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US Endometrial Cancer Market

ID: MRFR/MED/15168-HCR
100 Pages
Garvit Vyas
October 2025

US Endometrial Cancer Market Research Report By Type of Treatment (Surgery, Radiation Therapy, Chemotherapy, Hormonal Therapy, Targeted Therapy), By Diagnosis Method (Biopsy, Imaging Tests, Pelvic Exam, Endometrial Sampling), By End User (Hospitals, Cancer Research Centers, Diagnostic Laboratories, Ambulatory Surgical Centers) and By Stage of Cancer (Early Stage, Locally Advanced Stage, Metastatic Stage) - Forecast to 2035

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US Endometrial Cancer Market Infographic
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US Endometrial Cancer Market Summary

As per analysis, the US endometrial cancer market is projected to grow from USD 3.84 Billion in 2024 to USD 7.46 Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 6.21% during the forecast period (2025 - 2035).

Key Market Trends & Highlights

The US endometrial cancer market is experiencing a shift towards personalized treatment and technological advancements.

  • Personalized treatment approaches are becoming increasingly prevalent in the management of endometrial cancer.
  • Surgical interventions remain the largest segment, while chemotherapy is emerging as the fastest-growing treatment modality.
  • Stage I endometrial cancer represents the largest patient population, whereas Stage III is witnessing the most rapid growth.
  • The increasing incidence of endometrial cancer and advancements in diagnostic technologies are key drivers of market expansion.

Market Size & Forecast

2024 Market Size 3.84 (USD Billion)
2035 Market Size 7.46 (USD Billion)
CAGR (2025 - 2035) 6.21%

Major Players

Merck & Co (US), Bristol-Myers Squibb (US), Pfizer Inc (US), AstraZeneca (GB), GSK (GB), Eli Lilly and Company (US), Novartis (CH), Bayer AG (DE), Amgen Inc (US)

US Endometrial Cancer Market Trends

The US endometrial cancer market is currently experiencing notable shifts driven by advancements in treatment modalities and increasing awareness surrounding women's health issues. The rise in the incidence of endometrial cancer has prompted healthcare providers to focus on early detection and innovative therapeutic approaches. This evolving landscape is characterized by a growing emphasis on personalized medicine, which tailors treatment plans to individual patient profiles, thereby enhancing efficacy and minimizing adverse effects. Furthermore, the integration of cutting-edge technologies, such as telemedicine and digital health platforms, is transforming patient engagement and access to care, making it easier for women to seek timely interventions. In addition to these advancements, the US endometrial cancer market is witnessing a surge in research initiatives aimed at understanding the underlying genetic and environmental factors contributing to the disease. This research is likely to pave the way for novel therapeutic targets and preventive strategies. Moreover, the collaboration between academic institutions and pharmaceutical companies appears to be fostering innovation in drug development, potentially leading to the introduction of new treatment options in the near future. As the market continues to evolve, stakeholders must remain vigilant in addressing the challenges posed by disparities in healthcare access and the need for comprehensive support systems for patients and their families.

Personalized Treatment Approaches

The US endometrial cancer market is increasingly leaning towards personalized treatment strategies. This trend emphasizes tailoring therapies based on individual patient characteristics, including genetic profiles and tumor biology. Such an approach may enhance treatment outcomes and reduce side effects, thereby improving the overall patient experience.

Technological Integration in Care Delivery

The integration of advanced technologies into the US endometrial cancer market is transforming how care is delivered. Telemedicine and digital health tools are facilitating remote consultations and monitoring, which could lead to improved patient engagement and adherence to treatment plans. This shift may also enhance access to care for underserved populations.

Research and Development Initiatives

Ongoing research initiatives in the US endometrial cancer market are focused on uncovering the disease's genetic and environmental determinants. This research is likely to inform the development of novel therapies and preventive measures, potentially reshaping treatment paradigms and improving patient outcomes.

Market Segment Insights

By Treatment Type: Surgery (Largest) vs. Chemotherapy (Fastest-Growing)

In the US endometrial cancer market, the treatment landscape is dominated by surgery, which holds the largest market share among available treatment types. Surgery is often the first line of treatment for endometrial cancer, contributing significantly to patient outcomes and overall survival rates. Following surgery, radiation therapy, chemotherapy, and hormonal therapy make up the remaining segments, with chemotherapy showing robust utilization due to its effectiveness in systemic control of cancer, especially in advanced stages.

