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    Avascular Necrosis Market

    ID: MRFR/MED/4673-CR
    539 Pages
    Kinjoll Dey
    June 2018

    Avascular Necrosis Market Research Report Information By Type (Trauma Related Avascular Necrosis (AVN) and Non-Trauma Related Avascular Necrosis (AVN)0, By Treatment (Nonsteroidal Anti-Inflammatory Drugs (NSAIDS), Cholesterol Lowing Drugs, Osteoporosis Drugs, Blood Thinners, and Others), By Diagnosis (Imaging, Biopsy, CT Scan, PET and X- Ray), By End User (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2035

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    Avascular Necrosis Market Infographic
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    Avascular Necrosis Market Summary

    The Global Avascular Necrosis Market is projected to grow from 0.56 USD Billion in 2024 to 1.04 USD Billion by 2035.

    Key Market Trends & Highlights

    Avascular Necrosis Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 5.73 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 1.04 USD Billion, indicating robust growth potential.
    • in 2024, the market is valued at 0.56 USD Billion, reflecting the current demand for treatment options.
    • Growing adoption of innovative treatment modalities due to increasing prevalence of avascular necrosis is a major market driver.

    Market Size & Forecast

    2024 Market Size 0.56 (USD Billion)
    2035 Market Size 1.04 (USD Billion)
    CAGR (2025-2035) 5.72%

    Major Players

    Dr. Reddy’s Laboratories Ltd., Novartis AG, Pfizer Inc, Teva Pharmaceutical Industries Ltd, Mylan N.V, Zimmer Biomet, Merck & Co. Inc, Enzo Biochem Inc, Atnahs, Bone Therapeutics, SAVericel Corporation

    Avascular Necrosis Market Trends

    Growing accidents is driving the market growth

    Market CAGR for avascular necrosis is being driven by the rising fatal accidents. Avascular necrosis is a condition that develops after a fractured hip or dislocation, a hard impact from an automobile accident, or both. As a result of car collisions in traffic accidents, people might suffer serious injuries such as fractured bones and dislocated hips, as well as blood flow difficulties. Traumatic injuries develop when the femoral head's dislocation and fracture cut off the blood supply to the area. 

    Trauma injuries like fractures to the neck of the talus frequently occur as a result of car accidents, falls, sports injuries, natural disasters, and other physical mishaps that occur at home, at work, and while walking down the street. Avascular Necrosis is another condition commonly affecting kids and is brought on by cancer treatment. 

    Avascular Necrosis of the proximal femoral head is known as Legg-Calvé-Perthes disease (LCPD), and it frequently affects kids between the ages of 4 and 10 years old. As a result, the demand for avascular necrosis market is fueled by the rise in traffic accidents, severe injuries, and occurrence in youngsters.

    The bone marrow aspirate and concentration is a novel, practical method that detects hip avascular necrosis in its early stages. The surgeon removes a sample of the dead hipbone while operating on the bone marrow and replaces it with stem cells obtained from the bone marrow. Thus, bone marrow aspirate and concentration surgery are the most common technology for treating avascular Necrosis. Bone cell treatment, which treats avascular Necrosis (AVN) by employing the patient's cells as a therapeutic instrument, is the only long-term cure for the condition. 

    The disease's progression is stopped by bone cell treatment, improving mobility. Another regenerative medicine technique is tissue engineering, which aids in regenerating the necrotic bone tissues and the vasculature in the femoral head, a key contributor to the condition.

    One of the key factors propelling the avascular necrosis market's revenue growth is the rise in avascular necrosis prevalence caused by an increase in unhealthy behaviors like alcohol or cigarette intake or smoking in a growing population.Avascular necrosis risk is increased by several chronic conditions, including diabetes, HIV, or by some unfavorable reactions to cancer therapy and organ transplants, which helps drive the avascular necrosis market's revenue growth. 

    The market for avascular Necrosis is expanding due to the excessive use of steroids in numerous other treatments, which raises the risk of avascular Necrosis. Thus, driving the Avascular Necrosis market revenue.

    The rising prevalence of avascular necrosis, coupled with advancements in diagnostic techniques and treatment options, suggests a growing need for comprehensive management strategies in the healthcare system.

