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    Oral Anticoagulants Market

    ID: MRFR/HC/6249-CR
    150 Pages
    Rahul Gotadki
    March 2019

    Oral Anticoagulants Market Research Report Information By Product (Novel Oral Anticoagulant and Warfarin), By Disease Indication (Atrial Fibrillation, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), and Heart Attacks), By Distribution Channel (Retail Pharmacies, Hospital Pharmacies, and Online Pharmacies), And By Region (Europe, Asia-Pacific, North America, And Rest Of The World) – Market Forecast Till 2035

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    Oral Anticoagulants Market Infographic
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    Oral Anticoagulants Market Summary

    The Global Oral Anticoagulants Market is projected to grow from 24.76 USD Billion in 2024 to 44.77 USD Billion by 2035.

    Key Market Trends & Highlights

    Global Oral Anticoagulants Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 5.53% from 2025 to 2032.
    • By 2035, the market valuation is anticipated to reach 44.8 USD Billion, reflecting robust growth.
    • in 2024, the market is valued at 24.76 USD Billion, indicating a strong foundation for future expansion.
    • Growing adoption of novel oral anticoagulants due to increasing prevalence of cardiovascular diseases is a major market driver.

    Market Size & Forecast

    2024 Market Size 24.76 (USD Billion)
    2035 Market Size 44.77 (USD Billion)
    CAGR (2025-2035) 5.53%

    Major Players

    AstraZeneca Plc, Pfizer, Boehringer Ingelheim GmbH, Daiichi Sankyo Company Ltd, Abbott Laboratories, Eli Lilly & Company, GlaxoSmithKline Plc, Portola Pharmaceuticals Inc, Medicure, Johnson & Johnson Services Inc

    Oral Anticoagulants Market Trends

    Increased blood thinners awareness and innovation to drive market growth

    Increased awareness about cardiovascular health, as well as the corresponding increase in new therapeutic launches, is one of the crucial drivers of  market growth. Cardiovascular therapeutics entails a multifaceted approach that may result in various medications. Nonetheless, blood thinners are an essential part of that treatment regimen. Several key market leaders have introduced anticoagulants, addressing the critical needs of treatment in terms of blood clot prevention. For instance, Pfizer Inc and Bristol-Myers Squibb Company introduced the anticoagulant Eliquis (apixaban). The product sells well and has shown superior risk reductions compared to other drugs, propelling the oral anticoagulants market CAGR.

    The high prevalence of cardiovascular diseases (CVD) worldwide and the increasing demand for suitable thinners are also important driving factors. Anticoagulants have undergone significant R&D advancements since they were first made available to the general public. Since then, several novel therapeutics have been introduced and have been incredibly successful, including novel oral anticoagulants (NOACs). Eliquis and Xarelto are now the two most important anticoagulants on the  market. A greater prevalence of generics and additionally anticipated launches of anticoagulant generics could hurt the market.

    However, the nature of cardiovascular diseases (CVD) has rendered them nearly incurable, and the rising prevalence is worsening patients' treatment options. This market, which has several unmet medical needs, is anticipated to be another critical growth driver for the  oral anticoagulants market revenue.

    The ongoing evolution of oral anticoagulants is reshaping therapeutic strategies, enhancing patient outcomes through improved safety profiles and convenience of administration.

    U.S. Food and Drug Administration (FDA)

    Oral Anticoagulants Market Drivers

    Market Growth Projections

    Rising Awareness and Education

    Enhanced awareness and education regarding the risks associated with thromboembolic events are driving the Global Oral Anticoagulants Market Industry. Public health campaigns and healthcare provider initiatives are effectively informing patients about the importance of anticoagulant therapy in preventing strokes and other complications. This increased awareness is likely to lead to higher patient engagement in treatment decisions, thereby boosting the demand for oral anticoagulants. As a result, the market is expected to grow steadily, with projections indicating a significant increase in market size as more individuals seek preventive measures against thromboembolic disorders.

    Increasing Geriatric Population

    The global increase in the geriatric population is a significant factor driving the Global Oral Anticoagulants Market Industry. Older adults are at a higher risk for thromboembolic disorders, necessitating effective anticoagulation therapies. As the demographic shifts towards an aging population, healthcare systems are adapting to meet the growing demand for anticoagulants. This trend is particularly pronounced in developed regions, where the elderly population is projected to expand substantially. Consequently, the market is poised for growth, with the potential for increased revenues as healthcare providers prioritize anticoagulant therapies for this vulnerable demographic.