Surgery: Dominant vs. Chemotherapy: Emerging

Surgery remains the dominant treatment modality in managing endometrial cancer, as it typically involves the complete surgical removal of the uterus and surrounding tissues, effectively addressing localized tumors. Its established position is supported by clinical guidelines and the critical role it plays in early-stage detection and treatment. On the other hand, chemotherapy is emerging as a vital component in this market, particularly for patients diagnosed with advanced or recurrent cancers. This treatment approach is gaining traction as an effective strategy to manage systemic disease and enhance survival rates among patients, driven by newer drug formulations and combination therapies that boost efficacy and tolerability.

By Stage of Cancer: Stage I (Largest) vs. Stage III (Fastest-Growing)

In the US endometrial cancer market, Stage I represents the largest segment due to early diagnosis and a relatively high survival rate, accounting for a significant portion of total cases. This stage features a market characterized by less aggressive treatment options, which appeals to many patients seeking effective yet less invasive solutions. Comparatively, Stage III accounts for a growing share of the market as advances in screening techniques enable better detection rates, expanding treatment approaches offered to patients.

Stage I (Dominant) vs. Stage III (Emerging)

Stage I of endometrial cancer is recognized as the dominant segment, primarily due to its favorable prognosis and simpler treatment regimens, which are vital for patient compliance. Typically identified early, patients often experience a variety of treatment options like minimally invasive surgeries and hormone therapy. In contrast, Stage III, while still a smaller segment, is marked as emerging due to an increase in awareness and improved diagnostic capabilities. The treatments in this stage tend to be more aggressive and multifaceted, often involving a combination of chemotherapy and radiation, targeting broader patient needs despite higher complexity.

By Histological Type: Endometrioid Carcinoma (Largest) vs. Serous Carcinoma (Fastest-Growing)

In the US endometrial cancer market, the histological types present a varied market share distribution, with Endometrioid Carcinoma representing the largest segment. It historically accounts for a significant portion of endometrial cancer cases due to its prevalence among patients. In contrast, Serous Carcinoma, while smaller in share, demonstrates rapid growth as research advances uncover newer treatment options and awareness of the disease increases. The diversity in histological presentation highlights the complexities of managing endometrial cancer. Growth trends in this segment are influenced by increasing awareness of different histological types and significant advancements in targeted therapies. Serous Carcinoma is positioned for accelerated growth driven by its recognition as a more aggressive form of endometrial cancer, necessitating early intervention. Additionally, medical professionals are becoming more versed in the various histological types, leading to improved diagnostic methods and therapeutic approaches that cater to each specific cancer type. Such trends are crucial as they align with the growing demand for personalized medicine in oncology.

Endometrioid Carcinoma (Dominant) vs. Serous Carcinoma (Emerging)

Endometrioid Carcinoma remains the dominant histological type in the US endometrial cancer market, characterized by its prevalence among patients, particularly in early-stage diagnoses. It tends to be associated with better prognoses and is often responsive to treatment, making it a primary focus for healthcare providers. Conversely, Serous Carcinoma, recognized as an emerging segment, is gaining focus due to its aggressive nature and the increasing severity of cases observed in recent years. Its rapid growth is propelled by advancements in research and treatment, shifting clinical focus toward improving patient outcomes. As awareness of Serous Carcinoma improves, so do the resources dedicated to its diagnosis and management. This dynamic indicates a distinct shift in the landscape of endometrial cancer care.

By Patient Demographics: Age Group (Largest) vs. Ethnicity (Fastest-Growing)

In the US endometrial cancer market, demographics play a significant role in patient distribution and treatment plans. The largest age group affected by endometrial cancer comprises women aged 50-64 years, representing a substantial portion of diagnoses. Meanwhile, the impact of ethnicity on the disease is also notable, as rates differ across various racial and ethnic groups, indicating specific susceptibilities and healthcare access disparities that affect overall outcomes.

Age Group: 50-64 (Dominant) vs. Ethnicity: Hispanic (Emerging)

Women aged 50-64 hold a dominant position in the US endometrial cancer market, highlighting the necessity for targeted screening and treatment protocols for this demographic, which faces a distinct risk profile. Conversely, the Hispanic population emerges as a key demographic, exhibiting increasing incidence rates, potentially driven by factors such as genetic predispositions and social determinants of health. Understanding these characteristics allows for tailored healthcare strategies to effectively address the needs of diverse patient groups.

