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    Plasma Protein Therapeutic Market

    ID: MRFR/HC/41568-HCR
    200 Pages
    Garvit Vyas
    October 2025

    Plasma Protein Therapeutic Market Research Report By Application (Immunology, Hematology, Neurology, Oncology), By Product Type (Intravenous Immunoglobulin, Coagulation Factor Concentrates, Albumin, Alpha-1 Antitrypsin), By End Use (Hospitals, Homecare Settings, Ambulatory Surgical Centers), By Patient Type (Pediatric, Adult, Geriatric) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa)- Forecast to 2035

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    Plasma Protein Therapeutic Market Summary

    The Global Plasma Protein Therapeutic Market is projected to grow from 28.7 USD Billion in 2024 to 45 USD Billion by 2035, reflecting a steady increase in demand.

    Key Market Trends & Highlights

    Plasma Protein Therapeutic Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 4.17 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 45 USD Billion, indicating robust growth potential.
    • In 2024, the market is valued at 28.7 USD Billion, showcasing a solid foundation for future expansion.
    • Growing adoption of plasma protein therapies due to increasing prevalence of chronic diseases is a major market driver.

    Market Size & Forecast

    2024 Market Size 28.7 (USD Billion)
    2035 Market Size 45 (USD Billion)
    CAGR (2025-2035) 4.17%

    Major Players

    Innovative Bioresearch, ADMA Biologics, Baxalta, Medicago, Grifols, Fresenius Kabi, LFBBlood Centers of America, CSL Behring, Biotest, Sanjivani, Takeda Pharmaceutical, Octapharma, HemaCare, Kedrion

    Plasma Protein Therapeutic Market Trends

    The Global Plasma Protein Therapeutic Market is driven by an increasing prevalence of chronic diseases and immune disorders requiring regular treatment. Advances in technology have led to more efficient and safer production methods for plasma-derived products, enhancing their availability. The growing awareness and acceptance of these therapies among patients and healthcare providers contribute significantly to market growth. Additionally, the rise in healthcare spending across various regions supports the market, as governments and institutions invest more in treating conditions with plasma protein therapies, further fueling demand.

    There are numerous opportunities to be explored in this market, particularly in the area of research and development.

    Innovations in product formulations and the development of new therapies for currently untreatable conditions can open new avenues for companies. Increased collaboration between pharmaceutical companies and research institutions can accelerate the introduction of novel therapies, leading to enhanced treatment options. Moreover, expanding into emerging markets presents significant growth potential, given the rising incidences of diseases and the increasing population that requires therapeutic interventions. Recent trends show a greater focus on personalized medicine, where treatments are tailored to individual patients based on genetic makeup or specific disease characteristics.

    The rise in demand for immunoglobulins for autoimmune diseases and the steady increase in the usage of clotting factor concentrates in hemophilia patients further highlight evolving preferences in treatment strategies. Regulatory bodies continue to enhance guidelines for the approval of new therapies, pushing companies to invest more in compliance and standardized production processes. Overall, the combination of these dynamics illustrates a robust landscape with ongoing developments in the realm of plasma protein therapeutics.

    The Global Plasma Protein Therapeutic Market appears to be experiencing robust growth, driven by increasing demand for immunoglobulin therapies and advancements in manufacturing technologies.

    U.S. Food and Drug Administration (FDA)

    Plasma Protein Therapeutic Market Drivers

    Advancements in Biotechnology

    Technological advancements in biotechnology are propelling the Global Plasma Protein Therapeutic Market Industry forward. Innovations in protein engineering and purification techniques enhance the efficacy and safety of plasma-derived therapies. For example, the development of recombinant factor VIII products has improved treatment outcomes for hemophilia patients. These advancements not only increase the therapeutic options available but also expand the market's reach. As a result, the industry is poised for growth, with projections indicating a market size of 45 USD Billion by 2035, reflecting a robust CAGR of 4.17% from 2025 to 2035.

    Market Trends and Projections

    The Global Plasma Protein Therapeutic Market Industry is characterized by several key trends and projections. As of 2024, the market is valued at 28.7 USD Billion, with expectations to reach 45 USD Billion by 2035. The projected compound annual growth rate (CAGR) of 4.17% from 2025 to 2035 indicates a steady expansion of the industry. Factors such as rising demand for immunoglobulin therapies, advancements in manufacturing processes, and increasing patient populations are contributing to this growth trajectory. These trends underscore the dynamic nature of the market and its potential for future development.

