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    South America Car T Cell Therapy Market

    ID: MRFR/Pharma/48114-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    South America CAR T Cell Therapy Market Research Report By Therapeutic Area (Oncology, Autoimmune Diseases, Infectious Diseases), By Cell Source (Autologous, Allogeneic, Gene-Edited), By Indication (Acute Lymphoblastic Leukemia, Non-Hodgkin Lymphoma, Multiple Myeloma), By End-user (Hospitals, Research Institutes, Cancer Treatment Centers), and By Regional (Brazil, Mexico, Argentina, Rest of South America) - Forecast to 2035

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    South America Car T Cell Therapy Market Infographic
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    South America Car T Cell Therapy Market Summary

    As per MRFR analysis, the South America car t-cell-therapy market Size was estimated at 461.9 USD Million in 2024. The South America car t-cell-therapy market is projected to grow from 533.4 USD Million in 2025 to 2249.8 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 15.48% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The South America car T-cell therapy market is poised for substantial growth driven by increasing investments and regulatory support.

    • Brazil remains the largest market for car T-cell therapy, reflecting a robust healthcare infrastructure and investment in biotechnology.
    • Mexico is emerging as the fastest-growing region, with a notable increase in clinical trial activities and patient access to innovative therapies.
    • The market is witnessing a surge in research and development investments, indicating a strong commitment to advancing cellular therapies.
    • Key drivers such as the rising incidence of hematological malignancies and advancements in cellular therapy technologies are propelling market growth.

    Market Size & Forecast

    2024 Market Size 461.9 (USD Million)
    2035 Market Size 2249.8 (USD Million)

    Major Players

    Novartis (CH), Gilead Sciences (US), Bristol-Myers Squibb (US), Celgene (US), Amgen (US), Merck & Co. (US), AstraZeneca (GB), Janssen Pharmaceuticals (US), Roche (CH)

    South America Car T Cell Therapy Market Trends

    The CAR T-cell therapy market is currently experiencing notable growth in South America. This growth is driven by advancements in biotechnology and increasing investments in healthcare infrastructure. The region's rising prevalence of hematological malignancies has led to a heightened demand for innovative treatment options, including car t-cell therapies. Furthermore, collaborations between local research institutions and international pharmaceutical companies are fostering the development of tailored therapies that address the unique needs of South American populations. Regulatory bodies are also becoming more supportive, streamlining approval processes for new therapies, which may enhance market accessibility. In addition, the car t-cell-therapy market is witnessing a surge in clinical trials across South America, reflecting a commitment to advancing research and improving patient outcomes. The growing awareness of the benefits of personalized medicine is encouraging healthcare providers to adopt these therapies, potentially leading to improved survival rates for patients with complex conditions. As the market evolves, it appears that the integration of advanced technologies, such as artificial intelligence and machine learning, could further optimize treatment protocols and patient management strategies, thereby enhancing the overall efficacy of car t-cell therapies in the region.

    Increasing Investment in Research and Development

    There is a noticeable trend of rising investment in research and development within the car t-cell-therapy market. This investment is primarily driven by both public and private sectors aiming to enhance therapeutic options. Local governments are providing funding to support innovative projects, while pharmaceutical companies are allocating resources to develop new therapies tailored to regional needs.

    Regulatory Support and Streamlining

    Regulatory bodies in South America are increasingly supportive of the car t-cell-therapy market. Efforts to streamline approval processes for new therapies are evident, which may facilitate quicker access to innovative treatments for patients. This regulatory environment is likely to encourage more companies to enter the market, fostering competition and innovation.

    Growing Clinical Trial Activity

    The car t-cell-therapy market is experiencing a surge in clinical trial activity across South America. This trend indicates a strong commitment to advancing research and improving treatment options. Increased participation in clinical trials may lead to the development of therapies that are specifically designed to meet the needs of the local population, potentially enhancing patient outcomes.

    South America Car T Cell Therapy Market Drivers

    Increasing Healthcare Expenditure

    The CAR T-cell therapy market in South America is benefiting from rising healthcare expenditure in several countries within the region. Governments and private sectors are allocating more funds towards innovative treatments, with healthcare spending projected to grow by approximately 6% annually. This financial commitment is likely to facilitate the adoption of advanced therapies, including CAR T-cell therapy, as healthcare systems strive to improve patient outcomes. The car t-cell-therapy market stands to gain from this trend, as enhanced funding can lead to better infrastructure, training for healthcare professionals, and access to cutting-edge therapies. Moreover, as more patients gain access to these treatments, the overall demand for CAR T-cell therapies is expected to rise, further driving market growth.