    Advancements in Drug Development

    Innovations in drug development are significantly influencing the Global Oral Anticoagulants Market Industry. The introduction of novel oral anticoagulants (NOACs) has transformed treatment protocols, offering patients more effective and safer options compared to traditional anticoagulants. These advancements not only enhance patient compliance but also reduce the risk of adverse effects. As a result, the market is likely to experience a compound annual growth rate (CAGR) of 5.53% from 2025 to 2035. This growth is indicative of the pharmaceutical industry's commitment to research and development in anticoagulant therapies.

    Regulatory Support and Approvals

    Regulatory support and timely approvals for new anticoagulant therapies are crucial drivers of the Global Oral Anticoagulants Market Industry. Regulatory agencies are increasingly recognizing the need for innovative treatments that address unmet medical needs in anticoagulation. This supportive environment facilitates the introduction of new oral anticoagulants, which are often more effective and easier to manage than traditional therapies. As a result, the market is likely to benefit from a steady influx of new products, contributing to its growth trajectory and enhancing treatment options available to healthcare providers and patients.

    Rising Prevalence of Cardiovascular Diseases

    The increasing incidence of cardiovascular diseases globally is a primary driver of the Global Oral Anticoagulants Market Industry. As cardiovascular conditions such as atrial fibrillation and venous thromboembolism become more prevalent, the demand for effective anticoagulant therapies rises. In 2024, the market is projected to reach 24.8 USD Billion, reflecting the urgent need for innovative treatment options. This trend is expected to continue, with the market potentially expanding to 44.8 USD Billion by 2035, indicating a growing recognition of the importance of anticoagulants in managing cardiovascular health.

    Market Segment Insights

    Oral Anticoagulants Product Insights

    Based on product, the oral anticoagulants market segmentation includes novel oral anticoagulants and warfarin. The novel oral anticoagulant segment held the majority share in 2022, accounting for 65-67% of the  oral anticoagulants market revenue, owing to the increasing acceptance of novel oral anticoagulants (NOACs) in developing nations and the high preference for NOACs over warfarin. The term 'novel oral anticoagulants' (NOACs) refers to a new class of anticoagulant medications. Besides, they are safe (lower risk of major bleeding), easy to use, have no food interactions, and have a shorter half-life. The NOACs include drugs like apixaban, rivaroxaban, dabigatran, and edoxaban.

    These can prevent and treat pulmonary embolism, deep vein thrombosis (DVT), and atrial fibrillation/myocardial infarction. According to a June 2022 update from the Centers for Disease Control & Prevention (CDC), nearly 900,000 people ((1 to 2 per 1,000 population)) in the United States could be affected by deep vein thrombosis each year. Deep vein thrombosis also claims the lives of 60,000–100,000 Americans annually. Thus, the rising prevalence of cardiovascular diseases, venous thromboembolism (VTE), and technological advances in developing novel products are the main driving factors in the novel oral anticoagulants segment.

    Oral Anticoagulants Disease Indication Insights

    Based on disease indication, the  oral anticoagulants market segmentation includes atrial fibrillation, deep vein thrombosis (DVT), pulmonary embolism (PE), and heart attacks. The pulmonary embolism (PE) segment dominated the market in 2022 and is projected to be the faster-growing segment during the forecast period, 2022-2030. A blood clot that forms in the pulmonary arteries of the lungs and prevents blood flow is called a pulmonary embolism. This condition is potentially fatal and can lead to a more critical illness known as deep vein thrombosis (DVT).

    Another factor anticipated to fuel market growth is the rising prevalence of pulmonary embolism brought on by other risk factors like obesity, heart disease, and cancer.

    Figure 2 Oral Anticoagulants Market, by Disease Indication, 2022 & 2032 (USD Billion) 

    Source Primary Research, Secondary Research, Market Research Future Database, and Analyst Review

    Further, the heart attack segment is expected to grow the fastest in the oral anticoagulants industry during the forecast period since anticoagulants are essential for preventing additional myocardial infarctions in people who have already had one heart attack. Anticoagulant therapy is advised for people with atrial fibrillation and a high risk of stroke.

    Oral Anticoagulants Distribution Channel Insights

    Distribution channels have bifurcated the  oral anticoagulants market data into hospital pharmacies, retail pharmacies, and online pharmacies. The retail pharmacies segment led the  market in 2022 and is projected to be the faster-growing segment during the forecast period 2022-2030. Retail pharmacies can provide efficient services for prescription refilling.