    Centers for Disease Control and Prevention (CDC)

    Avascular Necrosis Market Drivers

    Market Growth Projections

    The Global Avascular Necrosis Market Industry is poised for substantial growth, with projections indicating a market value of 0.56 USD Billion in 2024 and an anticipated increase to 1.04 USD Billion by 2035. This growth reflects a compound annual growth rate (CAGR) of 5.73% from 2025 to 2035, driven by factors such as rising incidence rates, advancements in diagnostics, and increased R&D investments. The market's expansion is indicative of the evolving landscape of AVN treatment and the ongoing commitment to improving patient outcomes.

    Rising Geriatric Population

    The global increase in the geriatric population is a significant factor influencing the Global Avascular Necrosis Market Industry. Older adults are more susceptible to conditions that lead to AVN, such as osteoporosis and other degenerative diseases. As the population aged 65 and above continues to grow, the demand for AVN treatments is expected to rise correspondingly. This demographic shift is likely to contribute to the market's expansion, with projections indicating a market value of 1.04 USD Billion by 2035, as healthcare systems adapt to the needs of an aging population.

    Advancements in Diagnostic Techniques

    Technological advancements in diagnostic imaging, such as MRI and CT scans, enhance the detection of avascular necrosis at earlier stages. These innovations facilitate timely intervention, which is crucial for improving patient outcomes. The Global Avascular Necrosis Market Industry benefits from these advancements, as they lead to increased diagnosis rates and subsequent treatment demand. As healthcare providers adopt these advanced techniques, the market is projected to grow, potentially reaching 1.04 USD Billion by 2035, driven by the need for early and accurate diagnosis.

    Increasing Incidence of Avascular Necrosis

    The rising prevalence of avascular necrosis (AVN) globally is a primary driver for the Global Avascular Necrosis Market Industry. Factors such as increased alcohol consumption, steroid use, and certain medical conditions contribute to the growing incidence of AVN. For instance, studies indicate that approximately 10,000 new cases of AVN are diagnosed annually in the United States alone. This trend suggests a potential market value of 0.56 USD Billion in 2024, reflecting the urgent need for effective treatment options and increased awareness surrounding the condition.

    Enhanced Awareness and Education Initiatives

    Increased awareness and education initiatives regarding avascular necrosis are crucial for the Global Avascular Necrosis Market Industry. Healthcare organizations and advocacy groups are actively working to inform both patients and healthcare providers about the condition, its risk factors, and treatment options. This heightened awareness is likely to lead to earlier diagnosis and treatment, ultimately driving market growth. As more individuals become informed about AVN, the demand for effective therapies is expected to rise, contributing to the market's projected growth trajectory.

    Growing Research and Development Investments

    Increased investments in research and development for AVN treatments are propelling the Global Avascular Necrosis Market Industry forward. Pharmaceutical companies and research institutions are focusing on innovative therapies, including regenerative medicine and stem cell treatments. This surge in R&D is expected to yield new treatment options, enhancing patient care. With a projected compound annual growth rate (CAGR) of 5.73% from 2025 to 2035, the market is likely to expand significantly as new therapies emerge, addressing the unmet needs of AVN patients.

    Market Segment Insights

    Avascular Necrosis Type Insights

    Based on type, the  Avascular Necrosis market segmentation includes trauma-related avascular necrosis (AVN) and non-trauma-related avascular necrosis (AVN). The non-trauma-related avascular necrosis (AVN) segment dominated the market, accounting for 66% of market revenue. The causes of these increases are increased alcohol consumption, metabolic bone disorders, and other illnesses. 

    The main disability in young people is non-traumatic avascular necrosis of the femoral head, which has a high medical cost. The prevalence of femoral head necrosis has significantly grown in recent years due to rising testosterone usage and alcohol consumption.

    Avascular Necrosis Treatment Insights

    Based on Treatment, the  Avascular Necrosis market segmentation includes trauma-related nonsteroidal anti-inflammatory drugs (NSAIDs), cholesterol lowing drugs, osteoporosis drugs, blood thinners, and others. The cholesterol lowing drugs segment dominated the market. This increase is related to the possibility that reducing blood fat and cholesterol levels could prevent arterial blockages that cause avascular necrosis.

