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    Xerostomia Dry Mouth Disease Therapeutics Market

    ID: MRFR/HC/39237-HCR
    100 Pages
    Rahul Gotadki
    October 2025

    Xerostomia (Dry Mouth Disease) Therapeutics Market Research Report By Drug Class (Muscarinic Cholinergic Agonists, Sodium-Potassium ATPase Inhibitors, Mucin Mimetics, Salivary Gland Stimulants, Anti-Inflammatory Drugs, Other Drug Classes), By Route of Administration (Oral, Topical, Subcutaneous, Intravenous), By Indication (Xerostomia Associated with Head and Neck Radiation Therapy, Xerostomia Associated with Sjgren's Syndrome, Xerostomia Associated with Diabetes, Xerostomia Associated with Other Medical Conditions), By Distribution Chan...

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    Xerostomia Dry Mouth Disease Therapeutics Market Infographic
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    Xerostomia Dry Mouth Disease Therapeutics Market Summary

    The global Xerostomia therapeutics market is projected to grow from 3.27 USD billion in 2024 to 6.16 USD billion by 2035.

    Key Market Trends & Highlights

    Xerostomia (Dry Mouth Disease) Therapeutics Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 5.94 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 6.16 USD billion, reflecting robust growth.
    • In 2024, the market is valued at 3.27 USD billion, indicating a solid foundation for future expansion.
    • Growing adoption of innovative therapeutic solutions due to increasing awareness of xerostomia is a major market driver.

    Market Size & Forecast

    2024 Market Size 3.27 (USD Billion)
    2035 Market Size 6.16 (USD Billion)
    CAGR (2025-2035) 5.94%

    Major Players

    Biohaven Pharmaceuticals, Sun Pharmaceutical Industries, Rohto Pharmaceutical, Lion Corporation, Unilever, Colgate-Palmolive, Henkel, Reckitt Benckiser, Glaxo-Smith-Kline, Procter Gamble, Beiersdorf, Kao Corporation, Oral-B, L'Oréal, Bausch + Lomb, Johnson Johnson

    Xerostomia Dry Mouth Disease Therapeutics Market Trends

    The Xerostomia (Dry Mouth Disease) Therapeutics Market has several notable market trends. One of the major factors that continue to fuel the xerostomia market is the increase of xerostomia among aging populations and the higher incidence of chronic diseases. Besides, rising access to health care in developing countries and increasing consumer awareness of oral health also complement the growth. Moreover, advances in drug discovery, such as new treatment modalities for the treating causes of xerostomia, also allow the expansion of the economy.

    Recent trends include an emphasis on precision and individualized medicine, alongside the incorporation or enhancement of e-health technologies in the treatment of patients and management of diseases.

    The increasing prevalence of xerostomia among various populations underscores the urgent need for innovative therapeutic solutions to alleviate the discomfort associated with this condition.

    National Institute of Dental and Craniofacial Research

    Xerostomia Dry Mouth Disease Therapeutics Market Drivers

    Market Growth Projections

    The Global Xerostomia (Dry Mouth Disease) Therapeutics Market Industry is projected to experience substantial growth over the coming years. With an estimated market value of 3.27 USD Billion in 2024, the industry is poised for expansion, driven by various factors including increasing prevalence, advancements in treatment options, and rising awareness. The anticipated compound annual growth rate (CAGR) of 5.94% from 2025 to 2035 suggests a robust market trajectory. This growth is indicative of the ongoing need for effective therapeutic solutions to address the challenges posed by xerostomia, positioning the industry for a promising future.

    Rising Geriatric Population

    The global increase in the geriatric population is a significant factor driving the Global Xerostomia (Dry Mouth Disease) Therapeutics Market Industry. Older adults are more susceptible to xerostomia due to polypharmacy and age-related physiological changes. As the population aged 65 and older continues to grow, the demand for effective treatment options is expected to rise correspondingly. This demographic shift is likely to create a larger patient base, thereby enhancing market opportunities. The market's growth trajectory, with a valuation of 3.27 USD Billion in 2024, underscores the importance of addressing the needs of this vulnerable population.

