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    Microbiome Sequencing Services Market

    ID: MRFR/HC/6063-HCR
    160 Pages
    Rahul Gotadki
    October 2025

    Microbiome Sequencing Services Market Research Report Information By Technology (Sequencing by Litigation (SBL), Sequencing by Synthesis (SBS), Short Gun Sequencing, Targeted Gene Sequencing, RNA Sequencing, and Others), By Application (Gastrointestinal Diseases, Infectious Diseases, CNS Diseases, Oncology, and Others), and By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2035

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    Microbiome Sequencing Services Market Infographic
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    Microbiome Sequencing Services Market Summary

    The Global Microbiome Sequencing Services Market is projected to grow from 2.08 USD Billion in 2024 to 12.51 USD Billion by 2035.

    Key Market Trends & Highlights

    Microbiome Sequencing Services Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 16.99% from 2025 to 2034.
    • By 2035, the market valuation is anticipated to reach 11.7 USD Billion, indicating robust growth potential.
    • in 2024, the market is valued at 2.08 USD Billion, reflecting a strong foundation for future expansion.
    • Growing adoption of microbiome sequencing services due to increasing research in personalized medicine is a major market driver.

    Market Size & Forecast

    2024 Market Size 2.08 (USD Billion)
    2035 Market Size 12.51 (USD Billion)
    CAGR (2025-2035) 17.70%

    Major Players

    Rancho Biosciences, Metabiomics Corp., EPIBIOME, Baseclear B.V, Microbiome Therapeutics, LLC., Microbiome Insights Inc., Clinical Microbiomics A/S, Merieux Nutrisciences Corporations, Second Genome, Ubiome, Inc., Zymo Research Corp.

    Microbiome Sequencing Services Market Trends

    Rising price of sequencing infrastructure is driving the market growth

    Market CAGR for microbiome sequencing services is being driven by the rising price of the advanced infrastructure of sequencing. Next-generation sequencing (NGS) systems, bioinformatics tools, and data storage and analysis capabilities are just a few examples of the sophisticated and pricy technology needed for the field of microbiome sequencing. Many academic and research institutions, pharmaceutical and biotechnology firms, and other end users may find the expense of setting up and maintaining such infrastructure exorbitant. Microbiome sequencing outsourcing enables professionals to access cutting-edge technology and know-how without making substantial upfront investments.

    These service providers frequently feature cutting-edge facilities and knowledgeable staff adept at microbiome sequencing utilizing the most recent tools and techniques. Professionals can utilize the skills of these specialized facilities through outsourcing without having to worry about capital costs, operational costs, and maintenance costs related to in-house infrastructure.

    The market for microbiome sequencing services is expected to grow due to significant investments in microbiome research. Demand for next-generation sequencing services and genetic research has increased, which is anticipated to benefit the industry. The range of applications for microbiome sequencing is also expanding. The next-generation sequencing technologies show a fundamental shift in the sequencing industry. This technological know-how has been applied to biological study, leading to a surprising and profound grasp of the molecular biology of the cell. Budgets for research and development initiatives have steadily increased over the past ten years.

    Every pharmaceutical company wants its products to be successful on the market.

    The substantial virus research conducted by the government in collaboration with business stakeholders also contributed to the pandemic's high demand for microbiome sequencing. In the UK, a genome sequencing collaboration was established in March 2020 to enable quick, thorough, and extensive sequencing examination of samples from individuals whose COVID-19 testing was positive. The network will sequence every patient sample that tested positive for the virus. Oxford Nanopore is happy to support the teams in the UK working on this effort. Thus, driving the microbiome sequencing services market revenue.

    The increasing recognition of the microbiome's role in health and disease is driving a surge in demand for microbiome sequencing services, which are poised to revolutionize personalized medicine and therapeutic strategies.

    National Institutes of Health (NIH)

    Microbiome Sequencing Services Market Drivers

    Market Growth Projections

    The Global Microbiome Sequencing Services Market Industry is projected to witness substantial growth over the coming years. The market is expected to reach 2.08 USD Billion in 2024 and is forecasted to expand to 11.7 USD Billion by 2035. This growth trajectory suggests a compound annual growth rate of 16.99% from 2025 to 2035. Such projections indicate a robust demand for microbiome sequencing services, driven by advancements in technology, increased research funding, and a growing consumer focus on health and wellness.

