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US Acute Coronary Syndrome Market Research Report By Type (Unstable Angina, Nstemi) and By Diagnosis (Blood Tests, Imaging, Stress Test) - Forecast to 2035


ID: MRFR/Pharma/17376-HCR | 100 Pages | Author: Garvit Vyas| December 2023

US Acute Coronary Syndrome Market Overview


As per MRFR analysis, the US Acute Coronary Syndrome Market Size was estimated at 1.47 (USD Billion) in 2023. The US Acute Coronary Syndrome Market Industry is expected to grow from 1.65 (USD Billion) in 2024 to 4 (USD Billion) by 2035. The US Acute Coronary Syndrome Market CAGR (growth rate) is expected to be around 8.383% during the forecast period (2025 - 2035).


Key US Acute Coronary Syndrome Market Trends Highlighted


The US Acute Coronary Syndrome Market is witnessing significant trends driven by several factors. An increase in the prevalence of risk factors such as obesity, diabetes, and hypertension is a major driver affecting the market. The aging population in the United States also contributes to higher rates of acute coronary syndrome, prompting a greater demand for effective diagnostic and therapeutic solutions. Furthermore, advancements in medical technology are enhancing treatment options, supporting safer and more effective interventions that improve patient outcomes.


Opportunities to be explored in this market revolve around innovation in drug development and the emergence of minimally invasive procedures. Biologics and novel cardiovascular drugs can be leveraged to address the needs of diverse patient populations, including those with complex comorbidities. Additionally, the shift towards personalized medicine allows for tailored treatments that can improve adherence and efficacy, representing a significant growth avenue for companies operating in this space.


Trends in recent times indicate a greater emphasis on preventive care and early intervention strategies in the US, as more healthcare providers adopt integrated approaches to manage patient health. Collaborative care models that involve multiple healthcare disciplines are increasingly prevalent, aiming to reduce the risk of acute coronary events and improve overall cardiovascular health. This trend reflects a growing awareness of the need for comprehensive management of cardiovascular conditions, aligning with the goals of public health initiatives focused on reducing heart disease morbidity and mortality rates across the nation. Overall, these trends and drivers highlight a dynamic and evolving landscape in the US Acute Coronary Syndrome Market.


US Acute Coronary Syndrome Market size

Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


US Acute Coronary Syndrome Market Drivers


Increasing Prevalence of Cardiovascular Diseases


In the United States, cardiovascular diseases, including Acute Coronary Syndrome, are among the leading causes of death. According to the American Heart Association, approximately 697,000 Americans died from heart disease in 2020, highlighting a significant and concerning trend. The increase in obesity rates, which have been reported by the Centers for Disease Control and Prevention (CDC) to affect more than 42% of the US adult population, is a major contributing factor to the rise in cardiovascular diseases.


As the prevalence of these diseases continues to escalate, driven by lifestyle factors such as poor diet, lack of physical activity, and increased stress levels, there is a growing demand for effective treatments and management strategies within the US Acute Coronary Syndrome Market Industry. Established organizations like the American Heart Association are advocating for preventive measures and better healthcare interventions, which further supports the market growth.


Advancements in Diagnostic Technologies


The US Acute Coronary Syndrome Market Industry is significantly benefiting from advancements in diagnostic technologies. Recent innovations, such as high-sensitivity troponin tests and advanced imaging techniques, have improved early detection and diagnosis of Acute Coronary Syndrome. The Centers for Medicare & Medicaid Services (CMS) reported that investments in new laboratory tests have increased diagnostic accuracy by up to 90%, potentially leading to timely and more effective treatment options.


These advancements have garnered attention from several established medical organizations, including the American College of Cardiology, which emphasizes the importance of rapid diagnosis in improving patient outcomes. As technology continues to evolve, the market is projected to grow due to increased demand for these sophisticated diagnostic tools.


Government Initiatives to Improve Heart Health


The US government has launched various initiatives aimed at reducing the burden of heart disease, thus positively impacting the US Acute Coronary Syndrome Market Industry. Programs like the Million Hearts initiative, which aims to prevent 1 million heart attacks and strokes over five years, have spurred growth in cardiovascular health awareness and management. The Office of Disease Prevention and Health Promotion states that these initiatives are crucial for targeting at-risk populations and encouraging lifestyle changes.


Moreover, support from organizations like the National Heart, Lung, and Blood Institute enhances public health efforts, leading to increased funding for research and community health projects. This government focus is foundational in driving market growth through improved healthcare access and awareness.


Rise in Aging Population


The aging population in the United States is a significant driver of the US Acute Coronary Syndrome Market Industry. By 2030, it is projected that 1 in 5 Americans will be 65 years or older, according to the U.S. Census Bureau. This demographic shift is critical as older adults are at higher risk for heart conditions, including Acute Coronary Syndrome. The increase in life expectancy combined with a growing elderly population necessitates advancements in cardiac care and treatments, resulting in escalated demand within the market.


