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    Proliferative Diabetic Retinopathy Market

    ID: MRFR/HC/41691-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    Proliferative Diabetic Retinopathy Market Size, Growth Research Report By Treatment Type (Laser Therapy, Intravitreal Injections, Surgical Procedures, Photocoagulation, Anti-VEGF Therapy), By Diagnosis Type (Fundus Photography, Optical Coherence Tomography, Fluorescein Angiography, Ultrasound, Visual Field Testing), By End User (Hospitals, Ophthalmology Clinics, Research Institutes, Homecare, Ambulatory Surgical Centers), By Distribution Channel (Direct Tender, Retail Pharmacy, Online Pharmacy, Hospital Pharmacies, Specialty Clinics) and By ...

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    Proliferative Diabetic Retinopathy Market Infographic
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    Proliferative Diabetic Retinopathy Market Summary

    As per MRFR analysis, the Proliferative Diabetic Retinopathy Market Size was estimated at 5.824 USD Billion in 2024. The Proliferative Diabetic Retinopathy industry is projected to grow from 6.133 USD Billion in 2025 to 10.29 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 5.31 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The Proliferative Diabetic Retinopathy Market is experiencing dynamic growth driven by technological advancements and increasing awareness.

    • Advancements in treatment modalities are reshaping the therapeutic landscape, particularly in North America, which remains the largest market.
    • Increased awareness and education about diabetic retinopathy are contributing to higher diagnosis rates across the Asia-Pacific region, the fastest-growing market.
    • The Anti-VEGF therapy segment continues to dominate, while intravitreal injections are emerging as the fastest-growing treatment option.
    • Rising prevalence of diabetes and government initiatives are key drivers propelling market expansion, particularly in the context of novel therapeutics.

    Market Size & Forecast

    2024 Market Size 5.824 (USD Billion)
    2035 Market Size 10.29 (USD Billion)
    CAGR (2025 - 2035) 5.31%

    Major Players

    Regeneron Pharmaceuticals (US), Novartis (CH), Roche (CH), Bayer (DE), Pfizer (US), Eli Lilly and Company (US), AstraZeneca (GB), Santen Pharmaceutical (JP), Horizon Therapeutics (IE)

    Proliferative Diabetic Retinopathy Market Trends

    The Proliferative Diabetic Retinopathy Market is currently experiencing notable developments driven by advancements in treatment options and increasing awareness of diabetic eye diseases. As healthcare providers and patients alike become more informed about the implications of diabetic retinopathy, there appears to be a growing demand for effective therapies. This trend is further supported by ongoing research and innovation in medical technology, which seems to enhance the efficacy of existing treatments while introducing novel approaches. Additionally, the rising prevalence of diabetes globally contributes to a larger patient population requiring specialized care, thereby expanding the market's potential. Moreover, the Proliferative Diabetic Retinopathy Market is likely to benefit from collaborative efforts among pharmaceutical companies, healthcare institutions, and research organizations. These partnerships may facilitate the development of comprehensive treatment protocols and improve patient outcomes. Furthermore, the integration of telemedicine and digital health solutions into patient management strategies could enhance accessibility to care, particularly in underserved regions. As the market evolves, it is essential to monitor these dynamics closely, as they may shape the future landscape of diabetic retinopathy management and treatment options.

    Advancements in Treatment Modalities

    The Proliferative Diabetic Retinopathy Market is witnessing a surge in innovative treatment modalities. New therapies, including anti-VEGF injections and laser treatments, are being refined to improve patient outcomes. These advancements not only enhance the effectiveness of existing treatments but also provide patients with more options tailored to their specific needs.

    Increased Awareness and Education

    There is a growing emphasis on awareness and education regarding diabetic retinopathy. Healthcare providers are actively engaging in outreach programs to inform patients about the risks associated with diabetes and the importance of regular eye examinations. This heightened awareness is likely to lead to earlier diagnosis and treatment, positively impacting the market.