    Avascular Necrosis Diagnosis Insights

    Based on diagnosis, the  Avascular Necrosis market segmentation includes imaging, biopsy, CT Scan, PET and X-Ray. The CT scan segment dominated the market. The more accurate test for avascular necrosis diagnosis is CT scan, which is substantially more accurate than simple film radiography in detecting AVN. An in-depth view of the bone is provided by the CT scan, which produces 3D images of the bone. Compared to other diagnostic procedures, it provides a more accurate and conclusive diagnosis of a bone problem. The most common and effective procedure is hence MRI and CT scanning.

    Avascular Necrosis End User Insights

    Based on end users, the  Avascular Necrosis market segmentation includes hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment generated the most income (54%). The segment growth is fueled by the rising need for minimally invasive care and reliance on surgery to address osteonecrosis. Additionally, the market is being driven ahead by regional governments' improvements to the healthcare infrastructure and an increase in hospitalization options. 

    Figure 1  Avascular Necrosis Market, by End User, 2023 & 2032 (USD Billion)

    Source Secondary Research, Primary Research, MRFR Database and Analyst Review

    Get more detailed insights about Avascular Necrosis Market Research Report – Forecast to 2032

    Regional Insights

    By region, the study provides market insights into North America, Europe, Asia-Pacific and the Rest of the World. The North American Avascular Necrosis market area will dominate this market because it places a greater emphasis on the relevance of avascular necrosis in persons and accepts cutting-edge therapeutic techniques with greater frequency. The public's focus on avascular necrosis medical conditions and diagnostics in this area and the expanding senior population will likely drive the market's growth.

    Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

    Figure 2  AVASCULAR NECROSIS MARKET SHARE BY REGION 2023 (USD Billion)AVASCULAR NECROSIS MARKET SHARE BY REGION 2022

    Source Secondary Research, Primary Research, MRFR Database and Analyst Review

    Europe's Avascular Necrosis market accounts for the second-largest market share, the large population's presence, and the rising number of people with Avascular Necrosis. Further, the German Avascular Necrosis market held the largest market share, and the UK Avascular Necrosis market was the fastest-growing market in the European region.

    Between 2023 and 2032, the Asia-Pacific Avascular Necrosis Market is anticipated to see the fastest CAGR growth. Increasing the number of people with avascular necrosis, government initiatives to enhance public awareness, and a rise in demand for the therapy fuel the market's revenue growth. In addition, the Indian Avascular Necrosis market had the quickest growth rate in the Asia-Pacific region, while China's Avascular Necrosis market had the highest market share.

    Key Players and Competitive Insights

    Leading industry companies are making significant R&D investments to diversify their product offerings, which will drive the Avascular Necrosis market's expansion. Important market developments include new product releases, contractual agreements, mergers and acquisitions, greater investments, and collaboration with other organizations. Market participants also engage in several strategic actions to increase their worldwide presence. The Avascular Necrosis industry must provide affordable products to grow and thrive in a more competitive and challenging market environment.

    Local manufacturing to cut operating costs is one of the key business tactics manufacturers use in the  Avascular Necrosis industry to help clients and expand the market sector In recent years, the Avascular Necrosis industry has offered some of the most significant advantages to medicine. Major players in the Avascular Necrosis market, including Dr. Reddy’s Laboratories Ltd., and others, are attempting to increase market demand by investing in research and development operations.

    Dr. Reddy's Laboratories Ltd. is an integrated pharmaceutical firm dedicated to offering cost-effective and cutting-edge medications for better lifestyles. Dr. Reddy offers a variety of goods and services, such as APIs, specialized pharmaceutical services, generics, biosimilars, and differentiated formulations, through its three companies, Pharmaceutical Services & Active Ingredients,  Generics, and Proprietary Products. Our primary therapeutic areas of interest are dermatology, cancer, diabetology, gastroenterology, and diabetology. Dr. Reddy has markets all over the world. The principal markets include the United States, India, the CIS nations, and Europe. 

    In August 2021 As permitted by the U.S. Food and Drug Administration (USFDA), Dr. Reddy's Laboratories Ltd. declared the re-launch of OTC (over-the-counter) Naproxen Sodium Pills USP, 220 mg, the store-brand comparable of Aleve®, in the U.S. market.

    Swiss and Americans founded Novartis AG. Novartis was the fourth largest by sales in 2022 and has consistently been rated in the top five ly. The Novartis Group is run by Novartis AG, a publicly traded Swiss holding corporation. Novartis AG directly or indirectly owns all businesses that function as subsidiaries of the Novartis Group ly. Three operating divisions make up Novartis's businesses Sandoz (generics), Innovative Medicines, and Alcon (eyecare).