    Growing Awareness and Education

    The increasing awareness and education surrounding xerostomia are pivotal in shaping the Global Xerostomia (Dry Mouth Disease) Therapeutics Market Industry. Healthcare providers are becoming more informed about the condition, leading to better diagnosis and treatment options. Public health campaigns aimed at educating patients about the symptoms and consequences of xerostomia are also gaining traction. This heightened awareness is likely to result in more individuals seeking therapeutic solutions, thus expanding the market. As the industry adapts to these changes, the anticipated compound annual growth rate (CAGR) of 5.94% from 2025 to 2035 indicates a robust future for therapeutic options.

    Advancements in Therapeutic Options

    Innovations in therapeutic options for xerostomia are significantly influencing the Global Xerostomia (Dry Mouth Disease) Therapeutics Market Industry. New formulations and delivery systems, such as oral sprays and lozenges, are being developed to enhance patient compliance and efficacy. For instance, the introduction of saliva substitutes and stimulants has shown promising results in clinical trials. These advancements not only improve the quality of life for patients but also drive market growth. As the industry evolves, it is anticipated that these innovations will contribute to an increase in market valuation, projected to reach 6.16 USD Billion by 2035.

    Increasing Prevalence of Xerostomia

    The rising incidence of xerostomia, or dry mouth disease, is a primary driver for the Global Xerostomia (Dry Mouth Disease) Therapeutics Market Industry. Factors such as aging populations and the prevalence of chronic diseases like diabetes contribute to this trend. As of 2024, the market is valued at approximately 3.27 USD Billion, reflecting the growing demand for effective therapeutic solutions. The increasing awareness among healthcare professionals and patients regarding the condition further fuels market growth. This heightened recognition is likely to lead to more patients seeking treatment options, thereby expanding the market's reach and potential.

    Impact of Chronic Conditions and Medications

    The prevalence of chronic conditions and the medications used to treat them are crucial drivers of the Global Xerostomia (Dry Mouth Disease) Therapeutics Market Industry. Conditions such as diabetes, hypertension, and autoimmune diseases often lead to xerostomia as a side effect of various medications. This correlation suggests a growing need for therapeutic interventions to manage dry mouth symptoms effectively. As healthcare providers recognize the link between these conditions and xerostomia, the demand for targeted treatments is likely to increase. This trend is expected to contribute to the market's growth, with projections indicating a market size of 6.16 USD Billion by 2035.

    Market Segment Insights

    Xerostomia (Dry Mouth Disease) Therapeutics Market Drug Class Insights  

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented based on drug class into Muscarinic Cholinergic Agonists, Sodium-Potassium ATPase Inhibitors, Mucin Mimetics, Salivary Gland Stimulants, Anti-Inflammatory Drugs, and Other Drug Classes. Muscarinic Cholinergic Agonists is one of the most important drug classes of the Xerostomia (Dry Mouth Disease) Therapeutics Market and held the largest market share in 2023.

    The effectiveness of drugs like pilocarpine and cevimeline in stimulating salivary glands to produce more saliva is the prime factor for the dominance of this drug class.Sodium-potassium ATPase Inhibitors are also gaining gradual importance in the market due to the ability of drugs like amifostine to protect salivary glands from radiation therapy. Mucin Mimetics, Salivary Gland Stimulants, and Anti-Inflammatory Drugs are other important drug classes of the Xerostomia (Dry Mouth Disease) Therapeutics Market. Each of these drug classes addresses the specific needs and preferences of patients being treated for xerostomia.

    The market for Other Drug Classes, which includes experimental drugs and therapeutics in the developmental stage, is expected to witness rapid growth in the near future.The growing research and development initiatives will only further expand the already growing therapeutic landscape of the Xerostomia (Dry Mouth Disease) Therapeutics Market. Overall, the market is expected to witness steady growth in the future.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Xerostomia (Dry Mouth Disease) Therapeutics Market Route of Administration Insights  

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented based on the Route of Administration as Oral, Topical, Subcutaneous, and Intravenous. In 2023, the Oral segment held the largest market share of 67.8% and is expected to exhibit dominant growth over the forecast period. This is because most of the xerostomia therapeutics are available in orally administered formulations, and these are convenient for drug delivery.

