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US Allergy immunotherapy Market

ID: MRFR/Pharma/15188-HCR
100 Pages
Garvit Vyas
October 2025

US Allergy Immunotherapy Market Research Report By Type (Subcutaneous Immunotherapy, Sublingual Immunotherapy, Oral Immunotherapy), By Product (Allergen Extracts, Conventional Immunotherapy, Biologics), By Indication (Allergic Rhinitis, Allergic Asthma, Atopic Dermatitis, Food Allergies) and By Patient Type (Pediatric, Adult, Geriatric) - Forecast to 2035

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US Allergy immunotherapy Market Summary

As per MRFR analysis, the US allergy immunotherapy market size was estimated at 594.3 USD Million in 2024. The US allergy immunotherapy market is projected to grow from 650.76 USD Million in 2025 to 1612.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 9.5% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US allergy immunotherapy market is experiencing robust growth driven by rising allergy incidence and technological advancements.

  • The market is witnessing a notable increase in allergy incidence, reflecting a growing patient population.
  • Technological advancements are enhancing the efficacy and safety of immunotherapy treatments.
  • Personalized treatment approaches are gaining traction, catering to individual patient needs and improving outcomes.
  • Key market drivers include increasing awareness of allergies and regulatory support for immunotherapy, which are likely to propel market growth.

Market Size & Forecast

2024 Market Size 594.3 (USD Million)
2035 Market Size 1612.0 (USD Million)

Major Players

Allergan (IE), Merck & Co (US), Aimmune Therapeutics (US), Stallergenes Greer (FR), DBV Technologies (FR), Boehringer Ingelheim (DE), Novartis (CH), Sanofi (FR), Bayer (DE)

US Allergy immunotherapy Market Trends

The allergy immunotherapy market is experiencing growth, driven by an increasing prevalence of allergic conditions among the population. This rise in allergies, particularly in children and young adults, has led to a heightened demand for effective treatment options. Immunotherapy, which aims to desensitize patients to allergens, is gaining traction as a long-term solution. The market is characterized by a variety of treatment modalities, including subcutaneous and sublingual immunotherapy, each offering unique benefits. Furthermore, advancements in technology and research are contributing to the development of more targeted therapies, enhancing patient outcomes and satisfaction. In addition to the growing demand for allergy immunotherapy, there is a noticeable shift towards personalized medicine. Patients are increasingly seeking tailored treatment plans that consider their specific allergy profiles. This trend is supported by ongoing research into genetic and environmental factors influencing allergic responses. As healthcare providers become more aware of the importance of individualized care, the allergy immunotherapy market is likely to evolve, incorporating innovative approaches to meet patient needs. Overall, the landscape appears promising, with potential for further expansion as awareness and accessibility improve.

Rising Allergy Incidence

The incidence of allergies is on the rise, particularly among children and young adults. This trend is prompting a greater focus on allergy immunotherapy as a viable treatment. As more individuals seek relief from allergic symptoms, the market is likely to expand to accommodate this growing demand.

Technological Advancements

Innovations in treatment delivery methods and diagnostic tools are transforming the allergy immunotherapy market. Enhanced technologies are enabling more precise targeting of allergens, improving treatment efficacy and patient compliance. This evolution suggests a future where therapies are more effective and accessible.

Personalized Treatment Approaches

There is a discernible shift towards personalized medicine within the allergy immunotherapy market. Healthcare providers are increasingly recognizing the need for tailored treatment plans that address individual patient profiles. This trend indicates a move towards more effective and patient-centered care.

US Allergy immunotherapy Market Drivers

Rising Healthcare Expenditure

The increase in healthcare expenditure in the US is a significant driver for the allergy immunotherapy market. With healthcare spending projected to reach approximately $6 trillion by 2027, there is a growing investment in allergy treatments, including immunotherapy. This financial commitment from both public and private sectors facilitates the development and distribution of advanced immunotherapy products. Patients are more likely to seek out these treatments as they become more affordable and accessible. Consequently, the allergy immunotherapy market stands to benefit from this upward trend in healthcare spending, which is likely to enhance patient access to effective allergy management solutions.

