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    Microbiome Therapeutic Market

    ID: MRFR/HC/41788-HCR
    200 Pages
    Garvit Vyas
    September 2025

    Microbiome Therapeutic Market Research Report By Application (Infectious Diseases, Metabolic Diseases, Autoimmune Diseases, Oncology, Neurological Disorders), By Product Type (Probiotics, Prebiotics, Synbiotics, Live Microorganisms, Fecal Microbiota Transplant), By Route of Administration (Oral, Intravenous, Topical, Rectal), By End User (Hospitals, Clinics, Homecare Settings, Research Laboratories) andBy Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa)- Forecast to 2035

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    Microbiome Therapeutic Market Summary

    The Global Microbiome Therapeutic Market is projected to grow from 5.41 USD Billion in 2024 to 12.5 USD Billion by 2035, reflecting a robust growth trajectory.

    Key Market Trends & Highlights

    Microbiome Therapeutic Key Trends and Highlights

    • The market is expected to achieve a compound annual growth rate (CAGR) of 7.91% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 12.5 USD Billion, indicating a substantial increase from the base year.
    • In 2024, the market is valued at 5.41 USD Billion, highlighting the current investment landscape in microbiome therapeutics.
    • Growing adoption of microbiome-based therapies due to increasing prevalence of chronic diseases is a major market driver.

    Market Size & Forecast

    2024 Market Size 5.41 (USD Billion)
    2035 Market Size 12.5 (USD Billion)
    CAGR (2025-2035) 7.91%

    Major Players

    Synlogic, Amgen, Ferring Pharmaceuticals, Mikrobio, Havencrest Capital, Medosome Biotec, Zymeworks, 2seventy bio, AOBiome, Eden Biosciences, AbbVie, Diverse Biotech, Microbiotica, Enterome, Seres Therapeutics

    Microbiome Therapeutic Market Trends

    The Global Microbiome Therapeutic Market is experiencing significant growth driven by several key factors. The increasing prevalence of chronic diseases, combined with a rising understanding of the microbiome's role in human health, has fueled demand for innovative microbiome-based treatments.

    The rise in research and development activities is enhancing product offerings, with collaborations between academic institutions and pharmaceutical companies paving the way for new therapeutic solutions. Furthermore, an increasing focus on personalized medicine highlights the potential of microbiome therapeutics to offer tailored treatments based on individual microbiome profiles.

    There is a plethora of opportunities within the market, especially in positive niches such as autoimmune diseases, gastrointestinal disorders, and issues pertaining to mental health. Added to this, there is an increased exploration of the link between microbiome and obesity or diabetes, which provides new intervention opportunities.

    With the primary focus shifting to preventative healthcare, a vast segment of the market can be targeted with microbiome-promoting products. More so, regulatory processes towards the approval of microbiome therapeutics have relaxed, offering better efficiency and access to these advanced treatment options. 

    Recent trends indicate a surge in consumer awareness regarding gut health and its importance in overall well-being. This shift is leading to increased acceptance of probiotics and other microbiome-related products. Additionally, advancements in technology, such as genomic sequencing and metabolomics, are paving the way for more precise and effective microbiome therapies.

    Greater emphasis on research, adoption of microbiome diagnostics, and increasing investments in clinical trials reflect a dynamic market landscape where ongoing innovations are likely to reshape therapeutic options, providing both challenges and significant growth prospects in the near future.

    The Global Microbiome Therapeutic Market is poised for transformative growth, driven by increasing recognition of the microbiome's role in health and disease management, alongside advancements in biotechnological research.

    National Institutes of Health (NIH)

    Microbiome Therapeutic Market Drivers

    Market Growth Projections

    The Global Microbiome Therapeutic Market Industry is poised for substantial growth, with projections indicating a rise from 5.41 USD Billion in 2024 to 12.5 USD Billion by 2035. This growth trajectory suggests a compound annual growth rate (CAGR) of 7.91% from 2025 to 2035. Such figures reflect the increasing recognition of the microbiome's role in health and disease, driving investment and innovation in this field. The anticipated expansion of the market underscores the potential for microbiome therapeutics to revolutionize treatment paradigms across various health conditions.