    In October 2020, Leqvio (inclisiran) has been approved by the European Commission (EC) for treating people with hypercholesterolemia or mixed dyslipidemia, according to a statement from Novartis. This approval is based on the strong ORION clinical development program's findings, which showed that Leqvio reduced low-density lipoprotein cholesterol (LDL-C) in individuals with increased LDL-C by up to 52% while still maximally tolerated by statin therapy. Leqvio is anticipated to support long-term adherence with two doses per year, after an initial dose and one at three months 1-3.

    Key Companies in the Avascular Necrosis Market market include

    Future Outlook

    Avascular Necrosis Market Future Outlook

    The Global Avascular Necrosis Market is projected to grow at a 5.72% CAGR from 2025 to 2035, driven by advancements in treatment options, increasing prevalence, and rising awareness.

    New opportunities lie in:

    • Develop innovative drug delivery systems targeting avascular necrosis.
    • Expand telemedicine services for remote patient monitoring and consultations.
    • Invest in regenerative medicine technologies to enhance bone repair and recovery.

    By 2035, the market is expected to demonstrate robust growth, reflecting advancements in treatment and increased patient access.

    Market Segmentation

    Avascular Necrosis Type Outlook

    • Trauma Related Avascular Necrosis (AVN)
    • Non-Trauma Related Avascular Necrosis (AVN)

    Avascular Necrosis End user Outlook

    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies

    Avascular Necrosis Regional Outlook

    • US
    • Canada
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    • Middle East
    • Africa
    • Latin America

    Avascular Necrosis Diagnosis Outlook

    • Imaging
    • Biopsy
    • CT Scan
    • PET
    • X- Ray

    Avascular Necrosis Treatment Outlook

    • Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)
    • Cholesterol Lowing Drugs
    • Osteoporosis Drugs
    • Blood Thinners
    • Others

    Report Scope

    Avascular Necrosis Report Scope

    Report Attribute/Metric Details
    Market Size 2024 USD 0.564 Billion
    Market Size 2035 1.04 (Value (USD Billion))
    Compound Annual Growth Rate (CAGR) 5.72% (2025 - 2035)
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2018- 2022
    Market Forecast Units Value (USD Billion)
    Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments Covered Type, Treatment End User, and Region
    Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
    Countries Covered The US, Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
    Key Companies Profiled Novartis AGPfizer Inc.Teva Pharmaceutical Industries Ltd.Mylan N.V.Zimmer Biomet Merck & Co. Inc.Enzo Biochem Inc.Atnahs Bone Therapeutics SAVericel Corporation
    Key Market Opportunities Growing technology
    Key Market Dynamics Increase in fatal accidents
    Market Size 2025 0.60 (Value (USD Billion))

    Market Highlights

    Author
    Kinjoll Dey
    Research Analyst Level I

    He is an extremely curious individual currently working in Healthcare and Medical Devices Domain. Kinjoll is comfortably versed in data centric research backed by healthcare educational background. He leverages extensive data mining and analytics tools such as Primary and Secondary Research, Statistical Analysis, Machine Learning, Data Modelling. His key role also involves Technical Sales Support, Client Interaction and Project management within the Healthcare team. Lastly, he showcases extensive affinity towards learning new skills and remain fascinated in implementing them.

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    FAQs

    How much is the Avascular Necrosis market?

    The Avascular Necrosis market size was valued at USD 0.53 Billion in 2023.

    What is the growth rate of the Avascular Necrosis market?

    The market is projected to grow at a CAGR of 5.72% during the forecast period, 2024-2032.

    Which region held the largest market share in the Avascular Necrosis market?

    North America had the largest share in the market

    Who are the key players in the Avascular Necrosis market?

    The key players in the market are Novartis AGPfizer Inc.Teva Pharmaceutical Industries Ltd.Mylan N.V.Zimmer Biomet Merck & Co. Inc..

    Which type led the Avascular Necrosis market?

    The Non-Trauma Related Avascular Necrosis (AVN) dominated the market in 2022.

    Which end user had the largest market share in the Avascular Necrosis market?

    The hospital pharmacies had the largest share in the market.

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