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    Myasthenia Gravis Market

    ID: MRFR/HC/5800-CR
    200 Pages
    Rahul Gotadki
    December 2024

    Myasthenia Gravis Market Research Report By Disease Type (Acetylcholine Receptor Antibody Positive Myasthenia Gravis, Muscle-Specific Kinase Antibody Positive Myasthenia Gravis, Seronegative Myasthenia Gravis), By Treatment Type (Anticholinesterase Agents, Immunosuppressants, Intravenous Immunoglobulin, Plasmapheresis, Thymectomy), By Route of Administration (Oral, Intravenous, Subcutaneous), By End User (Hospitals, Specialty Clinics, Homecare Settings) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Afri...

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    Myasthenia Gravis Market Summary

    As per Market Research Future Analysis, the Myasthenia Gravis Market was valued at 2.11 USD Billion in 2024 and is projected to grow to 4.5 USD Billion by 2035, with a CAGR of 7.11% from 2025 to 2035. The market is driven by increasing awareness, advancements in diagnostic technologies, and new treatment options, including monoclonal antibodies and personalized medicine approaches. The rise in autoimmune disorders and technological integration in healthcare further support market expansion.

    Key Market Trends & Highlights

    The Myasthenia Gravis Market is experiencing significant transformation driven by various trends.

    • Market Size in 2024: 2.11 USD Billion; Expected to reach 4.5 USD Billion by 2035.
    • Acetylcholine Receptor Antibody Positive Myasthenia Gravis segment projected to grow from 0.87 USD Billion in 2024 to 1.85 USD Billion by 2035.
    • Telehealth utilization has surged by over 50% since 2020, improving patient access to care.
    • Rising incidence of autoimmune disorders affects approximately 5 to 7% of the global population.

    Market Size & Forecast

    2023 Market Size USD 1.97 Billion
    2024 Market Size USD 2.11 Billion
    2035 Market Size USD 4.5 Billion
    CAGR (2025-2035) 7.11%

    Major Players

    Pfizer, Merck and Co, Grifols, Roche, Johnson and Johnson, UCB, Teva Pharmaceutical Industries, Eisai, Novartis, Mylan, Bristol-Myers Squibb, AstraZeneca, Alexion Pharmaceuticals, Amgen, Sanofi

    Myasthenia Gravis Market Trends

    The Myasthenia Gravis Market is changing significantly with emerging trends, the myasthenia gravis market is further propelled by the rising awareness and diagnostic capabilities supporting the growing incidence of the disease. Moreover, the market is being fueled by new treatment options such as new therapeutics and personalized medicine approaches which serve to enhance the overall patient outcomes. 

    As a result of these factors, there is innovation in many effective and efficient treatment options which improve the patient's quality and satisfaction to a greater extent. There are also emerging opportunities in the market as many stakeholders are realizing the potential for developing novel therapies which address the ignored medical needs.

    Myasthenia Gravis has a strong focus on research and development, collaborations of biotech companies with pharmaceutical companies along with other unfinished myasthenia gravis studies. These collaborations promote the development of new formulations and innovative drug delivery systems and other ways of managing myasthenia gravis. Growth of clinical trials in many regions also provides an opportunity for new therapies to be introduced and made available worldwide. Some recent trends focus more on the support programs for educative and patients conducted by hospitals and clinics. Providing information enables better control of the condition and contributes to the improve the overall life quality.

    There is an increase in the development of digital health tools designed to improve communication between patients and providers, as well as treatment adherence and monitoring. Remote patient care or telemedicine has also been adopted to expand care access to patients in more isolated areas. All these trends illustrate the steps being taken toward the Myasthenia Gravis Market, with particular emphasis being placed on the patients' needs.

    The Global Myasthenia Gravis Market is poised for growth as advancements in therapeutic options and increased awareness of the disease drive demand for innovative treatments.