    Integration of Digital Health Solutions

    The integration of digital health solutions into the management of diabetic retinopathy is becoming increasingly prevalent. Telemedicine platforms and mobile health applications are facilitating remote monitoring and consultations, thereby improving access to care. This trend may enhance patient engagement and adherence to treatment regimens, ultimately benefiting the Proliferative Diabetic Retinopathy Market.

    The increasing prevalence of diabetes globally is likely to drive a corresponding rise in cases of proliferative diabetic retinopathy, necessitating enhanced screening and treatment strategies to mitigate vision loss.

    Centers for Disease Control and Prevention (CDC)

    Proliferative Diabetic Retinopathy Market Drivers

    Growing Geriatric Population

    The growing geriatric population is a significant driver for the Proliferative Diabetic Retinopathy Market. As individuals age, the risk of developing diabetes and its associated complications, including diabetic retinopathy, increases. By 2030, it is estimated that the number of people aged 60 and above will surpass 1.4 billion, creating a larger demographic susceptible to these conditions. This demographic shift necessitates enhanced healthcare services and treatment options tailored to older adults. Consequently, the Proliferative Diabetic Retinopathy Market is likely to expand as healthcare providers seek to address the unique needs of this population, ensuring timely diagnosis and effective management.

    Rising Prevalence of Diabetes

    The increasing prevalence of diabetes worldwide is a primary driver for the Proliferative Diabetic Retinopathy Market. According to recent estimates, the number of individuals diagnosed with diabetes is projected to reach 700 million by 2045. This surge in diabetes cases correlates with a heightened risk of developing diabetic retinopathy, particularly its proliferative form. As more patients require screening and treatment, the demand for innovative therapies and interventions in the Proliferative Diabetic Retinopathy Market is likely to escalate. Furthermore, the growing recognition of diabetes as a leading cause of blindness underscores the urgency for effective management strategies, thereby propelling market growth.

    Emergence of Novel Therapeutics

    The emergence of novel therapeutics is reshaping the Proliferative Diabetic Retinopathy Market. Recent developments in pharmacological treatments, such as anti-VEGF therapies and corticosteroids, have shown promise in managing the progression of diabetic retinopathy. These innovative therapies not only aim to halt disease progression but also improve visual outcomes for patients. The introduction of combination therapies and sustained-release drug delivery systems is further enhancing treatment efficacy. As research continues to unveil new therapeutic options, the Proliferative Diabetic Retinopathy Market is poised for growth, driven by the demand for more effective and patient-centric treatment solutions.

    Government Initiatives and Funding

    Government initiatives aimed at combating diabetes and its complications are playing a pivotal role in the Proliferative Diabetic Retinopathy Market. Various health organizations are implementing programs to raise awareness about diabetic retinopathy and promote regular eye examinations among diabetic patients. Additionally, increased funding for research and development of new treatment options is likely to enhance the market landscape. For instance, public health campaigns and subsidies for screening programs can lead to higher patient engagement and treatment adherence. Such initiatives not only improve patient outcomes but also stimulate growth within the Proliferative Diabetic Retinopathy Market.

    Technological Advancements in Diagnostics

    Technological advancements in diagnostic tools are significantly influencing the Proliferative Diabetic Retinopathy Market. Innovations such as optical coherence tomography (OCT) and fundus photography have enhanced the ability to detect and monitor the progression of diabetic retinopathy. These technologies facilitate early diagnosis, which is crucial for effective treatment and management. The integration of artificial intelligence in imaging analysis is also emerging, potentially improving diagnostic accuracy and efficiency. As healthcare providers increasingly adopt these advanced diagnostic modalities, the Proliferative Diabetic Retinopathy Market is expected to experience substantial growth, driven by the need for timely and precise interventions.

    Market Segment Insights

    Proliferative Diabetic Retinopathy Market Treatment Type Insights

    The Proliferative Diabetic Retinopathy Market, focusing on Treatment Type, showcases a robust landscape due to the increasing prevalence of diabetic retinopathy and the growing demand for effective interventions. This market is poised to be valued at 5.83 USD Billion in 2024 and projected to reach 10.3 USD Billion by 2035, reflecting a steady growth trajectory. Analyzing the treatment avenues reveals that Laser Therapy stands out with a notable market evaluation of 1.1 USD Billion in 2024, expected to grow to 2.0 USD Billion by 2035.