Increasing Awareness of Allergies

The growing awareness of allergies among the population is a crucial driver for the allergy immunotherapy market. As more individuals recognize the symptoms and implications of allergies, there is a corresponding increase in demand for effective treatment options. Educational campaigns and healthcare initiatives have contributed to this awareness, leading to a rise in consultations with allergists. In the US, it is estimated that around 30% of adults and 40% of children suffer from allergic conditions, which underscores the potential market size. This heightened awareness is likely to propel the growth of the allergy immunotherapy market as patients seek long-term solutions to manage their allergies.

Regulatory Support for Immunotherapy

Regulatory bodies in the US have shown increasing support for allergy immunotherapy, which serves as a significant driver for the market. The approval of new immunotherapy products and treatment protocols by the FDA has encouraged manufacturers to invest in research and development. This regulatory backing not only enhances the credibility of immunotherapy but also fosters innovation within the allergy immunotherapy market. For instance, the introduction of sublingual immunotherapy has expanded treatment options, making it more accessible to patients. As regulations continue to evolve favorably, the allergy immunotherapy market is expected to experience robust growth.

Advancements in Research and Development

Ongoing advancements in research and development are propelling the allergy immunotherapy market forward. Innovations in treatment methodologies, such as the development of new allergen extracts and delivery systems, are enhancing the efficacy and safety of immunotherapy. Research institutions and pharmaceutical companies are increasingly collaborating to explore novel approaches to allergy treatment, which may lead to breakthroughs in the field. The allergy immunotherapy market is likely to see a surge in new products and therapies as a result of these R&D efforts, potentially improving patient outcomes and expanding treatment options.

Growing Demand for Alternative Therapies

The rising demand for alternative therapies is influencing the allergy immunotherapy market significantly. Patients are increasingly seeking holistic and long-term solutions to manage their allergies, moving away from traditional symptomatic treatments. This shift in patient preference is driving interest in immunotherapy, which offers a more sustainable approach to allergy management. As awareness of the benefits of immunotherapy grows, more individuals are likely to consider it as a viable option. This trend suggests a promising future for the allergy immunotherapy market, as it aligns with the evolving expectations of patients seeking comprehensive care.

Market Segment Insights

By Type: Subcutaneous Immunotherapy (Largest) vs. Sublingual Immunotherapy (Fastest-Growing)

The US allergy immunotherapy market showcases a diverse landscape with Subcutaneous Immunotherapy leading in market share. This method is predominantly favored by healthcare providers due to its established efficacy in treating various allergies through controlled exposure. Sublingual Immunotherapy, while holding a smaller share, demonstrates a growing preference among patients seeking non-invasive alternatives, contributing to a shift in market dynamics. Growth trends are significantly influenced by increasing awareness of allergy management and rising incidences of allergic conditions. The demand for convenient and at-home treatment options fuels the adoption of Sublingual Immunotherapy as a viable alternative to traditional methods. Additionally, continuous advancements in formulations and delivery mechanisms are enhancing patient experiences, further driving the market expansion.

Subcutaneous Immunotherapy (Dominant) vs. Sublingual Immunotherapy (Emerging)

Subcutaneous Immunotherapy remains the dominant segment in the US allergy immunotherapy market, revered for its comprehensive treatment capabilities and extensive clinical backing. Patients receive allergen injections based on a tailored schedule, leading to significant long-term relief from allergic symptoms. Conversely, Sublingual Immunotherapy is emerging as a popular choice due to its convenience and ease of administration, allowing patients to self-administer at home. This segment is characterized by rapid growth, appealing particularly to those who prefer non-invasive methods. Its rising popularity underscores a broader shift towards patient-centric therapy options, as healthcare providers recognize the importance of flexibility and accessibility in allergy treatments.