    Advancements in Microbiome Research

    Ongoing advancements in microbiome research are propelling the Global Microbiome Therapeutic Market Industry forward. Innovations in sequencing technologies and bioinformatics are enabling researchers to better understand the complex interactions within the microbiome. This deeper understanding facilitates the development of targeted therapies that can modulate the microbiome for therapeutic benefit. As research continues to unveil the microbiome's influence on health and disease, the industry is likely to see an influx of novel products. The anticipated growth from 5.41 USD Billion in 2024 to 12.5 USD Billion by 2035 underscores the importance of research in driving market expansion.

    Growing Consumer Awareness and Demand

    Consumer awareness regarding the health benefits of microbiome modulation is rising, significantly impacting the Global Microbiome Therapeutic Market Industry. As individuals become more informed about the connection between gut health and overall well-being, there is an increasing demand for products that support microbiome health. This trend is evident in the growing popularity of probiotics and prebiotics, which are often marketed as essential for maintaining a healthy microbiome. The market's growth from 5.41 USD Billion in 2024 to an expected 12.5 USD Billion by 2035 reflects this heightened consumer interest and the potential for new product development in the microbiome space.

    Increased Investment in Biotechnology

    The surge in investment within the biotechnology sector is a crucial driver for the Global Microbiome Therapeutic Market Industry. Venture capital and government funding are increasingly directed towards microbiome research and development, fostering innovation and accelerating the commercialization of microbiome-based therapies. This influx of capital supports clinical trials and the development of new products, enhancing the industry's growth potential. With the market projected to grow from 5.41 USD Billion in 2024 to 12.5 USD Billion by 2035, the financial backing is likely to facilitate the emergence of groundbreaking therapies that leverage microbiome science.

    Rising Prevalence of Chronic Diseases

    The increasing prevalence of chronic diseases globally is a significant driver for the Global Microbiome Therapeutic Market Industry. Conditions such as obesity, diabetes, and inflammatory bowel diseases are becoming more common, prompting a search for innovative treatment options. The microbiome's role in these diseases is gaining recognition, leading to increased investment in microbiome-based therapies. As of 2024, the market is valued at approximately 5.41 USD Billion, with projections indicating growth to 12.5 USD Billion by 2035. This trend suggests a compound annual growth rate (CAGR) of 7.91% from 2025 to 2035, highlighting the potential for microbiome therapeutics to address these pressing health issues.

    Regulatory Support for Microbiome Therapies

    Regulatory bodies are increasingly recognizing the potential of microbiome therapies, providing a supportive framework for the Global Microbiome Therapeutic Market Industry. Initiatives aimed at streamlining the approval process for microbiome-based products are emerging, which may encourage more companies to invest in this area. This regulatory support could lead to faster market entry for innovative therapies, enhancing competition and diversity within the market. As the industry anticipates growth from 5.41 USD Billion in 2024 to 12.5 USD Billion by 2035, favorable regulatory conditions are likely to play a pivotal role in shaping the future landscape of microbiome therapeutics.

    Market Segment Insights

    Microbiome Therapeutic Market Application Insights

    The Global Microbiome Therapeutic Market, particularly in the Application segment, demonstrates a progressive landscape influenced by the growing recognition of the microbiome's role in health and disease management. By 2024, the market is expected to be valued at 5.41 USD Billion, highlighting significant opportunities across various application areas. Infectious Diseases lead this sector with a valuation of 1.62 USD Billion in 2024, reflecting a crucial focus given the rising global burden of infections and the need for effective therapeutic solutions.

    Metabolic Diseases follow closely with a projected value of 1.08 USD Billion in the same year, showcasing the critical link between microbiome health and metabolic regulation, influencing conditions such as obesity and diabetes which are prevalent in today's society. 

    Autoimmune Diseases account for a market value of 0.85 USD Billion in 2024, pointing to the growing interest in microbiome therapies as potential adjuncts to traditional treatment, addressing the immune system's complex interactions with microbial communities. Oncology represents an emerging field with a valuation of 1.21 USD Billion, signifying the potential of microbiome-based therapies to enhance cancer treatment outcomes through modulation of the immune system and tumor microenvironment.

