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South America Organ On Chip Market

ID: MRFR/MED/49556-HCR
200 Pages
Rahul Gotadki
October 2025

South America Organ-On-Chip Market Research Report By Organ Type (Lung-on-Chip, Heart-on-Chip, Liver-on-Chip, Intestine-on-Chip, Kidney-on-Chip, Human-on-Chip), By Application (Drug Discovery, Toxicology Research, Others), By End-User (Pharmaceutical Companies, Research Organizations, Others) andBy Regional (Brazil, Mexico, Argentina, Rest of South America)- Forecast to 2035

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South America Organ On Chip Market Infographic
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South America Organ On Chip Market Summary

As per MRFR analysis, the South America organ on-chip market size was estimated at 32.85 USD Million in 2024. The South America organ on-chip market is projected to grow from 34.08 USD Million in 2025 to 49.1 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 3.72% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The South America organ on-chip market is poised for substantial growth driven by technological advancements and regulatory support.

  • Brazil remains the largest market for organ on-chip technologies, reflecting a robust investment landscape in biotechnology.
  • Mexico is emerging as the fastest-growing region, indicating a rising interest in innovative healthcare solutions.
  • Collaborative research initiatives are gaining traction, fostering partnerships between academia and industry to enhance product development.
  • The growing demand for personalized medicine and advancements in microfabrication techniques are key drivers propelling market expansion.

Market Size & Forecast

2024 Market Size 32.85 (USD Million)
2035 Market Size 49.1 (USD Million)

Major Players

Emulate (US), TissUse (DE), Mimetas (NL), Organovo (US), Synlogic (US), Hesperos (US), InSphero (CH), Reinnervate (GB), Tissot (FR)

South America Organ On Chip Market Trends

The organ on-chip market is currently experiencing notable growth in South America, driven by advancements in biotechnology and increasing demand for innovative drug testing methods. This region is witnessing a surge in research initiatives aimed at developing more effective and ethical alternatives to traditional animal testing. The integration of organ-on-chip technology into pharmaceutical research is becoming more prevalent, as it offers the potential for more accurate predictions of human responses to drugs. Furthermore, collaborations between academic institutions and industry players are fostering innovation and accelerating the adoption of these technologies. In addition, regulatory bodies in South America are beginning to recognize the value of organ-on-chip systems in enhancing drug development processes. This recognition is likely to lead to more supportive policies and funding opportunities for research and development in this field. As the organ on-chip market continues to evolve, it appears poised to play a crucial role in the future of personalized medicine and therapeutic development in the region. The ongoing efforts to establish a robust ecosystem for organ-on-chip technologies suggest a promising outlook for stakeholders involved in this market.

Rising Investment in Biotechnology

There is an increasing trend of investment in biotechnology within South America, particularly in the organ on-chip market. This influx of funding is likely to enhance research capabilities and facilitate the development of innovative technologies. As more stakeholders recognize the potential of organ-on-chip systems, financial support is expected to grow, fostering advancements in this area.

Regulatory Support and Framework Development

Regulatory bodies in South America are beginning to establish frameworks that support the use of organ-on-chip technologies. This trend indicates a shift towards more favorable policies that could streamline the approval processes for new drugs and therapies. Such regulatory support may encourage more companies to invest in organ-on-chip research and development.

Collaborative Research Initiatives

Collaborative efforts between universities, research institutions, and industry players are becoming increasingly common in South America. These partnerships are likely to accelerate the development and application of organ-on-chip technologies. By pooling resources and expertise, stakeholders can enhance innovation and drive the market forward.

South America Organ On Chip Market Drivers

Support from Government Initiatives

Government initiatives in South America are playing a crucial role in shaping the organ on-chip market. Various funding programs and grants aimed at promoting biotechnology research are being introduced, which directly benefit the development of organ-on-chip technologies. For instance, several South American countries have established biotechnology innovation funds that support research projects focused on organ-on-chip applications. This financial backing is likely to stimulate innovation and collaboration among academic institutions and private companies. As a result, the organ-on-chip market is expected to expand, with increased investment leading to advancements in technology and applications. The proactive stance of governments in fostering biotechnological advancements could significantly enhance the growth prospects of the organ-on-chip sector.

