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    Chromatography Reagents Market

    ID: MRFR/HC/7695-HCR
    150 Pages
    Kinjoll Dey
    October 2025

    Chromatography Reagents Market Research Report Information by Type (Solvents, Buffers, Derivatization Reagents, Ion-Pair Reagents), by Technology (Gas Chromatography {GC} Reagents, Liquid Chromatography {LC}Reagents, Supercritical Fluid Chromatography {SFC}Reagents, Thin Layer Chromatography {TLC}Reagents), by Separation Mechanism (Adsorption Chromatography, Partition Chromatography, Ion-Exchange Chromatography, Size-Exclusion Chromatography, Affinity Chromatography) and by Region (North America, Europe, Asia-Pacific, and Rest of the World)—...

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    Chromatography Reagents Market Infographic
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    Chromatography Reagents Market Summary

    The Global Chromatography Reagents Market is projected to grow significantly from 8.71 USD Billion in 2024 to 16.4 USD Billion by 2035.

    Key Market Trends & Highlights

    Chromatography Reagents Key Trends and Highlights

    • The market is expected to expand at a compound annual growth rate (CAGR) of 5.9% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 16.4 USD Billion, indicating robust growth potential.
    • In 2024, the market is valued at 8.71 USD Billion, reflecting a strong foundation for future expansion.
    • Growing adoption of chromatography techniques due to increasing demand for quality control in pharmaceuticals is a major market driver.

    Market Size & Forecast

    2024 Market Size 8.71 (USD Billion)
    2035 Market Size 16.4 (USD Billion)
    CAGR (2025-2035) 5.9%

    Major Players

    Agilent Technologies, Inc., Avantor, Bio-Rad Laboratories, Inc., Chiron AS, Cytiva, GFS Chemicals Inc, Kanto Chemical, Loba Chemie Pvt. Ltd, Merck KGaA, Regis Technologies, Inc., Restek, Santa Cruz Biotechnology, Spectrum Chemical Mfg. Corp., Thermo Fisher Scientific, Tosoh Bioscience, Waters Corporation

    Chromatography Reagents Market Drivers

    Market Growth Projections

    Growth in Biopharmaceuticals

    The biopharmaceutical sector significantly influences the Global Chromatography Reagents Market Industry, as the production of biologics requires sophisticated purification processes. Chromatography is essential for the separation and purification of proteins, antibodies, and other biomolecules. The increasing investment in biopharmaceutical research and development, coupled with the rising prevalence of chronic diseases, is expected to propel the market forward. This growth trajectory aligns with a projected CAGR of 5.9% from 2025 to 2035, indicating a robust demand for chromatography reagents tailored for biopharmaceutical applications.

    Rising Demand for Analytical Testing

    The Global Chromatography Reagents Market Industry experiences a surge in demand for analytical testing across various sectors, including pharmaceuticals, food and beverage, and environmental monitoring. This trend is driven by stringent regulatory requirements that necessitate accurate and reliable testing methods. For instance, the pharmaceutical sector relies heavily on chromatography for drug formulation and quality control. As a result, the market is projected to reach 8.71 USD Billion in 2024, reflecting the increasing need for high-quality reagents that ensure compliance with regulatory standards.

    Emerging Markets and Global Expansion

    Emerging markets present a significant opportunity for the Global Chromatography Reagents Market Industry as developing economies invest in healthcare and research infrastructure. Countries in Asia-Pacific and Latin America are witnessing rapid growth in laboratory facilities and analytical services, which drives the demand for chromatography reagents. As these regions enhance their research capabilities, the market is likely to experience substantial growth, contributing to the overall expansion of the industry. This trend underscores the importance of global outreach and the need for manufacturers to adapt their strategies to cater to diverse market needs.

    Environmental Regulations and Sustainability

    Environmental regulations are becoming increasingly stringent, driving the Global Chromatography Reagents Market Industry towards sustainable practices. Industries are compelled to adopt greener methodologies to comply with environmental standards, which often necessitate the use of chromatography for monitoring pollutants and ensuring product safety. The emphasis on sustainability is prompting manufacturers to develop eco-friendly reagents that minimize environmental impact. This shift not only aligns with regulatory compliance but also caters to the growing consumer demand for sustainable products, thereby enhancing market prospects.

    Technological Advancements in Chromatography

    Technological advancements play a pivotal role in shaping the Global Chromatography Reagents Market Industry. Innovations such as ultra-high-performance liquid chromatography (UHPLC) and advancements in mass spectrometry enhance the efficiency and accuracy of separation techniques. These developments not only improve the resolution of complex mixtures but also reduce analysis time, thereby increasing throughput in laboratories. As these technologies become more accessible, they are likely to drive market growth, contributing to an anticipated market value of 16.4 USD Billion by 2035, as laboratories seek to adopt cutting-edge methodologies.