    The high patient acceptance and compliance of orally administered drugs, and the availability of various oral formulations are expected to boost the oral segment.The Topical segment is expected to experience the highest growth rates over the forecast period as topical agents are increasingly being used for the treatment of xerostomia. The Subcutaneous and Intravenous segments are expected to exhibit steady growth due to the emergence of several targeted therapies and a rise in the number of advances in drug delivery technologies.

    Xerostomia (Dry Mouth Disease) Therapeutics Market Indication Insights  

    The Xerostomia (Dry Mouth Disease) Therapeutics Market segmentation by Indication into Xerostomia Associated with Head and Neck Radiation Therapy, Xerostomia Associated with Sjogren's Syndrome, Xerostomia Associated with Diabetes, and Xerostomia Associated with Other Medical Conditions provides valuable insights into the specific applications and patient populations targeted by the market. Xerostomia Associated with the Head and Neck Radiation Therapy segment is expected to dominate the market due to the increasing incidence of head and neck cancers and the subsequent need for radiation therapy, which often leads to xerostomia as a side effect.

    Xerostomia Associated with Sjogren's Syndrome segment is also expected to contribute significantly to the overall market growth. Sjogren's Syndrome is an autoimmune disease that affects the salivary glands, resulting in reduced saliva production and xerostomia. The rising prevalence of Sjogren's Syndrome is expected to drive the growth of this segment. Xerostomia Associated with Diabetes segment is expected to have a steady growth rate, as diabetes can lead to decreased salivary flow and increased risk of xerostomia.

    The growing prevalence of diabetes worldwide is expected to contribute to the growth of this segment.Xerostomia Associated with Other Medical Conditions segment includes xerostomia caused by medications, aging, and other underlying medical conditions. This segment is expected to have a moderate growth rate, as the prevalence of these conditions varies across different regions and populations.

    Xerostomia (Dry Mouth Disease) Therapeutics Market Distribution Channel Insights  

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented into various distribution channels, including hospital pharmacies, retail pharmacies, online pharmacies, and clinics. Each channel plays a crucial role in the distribution of Xerostomia Dry Mouth Disease Therapeutics, catering to the specific needs of patients and healthcare professionals. Hospital pharmacies are a key distribution channel for Xerostomia Dry Mouth Disease Therapeutics, as they serve patients admitted to hospitals and provide medications directly to healthcare providers.

    The growth of the hospital pharmacy segment is driven by the increasing number of hospitalizations and the growing prevalence of chronic diseases, including Xerostomia and Dry Mouth Disease. Retail pharmacies are another important distribution channel for Xerostomia Dry Mouth Disease Therapeutics, offering convenience and accessibility to patients. The retail pharmacy segment is expected to experience significant growth due to the rising demand for over-the-counter medications and the increasing number of retail pharmacy chains. Online pharmacies are gaining popularity as a distribution channel for Xerostomia Dry Mouth Disease Therapeutics, providing patients with the convenience of ordering medications online.

    The growth of the online pharmacy segment is fueled by the increasing adoption of e-commerce and the growing preference for home delivery of medications. Clinics, including dental clinics and specialty clinics, also play a role in the distribution of Xerostomia Dry Mouth Disease Therapeutics. Clinics provide specialized care to patients and can offer personalized medication recommendations. The growth of the clinic segment is driven by the increasing demand for specialized healthcare services and the rising prevalence of chronic diseases.

    Xerostomia (Dry Mouth Disease) Therapeutics Market End User Insights  

    The End User segment of the Xerostomia (Dry Mouth Disease) Therapeutics Market is classified into Patients, Healthcare Professionals, Hospitals, Clinics, and Research Institutions. Among these, Patients hold the largest market share due to the increasing prevalence of xerostomia and the rising demand for effective treatments. For instance, according to a study published in the Journal of Oral and Maxillofacial Surgery, the global prevalence of xerostomia is estimated to be around 10%, which equates to approximately 700 million people worldwide.This high prevalence rate is expected to drive the growth of the Xerostomia (Dry Mouth Disease) Therapeutics Market.

    Additionally, rising awareness about xerostomia and its associated complications among patients is contributing to the increased demand for treatment options. This segment is expected to continue its dominance throughout the forecast period, with a projected market revenue of USD 2.5 billion by 2024.