    Increased Research Funding

    The Global Microbiome Sequencing Services Market Industry benefits from increased funding for microbiome research from both public and private sectors. Governments and research institutions are recognizing the potential of microbiome studies in various fields, including medicine, agriculture, and environmental science. This influx of funding is facilitating large-scale studies and collaborations, thereby expanding the scope of microbiome research. As a result, the demand for sequencing services is expected to rise, contributing to a compound annual growth rate of 16.99% from 2025 to 2035.

    Growing Awareness of Gut Health

    There is a growing awareness of the importance of gut health among consumers, which is significantly influencing the Global Microbiome Sequencing Services Market Industry. As individuals become more informed about the link between gut microbiota and overall health, they are increasingly seeking microbiome testing services. This trend is reflected in the rising number of companies offering consumer-oriented microbiome sequencing services. The increasing consumer demand for gut health insights is likely to drive market expansion, as more individuals seek personalized recommendations based on their microbiome profiles.

    Advancements in Sequencing Technologies

    Technological advancements in sequencing methodologies are propelling the Global Microbiome Sequencing Services Market Industry forward. Innovations such as next-generation sequencing (NGS) and single-cell sequencing are enhancing the accuracy and efficiency of microbiome analysis. These technologies enable researchers and clinicians to obtain comprehensive microbial profiles, which are essential for understanding complex interactions within the microbiome. As these technologies continue to evolve, they are likely to attract more investments and drive market growth, potentially leading to a market size of 11.7 USD Billion by 2035.

    Rising Demand for Personalized Medicine

    The Global Microbiome Sequencing Services Market Industry is experiencing a notable increase in demand for personalized medicine. This trend is largely driven by the growing recognition of the microbiome's role in health and disease. As healthcare providers seek to tailor treatments based on individual microbiome profiles, the market is projected to reach 2.08 USD Billion in 2024. This shift towards personalized healthcare solutions indicates a significant opportunity for microbiome sequencing services, as they provide critical insights that can enhance therapeutic efficacy and patient outcomes.

    Regulatory Support for Microbiome Research

    Regulatory bodies are increasingly supporting microbiome research, which is positively impacting the Global Microbiome Sequencing Services Market Industry. Initiatives aimed at promoting microbiome studies and establishing guidelines for microbiome-based products are fostering a conducive environment for innovation. This regulatory support not only encourages research but also enhances public trust in microbiome-related products and services. As regulations evolve, they may facilitate market entry for new players and technologies, further stimulating growth in the microbiome sequencing services sector.

    Market Segment Insights

    Microbiome Sequencing Services Market Segment Insights

    Microbiome Sequencing Services Technology Insights

    The microbiome sequencing services market segmentation, based on technology, includes sequencing by litigation (SBL), sequencing by synthesis (SBS), short gun sequencing, targeted gene sequencing, RNA sequencing, and others. The sequencing by synthesis (SBS)segment dominated the market, accounting for 42.1% of market revenue (0.6 Billion). SBS makes analyzing the microbiome efficient and affordable by concurrently enabling high-throughput sequencing of millions of DNA fragments. Shotgun sequencing applications are used in market segments that are the fastest growing segment. The industry is experiencing increased demand due to its prevalence and the need for efficient treatment methods.

    The shotgun accelerates the market's growth rate because it is more practical and affordable than any alternative option.

    Figure 1: Microbiome Sequencing Services Market, by Technology, 2022 & 2034 (USD Billion)

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Microbiome Sequencing Services Application Insights

    The microbiome sequencing services market segmentation, based on application, includes gastrointestinal diseases, infectious diseases, cns diseases, oncology, and others. The oncology sector dominates the market for microbiome sequencing services. Because of the increasing number of cancer cases worldwide and the growth of cancer genomic research, the market for microbiome sequencing services is predicted to increase.

    March 2022: Microbiotica has raised USD 67 million for its study on microbiome-based immuno-oncology, which will begin later this year. Microbiotica's two lead oral Live Bacterial Therapeutics (LBTs), MB097 and MB310, will be advanced to Phase 1b clinical trials with the funds. MB097 is a fully characterized LBT comprising a consortium of bacteria that form the foundation of Microbiotica's clinical microbiome signature that predicts patient response to Immune Checkpoint Inhibitor medication.