    Growing Patient Advocacy and Awareness

    The car t-cell-therapy market in South America is witnessing a rise in patient advocacy and awareness initiatives, which are crucial for driving market growth. Advocacy groups are increasingly educating patients about CAR T-cell therapy and its potential benefits, leading to higher demand for these treatments. As awareness increases, patients are more likely to seek out advanced therapies, prompting healthcare providers to incorporate CAR T-cell options into their treatment protocols. The car t-cell-therapy market is likely to see a positive impact from this trend, as greater patient engagement can lead to improved treatment outcomes and a more informed patient population. Additionally, as advocacy efforts continue to grow, they may influence policy changes that support the development and accessibility of CAR T-cell therapies in South America.

    Advancements in Cellular Therapy Technologies

    Technological advancements in cellular therapies are significantly impacting the car t-cell-therapy market in South America. Innovations in genetic engineering and cell processing techniques have improved the efficacy and safety profiles of CAR T-cell therapies. For instance, the development of next-generation CAR T-cells, which utilize novel co-stimulatory domains, has shown promising results in clinical trials. This progress is likely to attract investment and interest from pharmaceutical companies, further propelling the car t-cell-therapy market. Additionally, the integration of artificial intelligence in treatment planning and patient monitoring may enhance therapeutic outcomes, making CAR T-cell therapy a more viable option for patients in South America. As these technologies continue to evolve, they could potentially reshape the landscape of cancer treatment in the region.

    Rising Incidence of Hematological Malignancies

    The CAR T-cell therapy market in South America is growing due to the rising incidence of hematological malignancies, including leukemia and lymphoma. According to recent data, the region has seen an increase in these conditions, with estimates suggesting that around 50,000 new cases are diagnosed annually. This surge in cancer cases necessitates innovative treatment options, thereby driving demand for advanced therapies like CAR T-cell therapy. The car t-cell-therapy market is poised to benefit from this trend, as healthcare providers seek effective solutions to combat these life-threatening diseases. Furthermore, the increasing awareness among patients and healthcare professionals about the potential of CAR T-cell therapy is likely to enhance its adoption, contributing to market expansion in South America.

    Collaborations and Partnerships in the Biotech Sector

    Collaborations and partnerships among biotech firms, research institutions, and healthcare providers are emerging as a key driver for the car t-cell-therapy market in South America. These alliances facilitate knowledge sharing, resource pooling, and accelerated development of CAR T-cell therapies. For instance, joint ventures between local biotech companies and international pharmaceutical firms are likely to enhance research capabilities and expedite clinical trials. The car t-cell-therapy market is expected to benefit from these collaborations, as they can lead to the introduction of innovative therapies tailored to the specific needs of South American patients. Furthermore, such partnerships may also improve regulatory navigation, ensuring that new therapies reach the market more efficiently.

    Market Segment Insights

    By Therapeutic Area: Oncology (Largest) vs. Autoimmune Diseases (Fastest-Growing)

    In the South America car t-cell-therapy market, Oncology represents the largest therapeutic area, commanding a significant portion of the market share. Autoimmune Diseases, while smaller in market share compared to Oncology, is witnessing increased investment and research, positioning it as a rapidly emerging segment. Infectious Diseases follows but lags behind both in terms of market presence and growth dynamics. The growth trends are largely driven by advancements in research and technology, alongside increasing approvals of car t-cell therapies in Oncology. The rising prevalence of cancer and autoimmune disorders in the region has also contributed to the expansion of these segments. Regulatory support and collaborations with biotech firms further enhance the market potential for these therapeutic areas.

    Oncology (Dominant) vs. Autoimmune Diseases (Emerging)

    Oncology is the dominant therapeutic area, driven by a strong clinical pipeline and a high patient population suffering from various cancers. This segment benefits from extensive research backing and considerable funding directed towards innovative therapies. On the other hand, Autoimmune Diseases are emerging as a significant player, spurred by increasing recognition of unmet medical needs and growing awareness of treatments. This segment is characterized by a surge in clinical trials and collaborations, reflecting a shift in healthcare focus. Both segments are on a trajectory for growth, yet their dynamics differ, with Oncology holding a more established market presence while Autoimmune Diseases are rapidly gaining ground and investment.