By Product: Allergen Extracts (Largest) vs. Biologics (Fastest-Growing)

In the US allergy immunotherapy market, allergen extracts maintain the largest market share, leveraging their time-tested applicability and strong acceptance by both patients and healthcare providers. This category benefits from established protocols and a wide range of applications, ranging from environmental allergens to food allergies, ensuring a consistent demand across demographic segments. Conversely, biologics represent the fastest-growing segment in the US allergy immunotherapy market. This growth is driven by advancements in research leading to novel biologic treatments that provide targeted and efficient allergy relief, along with increasing consumer awareness and preference for innovative solutions that promise better efficiency and fewer side effects than traditional methods.

Allergen Extracts (Dominant) vs. Biologics (Emerging)

Allergen extracts are the dominant segment in the US allergy immunotherapy market, characterized by their foundational role in treating various allergies through targeted treatment. These extracts undergo rigorous testing and standardization, ensuring efficacy and safety in a wide range of clinical applications. In contrast, biologics, as an emerging segment, are gaining significant traction due to their ability to offer customized and potent therapeutic options. These biologics often combine monoclonal antibodies and advanced therapeutic techniques, achieving impressive outcomes in allergy management and showcasing a rapid adoption rate due to their innovative nature. The dual presence of allergen extracts and biologics creates a rich tapestry of treatment options that cater to diverse patient needs.

By Indication: Allergic Rhinitis (Largest) vs. Food Allergies (Fastest-Growing)

In the US allergy immunotherapy market, Allergic Rhinitis represents the largest segment, capturing a significant share due to its higher prevalence among the population. Allergic Asthma and Atopic Dermatitis follow, but with a smaller market presence. Food Allergies, while not the largest, are rapidly gaining traction, especially among children, indicating a shift in consumer focus and awareness of food-related allergens. This dynamic distribution highlights the diverse needs of patients seeking effective therapies for their specific allergies. The growth trends within this segment reveal that Allergic Rhinitis remains steady, bolstered by ongoing research and advancements in treatment options. However, the rise of Food Allergies as the fastest-growing segment can be attributed to increasing incidences of food allergies and the growing demand for innovative therapies. Consumer education and awareness campaigns are also significant contributors, enhancing the market's landscape and fostering growth across all segments.

Allergic Rhinitis (Dominant) vs. Food Allergies (Emerging)

Allergic Rhinitis is the dominant force within the US allergy immunotherapy market, thanks to its high incidence rate and the availability of varied treatment options, including sublingual immunotherapy. Patients suffering from this condition often seek relief due to the significant impact on their quality of life. In contrast, Food Allergies are emerging with increasing significance, particularly among younger demographics. The rise in diagnosis rates and heightened awareness regarding food allergens are pushing this segment forward. With fewer established treatments compared to Allergic Rhinitis, there is immense potential for innovation and breakthroughs, making it a pivotal area of growth for future market endeavors.

By Patient Type: Pediatric (Largest) vs. Geriatric (Fastest-Growing)

In the US allergy immunotherapy market, the Patient Type segment is primarily divided into Pediatric, Adult, and Geriatric categories. Pediatric patients represent the largest share of this market segment, driven by the increasing prevalence of allergic conditions among children. Adults also constitute a significant portion, yet Geriatric patients are emerging with noteworthy growth rates as they increasingly seek treatment options for allergy-related issues, reflecting demographic trends and rising awareness of allergy management. Growth trends within the Patient Type segment indicate a shift towards more tailored immune therapies, with Pediatric patients benefiting from advancements in treatment methodologies. The Geriatric segment is observing rapid expansion, attributed to the aging population and a greater focus on health and longevity. Additionally, rising healthcare access and educational initiatives are propelling demand, especially for immunotherapy solutions that cater specifically to the unique needs of older adults.