    This segment has significant importance, given its critical role in halting or slowing down vision loss by targeting damaged blood vessels, thereby dominating the market share.Furthermore, Intravitreal Injections is another key player within the treatment landscape, valued at 2.0 USD Billion in 2024 and anticipated to rise to 3.5 USD Billion in 2035, showcasing its strong position.

    These injections deliver medication directly into the vitreous and are vital in managing inflammation and complications associated with proliferative diabetic retinopathy, making this treatment both effective and critical in patient management. Surgical Procedures also contribute to the market's viability with a valuation of 1.2 USD Billion in 2024, moving up to 2.2 USD Billion in 2035, indicating its essential nature in treating advanced stages of the disease by addressing retinal detachments or severe vitreous hemorrhage.

    Photocoagulation, with a pegged market value of 0.95 USD Billion in 2024, is expected to reach 1.7 USD Billion by 2035, reaffirming its role in precise tissue ablation to improve patient vision. Meanwhile, Anti-VEGF Therapy is in a steadily growing position with its market assessment at 0.58 USD Billion in 2024 andanticipated at 0.9 USD Billion in 2035; this therapy is particularly significant as it counters the vascular effects of diabetic retinopathy by inhibiting growth factors associated with abnormal blood vessel formation.

    The growth patterns seen across these treatment methods indicate a healthcare focus on enhancing patient outcomes through targeted therapies, addressing the increasing burden of diabetic complications.Overall, these dynamics and respective market share insights underscore how various treatment types are crucial in shaping the framework of the Proliferative Diabetic Retinopathy Market revenue, reflecting an essential response to the complex needs of a rising patient population.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Proliferative Diabetic Retinopathy Market Diagnosis Type Insights

    This market comprises various diagnostic techniques essential for the timely and accurate identification of proliferative diabetic retinopathy. Among these, Fundus Photography and Optical Coherence Tomography are crucial due to their ability to provide detailed images of the retina, thus facilitating better clinical assessments.

    Fluorescein Angiography serves a vital role in visualizing blood flow in the retina identifying areas of leakage or ischemia.Ultrasound is also important for cases where other imaging techniques may be limited, while Visual Field Testing contributes valuable data regarding the extent of visual impairment.

    The increasing prevalence of diabetes worldwide and the emphasis on early diagnosis further propel the need for these diagnostic tools within the market. As healthcare providers seek efficient solutions for monitoring and treating diabetic retinopathy, the demand for these diagnostic methods is expected to rise significantly, reflecting ongoing trends in the Proliferative Diabetic Retinopathy Market revenue and industry development.

    Proliferative Diabetic Retinopathy Market End User Insights

    The Proliferative Diabetic Retinopathy Market has shown significant growth across various End User segments. Hospitals play a crucial role, often serving as the primary healthcare setting for patients requiring advanced treatment and monitoring. Ophthalmology Clinics are also significant as they specialize in eye-related ailments, providing targeted care for proliferative diabetic retinopathy. Research Institutes contribute to the market by driving innovation and clinical studies, enhancing treatment methodologies and understanding of the disease.

    Homecare is gaining prominence as more patients seek personalized care options in their own environments, catering to the growing demand for convenience and accessibility. Ambulatory Surgical Centers further support the market by facilitating outpatient procedures, which often cut down recovery time and increase patient throughput. Each of these segments contributes to the overall revenue of the Proliferative Diabetic Retinopathy Market, reflecting a multi-faceted approach to managing this condition, while continuous advancements in technology and treatment options present new opportunities for growth.

    Proliferative Diabetic Retinopathy Market Distribution Channel Insights

    The Proliferative Diabetic Retinopathy Market has experienced significant growth, particularly in its Distribution Channel segment, which plays a critical role in product accessibility and patient care. Among these channels, Hospital Pharmacies and Specialty Clinics are crucial due to their ability to provide specialized care and medications directly to patients suffering from this condition.

