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    United States Photodynamic Therapy Market

    ID: MRFR/Pharma/19151-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    United States Photodynamic Therapy Market Size, Growth Research Report By Product Type (Photosensitizer Drugs and Photodynamic Therapy Devices), By Light Source (Lasers, Light Emitting Diodes (LEDs), Lamps, and Others), By Application (Cancer, Actinic Keratosis (AK), Psoriasis, Acne, and Others), By End User (Hospitals, Cancer Treatment Centers, Cosmetic and Dermatology Clinics, and Others), – Competitor Industry Analysis and Trends Forecast Till 2035

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    United States Photodynamic Therapy Market Infographic
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    United States Photodynamic Therapy Market Summary

    The United States Photodynamic Therapy market is projected to experience substantial growth from 1895.17 USD Billion in 2024 to 4242.99 USD Billion by 2035.

    Key Market Trends & Highlights

    United States Photodynamic Therapy Key Trends and Highlights

    • The market is expected to grow at a compound annual growth rate of 7.6 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 4242.9 USD Billion, indicating robust expansion.
    • in 2024, the market is valued at 1895.17 USD Billion, reflecting a strong foundation for future growth.
    • Growing adoption of photodynamic therapy due to increasing awareness of its benefits is a major market driver.

    Market Size & Forecast

    2024 Market Size 1895.17 (USD Billion)
    2035 Market Size 4242.99 (USD Billion)
    CAGR (2025-2035) 7.60%

    Major Players

    Gladerma S.A., Biofrontera, Novartis AG, Lumibird (Quantel Medical), Theralase Technologies Inc., Quest Pharmatech, Inc., Hologic, Inc., Biolitec AG, Photocure ASA, IPG Photonics Corporation, Sun Pharmaceutical Industries Ltd., Valeant Pharmaceuticals International, Inc.

    United States Photodynamic Therapy Market Trends

    Increasing demand for the photosensitizer drugs is driving the market growth.

    Chemical components or medications known as photosensitizers are used with light to treat various cancer types. The cancer cells are destroyed by photosensitizers, which absorb light and transform into a different form. The regulatory bodies of the world have approved a large number of medications to treat cancer. In September 2021, for example, Soligenix, Inc. reported that the FDA's Office of Orphan Products Development had designated the active ingredient hypericin for use as an orphan drug for the treatment of T-cell lymphoma, expanding the target population beyond cutaneous T-cell lymphoma.

    Increasing R&D spending by industry participants to find novel photosensitizers that enhance clinical outcomes is projected to propel the growth of the market CAGR during the projected period. Because of technological developments that have minimized side effects and increased public awareness, photodynamic treatment devices are expected to grow profitably. Increased segmental expansion in the market is anticipated due to the rise in cancer cases and the expanding use of photodynamic therapy as a treatment. According to the National Board of Health and Welfare, the United States Cancer Registry received reports of 68,318 malignant tumors from 62,555 individuals in 2020.

    The number of cancer-related deaths was significantly lower than the number of people who were diagnosed with the disease. Over the forecast period, the segment is expected to rise due to the increasing application of photodynamic treatment for various cancers, including lung and breast cancer. 

    Additionally, because minimally invasive procedures involve less discomfort, require shorter recovery periods, and have fewer consequences, patients frequently favor them over standard surgical methods. PDT, a minimally invasive technique, supports this preference. Compared to conventional surgical procedures, minimally invasive therapies typically have a smaller financial impact on healthcare. Patients and healthcare professionals find this financial benefit attractive, encouraging PDT's growing use. Patients who receive less invasive treatments can typically return to their regular activities sooner because of their faster recovery. PDT enhances patients' quality of life by its tailored approach, which minimizes damage to healthy tissues.

    Thus driving the Photodynamic Therapy market revenue.

    The increasing adoption of photodynamic therapy in the treatment of various cancers and dermatological conditions suggests a growing recognition of its efficacy and safety among healthcare professionals.

    U.S. National Institutes of Health

    United States Photodynamic Therapy Market Drivers

    Market Growth Projections

    The Global United States Photodynamic Therapy Market Industry is projected to experience substantial growth in the coming years. With a market value of 1895.2 USD Billion in 2024, it is expected to reach 4242.9 USD Billion by 2035. This growth trajectory indicates a compound annual growth rate of 7.6% from 2025 to 2035. Such projections reflect the increasing demand for effective treatment options, driven by factors such as rising cancer prevalence, technological advancements, and expanding applications. The market's robust growth is indicative of a broader trend towards innovative therapies that prioritize patient outcomes and enhance the quality of care.