Pediatric (Dominant) vs. Geriatric (Emerging)

The Pediatric segment of the US allergy immunotherapy market is characterized by a robust framework of treatment options designed specifically for children that emphasize safety and efficacy. Many modern immunotherapy solutions for Pediatric patients are administered in a controlled environment, ensuring minimal adverse effects. In contrast, the Geriatric segment is gaining traction, with an increasing number of older adults recognizing the importance of managing allergies that can significantly impact their quality of life. This segment is now witnessing innovations like oral immunotherapy, adjusting treatment protocols to accommodate age-related health considerations. As a result, while Pediatric remains the dominant segment in the market, Geriatric has emerged as a vital area for growth, driving new research and therapeutic developments.

Get more detailed insights about US Allergy immunotherapy Market

Key Players and Competitive Insights

The allergy immunotherapy market is currently characterized by a dynamic competitive landscape, driven by increasing prevalence of allergic conditions and a growing demand for effective treatment options. Key players such as Merck & Co (US), Aimmune Therapeutics (US), and Sanofi (FR) are strategically positioned to leverage innovation and partnerships to enhance their market presence. Merck & Co (US) focuses on expanding its portfolio through research and development, while Aimmune Therapeutics (US) emphasizes its commitment to developing novel therapies for food allergies. Sanofi (FR) is actively pursuing collaborations to enhance its immunotherapy offerings, indicating a trend towards cooperative strategies that shape the competitive environment.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and responsiveness to market demands. The market structure appears moderately fragmented, with several players vying for market share. However, the collective influence of major companies like Merck & Co (US) and Sanofi (FR) suggests a trend towards consolidation, as these firms seek to strengthen their competitive positions through strategic initiatives.

In October 2025, Aimmune Therapeutics (US) announced a partnership with a leading biotechnology firm to accelerate the development of its peanut allergy treatment. This collaboration is expected to enhance Aimmune's research capabilities and expedite the clinical trial process, potentially positioning the company as a leader in the food allergy segment. The strategic importance of this partnership lies in its potential to bring innovative solutions to market more rapidly, thereby addressing a significant unmet need in allergy treatment.

In September 2025, Merck & Co (US) launched a new digital platform aimed at improving patient engagement and adherence to immunotherapy regimens. This initiative reflects a broader trend towards digital transformation within the healthcare sector, as companies seek to leverage technology to enhance patient outcomes. By focusing on patient-centric solutions, Merck & Co (US) is likely to strengthen its market position and foster long-term loyalty among patients and healthcare providers.

In August 2025, Sanofi (FR) expanded its immunotherapy portfolio by acquiring a small biotech firm specializing in novel allergen immunotherapy technologies. This acquisition not only diversifies Sanofi's offerings but also enhances its research capabilities in the allergy space. The strategic significance of this move lies in Sanofi's ability to integrate innovative technologies into its existing product lines, thereby reinforcing its competitive edge in a rapidly evolving market.

As of November 2025, current trends in the allergy immunotherapy market include a strong emphasis on digitalization, sustainability, and the integration of artificial intelligence (AI) in treatment development. Strategic alliances are increasingly shaping the landscape, as companies recognize the value of collaboration in driving innovation. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition to a focus on technological advancements, innovative therapies, and reliable supply chains. This shift underscores the importance of agility and responsiveness in meeting the diverse needs of patients and healthcare providers.

Key Companies in the US Allergy immunotherapy Market market include

Industry Developments

The US Allergy Immunotherapy Market has been witnessing significant developments recently. Notably, in August 2023, Stallergenes Greer announced the expansion of their product line with a new sublingual immunotherapy treatment aimed at grass pollen allergies, which is expected to enhance patient access to allergen management. In October 2023, Aimmune Therapeutics received FDA approval for their peanut protein immunotherapy, further solidifying their position in the market. The ongoing collaboration between Merck and Regeneron Pharmaceuticals continues to advance research and development in this field, potentially leading to innovative treatment solutions.

