook

  • Drug Discovery
  • Toxicology Research
  • Others

Report Scope

MARKET SIZE 202420.53(USD Million)
MARKET SIZE 202521.86(USD Million)
MARKET SIZE 203541.05(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)6.5% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Emulate Inc (US)", "Mimetas (NL)", "TissUse (DE)", "Organovo Holdings Inc (US)", "Synlogic Inc (US)", "Hesperos Inc (US)", "InSphero AG (CH)", "Reinnervate Ltd (GB)"]
Segments CoveredOrgan Type, Application, End-User
Key Market OpportunitiesAdvancements in organ-on-chip technology enhance drug testing efficiency and regulatory compliance in the UK.
Key Market DynamicsRising demand for organ-on-chip technologies driven by regulatory shifts and advancements in personalized medicine.
Countries CoveredUK

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FAQs

What is the expected market size of the UK Organ-on-Chip Market in 2024?

The UK Organ-on-Chip Market is expected to be valued at 4.51 million USD in 2024.

What is the projected market value for the UK Organ-on-Chip Market by 2035?

By 2035, the UK Organ-on-Chip Market is projected to reach a value of 19.23 million USD.

What is the expected compound annual growth rate (CAGR) for the UK Organ-on-Chip Market from 2025 to 2035?

The expected CAGR for the UK Organ-on-Chip Market from 2025 to 2035 is 14.084%.

Which organ types are expected to lead the UK Organ-on-Chip Market?

Organ types such as Lung-on-Chip, Heart-on-Chip, and Liver-on-Chip are expected to lead the market in the upcoming years.

What are the expected values for Lung-on-Chip in 2024 and 2035?

Lung-on-Chip is expected to be valued at 0.984 million USD in 2024 and 4.164 million USD by 2035.

Who are the key players in the UK Organ-on-Chip Market?

Key players in this market include Mimetas, Hesperos, TissUse, and Organovo among others.

What is the anticipated market value for Liver-on-Chip by 2035?

The market value for Liver-on-Chip is anticipated to reach 4.482 million USD by 2035.

How is the Intestine-on-Chip segment expected to perform in terms of market value?

The Intestine-on-Chip segment is expected to be valued at 0.746 million USD in 2024 and grow to 3.141 million USD by 2035.

What growth opportunities exist in the UK Organ-on-Chip Market?

Growth opportunities in the UK Organ-on-Chip Market include advancements in organ modeling technology and increased demand for drug testing alternatives.

How does the Kidney-on-Chip segment compare in market value from 2024 to 2035?

The Kidney-on-Chip segment is valued at 0.812 million USD in 2024 and is projected to reach 3.562 million USD by 2035.

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