    National Institutes of Health (NIH)

    Myasthenia Gravis Market Drivers

    Increasing Prevalence of Myasthenia Gravis

    The Global Myasthenia Gravis Market Industry is witnessing a notable increase in the prevalence of myasthenia gravis, a chronic autoimmune disorder characterized by weakness in the skeletal muscles. Current estimates suggest that the incidence rate is approximately 20 cases per 100,000 people, with a higher prevalence observed in women, particularly those aged 20 to 40. This rising incidence is likely to drive demand for innovative therapies and treatment options, contributing to the market's growth. As the population ages, the number of individuals affected by this condition is expected to rise, further emphasizing the need for effective management strategies within the Global Myasthenia Gravis Market Industry.

    Market Segment Insights

    Myasthenia Gravis Market Disease Type Insights

    The Myasthenia Gravis Market, particularly within the Disease Type segment, showcased a significant dynamic with a total market valuation of 2.11 USD Billion in 2024 and projected to grow substantially by 2035. This robust growth trajectory underscores the increasing awareness and advancements in treatment options for Myasthenia Gravis, driven by a surge in research initiatives and technological innovations. 

    Among the various classifications based on disease type, the Acetylcholine Receptor Antibody Positive Myasthenia Gravis is anticipated to dominate the segment, holding a valuation of 0.87 USD Billion in 2024, and expanding to 1.85 USD Billion by 2035. This segment's significance stems from its position as the most prevalent form of myasthenia gravis, which represents a majority holding in the overall market, prompting healthcare stakeholders to focus on developing targeted therapies and treatments. 

    In addition, the Muscle-Specific Kinase Antibody Positive Myasthenia Gravis segment is also substantial, with a valuation of 0.68 USD Billion in 2024 and expected to reach 1.43 USD Billion in 2035. The increasing recognition of this type and its unique treatment challenges have led to a marked demand for specialized healthcare solutions, ensuring that it maintains a vital role within the Myasthenia Gravis Market. 

    Furthermore, the Seronegative Myasthenia Gravis category, currently valued at 0.56 USD Billion in 2024 and projected to grow to 1.22 USD Billion by 2035, highlights the complexities associated with treatment and diagnosis in the absence of known antibodies. Despite being the least dominant in market value, the relevance of the Seronegative segment signals opportunities for enhanced research and development. The growing need for awareness and improved healthcare infrastructure presents opportunities for practitioners and researchers to delve deeper into the underlying mechanisms of the disease. 

    The overall Myasthenia Gravis Market data points to the necessity of specialized care and treatment based on specific disease types, hence driving market growth. The increased collaboration among stakeholders in the Myasthenia Gravis Market industry is expected to further enhance segment development and contribute positively to health outcomes for individuals affected by these conditions.

    Myasthenia Gravis Market Treatment Type Insights

    The Myasthenia Gravis Market revenue is strongly influenced by the Treatment Type segment, comprising various therapeutic strategies aimed at managing this neuromuscular disorder. As of 2024, this segment played a crucial role in the overall market, which is expected to reach 2.11 USD Billion. Within this segment, Anticholinesterase Agents are pivotal as they enhance neuromuscular transmission, significantly improving muscle strength in patients. Immunosuppressants follow closely, as they are vital in reducing autoimmune responses that contribute to the disease's progression.

    Additionally, Intravenous Immunoglobulin and Plasmapheresis are utilized for their efficacy in controlling acute exacerbations, showcasing their importance in providing rapid relief. Thymectomy is also noteworthy, particularly for patients with thymoma, as it can offer a potential cure by altering the disease's course. The growth in this segment is supported by rising awareness and improved diagnosis of Myasthenia Gravis globally, driving better access to these treatments. The Myasthenia Gravis Market data reveals that as the prevalence of the disorder grows, investments in Research and Development for these treatment modalities are also increasing, enhancing patient outcomes and overall market growth.

    Myasthenia Gravis Market Route of Administration Insights

    The Myasthenia Gravis Market, particularly focusing on the Route of Administration segment, is an important area within the healthcare industry. In 2024, the market was valued at 2.11 billion USD, reflecting significant growth opportunities driven by increasing prevalence rates of Myasthenia Gravis globally. The Route of Administration consists of various methods, with Oral, Intravenous, and Subcutaneous administration types being key components. Oral administration is favored for its ease of use and patient compliance, making it a prevalent option for many therapies.

    Intravenous administration, on the other hand, is effective for delivering rapid therapeutic effects, especially during acute exacerbations of Myasthenia Gravis. Meanwhile, Subcutaneous administration is gaining traction due to its convenience and ability to promote self-administration by patients, further enhancing treatment adherence. 

