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    Antibody Drug Discovery Market

    ID: MRFR/HC/10534-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    Antibody Drug Discovery Market Size, Growth Research Report By Type (Monoclonal Antibodies, Polyclonal Antibodies, Antibody-Drug Conjugates, Bispecific Antibodies), By Technology (Recombinant DNA Technology, Hybridoma Technology, Phage Display Technology, Transgenic Technology), By Application (Therapeutic Applications, Diagnostic Applications, Research Applications), By End Use (Pharmaceutical Companies, Biotechnology Companies, Research Institutions) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Afric...

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    Antibody Drug Discovery Market Summary

    As per Market Research Future Analysis, the Antibody Drug Discovery Market was valued at 6.76 USD Billion in 2024 and is projected to grow to 17.28 USD Billion by 2035, driven by the increasing prevalence of chronic diseases and demand for targeted therapies. The market is characterized by advancements in biotechnology and significant investments in research and development.

    Key Market Trends & Highlights

    Key trends driving the Antibody Drug Discovery Market include technological advancements and increasing collaboration among stakeholders.

    • The market is expected to grow from 48.97 USD Billion in 2024 to 89.6 USD Billion by 2035, with a CAGR of 5.65% from 2025 to 2035.
    • Monoclonal Antibodies are projected to dominate the market, reaching 36.8 USD Billion by 2035.
    • The global biotechnology market is anticipated to reach approximately 775 USD Billion by 2024, emphasizing the relevance of innovative technologies.
    • North America is expected to hold the largest market share, valued at 22.5 USD Billion in 2024.

    Market Size & Forecast

    2024 Market Size USD 6.76 Billion
    2035 Market Size USD 17.28 Billion
    CAGR (2025-2035) 8.90%

    Major Players

    Key players include Genentech, Merck and Co, Takeda, Pfizer, Roche, AbbVie, Eli Lilly, Bristol Myers Squibb, Johnson and Johnson, GSK, Novartis, Regeneron Pharmaceuticals, AstraZeneca, Amgen, and Sanofi.

    Antibody Drug Discovery Market Trends

    Advancements in biotechnology and an increase in investment in research and development are driving significant trends in the Antibody Drug Discovery Market.

    The increasing prevalence of chronic diseases, such as cancer and autoimmune disorders, is a significant market driver, as it is increasing the demand for effective therapeutic options.

    Furthermore, the advancement of personalized medicine is encouraging the creation of antibody therapies that are specifically designed to target specific patient demographics, thereby improving the efficacy of treatment.

    Innovative antibody drugs are also considerably accelerated in the market in various regions, particularly in Europe and North America, due to regulatory support and streamlined approval processes. 

    The development of antibody-drug conjugates (ADCs) and bispecific antibodies, which are establishing new pathways for targeted therapy, are among the opportunities to be investigated in this market.

    Additionally, there is an increasing interest in utilizing artificial intelligence and machine learning to improve the efficiency of antibody discovery processes.

    Ultimately, this technological integration can lead to a quicker turnaround for drug development, which will improve patient care and reduce healthcare costs.

    Additionally, the emphasis on emerging markets creates growth prospects, as these regions are investing in innovative treatment solutions and expanding their healthcare infrastructures.

    The antibody drug discovery landscape is expected to undergo substantial change in the years ahead, as a result of the expanding global population and the advancement of scientific knowledge.

     

    The ongoing advancements in antibody drug discovery are poised to enhance therapeutic options, potentially transforming treatment paradigms across various diseases.

    U.S. National Institutes of Health (NIH)

    Antibody Drug Discovery Market Drivers

    Market Growth Projections

    The Global Antibody Drug Discovery Market Industry is projected to experience substantial growth over the next decade. With an anticipated market size of 49.0 USD Billion in 2024, it is expected to reach 89.6 USD Billion by 2035. This growth reflects a compound annual growth rate of 5.65% from 2025 to 2035. Such projections indicate a robust demand for antibody-based therapies, driven by various factors including technological advancements, increased investment in research and development, and the rising prevalence of chronic diseases. The market's trajectory suggests a promising future for stakeholders involved in antibody drug discovery.