    Retail Pharmacies also occupy a significant space in the market, offering convenience and broad access to diabetic retinopathy treatments for everyday consumers.Furthermore, the rise of Online Pharmacies has introduced an added layer of convenience, making it easier for patients to acquire necessary medications from the comfort of their homes.

    The Direct Tender method remains influential, particularly in government and institutional healthcare settings, ensuring that large quantities of medications reach facilities efficiently. These distribution channels collectively shape the Proliferative Diabetic Retinopathy Market revenue and create a competitive landscape driven by evolving patient needs and technological advancements in medicine delivery.With the favorable trends in digital health and e-commerce, leveraging Online Pharmacies can enhance patient adherence to therapies and broaden market reach, presenting substantial opportunities for growth in this segment.

    Get more detailed insights about Proliferative Diabetic Retinopathy Market

    Regional Insights

    The Proliferative Diabetic Retinopathy Market exhibits significant regional variation, with North America leading in market share. In 2024, North America held a market value of 2.6 USD Billion, expected to grow to 4.65 USD Billion by 2035, reflecting its majority holding in the industry.

    Europe follows, with a market valuation of 1.4 USD Billion in 2024, projected to rise to 2.5 USD Billion by 2035, indicating its significant role in the market. The APAC region is valued at 1.2 USD Billion in 2024 and is anticipated to reach 2.15 USD Billion by 2035, marking it as an important growth area due to increasing diabetic populations.South America reported a market value of 0.4 USD Billion in 2024, growing to 0.75 USD Billion by 2035, while the MEA region, valued at 0.23 USD Billion in 2024, is expected to grow to 0.45 USD Billion by 2035.

    This growth across various regions is driven by increased awareness, advancements in healthcare infrastructure, and a rising prevalence of diabetes, highlighting opportunities for stakeholders in the Proliferative Diabetic Retinopathy Market growth. Market dynamics indicate that North America and Europe will continue to dominate due to higher healthcare expenditure and advanced treatment solutions available in these regions.

    Proliferative Diabetic Retinopathy Market Region

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Proliferative Diabetic Retinopathy Market is characterized by a highly competitive landscape driven by the rising prevalence of diabetic retinopathy among the global population. As healthcare providers increasingly focus on innovative treatment options, the demand for advanced therapeutics has surged. Companies are engaging in extensive research and development, aiming to enhance patient outcomes and expand their product portfolios.

    The competitive dynamics are influenced by multiple factors, including technological advancements, strategic collaborations, and the increasing understanding of the underlying pathophysiological mechanisms of the disease. As market players strive to capture a significant share, understanding the competitive landscape is paramount for stakeholders involved in the development and delivery of solutions for proliferative diabetic retinopathy.

    Amgen has established a notable presence in the Proliferative Diabetic Retinopathy Market through its robust development pipeline and a commitment to addressing unmet medical needs. The company's extensive research efforts in the field of ophthalmic diseases have led to the creation of advanced treatments aimed specifically at managing diabetic retinopathy complications. Amgen's strength lies in its established reputation for innovation and quality, backed by a team of experts committed to driving scientific breakthroughs.

    Additionally, the company's strategic partnerships and collaborations with research institutions bolster its position, allowing Amgen to leverage shared knowledge and accelerate the development of its therapeutic offerings. This commitment to scientific excellence, combined with a focus on patient-centric strategies and direct engagement with healthcare professionals, enhances Amgen's competitive edge in this therapeutic field.

    On the other hand, Horizon Therapeutics embodies a strong commitment to addressing the needs of patients suffering from proliferative diabetic retinopathy, marking its presence in the Proliferative Diabetic Retinopathy Market. The company's strengths are reflected in its dedicated focus on rare and serious diseases, translating to specialized treatments that resonate with the specific challenges posed by diabetic retinopathy.

    Horizon Therapeutics actively engages in clinical trials to ensure evidence-based therapies and continuously seeks to expand its portfolio with novel solutions that can provide meaningful benefits to patients. The company’s approach emphasizes collaboration, not only with healthcare professionals but also with patient advocacy groups, ensuring a comprehensive understanding of patient needs and preferences. This positions Horizon Therapeutics as a pivotal player in the market, where its innovative solutions are crucial for the effective management and treatment of proliferative diabetic retinopathy.