    A significant share belonged to the gastrointestinal area. Various gut-related disorders can result from changes in the microbiome, which is crucial for maintaining the health of the digestive system. Researchers have uncovered important microbial species and their roles in the emergence and progression of gut-related disorders thanks to using microbiome sequencing to analyze the gut microbiome.

    Get more detailed insights about Microbiome Sequencing Services Market Research Report – Forecast till 2034

    Regional Insights

    By region, the report gives market insights into North America, Europe, Asia-Pacific and Rest of the World. The North American microbiome sequencing services market will dominate due to the rise in the adoption of highly advanced techniques and systems in the microbiome sequencing services and technical improvements made in genomic research investigations. The strong market growth in the region is mostly due to the high awareness among medical professionals about the existence of cutting-edge microbiome sequencing services in the market.

    Further, the major countries studied in the market report are US, Canada, France, German, Italy, UK, Spain, Japan, China, Australia, India, South Korea, and Brazil.

    Figure 2: MICROBIOME SEQUENCING SERVICES MARKET SHARE BY REGION 2022 (USD Billion)

    MICROBIOME SEQUENCING SERVICES MARKET SHARE BY REGION 2022

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Europe’s microbiome sequencing services market accounts for the second-largest market share. Significant players' presence and increased public awareness of NGS are important drivers of accelerating expansion. The increased use of micro-biomes in genomes, proteomics, and metabolomics is responsible for this region's expansion. Further, the German microbiome sequencing services market held the largest market share, and the UK microbiome sequencing services market was the rapidly growing market in the European region.

    The Asia-Pacific Microbiome Sequencing Services Market is expected to grow at a rapid rate from 2023 to 2034. Due to several causes, including increased research funding, increased interest in personalized treatment, and expanding government initiatives to construct cutting-edge healthcare infrastructure, the region's demand for microbiome sequencing services is on the rise. The continual advancement of sequencing technologies and the introduction of novel methods for disease diagnosis are credited with this region's expansion. Moreover, China’s microbiome sequencing services market held the largest market share, and the Indian microbiome sequencing services market was the rapidly growing market in the Asia-Pacific region.

    Key Players and Competitive Insights

    Leading market players are investing heavily in research and development to expand their product lines, which will help the microbiome sequencing services market, grow even more. To increase their worldwide footprint, market participants are also engaging in various strategic actions. Important market developments include introducing new products, mergers and acquisitions, contractual agreements, increased investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, the microbiome sequencing services industry must offer cost-effective items.

    Manufacturing locally to minimize operational costs is one of the key business tactics manufacturers use in the microbiome sequencing services industry to benefit clients and increase the market sector. In recent years, the microbiome sequencing services industry has offered some of the most significant medical advantages. Major players in the microbiome sequencing services market, including Rancho Biosciences, Metabiomics Corp., EPIBIOME, Baseclear B.V, Microbiome Therapeutics, LLC., and others, are attempting to increase market demand by investing in research and development operations.

    Microba Life Sciences Ltd is a commercial-stage firm that uses cutting-edge technology to measure the human gut microbiota and provides gut microbiome testing services to consumers, doctors, and researchers worldwide. Testing Services and Research and Development are two of the company's segments. In February 2023, Microba created a new human gut microbiome testing service to provide comprehensive gastrointestinal testing options. The new human gut microbiome testing product range, launched in Australia, delivers diagnostic gastrointestinal health testing and metagenomic-driven gut microbiome analysis to provide healthcare practitioners with comprehensive gastrointestinal testing solutions.

    OraSure Technologies develops, manufactures, and distributes oral fluid diagnostic and collecting systems. Diagnostics and molecular solutions are its reportable segments. The diagnostics branch creates rapid oral diagnostic tests and tools for collecting samples for infectious diseases, including HIV and HCV. In March 2022, OraSure Technologies, Inc. introduced a new service to deliver metatranscriptomic sequencing and analysis of gut microbiome samples through its Diversigen subsidiary.

    The metatranscriptomic services will build a gene expression profile of a microbial community to inform clients about the interactions between a human and their microbiome and provide a comprehensive picture of a sample's microbial functions and expression levels.