    Neurological Disorders, though currently valued at 0.65 USD Billion, signify a rapidly growing area of research, often gaining attention for the intriguing link between gut microbiota and brain health, thus opening new avenues for therapeutic applications.The diverse Applications of microbiome therapeutics illustrate a comprehensive landscape driven by market growth dynamics that address pressing health issues. Each application area presents unique challenges and growth drivers, shaped by increasing research efforts and investment in microbiome-related studies.

    Emerging technologies and a clearer understanding of microbiota's role in health and disease support this sector's evolution, alongside ongoing regulatory developments that may facilitate the approval and adoption of microbiome-based therapies. Growth opportunities lie in enhancing product pipelines and fostering collaborations between pharmaceutical companies and biotech firms to innovate and expand therapeutic offerings across these applications, which will be crucial in capitalizing on the evolving market landscape.

    Overall, the insights drawn from the Global Microbiome Therapeutic Market segmentation underscore significant potentials and trends that shape future developments in this field.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Microbiome Therapeutic Market Product Type Insights

    The Global Microbiome Therapeutic Market is projected to reach a valuation of 5.41 billion USD by 2024, with various product types contributing to its growth. Among these, Probiotics have gained significant traction due to their effectiveness in maintaining gut health and overall wellness. Prebiotics, on the other hand, play a crucial role in nourishing beneficial gut bacteria, thus fostering a healthy microbiome. Synbiotics combine both probiotics and prebiotics, enhancing their therapeutic effects, which makes them a popular choice among consumers.

    Live Microorganisms contribute to the diversity and balance of gut flora, and their applications are expanding in clinical settings. Fecal Microbiota Transplant has emerged as a groundbreaking approach for treating specific gastrointestinal diseases, drawing interest from both healthcare providers and patients.

    The market growth in these areas is influenced by increasing consumer awareness, growing healthcare expenditures, and the rising prevalence of microbiome-related disorders. However, challenges such as regulatory hurdles and the need for precise scientific validation may impact market dynamics.As the industry continues to evolve, opportunities may arise from advancements in research and development, opening new avenues for innovative therapies within the microbiome space.

    Microbiome Therapeutic Market Route of Administration Insights

    The Global Microbiome Therapeutic Market has gained significant traction, particularly in the Route of Administration segment, which encompasses various delivery methods such as Oral, Intravenous, Topical, and Rectal. By 2024, the overall market was valued at approximately 5.41 billion USD, highlighting the growing importance of effective delivery mechanisms in enhancing therapeutic outcomes.

    The Oral route is particularly prominent due to its ease of use and patient compliance, leading to a major contribution to the market’s growth. Intravenous administration is critical for rapid therapeutic effects, especially in acute conditions, thereby holding a significant share.

    Topical applications are gaining attention as they provide localized treatment, addressing specific conditions without systemic effects. Rectal administration, although less common, remains crucial for certain patient demographics, including children and those with swallowing difficulties. Each of these routes plays a vital role in the market’s diversification and growth, catering to varied patient needs and preferences. As the demand for microbiome-based therapies increases, understanding the nuances of each administration route becomes essential for stakeholders aiming to enhance treatment effectiveness and achieve better patient outcomes.

    Microbiome Therapeutic Market End User Insights

    The Global Microbiome Therapeutic Market is poised for considerable growth, with a projected overall valuation of 5.41 billion USD by 2024. The End User segmentation of this market is critical for understanding the applications and demand across various healthcare settings. Hospitals represent a significant portion of the market, given their role in advanced medical care and chronic disease management, while clinics provide essential access to microbiome therapies in outpatient settings.

    Homecare settings are gaining traction due to increasing patient preference for localized healthcare solutions, enhancing the management of microbiome-related conditions in the comfort of patients' homes.Research laboratories also play a pivotal role in driving innovation through extensive studies on microbiome applications, thus influencing future treatments.

    The global Microbiome Therapeutic Market data reflects these trends, indicating that the diversity of End Users not only caters to varying patient needs but also opens up several opportunities for market growth. As the market develops, understanding these elements will be vital for stakeholders aiming to capitalize on the evolving dynamics of the Global Microbiome Therapeutic Market industry.

