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    Protein Engineering Market

    ID: MRFR/HC/0220-CR
    132 Pages
    Kinjoll Dey
    September 2021

    Protein Engineering Market Research Report Information By Type (Instrument, Reagent, and Services & Software), By Application (Food & Detergent Industries, Environment, Medical, Biopolymer Production, and Nano Biotechnology), By Method (Rational Protein Design, Directed, and Evolution), By End User (Pharmaceutical & Biotechnology Companies, Contract Engineering Organizations, and Academic Research Institutes), and By Region (North America, Europe, Asia-Pacific, and Rest Of The World) –Market Forecast Till 2035

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    Protein Engineering Market Infographic
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    Protein Engineering Market Summary

    The Global Protein Engineering Market is projected to grow from 1.90 USD Billion in 2024 to 6.48 USD Billion by 2035.

    Key Market Trends & Highlights

    Protein Engineering Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 11.81% from 2025 to 2034.
    • By 2035, the market valuation is anticipated to reach 6.48 USD Billion, indicating substantial growth potential.
    • in 2024, the market is valued at 1.90 USD Billion, reflecting the current investment landscape in protein engineering.
    • Growing adoption of advanced biotechnological techniques due to increasing demand for novel therapeutics is a major market driver.

    Market Size & Forecast

    2024 Market Size 1.90 (USD Billion)
    2035 Market Size 6.48 (USD Billion)
    CAGR (2025-2035) 11.80%

    Major Players

    Agilent Technologies, AB-Sciex, Bio-Rad Laboratories, Inc., Bruker Corp., GE Healthcare, Perkin Elmer, Sigma-Aldrich Corp., Thermo Fisher Scientific, Waters Corp.

    Protein Engineering Market Trends

    Increasing demand for treatments and medications based on proteins drives market growth

    Market CAGR for protein engineering is being driven by the rising need for treatments and medications based on proteins over the forecast period, and market for protein engineering, which is extremely dependent on the rising need for proteins made from proteins. Biologics, or proteins-based medications, treat various illnesses like cancer, autoimmune conditions, and uncommon genetic disorders. Drugs based on proteins have several benefits over conventional small-molecule medications. As they are created to interact with particular targets in the body, they are frequently more selective and have fewer adverse effects.

    Additionally, protein-based medications have a lower likelihood of being metabolized by the liver, which can increase their effectiveness and lower the possibility of toxicity. These benefits have led to a huge increase in the demand for protein-based medicines on the international market. Many variables, such as the rising prevalence of chronic diseases, aging populations, and rising healthcare costs, influence this rise. The desire for new and improved therapeutics is mostly driven by the increased prevalence of chronic diseases like cancer, diabetes, and cardiovascular problems.

    In addition, it is projected that the market would grow significantly as a result of the rising number of government programmes meant to advance the field of protein engineering. As a result, there has been a growth in this field's R&D spending, amount of funds awarded, and research and development programs. For instance, Nabla Bio reported that a USD 11 million seed fundraising round would be completed in December 2021. With the aid of this funding, a platform for AI-first design will be created, paving the way for new antibody therapies.

    Likewise, Generate Biomedicines, and Amgen confirmed A research partnership agreement to create protein therapeutics for 5 clinical targets in January 2022. The demand for protein engineering is being driven by the rise in chronic & lifestyle diseases like diabetes, cardiovascular disorders, and others. As a result, it is anticipated that the demand for protein engineering will increase throughout the projection period due to the high demand for treatments and medications. Thus, driving the protein engineering market revenue.

    The ongoing advancements in protein engineering are poised to revolutionize therapeutic development, enhancing the precision of drug design and delivery mechanisms.

    National Institutes of Health (NIH)

    Protein Engineering Market Drivers

    Market Growth Projections

    The Global Protein Engineering Market Industry is projected to experience substantial growth in the coming years. With a market value of 1.9 USD Billion in 2024, it is anticipated to reach 6.48 USD Billion by 2035, reflecting a robust CAGR of 11.81% from 2025 to 2035. This growth trajectory is indicative of the increasing importance of protein engineering across various sectors, including pharmaceuticals, agriculture, and industrial applications. The market's expansion is likely to be driven by ongoing technological advancements, rising demand for biopharmaceuticals, and the growing recognition of engineered proteins' potential to address complex challenges in health and industry.