    Aside from the retail pharmacies, the online pharmacies segment is expected to have the highest  oral anticoagulants industry growth in the forecast period due to an increase in the use of online pharmacy services by various nations. Online pharmacies are becoming increasingly popular owing to their ease and convenience. According to a recent Annals of Internal Medicine study, direct-acting oral anticoagulants (DOACs) are cheaper than heparin with low molecular weight (LMWH) injections for treating cancer-associated thrombosis. When deciding on the best course of action for these patients, policymakers and physicians should use the findings as a guide.

    Specific cancer-related pathways may be involved, even if some mechanisms may be shared with non-malignant conditions. According to a popular theory, cancer may activate platelets and the coagulation cascade. Additionally, cancer treatments may increase this risk—again, the underlying processes are unclear.

    Get more detailed insights about Oral Anticoagulants Market Research Report - Forecast till 2032

    Regional Insights

    By Region, the study provides market insights into Europe, North America, Asia-Pacific, and the Rest of the World. The North America Oral Anticoagulants market accounted for USD 9.57 billion in 2022 and is anticipated to exhibit a significant CAGR growth over the study period. The high prevalence of cardiovascular diseases requiring anticoagulant treatment, combined with new product launches throughout the region, will drive the growth of the oral anticoagulants market. According to American Heart Association research in October 2021, roughly 2,300 Americans die each day from cardiovascular diseases, an average of one death every 38 seconds.

    Additionally, the Centers for Disease Control & Prevention estimates that in February 2022, heart disease will be the leading cause of mortality in the United States, with about 659,000 deaths annually. This accounts for nearly 25% of all deaths in the United States. As a result of the rise in cardiovascular diseases, the demand for oral anticoagulants in the region is increasing, boosting the market.

    Along with these factors, the market in North America is anticipated to grow during the forecast period due to rising research and development efforts, increased awareness, and the prevalence of risk factors like obesity and diabetes among the general populace.

    Further, the major countries studied in the market report are the U.S., Germany, Canada, France, the UK, Italy, Japan, India, Australia, Spain, China, South Korea, and Brazil.

    Figure 3 ORAL ANTICOAGULANTS MARKET SHARE BY REGION 2022 (%)Oral Anticoagulants Market

    Source Primary Research, Secondary Research, Market Research Future Database, and Analyst Review

    The European oral anticoagulants market has the second-largest market share due to the rising incidence of cardiovascular disease, increasing the use of blood-thinning medications. For instance, the European Cardiovascular Disease Statistics show that more than 45% of all deaths in Europe are attributable to cardiovascular disease. Moreover, the existence of top pharma and biotech companies involved in therapeutic development and well-established healthcare infrastructure is fueling the overall regional market's growth to a large extent. Further, the German oral anticoagulants market held the largest market share, and the UK oral anticoagulants market was the fastest-growing market in the European region.

    The Asia-Pacific Oral Anticoagulants Market will likely grow at the fastest CAGR from 2024 - 2032. This region's increased awareness of cardiovascular diseases and rising disposable income drive market growth. There are many options for advanced anticoagulant drugs (also known as blood thinners) to help patients feel better due to the prevalence of cardiovascular diseases. Moreover, China’s oral anticoagulants market held the largest market share, and the Indian oral anticoagulants market was the fastest-growing market in the Asia-Pacific region.

    Key Players and Competitive Insights

    Major market players have introduced oral anticoagulants to meet the urgent needs for treating blood clots. The oral anticoagulants industry is mature, with many generics available, particularly for older product launches. New entrants face challenges as they must adhere to all drug formulations created by various associations and refrain from deviating from them. The oral anticoagulants market’s major players, such as Pfizer (US), Abbott Laboratories (US), AstraZeneca Plc (UK), and others, are investing in R&D to increase the number of pipeline medications.

    The oral anticoagulants industry has recently provided novel oral and topical drugs that offer some of the most significant advantages. Key players are also pursuing various strategic market developments initiative to expand their footprint, including new product introductions, contractual agreements, mergers and acquisitions, R&D investments, and collaborative projects with other organizations. Commercializing anticoagulant products is a priority for governments and private players. Additionally, oral anticoagulants industry manufacturers are concentrating on increasing their presence in developing nations like India, Brazil, South Africa, China, and Mexico to expand business operations and look for new markets.

    Mylan N.V. is a multinational pharmaceutical company specializing in generic and specialty drugs. In addition to operating a manufacturing facility for active pharmaceutical ingredients, the company also manages a specialty division focusing on allergy, respiratory, and psychiatric therapies. Mylan N.V. declared it would pay Aspen USD 756 million in September 2020 to expand the sterile oral anticoagulants available in Europe. This agreement will assist the business in increasing its hospital clientele and accelerating the development of their biosimilars brand in Europe.