    Technological Advancements

    Technological innovations in photodynamic therapy equipment and techniques are propelling the Global United States Photodynamic Therapy Market Industry forward. Advances in laser technology, light delivery systems, and photosensitizers enhance the efficacy and safety of treatments. These innovations not only improve patient outcomes but also expand the range of treatable conditions, including skin disorders and certain types of tumors. As the market evolves, the integration of artificial intelligence and imaging technologies is likely to further refine treatment protocols. This continuous evolution suggests a promising trajectory for the market, with a compound annual growth rate of 7.6% projected from 2025 to 2035.

    Rising Prevalence of Cancer

    The increasing incidence of various cancers in the United States is a primary driver for the Global United States Photodynamic Therapy Market Industry. As cancer rates rise, the demand for effective treatment options, such as photodynamic therapy, grows. In 2024, the market is valued at approximately 1895.2 USD Billion, reflecting the urgent need for innovative therapies. Photodynamic therapy offers a minimally invasive alternative, which is appealing to both patients and healthcare providers. The projected growth of the market indicates that by 2035, the value could reach 4242.9 USD Billion, suggesting a robust expansion driven by the need for advanced cancer treatments.

    Growing Awareness and Acceptance

    Increased awareness and acceptance of photodynamic therapy among healthcare professionals and patients are driving the Global United States Photodynamic Therapy Market Industry. Educational initiatives and clinical evidence supporting the effectiveness of this therapy have contributed to its growing reputation as a viable treatment option. As more practitioners become familiar with its benefits, the adoption rate is expected to rise. This trend is particularly evident in dermatology and oncology, where photodynamic therapy is increasingly utilized. The market's expansion is indicative of a broader shift towards embracing innovative treatment modalities that prioritize patient-centered care.

    Regulatory Support and Approvals

    Regulatory bodies in the United States are increasingly supporting the development and approval of photodynamic therapy treatments, which is a significant driver for the Global United States Photodynamic Therapy Market Industry. The Food and Drug Administration has streamlined the approval process for certain photodynamic agents, facilitating quicker access to innovative therapies. This regulatory support not only encourages research and development but also instills confidence in manufacturers and investors. As new products enter the market, the competitive landscape is likely to become more dynamic, further stimulating growth in the sector.

    Expanding Applications Beyond Oncology

    The expanding applications of photodynamic therapy beyond oncology are contributing to the growth of the Global United States Photodynamic Therapy Market Industry. Initially focused on cancer treatment, photodynamic therapy is now being explored for various conditions, including acne, psoriasis, and age-related macular degeneration. This diversification of applications opens new revenue streams and attracts a broader patient demographic. As research continues to uncover additional therapeutic uses, the market is poised for significant growth. The potential for photodynamic therapy to address a wide range of health issues enhances its appeal and underscores its role in modern medical practice.

    Market Segment Insights

    Photodynamic Therapy Product Type Insights

    Based on Product Type, the United States Photodynamic Therapy market segmentation includes photosensitizer drugs and photodynamic therapy devices. The photosensitizer drugs segment mostly dominated the market. Photosensitizer medications ensure a more accurate and targeted course of treatment because they are designed to concentrate in target cells selectively. This selectivity decreases the possibility of damage to the nearby healthy tissues. The positive patient outcomes and expanding acceptance of photodynamic therapy in clinical practice have led to a rise in the use of photosensitizer drugs.

    Given the widespread use of photodynamic therapy in treating many cancers, photosensitizer drugs are a crucial component of cancer therapy. Accurately targeting and eliminating cancer cells has been a major factor in the popularity of photosensitizer-based photodynamic treatment.

    The photodynamic therapy devices category is anticipated to be the fastest growing. Photodynamic therapy is used to treat several dermatological issues, including actinic keratosis, acne, and specific kinds of skin lesions. It works very well to improve the skin's texture and treat precancerous skin disorders. Photodynamic therapy is used in ophthalmology for age-related macular degeneration (AMD) and other eye disorders. Photosensitizing chemicals are injected to target and eliminate aberrant blood vessels in the afflicted eye, and light is delivered to target and eliminate aberrant blood vessels in the afflicted eye.