By Diagnosis Method: Biopsy (Largest) vs. Imaging Tests (Fastest-Growing)

In the US endometrial cancer market, the diagnosis method segment is primarily dominated by biopsy techniques, which hold the largest market share. This method is widely recognized for its accuracy in obtaining tissue samples, leading to definitive diagnosis. Imaging tests, while a smaller share of the market, are increasingly being employed for their non-invasive nature and ability to visualize tumors, thus paving the way for earlier detection and treatment options.

Diagnosis Methods: Biopsy (Dominant) vs. Imaging Tests (Emerging)

Biopsy remains the dominant method for diagnosing endometrial cancer in the US, known for its precision in confirming cancer presence through histological examination. It continues to be the preferred choice among healthcare providers due to its established efficacy and reliability. Conversely, imaging tests, while emerging, are rapidly gaining traction as they offer non-invasive alternatives that enhance early detection capabilities. Techniques such as ultrasound, MRI, and CT scans are becoming integral, particularly in initial assessments. As technology advances, imaging tests are poised to play a vital role in patient management, reflecting a shift towards a more comprehensive approach in endometrial cancer diagnostics.

Get more detailed insights about US Endometrial Cancer Market

Key Players and Competitive Insights

The endometrial cancer market is characterized by a dynamic competitive landscape, driven by increasing incidence rates and advancements in treatment modalities. Key players such as Merck & Co (US), Bristol-Myers Squibb (US), and Pfizer Inc (US) are at the forefront, focusing on innovative therapies and strategic partnerships to enhance their market presence. Merck & Co (US) has positioned itself as a leader in immunotherapy, while Bristol-Myers Squibb (US) emphasizes combination therapies to improve patient outcomes. Pfizer Inc (US) is leveraging its extensive research capabilities to develop targeted therapies, thereby shaping a competitive environment that prioritizes innovation and patient-centric solutions.

In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and responsiveness to market demands. The competitive structure of the market appears moderately fragmented, with several players vying for market share. However, the collective influence of major companies is significant, as they drive advancements in treatment options and establish robust distribution networks.

In November 2025, Merck & Co (US) announced a collaboration with a leading biotechnology firm to develop a novel combination therapy for endometrial cancer. This strategic move is likely to enhance Merck's portfolio and position it favorably against competitors, as combination therapies have shown promise in improving treatment efficacy. The partnership underscores the importance of innovation in addressing unmet medical needs in this therapeutic area.

In October 2025, Bristol-Myers Squibb (US) launched a new clinical trial aimed at evaluating the effectiveness of its latest immunotherapy in patients with advanced endometrial cancer. This initiative reflects the company's commitment to advancing research and development, potentially leading to new treatment options that could significantly impact patient care. The trial's outcomes may provide critical insights into the role of immunotherapy in this specific cancer type.

In September 2025, Pfizer Inc (US) expanded its oncology pipeline by acquiring a promising biotech firm specializing in endometrial cancer therapies. This acquisition is indicative of Pfizer's strategy to bolster its research capabilities and diversify its product offerings. By integrating innovative technologies and expertise from the acquired firm, Pfizer is likely to enhance its competitive edge in the market.

As of December 2025, current trends in the endometrial cancer market include a strong emphasis on digitalization, sustainability, and the integration of artificial intelligence in drug development. Strategic alliances are increasingly shaping the landscape, enabling companies to pool resources and expertise. Looking ahead, competitive differentiation is expected to evolve, with a shift from price-based competition to a focus on innovation, technological advancements, and supply chain reliability. This transition may redefine how companies approach market entry and product development, ultimately benefiting patients through improved treatment options.

Key Companies in the US Endometrial Cancer Market market include

Industry Developments

The US Endometrial Cancer Market has seen significant developments recently, with companies like AstraZeneca and Merck enhancing their drug portfolios. AstraZeneca is focusing on the trials for its pipeline drugs targeting endometrial cancer, indicating a strategic push toward innovative treatments. In June 2023, Celgene announced promising outcomes from their clinical trials, contributing positively to their market valuation. Additionally, Bristol Myers Squibb actively pursued collaborations to innovate therapies in this sector.