Growing Demand for Personalized Medicine

The organ on-chip market in South America is experiencing a surge in demand for personalized medicine. This trend is driven by the increasing recognition of the need for tailored therapeutic approaches that consider individual genetic and phenotypic variations. As healthcare providers and researchers seek to develop more effective treatments, organ-on-chip technologies offer a promising solution by enabling the simulation of human organ responses to various drugs. The market for personalized medicine is projected to reach approximately $2.5 billion by 2026 in South America, indicating a robust growth trajectory. This demand is likely to propel advancements in organ-on-chip technologies, as they provide critical insights into drug efficacy and safety, thereby enhancing the overall drug development process.

Advancements in Microfabrication Techniques

Recent advancements in microfabrication techniques are significantly influencing the organ on-chip market in South America. Innovations in materials science and engineering have led to the development of more sophisticated and reliable organ-on-chip models. These advancements allow for the creation of more complex tissue structures that closely mimic human physiology. As a result, researchers can conduct more accurate drug testing and disease modeling. The market for microfabrication technologies is expected to grow at a CAGR of around 15% over the next five years, which will likely benefit the organ-on-chip sector. Enhanced microfabrication capabilities not only improve the functionality of organ-on-chip devices but also reduce production costs, making them more accessible to research institutions and pharmaceutical companies.

Rising Awareness of Ethical Research Practices

The organ on-chip market in South America is witnessing a rise in awareness regarding ethical research practices. As researchers and institutions strive to minimize the use of animal testing, organ-on-chip technologies present an ethical alternative that aligns with the principles of the 3Rs: Replacement, Reduction, and Refinement. This shift towards more humane research methodologies is likely to encourage the adoption of organ-on-chip systems in academic and industrial settings. Furthermore, regulatory bodies are increasingly advocating for the use of alternative testing methods, which may further bolster the market. The ethical implications of organ-on-chip technologies could lead to a broader acceptance and integration into research protocols, thereby enhancing their market presence.

Increasing Focus on Drug Development Efficiency

The organ on-chip market in South America is being propelled by an increasing focus on drug development efficiency. Pharmaceutical companies are under pressure to reduce the time and costs associated with bringing new drugs to market. Organ-on-chip technologies provide a platform for high-throughput screening and predictive modeling, which can significantly streamline the drug discovery process. By utilizing these technologies, companies can potentially reduce the time to market by up to 30%, thereby enhancing their competitive edge. The growing need for efficient drug development processes is expected to drive investments in organ-on-chip technologies, as they offer a viable solution to the challenges faced in traditional drug testing methods.

Market Segment Insights

By Organ Type: Lung-on-Chip (Largest) vs. Kidney-on-Chip (Fastest-Growing)

In the South America organ on-chip market, the distribution of market share is significantly tilted towards Lung-on-Chip technology, which has established itself as the largest segment due to its critical applications in respiratory research and drug testing. Following closely are Liver-on-Chip and Heart-on-Chip segments, which are gaining traction as they contribute valuable insights for related medical fields. Other segments, such as Kidney-on-Chip and Intestine-on-Chip, although smaller, are increasingly recognized for their innovative applications in nephrology and gastrointestinal studies. Growth trends in the South America organ on-chip market indicate a robust rise in research and development investments, particularly in the Kidney-on-Chip segment, which is currently marked as the fastest-growing. This growth is driven by the increasing need for personalized medicine and the demand for more reliable drug testing methods. Additionally, awareness of the benefits of organ-on-chip technology over traditional models encourages adoption across various sectors, further propelling the overall market forward.

Lung-on-Chip (Dominant) vs. Kidney-on-Chip (Emerging)

The Lung-on-Chip segment is characterized by its dominance in the South America organ on-chip market, primarily due to its advanced capabilities in simulating human lung responses under various physiological conditions. This technology plays a critical role in respiratory disease research and has become instrumental for pharmaceutical companies in drug development. Conversely, the Kidney-on-Chip segment is emerging rapidly as research intensifies in renal disease treatment and therapy responses. It offers an innovative approach to nephrology by mimicking kidney functions, showcasing an increasing demand for customized organ modeling. As research tools, both segment values offer unique advantages that contribute to improving the overall understanding of organ-specific diseases.