    Get more detailed insights about Microbiome Therapeutic Market Research Report — Global Forecast till 2034

    Regional Insights

    The Regional segment of the Global Microbiome Therapeutic Market shows significant variation in market valuations as it matures. In 2024, North America emerges as a dominant player, holding a valuation of 2.78 USD Billion, which is expected to rise to 6.32 USD Billion by 2035, indicating its majority holding in the overall market. Europe follows with a valuation of 1.6 USD Billion in 2024 and is projected to reach 3.66 USD Billion by 2035, making it a significant contributor.

    APAC, valued at 0.8 USD Billion in 2024, is expected to grow to 1.89 USD Billion, reflecting increasing investments in healthcare innovations.In contrast, South America and MEA are comparatively smaller, with valuations of 0.12 USD Billion and 0.11 USD Billion in 2024, respectively, growing to 0.28 USD Billion and 0.25 USD Billion by 2035.

    These regions face different challenges and opportunities, often relying on emerging research and increasing government support for microbiome-based therapies. Overall, the Global Microbiome Therapeutic Market segmentation highlights how regional dynamics influence growth trends, with North America and Europe demonstrating strong market potential owing to advances in biotechnology and therapeutic developments.

    Microbiome Therapeutic Market Region

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Global Microbiome Therapeutic Market is a rapidly evolving sector focused on leveraging the human microbiome to develop novel therapies for various diseases, including gastrointestinal disorders, autoimmune diseases, and metabolic conditions. The market's growth is driven by an increasing understanding of the complex interactions between microbiota and health, leading to the exploration of bioengineering microbiomes for therapeutic purposes. Key competitive insights indicate a landscape where biotechnology firms and pharmaceutical companies are intensely racing to innovate and bring microbiome-based therapies to market.

    With increasing investments in research and development, along with strategic collaborations between academic institutions and biotech firms, the ecosystem is characterized by a mix of established players and startups striving for market share in this promising field.Synlogic is a prominent player within the Global Microbiome Therapeutic Market, recognized for its pioneering work in developing innovative therapies based on engineered live microbes.

    The company specializes in the creation of synthetic biotics, which are designed to restore metabolic balance by targeting specific diseases. Its strengths lie in a robust pipeline of clinical programs aimed at treating rare metabolic disorders that derive from malfunctions in the microbiome. Synlogic's technology platform allows for customizable therapeutic solutions that adjust the microbial composition to deliver precise clinical benefits. 

    The company’s deep expertise in microbial engineering, coupled with a strong emphasis on clinical development, positions it well to capitalize on the growing demand for effective microbiome interventions. Synlogic's commitment to advancing healthcare through microbiome research places it at a competitive advantage within this niche market.

    Amgen is another significant entity in the Global Microbiome Therapeutic Market, leveraging its extensive experience in biotechnology to explore the potential of microbiome-based therapies. The company seeks to enhance its therapeutic portfolio by incorporating microbiome research, focusing on the links between gut health and systemic diseases. Amgen's established reputation in the biopharmaceutical space provides a significant advantage when exploring innovative treatment modalities that arise from microbiome insights.

    The firm's vast resources pave the way for comprehensive studies aimed at understanding the microbiome's role in various health conditions, thus enabling it to develop targeted therapies that can potentially improve patient outcomes. Through strategic partnerships and collaborations aimed at harnessing the power of microbiome research, Amgen positions itself as a key player in this burgeoning market, exhibiting a strong presence driven by its established capabilities and commitment to addressing unmet medical needs.

    Key Companies in the Microbiome Therapeutic Market market include

    Industry Developments

    • Q3 2025: In July 2025, Seres Therapeutics announced positive Phase 3 results for SER-155, an oral microbiome therapy to prevent infections in immunocompromised patients. Seres Therapeutics reported positive Phase 3 clinical trial results for SER-155, an oral microbiome therapeutic designed to prevent bloodstream infections in immunocompromised patients post-stem cell transplant. The company plans to submit for regulatory approval in the U.S. in early 2026.
    • Q2 2025: In June 2025, Vedanta Biosciences raised $105 million in Series D funding to advance its microbiome-derived cancer immunotherapy candidates. Vedanta Biosciences secured $105 million in Series D funding to support the development of its lead microbiome-derived immunotherapy asset VE800, which is being tested in combination with checkpoint inhibitors, and to expand its GMP manufacturing facility.