    Overall, the Myasthenia Gravis Market segmentation reflects diverse treatment options tailored to the needs of patients, contributing to an overall market growth trend, as evidenced by the expected valuation of 4.5 billion USD by 2035.This growth is driven by innovations in pharmaceutical development and the increasing demand for targeted therapies, which are crucial for improving the quality of life for those affected by this neuromuscular disorder.

    Myasthenia Gravis Market End User Insights

    The Myasthenia Gravis Market is showing significant growth, particularly in the End User segment where hospitals, specialty clinics, and homecare settings play vital roles. In 2024, the market was valued at 2.11 billion USD. Hospitals are essential as they provide comprehensive care for patients suffering from Myasthenia Gravis, including diagnosis, treatment, and ongoing management of this chronic neurological disease. Specialty clinics, focusing specifically on neuromuscular disorders, have become increasingly important, offering tailored treatment plans and advanced therapies.

    Homecare settings are emerging as a significant alternative for patients seeking comfort and personalized care at home, which supports their daily living needs and enhances their quality of life. The market is also witnessing a rise in telemedicine and remote monitoring solutions, further boosting patient engagement and care effectiveness. 

    Overall, the combination of these End Users forms a dynamic ecosystem crucial for effective management and treatment of Myasthenia Gravis, reflecting broader trends towards integrated care and patient-centered approaches in the healthcare industry.

    Get more detailed insights about Myasthenia Gravis Market Research Report – Global Forecast till 2035

    Regional Insights

    The Myasthenia Gravis Market is projected to witness significant growth across various regions, with North America holding the majority share, valued at 0.9 USD Billion in 2024 and expected to reach 1.8 USD Billion by 2035. This dominant position is driven by the advanced healthcare infrastructure and increasing awareness regarding Myasthenia Gravis treatments. 

    Europe follows closely, valued at 0.65 USD Billion in 2024 and anticipated to grow to 1.4 USD Billion by 2035, indicating robust healthcare systems and investment in Research and Development.The APAC region, with a market value of 0.4 USD Billion in 2024 and 1.0 USD Billion by 2035, is emerging as a significant player due to rising healthcare expenditures and an increasing patient population. Meanwhile, South America and the Middle East and Africa have smaller market shares, valued at 0.1 USD Billion and 0.06 USD Billion in 2024, respectively. 

    These regions represent opportunities for growth as healthcare access improves. Overall, the Myasthenia Gravis Market revenue is likely to rise significantly, influenced by various factors, including government initiatives aiming to enhance healthcare systems and therapeutic advancements in the treatment of this autoimmune disorder..

    Myasthenia Gravis Market Region

    Key Players and Competitive Insights

    The Myasthenia Gravis Market has been witnessing significant developments driven by the increasing prevalence of the disease, alongside rising awareness about treatment options and ongoing research initiatives. Myasthenia gravis is a chronic autoimmune neuromuscular disorder that results in varying degrees of skeletal muscle weakness, creating a robust demand for effective therapies. The competitive landscape in this market reveals a mix of established pharmaceutical companies and emerging biotech firms, each striving to innovate in their offerings to meet the diverse needs of patients.

    The competition encourages investments in research and development, leading to the introduction of novel therapeutic agents and treatment protocols, which further enrich the treatment landscape and provide patients with better outcomes.Pfizer has established a notable presence in the Myasthenia Gravis Market through its comprehensive approach in addressing the needs of patients suffering from this condition. The company's strength lies in its well-diversified portfolio of neuromuscular disorder therapies, which enhances its ability to penetrate this market. 

    Pfizer has engaged in strategic partnerships and collaborations aimed at advancing research and improving patient access to therapies. Furthermore, its strong commitment to clinical trials and post-market studies positions it as a trusted entity in the field, ensuring that the therapeutic options offered are both safe and effective. As Pfizer continues to develop and refine its product offerings, it strengthens its foothold in the competitive landscape of the Myasthenia Gravis Market, leveraging its robust global distribution channels and marketing expertise to reach a wide array of healthcare providers and patients.