    Figure 1: United States Photodynamic Therapy Market, by Product Type, 2023 & 2032 (USD Billion)

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    Photodynamic Therapy Light Source Insights

    Based on Light Source, the United States Photodynamic Therapy market segmentation includes lasers, light-emitting diodes (LEDs), lamps, and others. The lasers category earned the greatest revenue. The accurate and regulated application of light energy using lasers is necessary to initiate photosensitizing photodynamic treatment (PDT) medications. This precision lessens damage to neighboring healthy tissues while successfully treating the targeted location. Because of their adaptability, lasers can be used for various PDT operations and are employed in a wide range of medical applications. Because laser-based photodynamic therapy (PDT) is concentrated, it has fewer side effects and issues than various other treatment techniques.

    For several medical conditions, laser-based PDT is the superior choice.

    The market for photodynamic therapy light emitting diodes (LEDs) segment is anticipated to grow fastest during the forecast period. In general, LED technology is less expensive than conventional laser systems. Demand for LED-based PDT devices rises because of their cost, which enables a wider range of healthcare facilities to use them.

    Photodynamic Therapy Application Insights

    Based on Application, the United States Photodynamic Therapy market segmentation includes cancer, actinic keratosis (AK), psoriasis, acne, and others. The cancer category has the largest market share. It is anticipated to increase dramatically shortly. Cancer is a significant and pervasive health risk worldwide. The need for targeted and effective therapeutic techniques, such as photodynamic therapy, has increased due to the rising incidence of many types of cancer.

    Additionally, photodynamic therapy has shown promising results in treating several malignancies. It kills cancer cells by using compounds that are photosensitized to light. As patients and medical professionals become more informed about novel and alternative cancer treatments, the need for photodynamic therapy has increased. This is particularly relevant for certain cancer types where PDT has demonstrated potential.

    The acne category is expected to have the quickest rate. The customized technique known as photodynamic treatment targets and eliminates acne-causing bacteria and sebaceous glands by using light to activate photosensitizing compounds. In addition, patients are increasingly turning to alternatives to traditional acne treatments, including topical creams and oral medications, which may have unfavorable side effects or be ineffective. Because PDT is non-invasive, has little risk of side effects, and can be tailored to each patient's skin type, it is a popular choice for those seeking effective acne therapy.

    Photodynamic Therapy End User Insights

    Based on End Users, the United States Photodynamic Therapy market segmentation includes hospitals, cancer treatment centers, cosmetic and dermatology clinics, and others. The hospitals category has the largest market share. Hospitals provide a controlled and established clinical setting necessary for photodynamic therapy administration. PDT treatments are guaranteed safe and effective because hospital infrastructure and facilities are designed to handle medical procedures. For photodynamic therapy, specialized equipment, including light sources and diagnostic instruments, is required. The availability of PDT equipment is constant because hospitals usually have access to state-of-the-art medical technology.

    The cosmetic and dermatology clinics category is expected to have the quickest rate. There is an increasing need for cosmetic procedures to address skin conditions and enhance attractiveness. Dermatology and cosmetic clinics offer PDT as an effective, non-invasive treatment option for various skin problems, attracting a larger patient base seeking cosmetic solutions. The benefits of PDT for skin rejuvenation and therapy are now better understood, which has led to increased patient education.

    Dermatology and cosmetic surgery clinics are essential for the diffusion of knowledge, which helps to explain why PDT treatments are growing in popularity and driving the segment's rise in the photodynamic therapy market.

    Photodynamic Therapy Country Insights

    The presence of major companies in the United States market, the rise in demand for new biologics to treat cancer, the rapid adoption of photodynamic therapy, and the introduction of new products by industry participants. The actinic keratosis market in the United States is experiencing growth due to several factors, including an increase in the number of cosmetologists offering photodynamic therapy, a rise in product approvals by the US Food and Drug Administration, and a surge in the use of photodynamic therapy for this purpose.

    In December 2021, Biofrontera Inc. announced that the first participant in a Phase 1 study assessing the safety and tolerability of photodynamic therapy (PDT) for actinic keratosis (AK) had been enrolled. PDT involves utilizing three tubes of Ameluz in conjunction with the company's BF-RhodoLED XL lamp. It is anticipated that these product approvals will propel the US market.

    Get more detailed insights about United States Photodynamic Therapy Market Research Report - Forecast Till 2034

    Key Players and Competitive Insights

    Major industry players are expected to invest extensively in R&D to extend their product lines, which would drive additional growth in the market for photodynamic therapy systems. Players in the industry launch a variety of tactical measures to increase their market penetration in parallel with these significant developments in the market. These actions consist of contracts, mergers and acquisitions, increased investments, cooperation with other businesses, and new product types of light sources. To grow and thrive in a more competitive and dynamic market, it must provide reasonably priced products. This is because of the photodynamic therapy industry.