    Get more detailed insights about Xerostomia (Dry Mouth Disease) Therapeutics Market Research Report – Global Forecast till 2032

    Regional Insights

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented into North America, Europe, APAC, South America, and MEA. North America holds the largest market share due to the high prevalence of xerostomia, the presence of key players, and favorable reimbursement policies. Europe follows North America due to the high awareness of oral health and the presence of a large geriatric population. APAC is expected to witness significant growth due to the rising incidence of xerostomia and the increasing adoption of advanced treatments.

    South America and MEA hold smaller market shares but are expected to grow steadily due to the increasing awareness of xerostomia and the growing healthcare infrastructure.

    Xerostomia (Dry Mouth Disease) Therapeutics Market Regional Insights  

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    In the Xerostomia (Dry Mouth Disease) Therapeutics Market, the leading players are continuously looking for a competitive edge through the introduction of innovative products and the expansion of their market coverage. The major Xerostomia (Dry Mouth Disease) Therapeutics Market players are specifically investing in the development of novel products, conducting clinical trials, and acquiring regulatory approvals. The Xerostomia (Dry Mouth Disease) Therapeutics Market development environment also experiences a high frequency of strategic collaborations, forming partnerships, and mergers and acquisitions as companies strive to improve their market capabilities and expand product offerings.

    One of the major performers in the Xerostomia (Dry Mouth Disease) Therapeutics Market is Biohaven Pharmaceuticals. This company is engaged in the development and commercialization of innovative therapies for neurological and rare diseases. The company has a significant clinical development pipeline of Xerostomia Dry Mouth Disease Therapeutics candidates. At the moment, troriluzole is the company's main candidate for the treatment of xerostomia. In particular, troriluzole is currently being evaluated in a Phase 3 trial for xerostomia treatment.

    Biohaven's commercial presence and focus on research and development make it one of the major players in the Xerostomia (Dry Mouth Disease) Therapeutics Market.

    Sun Pharmaceutical Industries is one of the major market participants and significant competitors in the Xerostomia (Dry Mouth Disease) Therapeutics Market. This company has a notable presence in the generics, branded generics, and specialty businesses and a wide variety of distribution channels, including a large presence in India and China. Sun Pharmaceutical Industries also has a notable commitment to innovation and the development of new Xerostomia Dry Mouth Disease Therapeutics.

    Key Companies in the Xerostomia Dry Mouth Disease Therapeutics Market market include

    Industry Developments

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is projected to reach USD 5.2 billion by 2032, at a CAGR of 5.8% from 2024 to 2032. The increasing prevalence of xerostomia, rising demand for effective treatments, and growing awareness of the condition are driving market growth.

    Key developments include: In 2023, Biohaven Pharmaceuticals announced positive results from a Phase 3 trial of its investigational drug, troriluzole, for the treatment of dry mouth. In 2024, Novartis launched a new dry mouth spray, Kraydel, which provides rapid and long-lasting relief. Several companies are developing novel therapies, such as gene therapies and stem cell therapies, to address the underlying causes of xerostomia.

    Future Outlook

    Xerostomia Dry Mouth Disease Therapeutics Market Future Outlook

    The Xerostomia Therapeutics Market is poised for growth at a 5.94% CAGR from 2024 to 2035, driven by increasing prevalence, innovative therapies, and rising awareness.

    New opportunities lie in:

    • Develop targeted therapies for specific xerostomia causes, enhancing treatment personalization.
    • Leverage telehealth platforms for remote patient monitoring and therapy management.
    • Invest in educational campaigns to raise awareness and improve patient access to treatments.

    By 2035, the Xerostomia Therapeutics Market is expected to achieve substantial growth, reflecting evolving patient needs and treatment advancements.