    Merck and Co has also made significant strides in the Myasthenia Gravis Market, showcasing its commitment through a range of approved therapeutic options and ongoing research endeavors. Merck is recognized for its innovative approaches to treatment, particularly focusing on the development of monoclonal antibodies and immunotherapies that address the underlying mechanisms of myasthenia gravis. The company’s active pursuit of mergers and acquisitions in the pharmaceutical sector has further bolstered its capabilities, allowing it to expand its research pipeline and enhance its product offerings. 

    Notably, Merck's emphasis on patient-centric solutions and community engagement has solidified its market presence, establishing strong relationships with healthcare providers and advocacy groups. The combination of Merck's high-quality products and its strategic initiatives effectively positions the company as a key player in the Myasthenia Gravis Market, providing hope to patients and families affected by this challenging condition.

    Key Companies in the Myasthenia Gravis Market market include

    Industry Developments

    • Q4 2024: UCB receives FDA approval for ZILBRYSQ (zilucoplan) for generalized myasthenia gravis in adults UCB announced that the U.S. FDA approved ZILBRYSQ (zilucoplan), a once-daily subcutaneous peptide inhibitor, for the treatment of generalized myasthenia gravis in adult patients, marking a significant regulatory milestone for the company.
    • Q2 2024: Argenx receives European Commission approval for Vyvgart for generalized myasthenia gravis Argenx secured European Commission approval for its drug Vyvgart (efgartigimod alfa) for the treatment of generalized myasthenia gravis, expanding its market presence in Europe.
    • Q1 2024: Alexion, AstraZeneca Rare Disease, announces positive Phase 3 results for Ultomiris in myasthenia gravis Alexion, AstraZeneca Rare Disease, reported positive Phase 3 clinical trial results for Ultomiris (ravulizumab) in patients with generalized myasthenia gravis, paving the way for potential regulatory submissions.
    • Q2 2024: UCB partners with Roche to co-develop new monoclonal antibody for myasthenia gravis UCB and Roche announced a strategic partnership to co-develop a next-generation monoclonal antibody targeting refractory myasthenia gravis, aiming to address unmet clinical needs.
    • Q3 2024: Argenx raises $400 million in public offering to expand myasthenia gravis drug portfolio Argenx completed a $400 million public offering to support the expansion of its myasthenia gravis drug portfolio and fund ongoing clinical trials.
    • Q2 2025: Descartes-08 receives FDA Fast Track designation for myasthenia gravis Descartes-08, a novel RNA-engineered cell therapy, was granted Fast Track designation by the FDA for the treatment of generalized myasthenia gravis, accelerating its development timeline.
    • Q1 2025: AstraZeneca opens new manufacturing facility for myasthenia gravis biologics in the US AstraZeneca inaugurated a new state-of-the-art manufacturing facility in the United States dedicated to producing biologics for rare diseases, including myasthenia gravis.
    • Q2 2024: Immunovant announces $230 million Series C funding to advance anti-FcRn antibody for myasthenia gravis Immunovant raised $230 million in Series C funding to accelerate the development of its anti-FcRn antibody, IMVT-1402, for the treatment of myasthenia gravis.
    • Q3 2024: Janssen submits BLA to FDA for nipocalimab in generalized myasthenia gravis Janssen, a Johnson & Johnson company, submitted a Biologics License Application (BLA) to the FDA for nipocalimab, a monoclonal antibody for the treatment of generalized myasthenia gravis.
    • Q2 2025: Telitacicept receives conditional approval in China for myasthenia gravis Telitacicept, developed by RemeGen, received conditional approval from Chinese regulators for the treatment of myasthenia gravis, marking its first market entry.
    • Q1 2025: UCB appoints new Head of Rare Disease Division to lead myasthenia gravis strategy UCB announced the appointment of a new Head of Rare Disease Division to oversee its global strategy for myasthenia gravis and other rare autoimmune disorders.
    • Q4 2024: CRD-1 initiates Phase 2 trial for seronegative myasthenia gravis patients CRD-1, a novel therapeutic candidate, began Phase 2 clinical trials targeting seronegative myasthenia gravis patients, addressing a significant unmet need in the market.