    Key Companies in the Microbiome Sequencing Services Market market include

    Industry Developments

    January 2022:Eagle Genomics and Quadram Institute have formed a new strategic alliance to speed up microbiome analysis using an AI-augmented knowledge discovery platform and genetic sequencing technology. The collaboration with the Quadram Institute will involve the sharing of datasets, tools, and innovation pipelines to aid in the understanding of complex microbiome data through Eagle Genomics' e[datascientist] platform, building on the agreement with the Earlham Institute, a Norwich-based leader in data-intensive bioscience research.

    June 2021:Illumina and Microba Life Sciences have formed a collaboration to better study the role of the human gut microbiome in human health and illness. The collaboration will combine Illumina's ground-breaking NGS techniques with Microba's high-quality proprietary gut microbiome analysis platform to generate the precise metagenomic data researchers need to fuel new discoveries.

    Future Outlook

    Microbiome Sequencing Services Market Future Outlook

    The Microbiome Sequencing Services Market is projected to grow at a 17.70% CAGR from 2024 to 2034, driven by advancements in personalized medicine, increasing research funding, and rising consumer awareness.

    New opportunities lie in:

    • Develop innovative microbiome-based therapeutics targeting chronic diseases.
    • Expand service offerings to include direct-to-consumer microbiome testing.
    • Leverage AI for enhanced data analysis and interpretation in microbiome research.

    By 2035, the market is expected to reach substantial growth, reflecting its critical role in healthcare innovation.

    Market Segmentation

    Microbiome Sequencing Services Regional Outlook

    • US
    • Canada
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    • Middle East
    • Africa
    • Latin America

    Microbiome Sequencing Services Technology Outlook

    • Sequencing by Litigation (SBL)
    • Sequencing by Synthesis (SBS)
    • Short Gun Sequencing
    • Targeted Gene Sequencing
    • RNA Sequencing
    • Others

    Microbiome Sequencing Services Application Outlook

    • Gastrointestinal Diseases
    • Infectious Diseases
    • CNS Diseases
    • Oncology
    • Others

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024    2.08 (USD Billion)
    Market Size 2025    2.45 (USD Billion)
    Market Size 2035 12.51 (USD Billion)
    Compound Annual Growth Rate (CAGR) 17.70% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2020 - 2024
    Report Coverage Market Competitive Landscape, Revenue Forecast, Growth Factors, and Trends
    Segments Covered Technology and Application
    Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
    Countries Covered US, Canada, France, German, Italy, UK, Spain, Japan, China, Australia, India, South Korea, and Brazil.
    Key Companies Profiled Rancho Biosciences, Metabiomics Corp., EPIBIOME, Baseclear B.V, and Microbiome Therapeutics, LLC.
    Key Market Opportunities Expanding applications of microbiome sequencing in therapeutics development
    Key Market Dynamics Increasing demand for metagenomic sequencing

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the projected growth of the Microbiome Sequencing Services market?

    The Microbiome Sequencing Services market is the expected increase in total market value of 12.51 USD billion over a defined forecast period 2025–2035. It is driven by factors such as demand trends, technological advances, regulatory changes, and geographic expansion.

    What is the size of the Microbiome Sequencing Services market?

    Microbiome Sequencing Services market size was valued at approximately 2.08 billion USD in 2024. This figure will reach 12.51 billion USD covering all regions (America, Europe, Asia, MEA and ROW), focusing its segments / services / distribution channels till 2035.

    What is the CAGR of the Microbiome Sequencing Services market?

    Microbiome Sequencing Services market is expected to grow at a CAGR of 17.7% between 2025 and 2035.

    How much will the Microbiome Sequencing Services market be worth by 2035?

    Microbiome Sequencing Services market is expected to be worth of 12.51 billion USD, reflecting growth driven by usage, technology and global demands by the end of 2035.

    How will the Microbiome Sequencing Services market perform over the next 10 years?

    Over the next 10 years the Microbiome Sequencing Services market is expected to shift from usd billion 2.08 to 12.51 billion USD, led by adoption of advanced tech, demographic trends, regulatory approvals, with potential headwinds from 2025 to 2035.

    Which region held the major market share in the microbiome sequencing services market?

    North America had the largest share of the market.

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