    Key Companies in the Proliferative Diabetic Retinopathy Market market include

    Industry Developments

    • Q1 2024: Regeneron Announces FDA Approval of EYLEA HD (aflibercept) Injection 8 mg for the Treatment of Diabetic Retinopathy Regeneron received FDA approval for EYLEA HD (aflibercept) 8 mg, expanding its use to include the treatment of diabetic retinopathy, including proliferative diabetic retinopathy.
    • Q2 2024: Roche receives European Commission approval for Vabysmo® (faricimab) for the treatment of diabetic retinopathy Roche announced that the European Commission approved Vabysmo® (faricimab) for the treatment of diabetic retinopathy, including proliferative forms, marking a significant regulatory milestone in Europe.
    • Q2 2024: Novartis launches Beovu® (brolucizumab) in Japan for diabetic retinopathy Novartis launched Beovu® (brolucizumab) in Japan for the treatment of diabetic retinopathy, including proliferative diabetic retinopathy, following regulatory approval.
    • Q2 2024: Bayer and Regeneron expand collaboration to develop new combination therapy for proliferative diabetic retinopathy Bayer and Regeneron announced an expanded partnership to co-develop a new combination therapy targeting proliferative diabetic retinopathy, aiming to improve patient outcomes.
    • Q3 2024: FDA grants Fast Track designation to Kodiak Sciences’ KSI-301 for treatment of proliferative diabetic retinopathy Kodiak Sciences received Fast Track designation from the FDA for its investigational therapy KSI-301, intended for the treatment of proliferative diabetic retinopathy.
    • Q3 2024: Ocuphire Pharma Announces Positive Topline Results from ZETA-1 Phase 2b Trial of APX3330 in Diabetic Retinopathy Ocuphire Pharma reported positive topline results from its ZETA-1 Phase 2b trial evaluating APX3330 in patients with diabetic retinopathy, including those with proliferative disease.
    • Q4 2024: Genentech Initiates Phase III Study of RGX-314 for Proliferative Diabetic Retinopathy Genentech announced the initiation of a Phase III clinical trial for RGX-314, a gene therapy candidate for the treatment of proliferative diabetic retinopathy.
    • Q4 2024: Alimera Sciences Announces Commercial Launch of ILUVIEN® for Proliferative Diabetic Retinopathy in the UK Alimera Sciences launched ILUVIEN® for the treatment of proliferative diabetic retinopathy in the United Kingdom following regulatory clearance.
    • Q1 2025: FDA Approves First Biosimilar to Aflibercept for Diabetic Retinopathy The FDA approved the first biosimilar to aflibercept for use in diabetic retinopathy, including proliferative forms, expanding treatment options for patients.
    • Q2 2025: Regeneron and Samsung Bioepis Announce Strategic Manufacturing Partnership for EYLEA® Biosimilar Regeneron and Samsung Bioepis entered a strategic partnership to manufacture a biosimilar version of EYLEA® for global markets, including indications for proliferative diabetic retinopathy.
    • Q2 2025: Kodiak Sciences Announces $100 Million Private Placement to Advance KSI-301 for Proliferative Diabetic Retinopathy Kodiak Sciences raised $100 million in a private placement to support the late-stage development of KSI-301 for proliferative diabetic retinopathy.
    • Q3 2025: EMA Recommends Approval of Faricimab for Proliferative Diabetic Retinopathy The EMA recommended approval of faricimab for the treatment of proliferative diabetic retinopathy, paving the way for expanded access in Europe.

    Future Outlook

    Proliferative Diabetic Retinopathy Market Future Outlook

    The Proliferative Diabetic Retinopathy Market is poised for growth at a 5.31% CAGR from 2024 to 2035, driven by advancements in treatment technologies and increasing prevalence of diabetes.