    Future Outlook

    Myasthenia Gravis Market Future Outlook

    The Global Myasthenia Gravis Market is projected to grow at a 7.13% CAGR from 2024 to 2035, driven by advancements in therapeutics, increased awareness, and improved diagnostic technologies.

    New opportunities lie in:

    • Invest in novel biologics targeting specific autoimmune pathways.
    • Develop digital health solutions for remote patient monitoring and management.
    • Expand clinical trial networks to accelerate drug development timelines.

    By 2035, the Myasthenia Gravis Market is expected to exhibit robust growth, reflecting advancements in treatment and patient care.

    Market Segmentation

    Myasthenia Gravis Market End User Outlook

    • Hospitals
    • Specialty Clinics
    • Homecare Settings

    Myasthenia Gravis Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Myasthenia Gravis Market Disease Type Outlook

    • Acetylcholine Receptor Antibody Positive Myasthenia Gravis
    • Muscle-Specific Kinase Antibody Positive Myasthenia Gravis
    • Seronegative Myasthenia Gravis

    Myasthenia Gravis Market Treatment Type Outlook

    • Anticholinesterase Agents
    • Immunosuppressants
    • Intravenous Immunoglobulin
    • Plasmapheresis
    • Thymectomy

    Myasthenia Gravis Market Route of Administration Outlook

    • Oral
    • Intravenous
    • Subcutaneous

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2023 1.97(USD Billion)
    MARKET SIZE 2024 2.11(USD Billion)
    MARKET SIZE 2035 4.5(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 7.11% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2023
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED Pfizer, Merck and Co, Grifols, Roche, Johnson and Johnson, UCB, Teva Pharmaceutical Industries, Eisai, Novartis, Mylan, BristolMyers Squibb, AstraZeneca, Alexion Pharmaceuticals, Amgen, Sanofi
    SEGMENTS COVERED Disease Type, Treatment Type, Route of Administration, End User, Regional
    KEY MARKET OPPORTUNITIES Biologics and biosimilars development, Novel therapeutic approaches emerging, Increased genetic research initiatives, Expanding patient support programs, Telehealth and remote monitoring solutions
    KEY MARKET DYNAMICS increasing prevalence of autoimmune diseases, growing pharmaceutical investments, advancements in treatment options, rising awareness and diagnosis, strong pipeline of therapies
    COUNTRIES COVERED North America, Europe, APAC, South America, MEA

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the total expected value of the Global Myasthenia Gravis Market in 2024?

    The Global Myasthenia Gravis Market is expected to be valued at 2.11 USD Billion in 2024.

    What is the projected market value for the Global Myasthenia Gravis Market by 2035?

    The market is projected to reach a value of 4.5 USD Billion by 2035.

    What is the expected CAGR for the Global Myasthenia Gravis Market from 2025 to 2035?

    The expected CAGR for the market from 2025 to 2035 is 7.11%.

    Which region holds the largest market share in the Global Myasthenia Gravis Market in 2024?

    North America holds the largest market share with a value of 0.9 USD Billion in 2024.

    What is the estimated market value for Europe in the Global Myasthenia Gravis Market by 2035?

    The estimated market value for Europe is projected to be 1.4 USD Billion by 2035.

    What market size is anticipated for Acetylcholine Receptor Antibody Positive Myasthenia Gravis in 2024?

    The market size for Acetylcholine Receptor Antibody Positive Myasthenia Gravis is expected to be 0.87 USD Billion in 2024.

    Who are the key players in the Global Myasthenia Gravis Market?

    Key players include Pfizer, Merck & Co, Roche, Johnson & Johnson, and UCB among others.

    What is the market value for Muscle-Specific Kinase Antibody Positive Myasthenia Gravis in 2035?

    The market value for Muscle-Specific Kinase Antibody Positive Myasthenia Gravis is projected to be 1.43 USD Billion in 2035.

    What challenges impact the Global Myasthenia Gravis Market growth?

    Challenges include rising healthcare costs and limited awareness of the disease which may affect growth.

    What is the expected market size for Seronegative Myasthenia Gravis by 2035?

    The expected market size for Seronegative Myasthenia Gravis is projected to be 1.22 USD Billion by 2035.

    Myasthenia Gravis Market Research Report – Global Forecast till 2035 Infographic
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