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    US Single Use Bioprocessing Market

    ID: MRFR/HC/13150-HCR
    100 Pages
    Rahul Gotadki
    October 2025

    US Single-Use Bioprocessing Market Research Report By Product (Filtration Assemblies, Disposable Bioreactors, Disposable Mixers, Media Bags and Containers, Others), By Application (Filtration, Purification, Cell Culture, Others), By End-User (Biopharmaceutical Manufacturers, Clinical & Academic Research Institutes, Others) and By Workflow (Upstream, Fermentation, Downstream) - Forecast to 2035

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    US Single Use Bioprocessing Market Infographic
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    US Single Use Bioprocessing Market Summary

    The US Single-Use Bioprocessing market is projected to grow from 4.19 USD Billion in 2024 to 9.1 USD Billion by 2035, indicating robust expansion.

    Key Market Trends & Highlights

    US Single-Use Bioprocessing Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate of 7.31 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 9.1 USD Billion, reflecting significant growth potential.
    • In 2024, the market is valued at 4.19 USD Billion, highlighting a strong starting point for future expansion.
    • Growing adoption of single-use technologies due to their cost-effectiveness is a major market driver.

    Market Size & Forecast

    2024 Market Size 4.19 (USD Billion)
    2035 Market Size 9.1 (USD Billion)
    CAGR (2025-2035) 7.31%

    Major Players

    Danaher Corporation, Lonza Group, GE Healthcare, Abcam plc, Baxter International, Thermo Fisher Scientific, Fujifilm Diosynth Biotechnologies, Repligen Corporation, Waters Corporation, Sartorius AG, 3M Company, Pall Corporation, Celtic Therapeutics, Merck KGaA, Eppendorf AG

    US Single Use Bioprocessing Market Trends

    The US Single-Use Bioprocessing Market is significantly influenced by several key market drivers. The increasing demand for biopharmaceuticals has fueled the need for efficient production methods, making single-use technologies attractive due to their flexibility and reduced operational costs. The US government has been supportive of bioprocess innovation, promoting initiatives that encourage the adoption of advanced manufacturing technologies. This has led to a surge in investments and research dedicated to enhancing single-use systems and addressing regulatory requirements.

    Moreover, the ongoing shift towards personalized medicine in the US further drives the demand for single-use bioprocessing, as these systems are more adaptable to smaller-scale production runs.In recent times, there are numerous opportunities to be explored within the US Single-Use Bioprocessing Market. Companies are focusing on integrating digital technologies and automation to further optimize single-use processes. The growing interest in cell and gene therapies in the US presents a lucrative opportunity, as single-use systems can provide the desired flexibility for the production of these complex therapies.

    The emergence of collaboration between biopharma companies and technology providers can also result in innovative solutions that enhance efficiency and safety in production. Trends in the US market reflect an increasing emphasis on sustainability and reducing environmental impact.Manufacturers are actively seeking eco-friendly materials for single-use products, aligning with the broader environmental goals set forth by federal and state regulations. Additionally, there is a rising trend towards the use of modular and hybrid systems, which allow for greater scalability.

    This evolution in the market indicates a move towards a more integrated and user-centered approach in bioprocessing, ensuring that the US maintains its leadership in biopharmaceutical production innovation.

    Market Segment Insights

    Single-Use Bioprocessing Market Product Insights

    The US Single-Use Bioprocessing Market reflects a significant shift towards more efficient, flexible, and cost-effective biomanufacturing solutions. With innovations driving the development of single-use technologies, the market features various key products that serve essential roles in bioprocessing applications. Filtration Assemblies play a crucial role in maintaining product integrity and ensuring sterility during bioprocessing, significantly impacting yield and quality.

    Disposable Bioreactors represent a prominent trend in the industry, as they facilitate bioproduction without the need for extensive cleaning and validation, thereby enhancing operational efficiency.Alongside these, Disposable Mixers are gaining traction due to their ability to ensure homogeneity in fluid mixing processes, a critical aspect in upstream and downstream processing. Media Bags and Containers serve as vital components for storing and transporting cell culture media and other solutions, underscoring the demand for containers that minimize contamination risks while ensuring easy accessibility.

    The diverse applications of these products showcase their importance in the bioprocessing landscape, often catering to the growing needs of the pharmaceutical and biotechnology sectors.As the US Single-Use Bioprocessing Market continues to expand, these products are expected to adapt to meet stringent regulatory requirements and achieve operational excellence, thereby capturing a critical portion of the market share in years to come. Overall, the segmentation of products plays a pivotal role in supporting the flexibility and scalability that modern bioprocessing requires, ultimately driving innovation and growth within the industry.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Single-Use Bioprocessing Market Application Insights

    The Application segment of the US Single-Use Bioprocessing Market plays a pivotal role in addressing the growing demands of the biopharmaceutical industry. This segment encompasses various functionalities including Filtration, Purification, Cell Culture, and others, each contributing uniquely to the bioprocessing landscape. Filtration processes significantly enhance product safety and quality in the manufacturing of biopharmaceuticals, while Purification techniques are crucial for isolating and refining biologics, thus ensuring the efficacy of therapeutic agents.