    Rising Prevalence of Chronic Diseases

    The Global Plasma Protein Therapeutic Market Industry is experiencing growth driven by the increasing prevalence of chronic diseases such as hemophilia, immunodeficiencies, and liver disorders. As the global population ages, the incidence of these conditions is likely to rise, necessitating advanced therapeutic solutions. For instance, hemophilia affects approximately 1 in 5,000 male births, leading to a significant demand for plasma-derived therapies. This trend is expected to contribute to the market's valuation, projected to reach 28.7 USD Billion in 2024, as healthcare systems adapt to the growing need for effective treatments.

    Growing Awareness and Diagnosis of Rare Diseases

    The Global Plasma Protein Therapeutic Market Industry benefits from heightened awareness and improved diagnostic capabilities for rare diseases. As healthcare professionals become more adept at identifying conditions that require plasma-derived therapies, the demand for these products is expected to rise. Initiatives aimed at educating both healthcare providers and patients about rare diseases are fostering earlier diagnoses and treatment interventions. This trend is particularly relevant for conditions like primary immunodeficiency disorders, which often go undiagnosed for years. Consequently, the market is likely to see increased utilization of plasma therapies, further driving growth.

    Increased Investment in Research and Development

    Investment in research and development is a crucial driver for the Global Plasma Protein Therapeutic Market Industry. Pharmaceutical companies are allocating substantial resources to discover and develop new therapies that utilize plasma proteins. This focus on innovation is evident in the increasing number of clinical trials aimed at exploring novel applications of plasma-derived products. For instance, the development of immunoglobulin therapies for autoimmune diseases is gaining traction. Such investments are likely to enhance the therapeutic landscape, thereby contributing to the market's anticipated growth trajectory.

    Regulatory Support and Streamlined Approval Processes

    Regulatory support plays a pivotal role in shaping the Global Plasma Protein Therapeutic Market Industry. Governments and regulatory bodies are increasingly recognizing the importance of plasma-derived therapies, leading to streamlined approval processes for new products. Initiatives aimed at expediting the review of innovative therapies are fostering a conducive environment for market growth. For example, the introduction of fast-track designations for certain plasma products has accelerated their availability to patients. This supportive regulatory landscape is likely to enhance the market's expansion, facilitating access to life-saving therapies.

    Market Segment Insights

    Plasma Protein Therapeutic Market Application Insights

    The Global Plasma Protein Therapeutic Market, particularly within the Application segment, demonstrates a vast potential for growth and diversification. As of 2024, the overall market is projected to be valued at approximately 28.7 USD Billion, with a steady increase expected as the industry adapts to evolving healthcare needs. One of the most significant segments in Immunology, valued at 8.5 USD Billion in 2024 and is anticipated to grow to 13.5 USD Billion by 2035, indicating its crucial role in addressing autoimmune disorders and inflammatory diseases, especially as advancements in immunotherapies gain traction.

    Following closely is the Hematology segment, valued at 7.0 USD Billion in 2024 and expected to rise to 11.0 USD Billion by 2035, highlighting the essential function of plasma proteins in treating blood-related disorders, such as hemophilia, thereby illustrating the segment's importance to patient care and management. The Neurology application, holding a valuation of 6.0 USD Billion in 2024, is projected to increase to 9.0 USD Billion by 2035, underlining the critical need for plasma-derived therapies in rare neurological conditions and showcasing how innovations in this area can significantly improve patient outcomes.

    The Oncology segment, valued at 7.2 USD Billion in 2024 and projected to grow to 11.5 USD Billion by 2035, highlights the applicability of plasma protein therapies in cancer treatment, particularly as supportive care options in combating treatment-associated deficiencies and improving overall patient well-being. Each of these segments contributes uniquely to the overall Global Plasma Protein Therapeutic Market revenue, with Immunology and Hematology significantly dominating and reflecting a robust market response to chronic and critical therapeutic needs.

    The growth drivers across these applications stem from a rise in chronic diseases, advancements in therapeutic innovation, and increased adoption of personalized medicine. Mixed with the challenges of regulatory approvals and high treatment costs, these segments present a unique landscape filled with both significant opportunities and hurdles, which are essential for stakeholders navigating the Global Plasma Protein Therapeutic Market industry. Emphasizing the role of these applications not only illustrates the market's statistical growth but also emphasizes the necessity for continued research, development, and investment in plasma protein therapies to meet existing and emergent healthcare demands effectively.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Plasma Protein Therapeutic Market Product Type Insights

    The Global Plasma Protein Therapeutic Market is experiencing steady growth; within this market, the Product Type segment plays a crucial role, encompassing various essential products such as Intravenous Immunoglobulin, Coagulation Factor Concentrates, Albumin and Alpha-1 Antitrypsin. Intravenous Immunoglobulin is noteworthy for its significant application in treating immunodeficiency disorders, effectively influencing market dynamics. Coagulation Factor Concentrates are pivotal for hemophilia management, reflecting a substantial demand driven by rising patient populations and awareness.