Established healthcare organizations are adapting their strategies to meet the unique needs of older patients, which is expected to enhance treatment accessibility and efficacy, further supporting industry growth.


US Acute Coronary Syndrome Market Segment Insights


Acute Coronary Syndrome Market Type Insights


The US Acute Coronary Syndrome Market is extensively categorized based on Type, reflecting crucial clinical presentations such as Unstable Angina and Non-ST-Elevation Myocardial Infarction (NSTEMI). This categorization is vital for healthcare professionals to tailor treatment approaches effectively, as these conditions present varying levels of risk and urgency. Unstable Angina, characterized by sudden chest pain that may occur at rest, represents a significant area of focus due to its unpredictable nature and association with imminent myocardial infarction, making timely diagnosis and intervention essential. NSTEMI, on the other hand, signifies a type of heart attack where the blood flow to the heart is blocked intermittently, yet not entirely, allowing for potential damage without the classic full-blown symptoms. 


This market segmentation taps into the complexity of patient needs, enabling targeted therapies and interventions that can greatly enhance patient outcomes. Additionally, both Unstable Angina and NSTEMI are on the rise in the US, driven by an increase in risk factors such as obesity, diabetes, and sedentary lifestyles, making early detection and appropriate response crucial in saving lives and reducing healthcare costs. The importance of these classifications is further underscored as they inform the urgent care protocols established by various medical authorities and health organizations in the US, which aim to improve the management of patients experiencing acute coronary events. 


Moreover, ongoing advancements in diagnostics and treatment technologies are expected to enhance the overall handling of these conditions, offering promising avenues for better management and patient care in the US Acute Coronary Syndrome Market. Understanding the nuances of each Type not only helps in effective treatment planning but also drives the continuous evolution of healthcare policies aimed at mitigating the impact of coronary diseases in the population. Overall, positioning strategies focused on these specific Types will likely shape the competitive landscape and fuel innovation in the industry, aligning well with current trends in healthcare. This comprehensive approach aids in optimizing resource allocation, aligning with evolving patient needs while contributing to the overall enhancement of cardiovascular health management in the United States.


US Acute Coronary Syndrome Market segment

Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Acute Coronary Syndrome Market Diagnosis Insights


The Diagnosis segment of the US Acute Coronary Syndrome Market plays a crucial role in identifying and managing this critical condition. Blood tests are essential for detecting biomarkers associated with heart injury, facilitating timely intervention and management of Acute Coronary Syndrome cases. Imaging techniques, including echocardiography and coronary angiography, provide valuable visualization for assessing heart function and identifying blockages, thus aiding in precise treatment planning. Stress tests are also significant as they evaluate the heart's performance under physical exertion, helping clinicians understand the severity of the condition and decision-making for further intervention or lifestyle changes.


This segment is supported by advancements in technology that have improved accuracy and efficiency in diagnosing heart diseases, which aligns well with the growing prevalence of cardiovascular diseases in the US. The increasing demand for accurate and rapid diagnostic tools in hospitals and outpatient settings drives the growth of this segment, as early diagnosis is vital for successful patient outcomes in Acute Coronary Syndrome management. Overall, the ongoing innovations and increasing awareness about heart health further enhance the importance of the Diagnosis segment within the broader US Acute Coronary Syndrome Market landscape.


US Acute Coronary Syndrome Market Key Players and Competitive Insights


The US Acute Coronary Syndrome Market is characterized by a highly competitive landscape, driven by the increasing prevalence of coronary artery diseases and advancements in therapeutic options. Key players in this market are actively involved in research and development to innovate treatment methodologies and enhance patient outcomes. Factors such as the growing aging population, lifestyle-related risk factors, and the demand for novel drugs and medical devices create a dynamic environment that encourages competition among leading pharmaceutical companies. As firms strive to capture market share, they are continuously focusing on strategic collaborations, mergers and acquisitions, and expanding their product portfolios, all while navigating regulatory challenges and evolving healthcare policies.


Merck and Co has established a notable presence in the US Acute Coronary Syndrome Market through its strong portfolio of cardiovascular products and a commitment to research-driven innovation. The company benefits from an extensive pipeline of medications designed to address various aspects of acute coronary syndromes, which positions it favorably among healthcare providers and patients. Merck’s strengths lie in its robust clinical trial capabilities, proven expertise in leveraging advanced technology for drug development, and a strategic focus on forming partnerships within the healthcare ecosystem. This collaborative approach enables Merck to enhance its product offerings and develop comprehensive management plans that can effectively cater to the diverse needs of patients suffering from acute coronary syndromes.