    Major United States Photodynamic Therapy market players are attempting to increase market demand by investing in research and development operations, including Gladerma S.A., Biofrontera, Novartis AG, Lumibird (Quantel Medical), Theralase Technologies Inc., Quest Pharmatech, Inc., Hologic, Inc., Biolitec AG, Photocure ASA, IPG Photonics Corporation, Sun Pharmaceutical Industries Ltd., and Valeant Pharmaceuticals International, Inc.

    Key Companies in the United States Photodynamic Therapy Market market include

    Industry Developments

    January 2023:The international biopharmaceutical company Biofrontera AG announced that the U.S. Patent Office (USPTO) had sent a notice of allowance for the application "Photodynamic therapy comprising two light exposures at different wavelengths" (US Appl. No. 17/269,816) to its wholly owned subsidiary Biofrontera Bioscience GmbH. This patent covers several inventions related to a novel lighting technique for Photodynamic Therapy (PDT) treatment of dermatological skin disorders.

    March 2022:The US patent No. 11,235,169 for the BF-RhodoLED XL illumination device was previously issued to Biofrontera Inc. The company has announced that the device is now listed in the FDA publication "Approved Drug Products with Therapeutic Equivalency Evaluations, or the Orange Book.

    Future Outlook

    United States Photodynamic Therapy Market Future Outlook

    The United States Photodynamic Therapy Market is projected to grow at a 7.60% CAGR from 2025 to 2035, driven by technological advancements, increasing cancer prevalence, and rising awareness of minimally invasive treatments.

    New opportunities lie in:

    • Develop novel photosensitizers to enhance treatment efficacy and patient outcomes.
    • Expand telemedicine platforms for remote photodynamic therapy consultations and follow-ups.
    • Invest in partnerships with healthcare providers to integrate photodynamic therapy into standard oncology practices.

    By 2035, the market is expected to demonstrate robust growth, establishing itself as a cornerstone in cancer treatment.

    Market Segmentation

    Outlook

    • Hospitals
    • Cancer Treatment Centers
    • Cosmetic and Dermatology Clinics
    • Others

    Photodynamic Therapy End User Outlook

    • Hospitals
    • Cancer Treatment Centers
    • Cosmetic and Dermatology Clinics
    • Others

    Photodynamic Therapy Product Type Outlook

    • Photosensitizer Drugs
    • Photodynamic Therapy Devices

    Photodynamic Therapy Application Outlook

    • Cancer
    • Actinic Keratosis (AK)
    • Psoriasis
    • Acne
    • Others

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024 1,895.17 (USD Billion)
    Market Size 2025 2,039.24 (USD Billion)
    Market Size 2035 4242.99 (USD Billion)
    Compound Annual Growth Rate (CAGR) 7.60% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2020 - 2024
    Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments Covered Product Type, Light Source, Application, and End User
    Countries Covered United States
    Key Companies Profiled Gladerma S.A., Biofrontera, Novartis AG, Lumibird (Quantel Medical), Theralase Technologies Inc., Quest Pharmatech, Inc., Hologic, Inc., Biolitec AG, Photocure ASA, IPG Photonics Corporation, Sun Pharmaceutical Industries Ltd., and Valeant Pharmaceuticals International, Inc.
    Key Market Opportunities Partnerships with pharmaceutical companiesInnovations in imaging technologies.
    Key Market Dynamics Rising incidence of skin disorders and cancer Growing government investment in research and development

    FAQs

    How much is the United States Photodynamic Therapy market?

    The United States Photodynamic Therapy market size was valued at USD 1636.8 Billion in 2023.

    What is the growth rate of the United States Photodynamic Therapy market?

    The market is projected to grow at a CAGR of 7.60% during the forecast period, 2025-2034.

    Who are the key players in the United States Photodynamic Therapy market?

    The key players in the market are Gladerma S.A., Biofrontera, Novartis AG, Lumibird (Quantel Medical), Theralase Technologies Inc., Quest Pharmatech, Inc., Hologic, Inc., Biolitec AG, Photocure ASA, IPG Photonics Corporation, Sun Pharmaceutical Industries Ltd., and Valeant Pharmaceuticals International, Inc.

    Which Product Type led the United States Photodynamic Therapy market?

    The Photosensitizer Drugs category dominated the market in 2023.

    Which Light Source had the largest market share in the United States Photodynamic Therapy market?

    The Lasers category had the largest share of the market.

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