Additionally, in June 2023, Allergy Therapeutics completed a merger with a biotechnology firm focused on developing novel therapies, which is anticipated to enhance their market presence. Market valuations for companies such as Novartis and Merck have shown upward trends, driven by increased demand for effective allergy treatments and advancements in immunotherapy techniques. The overall market for allergy immunotherapy is expected to experience substantial growth in the coming years, especially with increasing awareness about allergic conditions and the effectiveness of immunotherapy as a long-term management solution.

Notable happenings include the FDA's focus on expediting approvals for novel therapies, which has fueled competitive dynamics among key players.

Future Outlook

US Allergy immunotherapy Market Future Outlook

The allergy immunotherapy market is projected to grow at a 9.5% CAGR from 2024 to 2035, driven by increasing allergy prevalence, technological advancements, and rising consumer awareness.

New opportunities lie in:

  • Development of personalized immunotherapy solutions for specific allergens.
  • Expansion of telehealth services for remote allergy consultations.
  • Investment in AI-driven diagnostics for improved patient targeting.

By 2035, the market is expected to achieve substantial growth, driven by innovation and increased accessibility.

Market Segmentation

US Allergy immunotherapy Market Type Outlook

  • Subcutaneous Immunotherapy
  • Sublingual Immunotherapy
  • Oral Immunotherapy

US Allergy immunotherapy Market Product Outlook

  • Allergen Extracts
  • Conventional Immunotherapy
  • Biologics

US Allergy immunotherapy Market Indication Outlook

  • Allergic Rhinitis
  • Allergic Asthma
  • Atopic Dermatitis
  • Food Allergies

US Allergy immunotherapy Market Patient Type Outlook

  • Pediatric
  • Adult
  • Geriatric

Report Scope

MARKET SIZE 2024594.3(USD Million)
MARKET SIZE 2025650.76(USD Million)
MARKET SIZE 20351612.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)9.5% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies ProfiledAllergan (IE), Merck & Co (US), Aimmune Therapeutics (US), Stallergenes Greer (FR), DBV Technologies (FR), Boehringer Ingelheim (DE), Novartis (CH), Sanofi (FR), Bayer (DE)
Segments CoveredType, Product, Indication, Patient Type
Key Market OpportunitiesAdvancements in personalized medicine enhance efficacy and patient adherence in the allergy immunotherapy market.
Key Market DynamicsRising consumer awareness drives demand for innovative allergy immunotherapy solutions amid evolving regulatory frameworks.
Countries CoveredUS

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FAQs

What is the expected market size of the US Allergy Immunotherapy Market in 2024?

The US Allergy Immunotherapy Market is expected to be valued at 1.2 billion USD in 2024.

What is the projected market value of the US Allergy Immunotherapy Market by 2035?

By 2035, the market is projected to reach a value of 2.62 billion USD.

What is the expected CAGR for the US Allergy Immunotherapy Market from 2025 to 2035?

The expected CAGR for the market from 2025 to 2035 is 7.383%.

Which type of immunotherapy segment is expected to have the highest value in 2035?

Subcutaneous Immunotherapy is expected to have the highest value, projected at 1.08 billion USD in 2035.

What is the market size of Sublingual Immunotherapy in 2024?

Sublingual Immunotherapy is valued at 0.36 billion USD in 2024.

Who are the major players in the US Allergy Immunotherapy Market?

Key players include Stallergenes Greer, Novartis, Merck, and Aimmune Therapeutics.

What is the total market value for Oral Immunotherapy in 2035?

The market value for Oral Immunotherapy is projected to reach 0.76 billion USD by 2035.

How does the market value for Subcutaneous Immunotherapy compare to Sublingual and Oral Immunotherapy in 2035?

In 2035, Subcutaneous Immunotherapy leads with 1.08 billion USD, followed by Sublingual at 0.78 billion USD and Oral at 0.76 billion USD.

What is an emerging trend in the US Allergy Immunotherapy Market?

An emerging trend is the growing preference for Sublingual and Oral Immunotherapy due to convenience and ease of administration.

What challenges does the US Allergy Immunotherapy Market face?

Challenges include regulatory hurdles and the need for extensive clinical trials to prove efficacy and safety.

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