    By Cell Source: Autologous (Largest) vs. Allogeneic (Fastest-Growing)

    In the South America car t-cell-therapy market, Autologous cell therapies hold the largest market share, attributed to their personalized treatment approach and established clinical success. Allogeneic therapies, while currently smaller in share, are rapidly gaining traction due to their potential for off-the-shelf treatments, appealing to a broader patient demographic. Growth trends indicate a rising interest in both Autologous and Allogeneic therapies, driven by advances in genetic engineering and improved manufacturing technologies. Gene-Edited therapies are emerging as innovative solutions, representing the forefront of research and development. Increased investments and collaborations in the biotechnology sector are fueling this growth, with Allogeneic therapies likely to dominate future market dynamics as they continue to improve efficacy and accessibility.

    Autologous (Dominant) vs. Allogeneic (Emerging)

    Autologous therapies, representing the dominant force in the market, are characterized by their reliance on a patient's own cells for treatment, which minimizes the risk of rejection and enhances personalized care. This segment has seen steady growth due to favorable clinical outcomes and strong patient acceptance levels. On the other hand, Allogeneic therapies, noted as emerging, utilize donor cells, allowing for greater scalability and more immediate treatment options for patients. The ability to develop these therapies as off-the-shelf products positions them as a competitive alternative, driving interest from healthcare providers and investors alike. Together, these segments exemplify the dynamic nature of the cell therapy landscape in South America.

    By Indication: Acute Lymphoblastic Leukemia (Largest) vs. Non-Hodgkin Lymphoma (Fastest-Growing)

    In the South America car t-cell-therapy market, Acute Lymphoblastic Leukemia (ALL) takes the lead as the dominant indication, capturing the largest share of the market. Following closely, Non-Hodgkin Lymphoma (NHL) showcases significant growth potential, driven by increasing prevalence and rising demand for effective treatment options. Multiple Myeloma, while present, holds a smaller position in comparison to the other indications. The growth trends in this segment are largely influenced by advancements in CAR T-cell therapies that target hematological malignancies, coupled with increased investment in research and development. The emerging need for personalized medicine and innovative treatment modalities in South America is facilitating rapid growth for NHL. Additionally, a growing patient population and supportive regulatory frameworks are anticipated to further bolster the market for all three indications.

    Acute Lymphoblastic Leukemia (Dominant) vs. Non-Hodgkin Lymphoma (Emerging)

    Acute Lymphoblastic Leukemia (ALL) remains the dominant segment in the South America car t-cell-therapy market due to its high prevalence rates and established treatment protocols. The effectiveness of CAR T-cell therapies in treating ALL has resulted in significant advancements and success stories that resonate with healthcare professionals and patients alike. Conversely, Non-Hodgkin Lymphoma (NHL) is marked as an emerging player, experiencing rapid growth driven by ongoing clinical trials and the introduction of innovative therapies tailored for this indication. Both segments are characterized by their unique patient demographics and treatment methodologies, which are crucial in shaping therapeutic strategies in the region.

    By End User: Hospitals (Largest) vs. Cancer Treatment Centers (Fastest-Growing)

    In the South America car t-cell-therapy market, hospitals currently lead the end user segment, commanding a significant market share due to their essential role in delivering advanced cancer therapies. These healthcare facilities are equipped with the necessary infrastructure and specialized personnel to administer complex treatments, making them a principal hub for CAR T-cell therapy applications. Conversely, cancer treatment centers are rapidly gaining traction, reflecting an upward growth trajectory as they focus on innovative cancer treatments tailored to patient needs. The growth of the end user segment is primarily driven by the increasing incidence of cancer and the subsequent rise in demand for effective treatment options. Research institutes play a pivotal role in this dynamics by advancing CAR T-cell therapy research and collaborating with hospitals and treatment centers. As awareness about CAR T-cell therapies expands, and with support from health authorities, both hospitals and cancer treatment centers are expected to see significant growth, positioning them as key players in the region's healthcare landscape.

    Hospitals (Dominant) vs. Cancer Treatment Centers (Emerging)

    Hospitals serve as the dominant end user in the car t-cell-therapy market, providing comprehensive cancer treatment and hosting specialized facilities that enhance patient care. They are well-positioned to integrate CAR T-cell therapies into their treatment protocols due to established infrastructure and highly skilled personnel. On the other hand, cancer treatment centers are emerging as a vital component in the healthcare ecosystem, particularly for patients seeking novel therapeutic options. These centers are centered around patient-centric care and often adopt a more personalized approach, which is increasingly appealing in today's healthcare environment. As the demand for innovative cancer therapies rises, both segments are likely to grow, albeit with hospitals maintaining a leading position in terms of overall market share.