    Regulatory Support and Frameworks

    Regulatory support is an essential factor influencing the Global Protein Engineering Market Industry. Governments worldwide are establishing frameworks that facilitate the approval and commercialization of engineered proteins, particularly in the biopharmaceutical sector. These regulations aim to ensure safety and efficacy while promoting innovation. The establishment of clear guidelines encourages investment and research, as companies are more likely to engage in protein engineering initiatives when regulatory pathways are well-defined. This supportive environment is likely to enhance the market's growth, as it fosters collaboration between regulatory bodies and industry stakeholders, ultimately benefiting public health.

    Rising Demand for Biopharmaceuticals

    The Global Protein Engineering Market Industry is experiencing a notable surge in demand for biopharmaceuticals, driven by advancements in personalized medicine and targeted therapies. As of 2024, the market is valued at approximately 1.9 USD Billion, reflecting the increasing reliance on engineered proteins for drug development. This trend is expected to continue, with projections indicating a market growth to 6.48 USD Billion by 2035. The compound annual growth rate (CAGR) of 11.81% from 2025 to 2035 underscores the potential of protein engineering in producing innovative therapeutics that cater to specific patient needs.

    Growing Applications in Industrial Biotechnology

    The Global Protein Engineering Market Industry is witnessing an expansion in applications beyond healthcare, particularly in industrial biotechnology. Engineered proteins are increasingly utilized in various sectors, including agriculture, food production, and environmental management. For example, enzymes developed through protein engineering are employed in biofuels and bioremediation processes, showcasing their versatility. This diversification of applications is expected to contribute to the market's growth trajectory, as industries seek sustainable and efficient solutions. The ongoing exploration of protein engineering in industrial contexts suggests a promising future for the market, with potential for significant economic impact.

    Increasing Investment in Research and Development

    Investment in research and development is a critical driver for the Global Protein Engineering Market Industry. Governments and private entities are allocating substantial resources to explore the therapeutic applications of engineered proteins. This trend is evident in various initiatives aimed at fostering innovation in biotechnology. For instance, funding programs targeting protein engineering research have been established, leading to breakthroughs in drug discovery and development. The anticipated growth of the market from 1.9 USD Billion in 2024 to 6.48 USD Billion by 2035 highlights the importance of sustained investment in R&D, which is essential for advancing the field and addressing unmet medical needs.

    Technological Advancements in Protein Engineering

    Technological innovations play a pivotal role in shaping the Global Protein Engineering Market Industry. The advent of high-throughput screening and computational modeling techniques has revolutionized the way proteins are engineered. These advancements facilitate the rapid identification and optimization of protein structures, enhancing their efficacy and stability. As a result, companies are increasingly investing in research and development to harness these technologies, thereby driving market growth. The integration of artificial intelligence and machine learning into protein design processes further amplifies the potential for creating novel proteins with desirable characteristics, positioning the industry for sustained expansion.

    Market Segment Insights

    Protein Engineering Type Insights

    The market segments of protein engineering, based on type, includes instruments, reagents, and services & software. The instrumentS segment dominated the market, accounting for 51.50% of market revenue (0.77 Billion). Demand for this market segment is being driven by the growing preference among researchers for automated methods for encouraging quick molecular development processes.

    Protein Engineering Application Insights

    The protein engineering market segmentation, based on application, includes food & detergent Industries, environment, medical, biopolymer production, and

    . The nanobiotechnology category generated the most income (35%). This is due to the widespread use of hybrid techniques, which combine directed evolution and rational design, for various purposes, such as improving redox proteins and enzymes. The fabrication of nano-devices for biosensing and other significant nanotechnology engineering applications places a high value on these enzymes, boosting the chances for future growth.

    Protein Engineering Route Administration Insights

    The market segmentation of protein engineering, based on method, includes rational protein design and directed evolution. The rational protein design segment dominated the market, accounting for 58% of market revenue. The technology's vast application in enzyme engineering and antibody development accounts for the dominant share. Enzyme engineering has seen a tremendous increase in its commercial uses, which has led to the creation of improved and modified enzymes with the appropriate catalytic capabilities.

    Protein Engineering End User Insights

    The  protein engineering market segmentation, based on end-users, includes pharmaceuticals & biotechnology companies, contract engineering organizations, and academic research institutes. The pharmaceuticals & biotechnology companies segment dominated the market, accounting for 52% of market revenue. The segment is expanding due to more and more in silico drug discovery models being used to treat neurological issues, cancer, and diabetes. These companies continuously attempt to preserve their market position by creating drug versions of patent-expiring pharmaceuticals utilizing a computer modeling technique.

    Get more detailed insights about Protein Engineering Market Research Report - Forecast till 2034

    Regional Insights

    By region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. The North American protein engineering market will dominate this market, owing to the presence of numerous market players and their varied strategic efforts.

    Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

    Europe's Protein Engineering market accounts for the second-largest market share due to the availability of a sizable population base for the development and clinical testing of protein engineering applications. Further, the German market of protein engineering held the largest market share, and the UK market of protein engineering was the second-largest growing market in the European region.

    The Asia-Pacific protein engineering market is expected to grow at the fastest CAGR from 2023 to 2032. This is due to the high prevalence of autoimmune, cardiovascular, and cancer diseases in developing Asian nations. Due to the significant economic development in emerging countries like India and China, unexplored potential in this region is also anticipated to help the sector thrive. Moreover, China’s market of protein engineering held the largest market share, and the Indian market of protein engineering was the fastest-growing market in the Asia-Pacific region.

    Key Players and Competitive Insights

    Leading market players are investing heavily in research and development to expand their product lines, which will help the market of protein engineering, grow even more. Market participants are also engaging in a variety of strategic measures in order to grow their businesses  presence, with significant market development such as new product releases, contractual agreements, mergers and acquisitions, increased investments, and so on partnerships with other organisations. The protein engineering industry must offer cost-effective items to expand and survive in a more competitive and developing market condition.

    One of the most important company strategies is to manufacture locally to save operational costs. manufacturers use in the  protein engineering industry to benefit clients and increase the market sector. In recent years, the protein engineering industry has provided some of the greatest significant benefits to medicine. Major players in the protein engineering market, including Agilent Technologies (U.S.), AB-Sciex (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S).

    Agilent Technologies, Inc. offers fundamental bio-analytical and electronic measurement solutions to the chemical analysis, communications, electronics, and life sciences industries. The business provides semiconductor and board testing and electronic and bioanalytical measurements. In October 2020, The Agilent Seahorse XFp Analyzer, a device for assessing metabolic activity in living cells that can be utilized in protein engineering research, was introduced by Agilent Technologies.

    AbbVie Inc. researches and develops pharmaceutical products. The company produces pharmaceutical medications for specialized treatment fields like immunology, chronic renal disease, hepatitis C, women's health, oncology, and neuroscience. Multiple sclerosis, Parkinson's, and

    are just a few of the illnesses that AbbVie treats. In March 2022, for treating moderately to highly active ulcerative colitis, the U.S. FDA gave AbbVie Inc. permission to use RINVOQ (upadacitinib), a new medication.

    Key Companies in the Protein Engineering Market market include

    Industry Developments

    • Q2 2024: GenScript Launches New Protein Engineering Platform to Accelerate Antibody Drug Discovery GenScript Biotech announced the launch of its next-generation protein engineering platform designed to streamline and accelerate the discovery and optimization of antibody therapeutics, offering enhanced capabilities for pharmaceutical partners.
    • Q2 2024: Codexis Announces Strategic Partnership with Nestlé Health Science for Enzyme Engineering Codexis entered into a multi-year collaboration with Nestlé Health Science to engineer novel enzymes for use in medical nutrition products, leveraging Codexis’s protein engineering expertise to develop customized solutions.
    • Q2 2024: Thermo Fisher Scientific Opens New Protein Engineering Center in Massachusetts Thermo Fisher Scientific inaugurated a state-of-the-art protein engineering facility in Massachusetts, aimed at expanding its capabilities in biologics development and supporting pharmaceutical clients with advanced protein design services.
    • Q3 2024: Bruker Acquires Protein Engineering Startup Evozyne for $150 Million Bruker announced the acquisition of Evozyne, a Chicago-based protein engineering company specializing in AI-driven enzyme design, to strengthen its biopharma solutions portfolio.
    • Q3 2024: Danaher Launches Protein Engineering Innovation Hub in Switzerland Danaher Corporation opened a new innovation hub in Switzerland focused on protein engineering, aiming to foster collaboration with European biotech firms and accelerate the development of next-generation biologics.
    • Q3 2024: Absci Raises $100 Million in Series D Funding to Expand AI Protein Engineering Platform Absci secured $100 million in Series D financing to scale its AI-powered protein engineering platform, with the goal of accelerating drug discovery partnerships with major pharmaceutical companies.
    • Q4 2024: Eli Lilly and Company Announces FDA Approval for Engineered Insulin Analog Eli Lilly received FDA approval for its newly engineered insulin analog, developed using advanced protein engineering techniques to improve efficacy and reduce dosing frequency for diabetes patients.
    • Q4 2024: GenScript and Merck KGaA Enter Strategic Collaboration for Protein Therapeutics GenScript Biotech and Merck KGaA announced a strategic partnership to co-develop engineered protein therapeutics, combining GenScript’s protein engineering platforms with Merck’s clinical development expertise.
    • Q1 2025: Novo Nordisk Opens New Protein Engineering R&D Center in Denmark Novo Nordisk inaugurated a new research and development center dedicated to protein engineering in Denmark, aiming to accelerate the discovery of next-generation protein-based therapeutics for metabolic diseases.
    • Q1 2025: Thermo Fisher Scientific Acquires Protein Engineering Firm Ingenza Thermo Fisher Scientific completed the acquisition of Ingenza, a UK-based protein engineering company, to enhance its synthetic biology and enzyme engineering capabilities for biopharmaceutical manufacturing.
    • Q2 2025: ElevateBio Announces $200 Million Series C Funding to Advance Cell and Protein Engineering Platforms ElevateBio raised $200 million in Series C funding to expand its cell and protein engineering platforms, supporting the development of novel gene and cell therapies.
    • Q2 2025: Bio-Rad Laboratories Appoints New Head of Protein Engineering Division Bio-Rad Laboratories announced the appointment of Dr. Maria Chen as the new head of its protein engineering division, signaling a strategic focus on expanding its biologics and enzyme engineering business.