    Increased Investment in R&D

    The Global Antibody Drug Discovery Market Industry benefits from heightened investment in research and development by both public and private sectors. Governments and pharmaceutical companies are allocating significant resources to discover and develop novel antibody therapies. For instance, the National Institutes of Health in the United States has increased funding for antibody research, recognizing its potential to address unmet medical needs. This influx of capital fosters innovation and accelerates the development of new therapies, thereby expanding the market. As the industry continues to attract investment, the potential for breakthroughs in antibody drug discovery remains promising.

    Advancements in Biotechnology

    Technological advancements in biotechnology significantly enhance the Global Antibody Drug Discovery Market Industry. Innovations in genetic engineering, such as CRISPR and monoclonal antibody development, enable the creation of highly specific and effective therapeutic agents. These advancements facilitate the rapid identification and validation of new antibody candidates, streamlining the drug discovery process. For example, the development of bispecific antibodies has opened new avenues for treating complex diseases. Consequently, the market is poised for substantial growth, driven by the continuous evolution of biotechnological tools and methodologies that improve the efficiency and efficacy of antibody drug discovery.

    Rising Prevalence of Chronic Diseases

    The increasing incidence of chronic diseases globally drives the Global Antibody Drug Discovery Market Industry. Conditions such as cancer, autoimmune disorders, and infectious diseases necessitate innovative therapeutic solutions. For instance, the World Health Organization indicates that cancer cases are projected to rise by 70 percent over the next two decades. This surge in chronic diseases creates a substantial demand for antibody-based therapies, which are often more targeted and effective than traditional treatments. As a result, the market is expected to grow from 49.0 USD Billion in 2024 to 89.6 USD Billion by 2035, reflecting a compound annual growth rate of 5.65% from 2025 to 2035.

    Growing Demand for Personalized Medicine

    The shift towards personalized medicine is a pivotal driver of the Global Antibody Drug Discovery Market Industry. Patients increasingly seek treatments tailored to their unique genetic profiles, which enhances therapeutic efficacy and minimizes adverse effects. Antibody therapies, with their ability to target specific biomarkers, align well with this trend. As healthcare systems worldwide embrace personalized approaches, the demand for antibody-based treatments is expected to rise. This trend is likely to contribute to the market's growth trajectory, as personalized medicine becomes an integral component of modern healthcare strategies.

    Regulatory Support and Streamlined Approval Processes

    Regulatory bodies globally are increasingly supportive of antibody drug development, which positively influences the Global Antibody Drug Discovery Market Industry. Initiatives aimed at expediting the approval process for innovative therapies, such as the FDA's Breakthrough Therapy designation, facilitate faster access to the market. This regulatory environment encourages pharmaceutical companies to invest in antibody drug discovery, knowing that their products may reach patients more swiftly. As a result, the market is likely to experience accelerated growth, driven by the favorable regulatory landscape that promotes innovation and expedites the delivery of new therapies.

    Market Segment Insights

    Antibody Drug Discovery Market Type Insights

    The Antibody Drug Discovery Market is a growing segment within the pharmaceuticals and biotechnology industries, reached a valuation of 48.97 USD Billion in 2024 and further expanding to 89.6 USD Billion by 2035.

    This market is intricately segmented into Monoclonal Antibodies, Polyclonal Antibodies, Antibody-Drug Conjugates, and Bispecific Antibodies, each holding its significance in the therapeutic landscape.

    Monoclonal Antibodies dominated the market with a valuation of 20.0 USD Billion in 2024, growing to 36.0 USD Billion in 2035, owing to their specialized targeting of specific antigens, resulting in effective treatments for diseases like cancer and autoimmune disorders.Polyclonal Antibodies, valued at 10.0 USD Billion in 2024 and expected to rise to 18.0 USD Billion by 2035, play a crucial role in diagnostic applications and therapeutic use due to their ability to recognize multiple epitopes on antigens, providing a broader immune response.

    Antibody Drug Discovery Market Technology Insights

    The Technology segment of the Antibody Drug Discovery Market plays a crucial role in advancing therapeutic options and enhancing drug efficacy. The overall market was valued at 48.97 USD Billion in 2024, reflecting the growing demand for innovative antibody-based therapies.

    Within this segment, Recombinant DNA Technology has gained significant traction due to its capability to produce highly specific antibodies, streamlining the research and development process.