    Key Companies in the Chromatography Reagents Market market include

    Industry Developments

      • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    Future Outlook

    Chromatography Reagents Market Future Outlook

    The Global Chromatography Reagents Market is projected to grow at a 5.9% CAGR from 2024 to 2035, driven by advancements in analytical techniques and increasing demand in pharmaceuticals.

    New opportunities lie in:

    • Develop eco-friendly chromatography reagents to meet sustainability goals.
    • Invest in automation technologies for enhanced laboratory efficiency.
    • Expand product offerings to include specialty reagents for niche applications.

    By 2035, the market is expected to reach a robust position, reflecting substantial growth and innovation.

    Market Segmentation

    By Type

    • Solvents
    • Buffers
    • Derivatization Reagents
    • Ion-Pair Reagents
    • Gas Chromatography Reagents
    • Liquid Chromatography Reagents
    • Supercritical Fluid Chromatography Reagents
    • Thin-Layer Chromatography Reagents
    • Adsorption Chromatography
    • Partition Chromatography
    • Ion-Exchange Chromatography
    • Size-Exclusion Chromatography
    • Affinity Chromatography
    • Pharmaceutical Testing
    • Biopharma-Biotech Applications
    • Research & Academic Applications
    • Food & Beverage Testing
    • Clinical Testing
    • Others
    • North America:
    • Europe:
    • Asia-Pacific:
    • Rest of the World:
    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    By Region

    • North America:
    • Europe:
    • Asia-Pacific:
    • Rest of the World:
    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    Key Players

    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    By Technology

    • Gas Chromatography Reagents
    • Liquid Chromatography Reagents
    • Supercritical Fluid Chromatography Reagents
    • Thin-Layer Chromatography Reagents
    • Adsorption Chromatography
    • Partition Chromatography
    • Ion-Exchange Chromatography
    • Size-Exclusion Chromatography
    • Affinity Chromatography
    • Pharmaceutical Testing
    • Biopharma-Biotech Applications
    • Research & Academic Applications
    • Food & Beverage Testing
    • Clinical Testing
    • Others
    • North America:
    • Europe:
    • Asia-Pacific:
    • Rest of the World:
    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    By Application

    • Pharmaceutical Testing
    • Biopharma-Biotech Applications
    • Research & Academic Applications
    • Food & Beverage Testing
    • Clinical Testing
    • Others
    • North America:
    • Europe:
    • Asia-Pacific:
    • Rest of the World:
    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    Recent Developments

    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    Competitive Landscape

    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    By Separation Mechanism 

    • Adsorption Chromatography
    • Partition Chromatography
    • Ion-Exchange Chromatography
    • Size-Exclusion Chromatography
    • Affinity Chromatography
    • Pharmaceutical Testing
    • Biopharma-Biotech Applications
    • Research & Academic Applications
    • Food & Beverage Testing
    • Clinical Testing
    • Others
    • North America:
    • Europe:
    • Asia-Pacific:
    • Rest of the World:
    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    Chromatography Reagents Market Drivers

    • Increasing number of awards, grants, scholarships, and funding for chromatography research
    • Rising applications of chromatography reagents for drug development in oncology
    • Therapeutic drug monitoring and dose adjustment of drugs are beneficial in treating various cancer. For example, a research paper published in 2020 in Therapeutic Drug Monitoring aimed to validate a high-performance liquid chromatography (HPLC) method for routine serum lenvatinib detection in patients with thyroid cancer.A high number of methods are being developed by researchers based on various chromatographic techniques increasing the demand for chromatography reagents
    • Similarly, a clinical study published in Biomedical Chromatography during 2020 assessed various bioanalytical methods used for immuno-oncology drugs in cancer therapy. The most commonly used methods according to this study were HPLC and Liquid Chromatography-Mass Spectrometry (LC-MS).A higher frequency of chromatography-based techniques for quantitative analysis of drugs used for cancer is expected to propel the chromatography reagents market growth. Moreover, an increasing number of cancer patients is expected to support this growth. National Cancer Institute estimated 1,806,590 new cases of cancer in the US for 2020, while an estimated 16.9 million cancer survivors in the US.