By Application: Drug Discovery (Largest) vs. Toxicology Research (Fastest-Growing)

In the Application segment, Drug Discovery commands a significant share of the market, underpinned by its critical role in developing new therapeutic treatments. This segment utilizes organ on-chip technologies to simulate human organs, facilitating a more efficient and cost-effective approach to drug testing. On the other hand, Toxicology Research is rapidly gaining traction, leveraging advancements in organ-on-chip platforms to offer innovative solutions for assessing drug safety and environmental impact, making it a key area of growth within the sector. The growth of both Drug Discovery and Toxicology Research is driven by the increasing demand for personalized medicine and the need for more accurate preclinical testing methods. Factors such as regulatory pressures for safer pharmaceuticals and the rise of Biotech firms venturing into organ-on-chip technologies are propelling the Toxicology Research segment. Furthermore, collaborations between research organizations and technology developers enhance the capacity for innovation, with Toxicology Research being positioned to become a fundamental aspect of pharmaceutical development processes.

Drug Discovery (Dominant) vs. Toxicology Research (Emerging)

Drug Discovery has emerged as the dominant force within the Application segment due to its extensive application in therapeutic advancements and clinical trials. It effectively streamlines the evaluation process by integrating human physiology into experimental designs, thereby reducing dependency on traditional animal testing. Conversely, Toxicology Research is classified as an emerging segment, rapidly evolving to address the critical need for efficient safety evaluations in drug development. It focuses on understanding the adverse effects of chemical compounds using organ-on-chip systems, which simulate real human biological responses. Both segments exhibit unique characteristics: while Drug Discovery is characterized by established methodologies and significant market investments, Toxicology Research is distinguished by its innovative approaches, appealing to an increasing number of stakeholders seeking cutting-edge solutions in drug safety assessments.

By End-User: Pharmaceutical Companies (Largest) vs. Research Organizations (Fastest-Growing)

In the South America organ on-chip market, pharmaceutical companies hold the largest share, dominating the landscape due to their significant investment in advanced drug development and testing methodologies. They utilize organ-on-chip technologies to enhance the efficiency of drug testing processes, reducing the time and cost associated with bringing new drugs to market. Meanwhile, research organizations are gaining traction, reflecting a growing demand for innovative research techniques that improve understanding of human biology and disease mechanisms. The growth of the end-user segment is driven by an increasing need for personalized medicine and the demand for more accurate preclinical testing models. Pharmaceutical companies benefit from the proven efficacy of organ-on-chip systems in drug discovery, while research organizations are rapidly adopting these technologies to enhance their experimental capabilities. This trend signifies a shift towards more efficient methodologies that are likely to sustain growth in both segments in the coming years.

Pharmaceutical Companies (Dominant) vs. Research Organizations (Emerging)

Pharmaceutical companies are characterized by their robust infrastructure and established pipelines for drug development, leveraging organ-on-chip solutions to streamline experiments and enhance predictive accuracy. These companies are deeply integrated into the healthcare landscape, benefiting from partnerships with regulatory bodies and academic institutions. In contrast, research organizations represent an emerging segment that is increasingly adopting organ-on-chip technologies to drive innovative studies in areas like toxicology and disease modeling. They focus on translational research, bridging the gap between basic science and clinical application, and their adaptive nature allows them to quickly implement new technologies and methodologies. Together, these segments reflect a dynamic interplay of established practices and innovative research in the South America organ on-chip market.

Get more detailed insights about South America Organ On Chip Market

Regional Insights

Brazil : Innovation and Investment Drive Growth

Brazil holds a dominant 15.0% market share in the organ-on-chip sector, valued at approximately $150 million. Key growth drivers include increasing investment in biotechnology and a rising demand for personalized medicine. Regulatory support from the Brazilian Health Regulatory Agency (ANVISA) has fostered innovation, while infrastructure improvements in research facilities enhance production capabilities. The growing trend towards in vitro testing is reshaping consumption patterns, aligning with global shifts towards sustainable practices.

Mexico : Regulatory Support Fuels Development

Mexico captures a 7.5% share of the organ-on-chip market, valued at around $75 million. The growth is driven by government initiatives aimed at boosting the biotech sector, including funding for research and development. Demand for organ-on-chip technologies is rising, particularly in pharmaceutical testing and toxicology. The Mexican government is actively promoting partnerships between academia and industry, enhancing the local ecosystem for innovation and commercialization.