    Get more detailed insights about South America Car T Cell Therapy Market

    Regional Insights

    Brazil : Strong Growth and Innovation Hub

    Brazil holds a dominant position in the South American car T-cell therapy market, with a market value of $210.95 million, representing a significant share. Key growth drivers include increasing cancer prevalence, advancements in healthcare infrastructure, and supportive government policies promoting innovative therapies. The demand for personalized medicine is rising, supported by regulatory frameworks that facilitate faster approvals for new treatments, enhancing patient access to cutting-edge therapies.

    Mexico : Growing Demand and Investment Opportunities

    Mexico's car T-cell therapy market is valued at $90.45 million, reflecting a growing interest in advanced cancer treatments. The market is driven by increasing investments in healthcare infrastructure and a rising number of clinical trials. Demand trends indicate a shift towards personalized therapies, with government initiatives aimed at improving healthcare access. Regulatory bodies are also streamlining approval processes for innovative treatments, fostering a conducive environment for market growth.

    Argentina : Focus on Patient-Centric Solutions

    Argentina's car T-cell therapy market is valued at $75 million, showcasing a burgeoning interest in advanced cancer treatments. Key growth drivers include a rising incidence of hematological malignancies and increased healthcare spending. The government is actively promoting research and development in biotechnology, which is crucial for the adoption of innovative therapies. Regulatory frameworks are evolving to support faster approvals, enhancing the market's attractiveness for new entrants.

    Rest of South America : Regional Growth and Collaboration Potential

    The Rest of South America holds a market value of $85.5 million in car T-cell therapy, with diverse opportunities across various countries. Growth is driven by increasing healthcare investments and collaborative efforts among regional players. Demand for advanced cancer therapies is rising, supported by government initiatives aimed at improving healthcare access. Regulatory environments are becoming more favorable, encouraging innovation and market entry for new therapies.

    Key Players and Competitive Insights

    The car t-cell-therapy market in South America is characterized by a dynamic competitive landscape, driven by increasing incidences of hematological malignancies and a growing emphasis on personalized medicine. Major players such as Novartis (CH), Gilead Sciences (US), and Bristol-Myers Squibb (US) are at the forefront, each adopting distinct strategies to enhance their market presence. Novartis (CH) focuses on innovation through continuous research and development, particularly in expanding its CAR-T offerings. Gilead Sciences (US) emphasizes strategic partnerships to bolster its product pipeline, while Bristol-Myers Squibb (US) is concentrating on regional expansion to tap into emerging markets. Collectively, these strategies contribute to a competitive environment that is increasingly collaborative yet fiercely competitive.

    Key business tactics within this market include localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. The competitive structure appears moderately fragmented, with several key players exerting influence over market dynamics. This fragmentation allows for a variety of therapeutic options, catering to diverse patient needs while fostering innovation through competition.

    In October 2025, Novartis (CH) announced a collaboration with a local biotech firm to enhance its CAR-T manufacturing capabilities in Brazil. This strategic move is likely to streamline production processes and reduce costs, thereby improving access to therapies in the region. Such initiatives not only strengthen Novartis's operational footprint but also align with the growing demand for localized treatment options.

    In September 2025, Gilead Sciences (US) launched a new CAR-T therapy specifically targeting a rare form of leukemia, following a successful clinical trial. This launch is significant as it underscores Gilead's commitment to addressing unmet medical needs in South America, potentially capturing a larger market share. The introduction of innovative therapies is expected to enhance patient outcomes and solidify Gilead's position as a leader in the sector.

    In August 2025, Bristol-Myers Squibb (US) expanded its CAR-T therapy portfolio by acquiring a smaller firm specializing in next-generation cell therapies. This acquisition is indicative of a broader trend towards consolidation in the market, allowing Bristol-Myers Squibb to integrate advanced technologies and diversify its offerings. Such strategic actions may enhance their competitive edge and foster innovation in treatment modalities.

    As of November 2025, current trends in the car t-cell-therapy market include a pronounced shift towards digitalization and the integration of artificial intelligence in treatment development. Strategic alliances are increasingly shaping the landscape, facilitating knowledge sharing and resource pooling among companies. Looking ahead, competitive differentiation is likely to evolve, with a greater emphasis on innovation and technology rather than solely on price. The focus on supply chain reliability and the ability to deliver personalized therapies will be crucial in maintaining a competitive advantage.

    Key Companies in the South America Car T Cell Therapy Market market include

    Industry Developments

    The South America CAR T Cell Therapy Market has seen significant developments recently, particularly in Brazil and Argentina.

    In October 2023, Bristol Myers Squibb announced advancements in its CAR T Cell therapies, enhancing access to treatment for patients in these regions. Novartis continues to expand its presence in South America with plans for new clinical trials, while Eli Lilly is focusing on collaborations with local healthcare providers to facilitate therapy accessibility.