    Chromatography Reagents Market Segment

    • Solvents
    • Buffers
    • Derivatization Reagents
    • Ion-Pair Reagents
    • Gas Chromatography Reagents
    • Liquid Chromatography Reagents
    • Supercritical Fluid Chromatography Reagents
    • Thin-Layer Chromatography Reagents
    • Adsorption Chromatography
    • Partition Chromatography
    • Ion-Exchange Chromatography
    • Size-Exclusion Chromatography
    • Affinity Chromatography
    • Pharmaceutical Testing
    • Biopharma-Biotech Applications
    • Research & Academic Applications
    • Food & Beverage Testing
    • Clinical Testing
    • Others
    • North America:
    • Europe:
    • Asia-Pacific:
    • Rest of the World:
    • Waters Corporation (US)
    • Tosoh Bioscience (Japan)
    • Thermo Fisher Scientific (US)
    • Spectrum Chemical Mfg. Corp. (US)
    • Santa Cruz Biotechnology (US)
    • Restek (US)
    • Regis Technologies, Inc. (US)
    • Merck KGaA (Germany)
    • Loba Chemie Pvt. Ltd (India)
    • Kanto Chemical (Japan)
    • GFS Chemicals Inc (US)
    • Cytiva (US)
    • Chiron AS (Norway)
    • Bio-Rad Laboratories, Inc. (US)
    • Avantor (US)
    • Agilent Technologies, Inc. (US)
    • In 2019, CARLO ERBA Reagents (Italy), a producer of solvents for chromatography,extended its range of solvents for GC to meet the increasing demand from researchers for detection methods. CARLO ERBA Reagents offers a specific range of products dedicated to the GC-MS application with very high purity.

    Chromatography Reagents Market Restraints

    • Shortage of supplies and reagents
    • Helium is widely utilized as the carrier gas for gas chromatography. Its applications include deep-sea diving, airbags, cryogenics, rocket fuel, and MRI machines.It is the gold standard for gas chromatography as it is safe, inert, and provides optimal run times for gas chromatography. The helium shortage, which startedin 2019 globally, can impede the growth of the chromatography reagents market. Owing to this,severalgas chromatography professionals are switching to hydrogen gas using a hydrogen generator as their carrier gas supply.
    • The commonly used organic solvents for mobile phases in reverse chromatography are probably acetonitrile and methanol. The analytical industry experienceda severeacetonitrile shortage during the first half of 2020. Waters Corporation (US) has recommended replacing traditional high-performance HPLC with Waters ACQUITY UltraPerformance LC,which reduces acetonitrile consumption by at least 70%. The shortage of necessary supplies is anticipated to curb the growth of the chromatography reagents market.

    Chromatography Reagents Market Opportunities

    • Growing applications of chromatography
    • Value Chain Analysis

    Global Chromatography Reagents Market, by Type

    • Other
    • Ion-Pair Reagents
    • Derivatization Reagents
    • Buffers
    • Solvents

    Global Chromatography Reagents Market, by Region

    • Rest of the World
    • Middle East
    • Africa
    • Latin America
    • Asia-Pacific
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    • Europe
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    • North America
    • US
    • Canada

    Global Chromatography Reagents Market, by Technology

    • Others
    • Thin Layer Chromatography Reagents
    • Supercritical Fluid Chromatography Reagents
    • Liquid Chromatography Reagents
    • Gas Chromatography Reagents

    Global Chromatography Reagents Market, by Application

    • Others
    • Clinical Testing
    • Food & Beverage Testing
    • Research & Academic Applications
    • Biopharma-Biotech Applications
    • Pharmaceutical Testing

    Global Chromatography Reagents Market, by Separation Mechanism

    • Others
    • Affinity Chromatography
    • Size-Exclusion Chromatography
    • Ion-Exchange Chromatography
    • Partition Chromatography
    • Adsorption Chromatography

    Report Scope

    Report Attribute/Metric Details
      Market Size   2032: USD 13.7 Billion
      CAGR   6.1%
      Base Year   2020
      Forecast Period   2023-2032
      Historical Data   2018 & 2019
      Forecast Units   Value (USD Million)
      Report Coverage   Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
      Segments Covered   Type, Technology, Separation Mechanism, Application
      Geographies Covered   North America, Europe, AsNorth America, Europe, Asia-Pacific, Rest of the Worldia-Pacific, Rest of the World
      Key Vendors   • Agilent Technologies, Inc. (US) • Avantor (US) • Bio-Rad Laboratories, Inc. (US) • Chiron AS (Norway) • Cytiva (US) • GFS Chemicals Inc (US) • Kanto Chemical (Japan) • Loba Chemie Pvt. Ltd. (India) • Merck KGaA (Germany) • Regis Technologies, Inc. (US) • Restek (US) • Santa Cruz Biotechnology (US) • Spectrum Chemical Mfg. Corp. (US) • Thermo Fisher Scientific (US) • Tosoh Bioscience (Japan) • Waters Corporation (US)
      Key Market Opportunities   Development of cell banks in developing countries
      Key Market Drivers   • Growing utilization of chromatography in drug development • Rising number of strategic decisions by manufacturers

    Market Highlights

    Author
    Kinjoll Dey
    Research Analyst Level I

    He is an extremely curious individual currently working in Healthcare and Medical Devices Domain. Kinjoll is comfortably versed in data centric research backed by healthcare educational background. He leverages extensive data mining and analytics tools such as Primary and Secondary Research, Statistical Analysis, Machine Learning, Data Modelling. His key role also involves Technical Sales Support, Client Interaction and Project management within the Healthcare team. Lastly, he showcases extensive affinity towards learning new skills and remain fascinated in implementing them.

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