Argentina : Research Institutions Lead Innovation

Argentina holds a 5.0% market share in the organ-on-chip sector, valued at approximately $50 million. The market is driven by a strong emphasis on research and development, particularly in universities and research institutions. Demand for organ-on-chip technologies is growing in drug discovery and disease modeling. Government policies supporting scientific research and international collaborations are crucial for market expansion, alongside investments in infrastructure to support biotech startups.

Rest of South America : Regional Collaboration Enhances Growth

The Rest of South America accounts for a 5.35% share of the organ-on-chip market, valued at about $53.5 million. Growth is fueled by increasing collaboration among countries in the region, focusing on shared research initiatives and technology transfer. Demand is particularly strong in countries like Chile and Colombia, where regulatory frameworks are evolving to support biotech innovations. Local players are emerging, but competition remains limited compared to larger markets like Brazil and Mexico.

South America Organ On Chip Market Regional Image

Key Players and Competitive Insights

The organ on-chip market in South America is characterized by a dynamic competitive landscape, driven by advancements in biotechnology and increasing demand for personalized medicine. Key players such as Emulate (US), TissUse (DE), and Mimetas (NL) are at the forefront, each adopting distinct strategies to enhance their market presence. Emulate (US) focuses on innovation through the development of advanced organ-on-chip platforms that mimic human physiology, thereby attracting partnerships with pharmaceutical companies for drug testing. TissUse (DE) emphasizes regional expansion, having recently established collaborations with local universities to foster research and development, which enhances its operational capabilities. Mimetas (NL) is leveraging digital transformation by integrating AI into its organ-on-chip systems, which allows for more precise modeling of human responses to drugs, thus shaping the competitive environment towards a more technology-driven approach.

In terms of business tactics, companies are increasingly localizing manufacturing to reduce costs and improve supply chain efficiency. The market structure appears moderately fragmented, with several players vying for dominance. However, the collective influence of major companies is significant, as they drive innovation and set industry standards. This competitive structure fosters an environment where collaboration and strategic partnerships are essential for growth and sustainability.

In October 2025, Emulate (US) announced a strategic partnership with a leading South American pharmaceutical firm to enhance drug development processes using its organ-on-chip technology. This collaboration is expected to streamline clinical trials and reduce time-to-market for new therapies, indicating a shift towards more localized solutions in drug testing. The strategic importance of this partnership lies in its potential to significantly impact the efficiency of drug development in the region, aligning with the growing trend of personalized medicine.

In September 2025, TissUse (DE) launched a new organ-on-chip model specifically designed for metabolic studies, which has garnered attention from research institutions across South America. This innovation not only strengthens TissUse's product portfolio but also positions the company as a leader in metabolic research applications. The introduction of this model reflects the increasing demand for specialized organ-on-chip solutions that cater to specific research needs, thereby enhancing TissUse's competitive edge.

In August 2025, Mimetas (NL) secured a funding round aimed at expanding its AI capabilities within its organ-on-chip platforms. This investment is likely to accelerate the development of more sophisticated models that can predict human responses with greater accuracy. The strategic importance of this funding lies in its potential to enhance Mimetas's market position by offering cutting-edge technology that meets the evolving demands of pharmaceutical research.

As of November 2025, current competitive trends in the organ on-chip market include a strong emphasis on digitalization, sustainability, and the integration of AI technologies. Strategic alliances are increasingly shaping the landscape, as companies recognize the value of collaboration in driving innovation. Looking ahead, competitive differentiation is expected to evolve, with a notable shift from price-based competition to a focus on technological advancements, innovation, and supply chain reliability. This transition underscores the importance of developing robust, reliable solutions that meet the complex needs of the market.

Key Companies in the South America Organ On Chip Market market include

Industry Developments

The South America Organ-On-Chip Market has seen significant developments recently, highlighting the continued growth and innovation in this sector. The demand for advanced drug testing systems and personalized medicine is increasing, with companies like Blacktrace, Mimetas, and TissUse focusing on developing sophisticated organ models to better mimic human physiology. In August 2023, Axiogenesis announced a partnership with a major Brazilian research institution, enhancing their research capabilities within South America. Additionally, Insphero launched a new line of organ-on-chip products tailored for local markets in September 2023, signaling a commitment to fulfilling regional needs. 