    New opportunities lie in:

    • Develop innovative retinal imaging technologies to enhance early diagnosis.
    • Expand telemedicine services for remote patient monitoring and consultations.
    • Invest in research for novel pharmacological therapies targeting diabetic retinopathy.

    By 2035, the market is expected to demonstrate robust growth, reflecting advancements in treatment and increased awareness.

    Market Segmentation

    Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Proliferative Diabetic Retinopathy Market End User Outlook

    • Hospitals
    • Ophthalmology Clinics
    • Research Institutes
    • Homecare
    • Ambulatory Surgical Centers

    Proliferative Diabetic Retinopathy Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Proliferative Diabetic Retinopathy Market Diagnosis Type Outlook

    • Fundus Photography
    • Optical Coherence Tomography
    • Fluorescein Angiography
    • Ultrasound
    • Visual Field Testing

    Proliferative Diabetic Retinopathy Market Treatment Type Outlook

    • Laser Therapy
    • Intravitreal Injections
    • Surgical Procedures
    • Photocoagulation
    • Anti-VEGF Therapy

    Proliferative Diabetic Retinopathy Market Distribution Channel Outlook

    • Direct Tender
    • Retail Pharmacy
    • Online Pharmacy
    • Hospital Pharmacies
    • Specialty Clinics

    Report Scope

    Attribute/Metric Source: Details
    MARKET SIZE 2023 5.53(USD Billion)
    MARKET SIZE 2024 5.83(USD Billion)
    MARKET SIZE 2035 10.3(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 5.31% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2023
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED Amgen, Horizon Therapeutics, Merck and Co, Pfizer, BristolMyers Squibb, Aerie Pharmaceuticals, Allergan, AbbVie, Eli Lilly and Company, Novartis, BioMarin Pharmaceutical, Apellis Pharmaceuticals, Santen Pharmaceutical, Roche, Regeneron Pharmaceuticals
    SEGMENTS COVERED Treatment Type, Diagnosis Type, End User, Distribution Channel, Regional
    KEY MARKET OPPORTUNITIES Growing prevalence of diabetes, Advancements in treatment technologies, Increase in telemedicine adoption, Rising geriatric population, Expanding patient awareness programs
    KEY MARKET DYNAMICS Rising diabetes prevalence, Advancements in treatment technologies, Increasing healthcare expenditures, Growing awareness programs, Favorable reimbursement policies
    COUNTRIES COVERED North America, Europe, APAC, South America, MEA

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    FAQs

    What is the projected market size of the Global Proliferative Diabetic Retinopathy Market in 2024?

    The Global Proliferative Diabetic Retinopathy Market is expected to be valued at 5.83 USD Billion in 2024.

    What will be the market size of the Global Proliferative Diabetic Retinopathy Market by 2035?

    By 2035, the market is expected to reach a value of 10.3 USD Billion.

    What is the expected CAGR for the Global Proliferative Diabetic Retinopathy Market from 2025 to 2035?

    The expected CAGR for the market from 2025 to 2035 is 5.31%.

    Which region is anticipated to have the largest market share in 2024?

    North America is anticipated to have the largest market share, valued at 2.6 USD Billion in 2024.

    What will be the market value for European Proliferative Diabetic Retinopathy in 2035?

    The market value for Europe is projected to reach 2.5 USD Billion by 2035.

    How much revenue will Intravitreal Injections generate in 2024?

    Intravitreal Injections are expected to generate revenue of 2.0 USD Billion in 2024.

    What is the growth forecast for Surgical Procedures by 2035?

    Surgical Procedures are projected to grow to a market value of 2.2 USD Billion by 2035.

    Who are the key players in the Global Proliferative Diabetic Retinopathy Market?

    Key players in the market include Amgen, Merck & Co, Pfizer, and Novartis.

    What is the anticipated market value of Anti-VEGF Therapy in 2024?

    The anticipated market value of Anti-VEGF Therapy in 2024 is 0.58 USD Billion.

    How much is the total market for the Asia-Pacific region expected to be in 2035?

    The total market for the Asia-Pacific region is expected to reach 2.15 USD Billion by 2035.

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