    Hybridoma Technology remains a foundational method for producing monoclonal antibodies, establishing a strong foothold in various therapeutic applications.Phage Display Technology offers an efficient way to discover new antibodies by allowing scientists to screen vast libraries of antibodies, offering a significant advantage in the antibody discovery landscape.

    Meanwhile, Transgenic Technology facilitates the creation of animal models that express human antibodies, providing essential insights into human biology and disease mechanisms.

    The market is driven by the increasing prevalence of chronic diseases, rising investments in blue biotechnology, and enhanced government support for research initiatives.However, challenges such as high development costs and regulatory hurdles might impact market dynamics. Overall, the Antibody Drug Discovery Market underscores the importance of these technologies in shaping the future of healthcare.

    Antibody Drug Discovery Market Application Insights

    The Antibody Drug Discovery Market is witnessing significant growth, with the overall market valued at 48.97 billion USD in 2024 and projected to rise to 89.6 billion USD by 2035.

    The Application segment plays a crucial role in this market, comprising Therapeutic Applications, Diagnostic Applications, and Research Applications.

    Therapeutic Applications dominate the landscape, as they offer innovative treatments for chronic diseases like cancer and autoimmune disorders, which have seen an increasing prevalence globally.

    Antibody Drug Discovery Market End Use Insights

    The Antibody Drug Discovery Market is experiencing substantial growth, with a projected market value of USD 48.97 billion in 2024, driven largely by its diverse end-use applications.

    Pharmaceutical companies play a crucial role in this segment, focusing on innovative drug development processes that harness the potential of monoclonal antibodies.

    The biotechnology companies are equally significant, as they specialize in harnessing biological systems to create highly targeted therapeutic agents that address complex diseases.

    Research institutions contribute extensively to this market, providing essential insights and advancements through studies and trials that pave the way for new drug discoveries.The market’s growth is propelled by rising demand for effective treatments for chronic conditions, advancements in technology, and increased collaboration among stakeholders. However, challenges such as stringent regulatory approvals and high development costs persist.

    Opportunities for expansion remain prominent in personalized medicine and biologics, positioning the Antibody Drug Discovery Market for continued success as it leverages the strengths of pharmaceutical entities, biotechnological innovations, and research advancements.

    Get more detailed insights about Antibody Drug Discovery Market Research Report—Global Forecast till 2035

    Regional Insights

    The Antibody Drug Discovery Market is poised for substantial growth, particularly across its regional segments, highlighting the varying demands and investments in biopharmaceutical research.

    In North America, the market was valued at 22.0 USD Billion in 2024 and is expected to grow to 40.0 USD Billion by 2035, representing a majority holding that underscores the region's strong biotechnology infrastructure and funding capabilities.

    Europe follows closely, with a market value of 15.0 USD Billion in 2024, projected to rise to 28.0 USD Billion in 2035, benefitting from comprehensive regulatory frameworks and collaborative research initiatives.

    In South America, the market stood at 3.5 USD Billion in 2024 and is expected to reach 6.0 USD Billion in 2035, reflecting a developing interest in expanding biomanufacturing and research centers.

    The Asia Pacific region is notable as well, with a valuation of 7.5 USD Billion in 2024, anticipated to grow to 12.0 USD Billion by 2035, driven by increasing investments in healthcare and rapid advancements in genetic research.

    Meanwhile, the Middle East and Africa, though smaller, with a value of 1.97 USD Billion in 2024, projected at 3.6 USD Billion in 2035, show potential growth due to emerging markets and local pharmaceutical initiatives.

    Together, these regions contribute to the evolving landscape of the Antibody Drug Discovery Market, driven by innovations in therapeutic development and a strong demand for targeted therapies, with each segment playing an essential role in the overall market paradigm.

    Antibody Drug Discovery Market Regional Insights

    Key Players and Competitive Insights

    The Antibody Drug Discovery Market is characterized by intense competition as a multitude of players engage in the development and research of novel therapeutics.

    As the demand for targeted therapies and biologics grows, various companies branch into this specific sector, tapping into a breadth of technological advancements in antibody engineering, screening, and production processes.

    Collaborative partnerships, strategic mergers and acquisitions, and innovations are prevalent as organizations aim to enhance their portfolios and leverage new scientific findings.

    The market landscape is dynamic, featuring established pharmaceutical giants and emerging biopharmaceutical firms working together to advance antibody drug discovery.