    Market Segmentation

    Xerostomia (Dry Mouth Disease) Therapeutics Market End User Outlook

    • Patients
    • Healthcare Professionals
    • Hospitals
    • Clinics
    • Research Institutions

    Xerostomia (Dry Mouth Disease) Therapeutics Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia-Pacific
    • Middle East and Africa

    Xerostomia (Dry Mouth Disease) Therapeutics Market Drug Class Outlook

    • Muscarinic Cholinergic Agonists
    • Sodium-Potassium ATPase Inhibitors
    • Mucin Mimetics
    • Salivary Gland Stimulants
    • Anti-Inflammatory Drugs
    • Other Drug Classes

    Xerostomia (Dry Mouth Disease) Therapeutics Market Indication Outlook

    • Xerostomia Associated with Head and Neck Radiation Therapy
    • Xerostomia Associated with Sjgren's Syndrome
    • Xerostomia Associated with Diabetes
    • Xerostomia Associated with Other Medical Conditions

    Xerostomia (Dry Mouth Disease) Therapeutics Market Distribution Channel Outlook

    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
    • Clinics

    Xerostomia (Dry Mouth Disease) Therapeutics Market Route of Administration Outlook

    • Oral
    • Topical
    • Subcutaneous
    • Intravenous

    Report Scope

    Report Attribute/Metric Details
    Market Size 2022 2.96(USD Billion)
    Market Size 2023 3.13(USD Billion)
    Market Size 2032 5.2(USD Billion)
    Compound Annual Growth Rate (CAGR) 5.8% (2024 - 2032)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2023
    Market Forecast Period 2024 - 2032
    Historical Data 2019 - 2022
    Market Forecast Units USD Billion
    Key Companies Profiled Rohto Pharmaceutical, Lion Corporation, Unilever, Colgate-Palmolive, Henkel, Reckitt Benckiser, Glaxo-Smith-Kline, Procter  Gamble, Beiersdorf, Kao Corporation, OralB, L'Oréal, Bausch + Lomb, Johnson  Johnson, P
    Segments Covered Drug Class, Route of Administration, Indication, Distribution Channel, End User, Regional
    Key Market Opportunities Growing awareness of unmet medical needs, technological advancements increasing the elderly population rising prevalence of cancer and autoimmune diseases
    Key Market Dynamics Increasing geriatric population, rising prevalence of diabetes, growing awareness of product innovation, government initiatives
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What is the expected market size of the Xerostomia (Dry Mouth Disease) Therapeutics Market in 2023?

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is expected to reach USD 3.13 billion in 2023.

    What is the expected market size of the Xerostomia (Dry Mouth Disease) Therapeutics Market in 2032?

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is expected to reach USD 5.2 billion in 2032.

    What is the expected CAGR of the Xerostomia (Dry Mouth Disease) Therapeutics Market from 2024 to 2032?

    The Xerostomia (Dry Mouth Disease) Therapeutics Market is expected to register a CAGR of 5.8% from 2024 to 2032.

    What are the key drivers of the Xerostomia (Dry Mouth Disease) Therapeutics Market?

    Key drivers of the Xerostomia (Dry Mouth Disease) Therapeutics Market include the increasing prevalence of dry mouth syndrome, supportive government initiatives, and the rising geriatric population.

    What are the key restraints of the Xerostomia (Dry Mouth Disease) Therapeutics Market?

    Key restraints of the Xerostomia (Dry Mouth Disease) Therapeutics Market include the side effects associated with certain treatments and the lack of awareness about the condition.

    What are the key opportunities in the Xerostomia (Dry Mouth Disease) Therapeutics Market?

    Key opportunities in the Xerostomia (Dry Mouth Disease) Therapeutics Market include the development of novel therapies and the increasing adoption of personalized medicine.

    What are the key challenges in the Xerostomia (Dry Mouth Disease) Therapeutics Market?

    Key challenges in the Xerostomia (Dry Mouth Disease) Therapeutics Market include the high cost of treatment and the limited reimbursement coverage.

    Who are the key competitors in the Xerostomia (Dry Mouth Disease) Therapeutics Market?

    Key competitors in the Xerostomia (Dry Mouth Disease) Therapeutics Market include GlaxoSmithKline, Novartis, and Pfizer.

    What are the key application segments in the Xerostomia (Dry Mouth Disease) Therapeutics Market?

    Key application segments in the Xerostomia (Dry Mouth Disease) Therapeutics Market include prescription drugs and over-the-counter products.

    What are the key regional markets for the Xerostomia (Dry Mouth Disease) Therapeutics Market?

    Key regional markets for the Xerostomia (Dry Mouth Disease) Therapeutics Market include North America, Europe, Asia-Pacific, and the Rest of the World.

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