Global market valuation was derived through revenue mapping and prescription volume analysis. The methodology included:
• Identification of 50+ key manufacturers across North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa
• Product mapping across PDE5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil), testosterone replacement therapies (injections, gels, patches), alprostadil (injectable and intraurethral suppositories), and vacuum erection devices
• Analysis of reported and modeled annual revenues specific to erectile dysfunction drug portfolios, including branded and generic segments
• Coverage of manufacturers representing 75-80% of global market share in 2024
• Extrapolation using bottom-up (prescription volume × ASP by country/region, adjusted for generic penetration rates) and top-down (manufacturer revenue validation, adjusted for pipeline product probability-weighted net present value) approaches to derive segment-specific valuations by drug class, route of administration, and distribution channel