    Also, Twist Bioscience, based in South San Francisco, is a public biotechnology company that produces synthetic DNA and DNA products for customers in various industries. In October 2021, Boehringer Ingelheim International GmbH and Twist Bioscience, a high-quality artificial DNA supplier, entered into a broad research partnership to use Twist Bioscience's proprietary antibody libraries to identify the therapeutic relationship of antibodies against various Boehringer Ingelheim targets.

    Key Companies in the Oral Anticoagulants Market market include

    Industry Developments

    February 2022 Techdow USA Inc, a vertically integrated standardized injectables company, introduced Heparin Sodium Injection, USP, to the oral anticoagulants industry in the United States.

    February 2021 According to the Stony Brook study, critically ill Covid-19 patients had a lower mortality rate when receiving anticoagulation treatment based on their blood serum D-dimer levels.

    September 2020 Mylan N.V. announced the signing of an agreement to acquire Aspen Pharmacare Holdings Limited's European thrombosis business. The company will benefit from this acquisition by becoming the second-largest provider of oral anticoagulants product to European patients.

    Future Outlook

    Oral Anticoagulants Market Future Outlook

    The Global Oral Anticoagulants Market is projected to grow at a 5.53% CAGR from 2024 to 2032, driven by increasing cardiovascular diseases, aging populations, and advancements in drug formulations.

    New opportunities lie in:

    • Develop novel oral anticoagulants targeting specific patient demographics.
    • Leverage digital health technologies for patient monitoring and adherence.
    • Expand market presence in emerging economies through strategic partnerships.

    By 2035, the market is expected to exhibit robust growth, reflecting evolving healthcare needs and innovative treatment solutions.

    Market Segmentation

    Oral Anticoagulants Product Outlook

    • Novel Oral Anticoagulant
    • Warfarin

    Oral Anticoagulants Regional Outlook

    • US
    • Canada
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
    • Middle East
    • Africa
    • Latin America

    Oral Anticoagulants Disease Indication Outlook

    • Atrial Fibrillation
    • Deep Vein Thrombosis (DVT)
    • Pulmonary Embolism (PE)
    • Heart Attacks

    Oral Anticoagulants Distribution Channel Outlook

    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024 USD 24.76 billion
    Market Size 2035 44.77 (Value (USD Billion))
    Compound Annual Growth Rate (CAGR) 5.53% (2025 - 2035)
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2018-2022
    Market Forecast Units Value (USD Billion)
    Report Coverage Market Competitive Landscape, Revenue Forecast, Growth Factors, and Trends
    Segments Covered Product, Disease Indication, Distribution Channel, and Region
    Geographies Covered Europe, North America, Asia Pacific, and the Rest of the World
    Countries Covered The U.S., Germany, Canada, U.K., Italy, France, Spain, Japan, China, Australia, India, South Korea, and Brazil
    Key Companies Profiled AstraZeneca Plc (UK), Pfizer (US), Boehringer Ingelheim GmbH (Germany), Daiichi Sankyo Company Ltd (Japan), Abbott Laboratories (US), Eli Lilly & Company (US), GlaxoSmithKline Plc (UK), Portola Pharmaceuticals Inc (US), Medicure (Canada), Johnson & Johnson Services Inc (US)
    Key Market Opportunities Increasing R&D spending in the pharmaceutical industry Emerging demands for novel therapeutics
    Key Market Dynamics Increased prevalence of heart diseases and venous thromboembolism (VTE) Introduction of novel oral anticoagulants drugs
    Market Size 2025 26.13 (Value (USD Billion))

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    How much is the oral anticoagulants market?

    The oral anticoagulants market size was valued at USD 22.76 Billion in 2023.

    What is the growth rate of the oral anticoagulants market?

    The market is anticipated to grow at a CAGR of 5.53% in the forecast period, 2024-2032.

    Which region accounted for the largest market share for oral anticoagulants?

    North America held the largest revenue share of the market.

    Who are the key players in the oral anticoagulants market?

    The key players in the market are Pfizer (US), AstraZeneca Plc (UK), Boehringer Ingelheim GmbH (Germany), Daiichi Sankyo Company Ltd (Japan), Abbott Laboratories (US), Eli Lilly & Company (US), GlaxoSmithKline Plc (UK), Portola Pharmaceuticals Inc (US), Medicure (Canada), and Johnson & Johnson Services Inc (US).

    Which product led the oral anticoagulants market?

    The novel oral anticoagulant category dominated the market in 2023.

    Which disease indication had the largest market share in the oral anticoagulants market?

    Pulmonary Embolism (PE) had the most significant market share.

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