    Merck and Amgen have also made strides in strengthening their distribution networks in the region to meet increasing demand. In terms of mergers and acquisitions, Celgene has been reportedly acquiring smaller biotech firms in Brazil to boost its CAR T Cell therapy offerings as of August 2023.

    The CAR T Cell therapy market is projected to grow due to rising incidences of hematological malignancies, with Zymeworks and Gilead Sciences also emerging as key players. The Brazilian government's recent initiatives to fund innovative cancer treatments have further catalyzed the market's potential, with regulations supporting faster approvals for novel therapies.

    As a result, the South American CAR T Cell Therapy Market is gaining traction, providing new hope for patients battling cancer.

    South America CAR T

    Future Outlook

    South America Car T Cell Therapy Market Future Outlook

    The car t-cell-therapy market is projected to grow at a 15.48% CAGR from 2024 to 2035, driven by technological advancements, increasing cancer prevalence, and enhanced regulatory support.

    New opportunities lie in:

    • Development of personalized CAR T-cell therapies for niche cancer types.
    • Expansion of telehealth services for remote patient monitoring.
    • Strategic partnerships with biotech firms for innovative product pipelines.

    By 2035, the market is expected to achieve substantial growth, positioning itself as a leader in cancer treatment solutions.

    Market Segmentation

    South America Car T Cell Therapy Market End User Outlook

    • Hospitals
    • Research Institutes
    • Cancer Treatment Centers

    South America Car T Cell Therapy Market Indication Outlook

    • Acute Lymphoblastic Leukemia
    • Non-Hodgkin Lymphoma
    • Multiple Myeloma

    South America Car T Cell Therapy Market Cell Source Outlook

    • Autologous
    • Allogeneic
    • Gene-Edited

    South America Car T Cell Therapy Market Therapeutic Area Outlook

    • Oncology
    • Autoimmune Diseases
    • Infectious Diseases

    Report Scope

    MARKET SIZE 2024461.9(USD Million)
    MARKET SIZE 2025533.4(USD Million)
    MARKET SIZE 20352249.8(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR)15.48% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Million
    Key Companies Profiled["Novartis (CH)", "Gilead Sciences (US)", "Bristol-Myers Squibb (US)", "Celgene (US)", "Amgen (US)", "Merck & Co. (US)", "AstraZeneca (GB)", "Janssen Pharmaceuticals (US)", "Roche (CH)"]
    Segments CoveredTherapeutic Area, Cell Source, Indication, End User
    Key Market OpportunitiesEmerging regulatory frameworks enhance access to innovative therapies in the car t-cell-therapy market.
    Key Market DynamicsEmerging regulatory frameworks in South America are fostering innovation in the car T-cell therapy market.
    Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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    FAQs

    What is the projected market size of the South America CAR T Cell Therapy market in 2024?

    The South America CAR T Cell Therapy market is projected to reach a value of 462.0 million USD in 2024.

    What is the expected market value for the South America CAR T Cell Therapy market by 2035?

    By 2035, the South America CAR T Cell Therapy market is expected to be valued at 2250.0 million USD.

    What is the expected CAGR for the South America CAR T Cell Therapy market from 2025 to 2035?

    The South America CAR T Cell Therapy market is expected to grow at a CAGR of 15.479% from 2025 to 2035.

    Which therapeutic area holds the largest share in the South America CAR T Cell Therapy market?

    Oncology is the dominant therapeutic area, valued at 276.0 million USD in 2024 and expected to reach 1300.0 million USD by 2035.

    What are the expected market values for Autoimmune Diseases and Infectious Diseases in 2024?

    The Autoimmune Diseases segment is expected to reach 115.0 million USD and the Infectious Diseases segment at 71.0 million USD in 2024.

    Which South American country is projected to have the largest CAR T Cell Therapy market in 2024?

    Brazil is projected to have the largest CAR T Cell Therapy market, valued at 150.0 million USD in 2024.

    What will be the market value for Mexico's CAR T Cell Therapy segment by 2035?

    Mexico's CAR T Cell Therapy market is anticipated to reach a value of 550.0 million USD by 2035.

    Who are the key players in the South America CAR T Cell Therapy market?

    Major players include Bristol Myers Squibb, Novartis, Celgene, and Takeda among others.

    What is the expected market size for the Rest of South America region in 2035?

    The Rest of South America is expected to reach a market size of 650.0 million USD by 2035.

    What factors are driving the growth of the CAR T Cell Therapy market in South America?

    Key growth drivers include advancements in CAR T cell therapies and an increasing prevalence of cancer and autoimmune diseases.

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