    Future Outlook

    Microbiome Therapeutic Market Future Outlook

    The Global Microbiome Therapeutic Market is projected to grow at a 7.91% CAGR from 2024 to 2035, driven by advancements in personalized medicine, increasing prevalence of microbiome-related diseases, and growing investment in microbiome research.

    New opportunities lie in:

    • Develop targeted microbiome therapies for chronic diseases to capture niche markets.
    • Leverage AI and machine learning for microbiome data analysis to enhance product development.
    • Establish partnerships with healthcare providers to integrate microbiome therapies into standard treatment protocols.

    By 2035, the market is expected to reach a robust position, reflecting substantial growth and innovation.

    Market Segmentation

    Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Microbiome Therapeutic Market End User Outlook

    • Hospitals
    • Clinics
    • Homecare Settings
    • Research Laboratories

    Microbiome Therapeutic Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Microbiome Therapeutic Market Application Outlook

    • Infectious Diseases
    • Metabolic Diseases
    • Autoimmune Diseases
    • Oncology
    • Neurological Disorders

    Microbiome Therapeutic Market Product Type Outlook

    • Probiotics
    • Prebiotics
    • Synbiotics
    • Live Microorganisms
    • Fecal Microbiota Transplant

    Microbiome Therapeutic Market Route of Administration Outlook

    • Oral
    • Intravenous
    • Topical
    • Rectal

    Report Scope

    Scope:
    Attribute/Metric Source: Details
    MARKET SIZE 2023 5.02(USD Billion)
    MARKET SIZE 2024 5.41(USD Billion)
    MARKET SIZE 2035 12.5(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 7.91% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2023
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED Synlogic, Amgen, Ferring Pharmaceuticals, Mikrobio, Havencrest Capital, Medosome Biotec, Zymeworks, 2seventy bio, AOBiome, Eden Biosciences, AbbVie, Diverse Biotech, Microbiotica, Enterome, Seres Therapeutics
    SEGMENTS COVERED Application, Product Type, Route of Administration, End User, Regional
    KEY MARKET OPPORTUNITIES Rising prevalence of gut disorders, Increasing demand for personalized medicine, Expanding applications in oncology treatments, Advancements in microbiome research technologies, Growing interest in preventive healthcare solutions
    KEY MARKET DYNAMICS Rising prevalence of chronic diseases, Increased investment in R&D, Growing consumer awareness, Advancements in microbiome research, Regulatory support for therapeutic development
    COUNTRIES COVERED North America, Europe, APAC, South America, MEA

    FAQs

    What is the expected market size of the Global Microbiome Therapeutic Market in 2024?

    The Global Microbiome Therapeutic Market is expected to be valued at 5.41 USD Billion in 2024.

    What will the projected market size be for the Global Microbiome Therapeutic Market by 2035?

    By 2035, the overall market is anticipated to reach a value of 12.5 USD Billion.

    What is the expected CAGR for the Global Microbiome Therapeutic Market from 2025 to 2035?

    The expected CAGR for the Global Microbiome Therapeutic Market from 2025 to 2035 is 7.91%.

    Which region will have the largest market share in 2024?

    North America is projected to have the largest market share, valued at 2.78 USD Billion in 2024.

    What is the projected market size for Infectious Diseases application by 2035?

    The market size for Infectious Diseases application is projected to be 3.76 USD Billion by 2035.

    Which company is among the major players in the Global Microbiome Therapeutic Market?

    Major players in the Global Microbiome Therapeutic Market include companies like AbbVie and Synlogic.

    What is the expected market value for Neurological Disorders application in 2024?

    The expected market value for Neurological Disorders application in 2024 is 0.65 USD Billion.

    What is the growth rate for the Europe region in the Global Microbiome Therapeutic Market?

    The European market is expected to grow from 1.6 USD Billion in 2024 to 3.66 USD Billion by 2035.

    What will be the market size for Autoimmune Diseases application by 2035?

    By 2035, the market size for Autoimmune Diseases application is projected to reach 1.98 USD Billion.

    How will the Oncology application market size evolve by 2035?

    The Oncology application market size is expected to reach 2.81 USD Billion by 2035.

    Microbiome Therapeutic Market Research Report — Global Forecast till 2034 Infographic
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