    Albumin, known for its vital role in maintaining oncotic pressure, also holds importance in therapeutic interventions, leading to a considerable market share. Meanwhile, Alpha-1 Antitrypsin serves as a critical treatment for lung diseases, further emphasizing its significance in patient care. The overall landscape of the Global Plasma Protein Therapeutic Market segmentation indicates a variety of opportunities, driven by increasing chronic diseases and advancements in treatment regimens, positioning the market for continuous growth as healthcare providers increasingly rely on these plasma-derived therapies.

    Plasma Protein Therapeutic Market End Use Insights

    The Global Plasma Protein Therapeutic Market has been witnessing steady growth with its end-use segmentation playing a crucial role in shaping market dynamics. Hospitals aresignificant user of these therapies, emphasizing their importance in patient care and treatment efficacy, as they hold a majority while catering to a broad range of treatment options. Homecare settings are gaining traction, driven by the shift towards patient-centric care and the growing preference for convenient treatment options that enable patients to receive therapy in their own homes.

    Ambulatory surgical centers also contribute significantly to the market growth, providing specialized care while minimizing hospital stays. With advancements in treatment protocols and an increasing prevalence of chronic diseases, the Global Plasma Protein Therapeutic Market is positioned for continued expansion. The market growth is supported by factors such as rising awareness about plasma therapies, an increase in product approvals, and ongoing research aimed at developing innovative treatments to meet patient needs.

    However, challenges such as regulatory hurdles and the high costs of therapies remain.Overall, the Global Plasma Protein Therapeutic Market data reflects a robust landscape that continues to evolve alongside advancements in medical technology and patient care paradigms.

    Plasma Protein Therapeutic Market Patient Type Insights

    The market statistics indicate a diverse spectrum of needs, where the Adult segment often shows a majority holding, reflecting the higher prevalence of disorders treated with plasma protein therapies in this demographic. Pediatric patients, while fewer in number, represent a crucial growth opportunity due to the need for specialized treatment options tailored to younger populations.

    Geriatric patients are increasingly significant as the global aging population grows, leading to a rise in age-related diseases that require plasma-derived therapies. The market growth is driven by an increasing incidence of immunodeficiencies and other chronic conditions across these patient types, alongside innovations in manufacturing and distribution that enhance access to therapies. Challenges include regulatory hurdles and varying reimbursement policies across regions, but opportunities remain in developing therapies for niche populations within these segments.

    Overall, the Global Plasma Protein Therapeutic Market segmentation highlights the importance of addressing the unique needs of different patient demographics to foster growth and improve patient outcomes.

    Get more detailed insights about Plasma Protein Therapeutic Market Research Report-Forecast Till 2035

    Regional Insights

    The Global Plasma Protein Therapeutic Market is projected to experience diverse growth across its regional segments. In 2024, North America is expected to hold a majority share, valued at 12.1 USD Billion, and will rise to 18.5 USD Billion by 2035, driven by advanced healthcare infrastructure and increased prevalence of plasma-related conditions. Europe follows with a valuation of 8.3 USD Billion in 2024, reaching 13.0 USD Billion in 2035, benefiting from robust regulatory support for plasma therapies.

    The APAC region, valued at 5.4 USD Billion in 2024 and anticipated to grow to 8.5 USD Billion by 2035, shows significant potential due to rising healthcare demands and increased awareness about therapeutics.

    South America and MEA, while currently smaller markets are expected to expand from 1.5 USD Billion to 2.3 USD Billion and from 1.4 USD Billion to 2.7 USD Billion, respectively, reflecting growing healthcare investments and improving access to treatments. Overall, the Global Plasma Protein Therapeutic Market data highlights a landscape where North America leads significantly, demonstrating the importance of this region in setting the trend and fostering innovation within the industry.

    Plasma Protein Therapeutic Market Region

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Global Plasma Protein Therapeutic Market has witnessed significant growth and diversity in recent years due to an increasing focus on advanced therapies and therapies derived from human plasma. This market comprises a range of products aimed at diseases such as hemophilia, immunodeficiencies, and neurological disorders, with plasma-derived therapies being pivotal for patient care. The competitive landscape is characterized by several key players who have established a robust foothold in the industry, leveraging their technological advances, extensive distribution networks, and strategic collaborations to meet the evolving needs of healthcare providers and patients alike.