    Cell Culture applications are vital as they support the production of vaccines and monoclonal antibodies, reflecting a robust demand triggered by advancements in personalized medicine and biologic therapies. Additionally, other applications continue to innovate, catering to specific customer requirements, driven by technological advancements and regulatory changes. The increasing adoption of single-use technologies, coupled with the need for cost-effective and efficient biomanufacturing solutions, underscores the growth potential within the US Single-Use Bioprocessing Market.

    Overall, the dynamics within this segment highlight a progressive trend towards scalable and adaptable bioprocessing methodologies, aligning with the industry's direction towards sustainability and enhanced productivity.

    Single-Use Bioprocessing Market End-User Insights

    The End-User segment of the US Single-Use Bioprocessing Market plays a crucial role in driving the industry forward, with Biopharmaceutical Manufacturers being a dominant force due to their extensive reliance on efficient and cost-effective bioprocessing solutions. These manufacturers increasingly adopt single-use technologies to streamline production processes, minimize contamination risks, and reduce overall operational costs. Clinical and Academic Research Institutes also significantly contribute to market dynamics, utilizing innovative bioprocessing techniques as they pursue groundbreaking research and drug development initiatives.

    The demand for flexibility and scalability in manufacturing processes leads to an emphasis on single-use systems, allowing these institutions to operate with enhanced efficiency and reduced turnaround times. Additionally, a range of other users, spanning various sectors, further enriches the market landscape by diversifying applications and fostering innovation within the industry. This increased variety enhances the overall adaptability and responsiveness of the US Single-Use Bioprocessing Market as it evolves to meet the specific needs of different End-User groups.

    As these users continue to prioritize advancements in bioprocessing, the market is expected to witness sustained growth, reflecting a broader trend toward modernization and technological adoption across the biopharmaceutical space.

    Single-Use Bioprocessing Market Workflow Insights

    The US Single-Use Bioprocessing Market, particularly the Workflow segment, is experiencing noteworthy growth driven by various technological advancements and increasing demand for biologics. The Workflow segment encompasses essential processes such as Upstream, Fermentation, and Downstream, each playing a vital role in bioprocessing efficiency. Upstream processes focus on cell culture and the initial stages of production, ensuring high cellular yield, which is critical for the efficacy of biologics. Fermentation, a crucial element, transforms substrates into desired products, highlighting its importance in meeting the rising demand for therapeutics.

    Downstream processes emphasize the purification and formulation of products, ensuring quality and compliance with regulatory standards, which is significant in the highly regulated US market. The trend toward automation and integration within the Workflow segment is enhancing productivity and reducing operational costs. There's also a growing emphasis on sustainability and cost-efficiency, which drives the adoption of single-use technologies. As biopharmaceutical companies continuously seek innovative solutions to enhance their production capabilities, the Workflow segment stands out as a cornerstone of operational excellence within the US Single-Use Bioprocessing Market, offering substantial opportunities for growth and development.

    Get more detailed insights about US Single Use Bioprocessing Market Research Report - Forecast to 2035

    Key Players and Competitive Insights

    The US Single-Use Bioprocessing Market is characterized by dynamic competition among key players focusing on the development and advancement of bioprocessing technologies tailored for the biopharmaceutical industry. The competitive landscape features a mix of established global corporations and emerging companies that aim to enhance operational efficiency, reduce contamination risks, and provide flexible solutions for pharmaceutical manufacturing. This market has seen significant growth due to an increased demand for biologics, advanced therapies, and streamlined production processes.

    As a result, companies are investing in innovation, forming strategic partnerships, and expanding their product portfolios to gain a competitive edge in this rapidly evolving environment. Market leaders are continuously seeking ways to enhance their offerings and drive operational excellence, which is shaping the future of bioprocessing technology in the United States.

    Danaher Corporation holds a significant position in the US Single-Use Bioprocessing Market, where it leverages its diverse portfolio of technologies to provide robust bioprocessing solutions. The company's strengths lie in its commitment to innovation, quality assurance, and customer support, allowing it to meet the stringent demands of the biopharmaceutical sector. Danaher’s extensive range of single-use products is designed to enhance efficiency and minimize the risks associated with traditional bioprocessing methods. The company's clear focus on R&D continues to yield advanced solutions that are central to the production of monoclonal antibodies and other biologics.

    Danaher Corporation also enjoys a strong market presence owing to its reputation for reliability and excellence, facilitating partnerships with key industry stakeholders and fostering a collaborative approach to bioprocessing challenges.

    Lonza Group is another prominent player in the US Single-Use Bioprocessing Market, with a well-established reputation for its high-quality contract manufacturing services and product offerings. The company provides a comprehensive range of single-use bioprocessing solutions, including bioreactors, cell culture bags, and filtration devices. Lonza's strengths lie in its extensive experience, innovative product line, and commitment to enhancing bioprocessing efficiency for its clients. The company has engaged in significant mergers and acquisitions to expand its capabilities and strengthen its position in the market.

