Growing concern about the use of nucleic acid therapies to address hereditary and chronic conditions is driving the market growth
The potential of nucleic acid medicines to cure hereditary and chronic illnesses is driving up demand for them. DNA and RNA are examples of nucleic acids, which are vital molecules that are crucial for controlling gene expression and protein synthesis in cells. Furthermore, market growth will be fueled by an increase in the number of nucleic acid therapies approved by the FDA or the European Medicines Agency (EMA). In recent years, there has been a notable surge in the approval and development of nucleic acid medicines, encompassing RNA and DNA-based treatments.
Technology advancements and our growing understanding of the genetic pathways behind many diseases are partly to blame for this. For example, Onpattro (patisiran), a small interfering RNA (siRNA) therapy, has been approved as a nucleic acid therapeutic for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR). The FDA approved this treatment for RNA interference (RNAi) for the first time in 2018.
CDMOs can use a number of recent developments in manufacturing technology to increase productivity and cut expenses. The application of continuous manufacturing techniques is one such development. Instead of batch processing, which can be labor-intensive and need a large quantity of equipment, this method runs reactions in a continuous flow. Large amounts of starting materials and reagents are not required as frequently in continuous manufacturing, which also enables quicker processing times. The use of automated technologies for the purification and analysis of nucleic acids is another development.
Automation can help to lower expenses, boost efficiency, and decrease errors while also increasing accuracy. Additionally, by enhancing the scalability of nucleic acid manufacturing, these systems can let CDMOs generate vast amounts of nucleic acids for research or commercial purposes. Thus, driving the nucleic acid therapeutics market revenue.
The ongoing advancements in nucleic acid therapeutics are poised to revolutionize treatment paradigms across various diseases, reflecting a growing commitment to innovative healthcare solutions in Europe.
European Medicines Agency (EMA)