    As the demand for these therapies escalates, companies are increasingly focusing on innovation, regulatory compliance, and operational excellence to enhance their market positioning and capitalize on emerging opportunities within this dynamic environment.

    Innovative Bioresearch has emerged as a notable contender within the Global Plasma Protein Therapeutic Market, recognized for its commitment to quality and patient-centered solutions. The company is distinguished by its advanced research capabilities and innovative manufacturing processes, which contribute to the development of high-quality plasma-derived therapeutics. These strengths are reflected in their ability to address unmet medical needs with a portfolio that emphasizes efficacy and safety. Additionally, Innovative Bioresearch is known for its strategic partnerships with healthcare providers and academic institutions to accelerate product development and improve access to treatments. 

    This collaborative approach enhances their market presence and solidifies their reputation as a leader in the domain of plasma protein therapeutics. Their focus on customization and responsiveness to market demands positions them favorably against competitors.ADMA Biologics stands out in the Global Plasma Protein Therapeutic Market, particularly for its specialized focus on immunoglobulin-based therapies. The company is recognized for its extensive product pipeline and dedication to addressing the needs of patients with immunodeficiency disorders.

    ADMA Biologics has invested significantly in its state-of-the-art manufacturing facilities, which adhere to the highest standards of quality control and regulatory compliance, ensuring that their products meet industry benchmarks. 

    Their ability to produce high-purity immunoglobulin products has fostered a high degree of trust among healthcare professionals and patients. Furthermore, ADMA Biologics is strategically pursuing opportunities for growth through product differentiation and acquisitions, allowing them to expand their market share effectively. Their unique positioning within the market, along with a customer-centric approach, further underlines their potential to thrive amidst competition in the Global Plasma Protein Therapeutic Market.

    Key Companies in the Plasma Protein Therapeutic Market market include

    Industry Developments

    • Q2 2024: Takeda Opens New Plasma-Derived Therapies Manufacturing Facility in Japan Takeda announced the opening of a new manufacturing facility in Osaka, Japan, dedicated to the production of plasma-derived therapies, aiming to increase supply capacity and meet growing demand for plasma protein therapeutics.
    • Q2 2024: Grifols Receives FDA Approval for New Plasma Fractionation Plant in North Carolina Grifols received approval from the U.S. FDA to begin operations at its new plasma fractionation facility in Clayton, North Carolina, expanding its production capabilities for plasma protein therapeutics.
    • Q2 2024: CSL Behring Announces Launch of New Immunoglobulin Therapy in Europe CSL Behring launched a new intravenous immunoglobulin (IVIG) therapy in several European countries, expanding its plasma protein therapeutics portfolio for the treatment of immune deficiencies.
    • Q3 2024: Kedrion and Kamada Announce Strategic Partnership to Develop Plasma-Derived Therapies Kedrion and Kamada entered into a strategic partnership to co-develop and commercialize new plasma-derived protein therapeutics, focusing on rare and orphan diseases.
    • Q3 2024: Octapharma Opens New Plasma Collection Center in the United States Octapharma announced the opening of a new plasma collection center in Texas, USA, to support the growing need for plasma used in the production of plasma protein therapeutics.
    • Q4 2024: Biotest Receives European Commission Approval for New Albumin Product Biotest AG received approval from the European Commission for its new albumin product, expanding its plasma protein therapeutics offerings in the European market.
    • Q4 2024: Grifols Completes Acquisition of Plasma Collection Centers in Canada Grifols completed the acquisition of several plasma collection centers in Canada, strengthening its plasma sourcing network for the production of plasma protein therapeutics.
    • Q1 2025: CSL Behring Announces $200 Million Investment in New Plasma Fractionation Facility in Australia CSL Behring announced a $200 million investment to build a new plasma fractionation facility in Melbourne, Australia, to increase production capacity for plasma protein therapeutics.
    • Q1 2025: Takeda Receives FDA Approval for Expanded Use of Plasma-Derived Therapy for CIDP Takeda received U.S. FDA approval for the expanded use of its plasma-derived therapy for the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP).
    • Q2 2025: Kamada Announces FDA Approval of Plasma-Derived Alpha-1 Antitrypsin Therapy Kamada Ltd. received FDA approval for its plasma-derived alpha-1 antitrypsin therapy for the treatment of alpha-1 antitrypsin deficiency in the United States.
    • Q2 2025: Bio Products Laboratory Opens New Plasma Collection Center in Germany Bio Products Laboratory (BPL) opened a new plasma collection center in Germany to support the supply chain for plasma protein therapeutics.
    • Q2 2025: Octapharma Receives EMA Approval for New Intravenous Immunoglobulin Product Octapharma received approval from the European Medicines Agency (EMA) for its new intravenous immunoglobulin (IVIG) product, expanding its plasma protein therapeutics portfolio in Europe.