Moreover, a notable acquisition occurred when Kereos acquired technology from a local startup in May 2023, aimed at improving their organ-on-chip platforms, strengthening their foothold in the region. The South American market has also experienced increased funding, with Biolamina and Aurelia Bioscience securing investments to expand their operations, thereby impacting the overall market valuation positively. In recent years, a growing interest in organ-on-chip technology, especially for its applications in toxicology and pharmaceuticals, has driven the market's valuation to exceed several million dollars, positioning it as a key area of investment and research.

Future Outlook

South America Organ On Chip Market Future Outlook

The organ on-chip market is projected to grow at 3.72% CAGR from 2024 to 2035, driven by advancements in biotechnology, regulatory support, and increasing demand for personalized medicine.

New opportunities lie in:

  • Development of customized organ-on-chip platforms for drug testing
  • Partnerships with pharmaceutical companies for integrated research solutions
  • Expansion into educational institutions for research and training programs

By 2035, the organ on-chip market is expected to achieve substantial growth and innovation.

Market Segmentation

South America Organ On Chip Market End-User Outlook

  • Pharmaceutical Companies
  • Research Organizations
  • Others

South America Organ On Chip Market Organ Type Outlook

  • Lung-on-Chip
  • Heart-on-Chip
  • Liver-on-Chip
  • Intestine-on-Chip
  • Kidney-on-Chip
  • Skin-on-Chip
  • Blood-Brain Barrier-on-Chip
  • Human-on-Chip

South America Organ On Chip Market Application Outlook

  • Drug Discovery
  • Toxicology Research
  • Others

Report Scope

MARKET SIZE 202432.85(USD Million)
MARKET SIZE 202534.08(USD Million)
MARKET SIZE 203549.1(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)3.72% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["Emulate (US)", "TissUse (DE)", "Mimetas (NL)", "Organovo (US)", "Synlogic (US)", "Hesperos (US)", "InSphero (CH)", "Reinnervate (GB)", "Tissot (FR)"]
Segments CoveredOrgan Type, Application, End-User
Key Market OpportunitiesGrowing demand for personalized medicine drives innovation in the organ on-chip market.
Key Market DynamicsRising investment in Research and Development drives innovation in organ on-chip technologies across South America.
Countries CoveredBrazil, Mexico, Argentina, Rest of South America

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FAQs

What is the expected market size of the South America Organ-On-Chip Market in 2024?

The South America Organ-On-Chip Market is expected to be valued at 7.52 million USD in 2024.

What will be the market value of the South America Organ-On-Chip Market in 2035?

By 2035, the market is anticipated to reach a value of 32.05 million USD.

What is the expected compound annual growth rate (CAGR) for the South America Organ-On-Chip Market from 2025 to 2035?

The market is expected to grow at a CAGR of 14.083% from 2025 to 2035.

Which region holds the largest market share in the South America Organ-On-Chip Market?

Brazil is expected to hold the largest market share, valued at 2.5 million USD in 2024.

What are key players in the South America Organ-On-Chip Market?

Major players include Blacktrace, Mimetas, Axiogenesis, Biolamina, TissUse, and Emulate among others.

How much is the Lung-on-Chip segment valued in 2024 and 2035?

The Lung-on-Chip segment is valued at 1.5 million USD in 2024 and is projected to reach 6.39 million USD in 2035.

What market growth is expected for the Kidney-on-Chip segment by 2035?

The Kidney-on-Chip segment is expected to grow from 1.0 million USD in 2024 to 4.14 million USD in 2035.

What is the market value forecast for the Intestine-on-Chip segment in 2035?

The Intestine-on-Chip segment is projected to reach 7.33 million USD by 2035.

What opportunities exist in the South America Organ-On-Chip Market?

There are significant opportunities for growth due to advancements in personalized medicine and drug testing applications.

How does the market value for Argentina's Organ-On-Chip segment compare in 2024 and 2035?

Argentina's market for Organ-On-Chip is valued at 1.2 million USD in 2024 and is expected to grow to 5.1 million USD by 2035.

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