Bristol Myers Squibb plays a significant role in the US Acute Coronary Syndrome Market, leveraging a strong portfolio of cardiovascular therapeutics, including key products designed to manage heart disease and prevent complications. The company's presence in the market is supported by a robust pipeline of investigational therapies and a commitment to addressing unmet medical needs. Bristol Myers Squibb's strengths include its strong brand reputation, extensive clinical research capabilities, and a focus on innovation that targets various mechanisms involved in acute coronary syndromes. Additionally, Bristol Myers Squibb has pursued strategic mergers and acquisitions to enhance its capabilities and expand its product offerings, allowing it to strengthen its competitive positioning in the cardiovascular landscape. By consistently advancing its research efforts and optimizing its product development strategy, the company aims to respond effectively to the challenges faced in managing acute coronary syndromes in the US market.


Key Companies in the US Acute Coronary Syndrome Market Include



  • Merck and Co

  • Bristol Myers Squibb

  • Novartis

  • AstraZeneca

  • Roche Holding

  • Medtronic

  • Abbott Laboratories

  • Gilead Sciences

  • UnitedHealth Group

  • Thermo Fisher Scientific

  • Pfizer

  • Cardinal Health

  • Amgen

  • Sanofi

  • Johnson and Johnson


US Acute Coronary Syndrome Market Industry Developments


The US Acute Coronary Syndrome Market has seen several significant developments recently. Companies like Merck and Co, Bristol Myers Squibb, and Novartis continue to innovate with new therapies, driving growth in the market. Notably, AstraZeneca reported successful outcomes in clinical trials for a new drug aimed at reducing mortality in patients with Acute Coronary Syndrome in March 2023, reflecting ongoing advancements in treatment options. Additionally, Roche Holding announced a strategic partnership in April 2023 with Abbott Laboratories to enhance diagnostic capabilities for detecting Acute Coronary Syndrome, which may lead to improved patient outcomes. 


In terms of merger and acquisition activity, Bristol Myers Squibb acquired MyoKardia in November 2020, strengthening its cardiovascular portfolio. The market valuation for companies like Pfizer and Johnson and Johnson has increased, fueled by rising demand for effective treatments and a growing population at risk. The US represents one of the largest markets for Acute Coronary Syndrome, with increased healthcare investment and a focus on improving patient care also influencing growth trends. The regulatory environment continues to evolve in favor of rapid drug approvals, further supporting market expansion as public health initiatives focus on preventing cardiovascular diseases.


US Acute Coronary Syndrome Market Segmentation Insights


Acute Coronary Syndrome Market Type Outlook



  • Unstable Angina

  • Nstemi


Acute Coronary Syndrome Market Diagnosis Outlook



  • Blood Tests

  • Imaging

  • Stress Test

Report Attribute/Metric Source: Details
MARKET SIZE 2018 1.47(USD Billion)
MARKET SIZE 2024 1.65(USD Billion)
MARKET SIZE 2035 4.0(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR) 8.383% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
MARKET FORECAST PERIOD 2025 - 2035
HISTORICAL DATA 2019 - 2024
MARKET FORECAST UNITS USD Billion
KEY COMPANIES PROFILED Merck and Co, Bristol Myers Squibb, Novartis, AstraZeneca, Roche Holding, Medtronic, Abbott Laboratories, Gilead Sciences, UnitedHealth Group, Thermo Fisher Scientific, Pfizer, Cardinal Health, Amgen, Sanofi, Johnson and Johnson
SEGMENTS COVERED Type, Diagnosis
KEY MARKET OPPORTUNITIES Innovative diagnostic tools development, Advanced treatment modalities introduction, Telehealth integration for management, Patient education and awareness programs, Personalized medicine advancements in care
KEY MARKET DYNAMICS Rising prevalence of heart diseases, Technological advancements in treatment, Increasing healthcare expenditure, Growing geriatric population, Enhanced awareness and education
COUNTRIES COVERED US


Frequently Asked Questions (FAQ) :

The US Acute Coronary Syndrome Market is expected to be valued at 1.65 billion USD in 2024.

By 2035, the market is projected to reach a value of 4.0 billion USD.

The expected CAGR for the US Acute Coronary Syndrome Market during the forecast period is 8.383%.

Key players in the market include Merck and Co, Bristol Myers Squibb, and Novartis, among others.

The market size for Unstable Angina is valued at 0.65 billion USD in 2024.

The Nstemi segment is projected to be valued at 2.5 billion USD by 2035.

The Unstable Angina market is expected to reach 1.5 billion USD by 2035.

The growth opportunities arise from advancements in treatment modalities and increasing prevalence rates.

The market faces challenges including high treatment costs and stringent regulatory standards.

Key applications driving growth include interventions for Unstable Angina and Nstemi management.

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