    Future Outlook

    Plasma Protein Therapeutic Market Future Outlook

    The Plasma Protein Therapeutic Market is projected to grow at a 4.17% CAGR from 2024 to 2035, driven by increasing demand for immunoglobulin therapies and advancements in manufacturing technologies.

    New opportunities lie in:

    • Invest in biosimilar development to enhance market share and reduce costs.
    • Leverage digital health technologies for patient engagement and adherence solutions.
    • Expand into emerging markets with tailored plasma therapies to meet local healthcare needs.

    By 2035, the Plasma Protein Therapeutic Market is expected to demonstrate robust growth and innovation, solidifying its critical role in global healthcare.

    Market Segmentation

    Patient Type Outlook

    • Pediatric
    • Adult
    • Geriatric

    Plasma Protein Therapeutic Market End Use Outlook

    • Hospitals
    • Homecare Settings
    • Ambulatory Surgical Centers

    Plasma Protein Therapeutic Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Plasma Protein Therapeutic Market Application Outlook

    • Immunology
    • Hematology
    • Neurology
    • Oncology

    Plasma Protein Therapeutic MarketPatient Type Outlook

    • Pediatric
    • Adult
    • Geriatric

    Plasma Protein Therapeutic Market Product Type Outlook

    • Intravenous Immunoglobulin
    • Coagulation Factor Concentrates
    • Albumin
    • Alpha-1 Antitrypsin

    Report Scope

    Scope:
    Attribute/Metric Source: Details
    MARKET SIZE 2023 27.55(USD Billion)
    MARKET SIZE 2024 28.7(USD Billion)
    MARKET SIZE 2035 45.0(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 4.17% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2023
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED Innovative Bioresearch, ADMA Biologics, Baxalta, Medicago, Grifols, Fresenius Kabi, LFB, Blood Centers of America, CSL Behring, Biotest, Sanjivani, Takeda Pharmaceutical, Octapharma, HemaCare, Kedrion
    SEGMENTS COVERED Application, Product Type, End Use, Patient Type, Regional
    KEY MARKET OPPORTUNITIES Increasing chronic disease prevalence, Advancements in manufacturing technologies, Rising demand for immunoglobulin therapies, Expanding applications in rare diseases, Growing awareness and patient advocacy
    KEY MARKET DYNAMICS Increasing prevalence of immunodeficiency disorders, Growing demand for targeted therapies, Rising investments in R&D, Stringent regulatory requirements, Expansion of distribution networks
    COUNTRIES COVERED North America, Europe, APAC, South America, MEA

    FAQs

    What is the projected market size of the Global Plasma Protein Therapeutic Market in 2024?

    The Global Plasma Protein Therapeutic Market is expected to be valued at 28.7 billion USD in 2024.

    What is the anticipated market value of the Global Plasma Protein Therapeutic Market by 2035?

    By 2035, the market is projected to reach a value of 45.0 billion USD.

    What is the expected compound annual growth rate (CAGR) for the market from 2025 to 2035?

    The expected CAGR for the Global Plasma Protein Therapeutic Market from 2025 to 2035 is 4.17%.

    Which region is expected to dominate the Global Plasma Protein Therapeutic Market by 2035?

    North America is expected to dominate the market, projected to reach 18.5 billion USD by 2035.

    What will be the market value for Immunology applications in the Global Plasma Protein Therapeutic Market in 2035?

    The market value for Immunology applications is anticipated to reach 13.5 billion USD by 2035.

    Which are the major players in the Global Plasma Protein Therapeutic Market?

    Key players include Innovative Bioresearch, ADMA Biologics, Baxalta, Grifols, and CSL Behring.

    What is the projected market size for the Hematology segment by 2035?

    The Hematology segment is expected to reach a market value of 11.0 billion USD by 2035.

    How much is the APAC region expected to grow in the Global Plasma Protein Therapeutic Market by 2035?

    The APAC region is projected to grow to 8.5 billion USD by 2035.

    What is the estimated market value for Neurology applications in 2024?

    The estimated market value for Neurology applications in 2024 is 6.0 billion USD.

    What will be the Oncology market value in 2035 within the Global Plasma Protein Therapeutic Market?

    The Oncology market value is anticipated to reach 11.5 billion USD by 2035.

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