    Future Outlook

    Protein Engineering Market Future Outlook

    The Protein Engineering Market is projected to grow at 11.80% CAGR from 2024 to 2034, driven by advancements in biotechnology, increasing demand for personalized medicine, and rising investments in research and development.

    New opportunities lie in:

    • Develop novel enzyme-based therapies for chronic diseases. Leverage AI for protein design to enhance efficiency. Expand biomanufacturing capabilities to meet growing demand.

    By 2035, the Protein Engineering Market is expected to be a pivotal sector, reflecting robust growth and innovation.

    Market Segmentation

    Protein Engineering Type Outlook

    • Instrument
    • Reagent
    • Services & Software

    Protein Engineering Method Outlook

    • Rational Protein Design
    • Directed Evolution

    Protein Engineering End User Outlook

    • Pharmaceutical & Biotechnology Companies
    • Contract Engineering Organizations
    • Academic Research Institutes

    Protein Engineering Regional Outlook

    • US
    • Canada
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    • Middle East
    • Africa
    • Latin America

    Protein Engineering Application Outlook

    • Food & Detergent Industries
    • Environment
    • Medical
    • Biopolymer Production
    • Nano Biotechnology

    Report Scope

    Attribute/Metric Details
    Market Size 2024    1.90 (USD Billion)
    Market Size 2025    2.12 (USD Billion)
    Market Size 2035 6.48 (USD Billion)
    Compound Annual Growth Rate (CAGR) 11.80% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2020 - 2024
    Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments Covered Type, Application, Method, End User, and Region
    Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
    Countries Covered The US, Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
    Key Companies Profiled Agilent Technologies (U.S.), AB-Sciex (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S)
    Key Market Opportunities Developing protein engineering markets
    Key Market Dynamics Rising incidence of chronic illnessesGrowing financial support for synthetic biology

    Market Highlights

    Author
    Kinjoll Dey
    Research Analyst Level I

    He is an extremely curious individual currently working in Healthcare and Medical Devices Domain. Kinjoll is comfortably versed in data centric research backed by healthcare educational background. He leverages extensive data mining and analytics tools such as Primary and Secondary Research, Statistical Analysis, Machine Learning, Data Modelling. His key role also involves Technical Sales Support, Client Interaction and Project management within the Healthcare team. Lastly, he showcases extensive affinity towards learning new skills and remain fascinated in implementing them.

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    FAQs

    How much is the protein engineering market?

    The protein engineering market size was valued at USD 1.90 Billion in 2024.

    What is the growth rate of the protein engineering market?

    The market is projected to grow at a CAGR of 11.80% during the forecast period, 2025 - 2034

    Which region held the largest market share in the protein engineering market?

    North America had the largest share of the market

    Who are the key players in the protein engineering market?

    The key players in the market are AB-Sciex (U.S.), Agilent Technologies (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S).

    Which Type led the protein engineering market?

    The instrument category dominated the market in 2022.

    Which application led the protein engineering market?

    The nanobiotechnology category dominated the market in 2022.

    Which method led the protein engineering market?

    The rational protein design category dominated the market in 2022.

    Which End User had the largest market share in the protein engineering market?

    Pharmaceutical & biotechnology companies had the largest share of the market.

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