    Through these strategic movements, Lonza has broadened its service offering, making it a preferred choice for companies seeking reliable biopharmaceutical manufacturing solutions. By integrating advanced technologies and maintaining high-quality standards, Lonza Group effectively addresses the evolving needs of the bioprocessing landscape in the United States, thereby maintaining a forward-thinking approach in this competitive sector.

    Key Companies in the US Single Use Bioprocessing Market market include

    Industry Developments

    In the US Single-Use Bioprocessing Market, recent developments have showcased significant growth and investment activities. Leading companies like Danaher Corporation and Thermo Fisher Scientific have expanded their product portfolios and enhanced their manufacturing capabilities to meet the growing demand for single-use technologies in bioprocessing. Particularly in August 2023, AbbVie announced the establishment of a new facility focusing on single-use systems, signaling a strong commitment to advancing bioprocessing technologies.

    Additionally, Merck KGaA has invested heavily in research to optimize the use of single-use bioreactors, reinforcing its position in the market. Notable merger activities include Baxter International's acquisition of a bioprocessing company in July 2023, aimed at consolidating its presence in the single-use segment. The market valuation for companies like Repligen Corporation has seen a significant increase due to heightened demand as regulators emphasize more flexible and efficient manufacturing methods. Eppendorf AG reported substantial revenue growth in recent quarters, reflecting the robust market dynamics.

    The push towards sustainable practices, such as recycling single-use components, is also shaping industry trends as companies look to meet regulatory and environmental standards.

    Market Segmentation

    Single-Use Bioprocessing Market Product Outlook

    • Filtration Assemblies
    • Disposable Bioreactors
    • Disposable Mixers
    • Media Bags and Containers
    • Others

    Single-Use Bioprocessing Market End-User Outlook

    • Biopharmaceutical Manufacturers
    • Clinical & Academic Research Institutes
    • Others

    Single-Use Bioprocessing Market Workflow Outlook

    • Upstream
    • Fermentation
    • Downstream

    Single-Use Bioprocessing Market Application Outlook

    • Filtration
    • Purification
    • Cell Culture
    • Others

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2018 3.47(USD Billion)
    MARKET SIZE 2024 4.19(USD Billion)
    MARKET SIZE 2035 9.1(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 7.294% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED Danaher Corporation, Lonza Group, GE Healthcare, Abcam plc, Baxter International, Thermo Fisher Scientific, Fujifilm Diosynth Biotechnologies, Repligen Corporation, Waters Corporation, Sartorius AG, 3M Company, Pall Corporation, Celtic Therapeutics, Merck KGaA, Eppendorf AG
    SEGMENTS COVERED Product, Application, End-User, Workflow
    KEY MARKET OPPORTUNITIES Increased demand for biopharmaceuticals, Rising investments in biotechnology, Advancements in single-use technologies, Growing focus on cost efficiency, Expansion of contract manufacturing organizations
    KEY MARKET DYNAMICS growing demand for biologics, cost efficiency and flexibility, innovation in manufacturing technologies, regulatory compliance requirements, increased adoption of personalized medicine
    COUNTRIES COVERED US

    FAQs

    What is the expected market size of the US Single-Use Bioprocessing Market by 2024?

    The US Single-Use Bioprocessing Market is expected to be valued at approximately 4.19 billion USD in 2024.

    What will be the market value of the US Single-Use Bioprocessing Market by 2035?

    By 2035, the US Single-Use Bioprocessing Market is projected to reach around 9.1 billion USD.

    What is the expected CAGR for the US Single-Use Bioprocessing Market from 2025 to 2035?

    The expected CAGR for the US Single-Use Bioprocessing Market from 2025 to 2035 is approximately 7.294 percent.

    Which product segment will dominate the US Single-Use Bioprocessing Market by 2035?

    By 2035, the Filtration Assemblies product segment is expected to dominate with a projected value of 2.39 billion USD.

    What will be the market size for Disposable Bioreactors in 2024?

    The market size for Disposable Bioreactors in 2024 is valued at around 1.25 billion USD.

    What is the projected value of Disposable Mixers in the US Single-Use Bioprocessing Market by 2035?

    By 2035, the Disposable Mixers segment is projected to achieve a value of approximately 1.6 billion USD.

    Who are the key players in the US Single-Use Bioprocessing Market?

    Key players in the market include Danaher Corporation, Lonza Group, GE Healthcare, and Thermo Fisher Scientific among others.

    How much is the Media Bags and Containers segment expected to be valued at in 2024?

    The Media Bags and Containers segment is expected to be valued at around 0.85 billion USD in 2024.

    What are the growth drivers for the US Single-Use Bioprocessing Market?

    Growth drivers include increasing demand for biopharmaceuticals and the rising trend towards cost-effective bioproduction.

    What challenges does the US Single-Use Bioprocessing Market face?

    Challenges include potential regulatory hurdles and contamination risks associated with single-use systems.

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