In terms of mergers and acquisitions, Eli Lilly announced the acquisition of a biotechnology firm in July 2023, aimed at bolstering its offerings in oncology, including endometrial cancer. Pfizer, also in the spotlight, had a successful merger with a small-scale firm in August 2023 to enhance its Research and Development capabilities around hormone receptor-positive endometrial cancer therapies.

The overall market for endometrial cancer treatments in the US is projected to grow, driven by advancements from companies such as Roche and AbbVie. This growth is, in part, due to increased funding for research, as outlined in the National Cancer Institute's latest reports, highlighting the urgency of addressing this challenging disease.

Future Outlook

US Endometrial Cancer Market Future Outlook

The US endometrial cancer market is projected to grow at a 6.21% CAGR from 2024 to 2035, driven by advancements in treatment options, increasing awareness, and rising incidence rates.

New opportunities lie in:

  • Development of personalized immunotherapy treatments for endometrial cancer patients.
  • Expansion of telehealth services for remote patient monitoring and consultations.
  • Investment in AI-driven diagnostic tools to enhance early detection and treatment planning.

By 2035, the endometrial cancer market is expected to achieve substantial growth, reflecting evolving treatment paradigms and increased patient engagement.

Market Segmentation

US Endometrial Cancer Market Treatment Type Outlook

  • Surgery
  • Radiation Therapy
  • Chemotherapy
  • Hormonal Therapy

US Endometrial Cancer Market Stage of Cancer Outlook

  • Stage I
  • Stage II
  • Stage III
  • Stage IV

US Endometrial Cancer Market Diagnosis Method Outlook

  • Biopsy
  • Imaging Tests
  • Endometrial Sampling

US Endometrial Cancer Market Histological Type Outlook

  • Endometrioid Carcinoma
  • Serous Carcinoma
  • Clear Cell Carcinoma
  • Mixed Cell Carcinoma

US Endometrial Cancer Market Patient Demographics Outlook

  • Age Group
  • Ethnicity
  • Socioeconomic Status

Report Scope

MARKET SIZE 20243.84(USD Billion)
MARKET SIZE 20254.08(USD Billion)
MARKET SIZE 20357.46(USD Billion)
COMPOUND ANNUAL GROWTH RATE (CAGR)6.21% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Billion
Key Companies ProfiledMerck & Co (US), Bristol-Myers Squibb (US), Pfizer Inc (US), AstraZeneca (GB), GSK (GB), Eli Lilly and Company (US), Novartis (CH), Bayer AG (DE), Amgen Inc (US)
Segments CoveredTreatment Type, Stage of Cancer, Histological Type, Patient Demographics, Diagnosis Method
Key Market OpportunitiesAdvancements in personalized medicine and targeted therapies enhance treatment options in the US endometrial cancer market.
Key Market DynamicsRising demand for personalized therapies drives innovation in the US endometrial cancer treatment landscape.
Countries CoveredUS

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FAQs

What is the expected market size of the US Endometrial Cancer Market in 2024?

The US Endometrial Cancer Market is expected to be valued at 841.75 million USD in 2024.

What is the projected market size for the US Endometrial Cancer Market by 2035?

The market is projected to reach approximately 1828.35 million USD by the year 2035.

What is the expected CAGR for the US Endometrial Cancer Market from 2025 to 2035?

The expected CAGR for the US Endometrial Cancer Market during this period is 7.306 percent.

Which treatment type is predicted to dominate the US Endometrial Cancer Market in 2024?

Surgery is predicted to dominate the market with an estimated value of 300 million USD in 2024.

What is the value of the Chemotherapy segment in the US Endometrial Cancer Market for 2024?

The Chemotherapy segment is valued at approximately 200 million USD in 2024.

Which companies are considered major players in the US Endometrial Cancer Market?

Major players include Celgene, AstraZeneca, Novartis, Merck, and Eli Lilly, among others.

What is the expected market size for the Hormonal Therapy segment by 2035?

The Hormonal Therapy segment is expected to reach about 200 million USD by 2035.

What growth opportunities exist in the US Endometrial Cancer Market?

Increasing incidence rates of endometrial cancer and advancements in treatment options present growth opportunities.

How much is the Targeted Therapy segment expected to grow by 2035?

The Targeted Therapy segment is expected to grow to approximately 328.35 million USD by 2035.

What challenges does the US Endometrial Cancer Market face currently?

Challenges include high treatment costs and varying access to advanced therapies across different regions.

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