    As the market evolves, factors such as regulatory landscapes, intellectual property rights, and shifting healthcare paradigms continually shape competitive strategies among these companies.

    In the context of the Antibody Drug Discovery Market, Novartis stands as a formidable player with a strong portfolio of products aimed at addressing critical therapeutic areas including oncology, multiple sclerosis, and autoimmune diseases.

    The company's commitment to innovation is evident in its robust pipeline, which focuses on monoclonal antibodies, biosimilars, and engineered antibodies. Novartis’s research and development facilities are strategically located to foster collaborations with academic institutions and biotech firms, enhancing its competitive edge.

    This company effectively leverages its extensive market presence and commendable financial resources to expedite the development of cutting-edge antibody therapies while also engaging in partnerships that open new avenues for discovery.

    Novartis’s experience and resilience in navigating regulatory challenges further contribute to its strength in the Antibody Drug Discovery Market, positioning it favorably against competitors.

    Regeneron Pharmaceuticals holds a significant position in the Antibody Drug Discovery Market, primarily due to its strong emphasis on genetic research and innovative biological therapies.

    The company is well-known for its pioneering work in monoclonal antibody development, yielding groundbreaking products that target various diseases, including cancer and eye disorders.

    Regeneron's strength lies in its proprietary VelociSuite technology platform, which streamlines the discovery and development of fully human monoclonal antibodies.

    The company demonstrates a commitment to expanding its market presence through strategic mergers and acquisitions, enhancing its capabilities and product offerings.

    Key partnerships with research institutions bolster its innovation efforts, which significantly contribute to its competitive position in the global arena.

    Moreover, Regeneron’s robust pipeline, characterized by multiple late-stage candidates, positions it favorably in responding to the dynamic needs of the global healthcare market, allowing it to maintain a leadership role in antibody drug discovery.

    Key Companies in the Antibody Drug Discovery Market market include

    Industry Developments

    In October 2024, Gilead Sciences expanded its partnership with AbTherx to improve antibody discovery technologies and develop additional therapeutic antibody programs by utilizing Atlas™ transgenic mouse platforms.Gilead's oncology immunotherapy pipeline was fortified in December 2023 by the acquisition of an exclusive license agreement with Compugen for a preclinical antibody program that targets IL-18 binding protein (COM503).Bristol Myers Squibb and Zenas BioPharma entered into a strategic alliance in September 2023, under which Bristol Myers Squibb provided an initial investment of US$50 million to facilitate the development and commercialization of obexelimab, a bispecific antibody used to treat autoimmune diseases.Mirati Therapeutics' oncology discovery platform and KRAS-targeting monoclonal antibody programs were integrated into Bristol Myers Squibb's pipeline with the completion of the US$4.8 billion acquisition of Mirati Therapeutics in October 2023.In February 2024, Bristol Myers Squibb completed the acquisition of RayzeBio for approximately US$4.1 billion.

    This acquisition provided Bristol Myers Squibb with access to radiopharmaceutical antibody platforms, including the RYZ101 pipeline, thereby expanding its modality expertise.

    Future Outlook

    Antibody Drug Discovery Market Future Outlook

    The Antibody Drug Discovery Market is poised for growth at a 8.90% CAGR from 2025 to 2035, driven by advancements in biotechnology, increasing R&D investments, and rising demand for targeted therapies.

    New opportunities lie in:

    • Invest in AI-driven platforms for enhanced antibody design and optimization. Develop partnerships with biotech firms to accelerate clinical trials and market entry. Focus on personalized medicine approaches to cater to specific patient populations.

    By 2035, the market is expected to achieve substantial growth, reflecting evolving therapeutic landscapes and increased innovation.

    Market Segmentation

    Antibody Drug Discovery Market Type Outlook

    • Monoclonal Antibodies
    • Polyclonal Antibodies
    • Antibody-Drug Conjugates
    • Bispecific Antibodies

    Antibody Drug Discovery Market End Use Outlook

    • Pharmaceutical Companies
    • Biotechnology Companies
    • Research Institutions

    Antibody Drug Discovery Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Antibody Drug Discovery Market Technology Outlook

    • Recombinant DNA Technology
    • Hybridoma Technology
    • Phage Display Technology
    • Transgenic Technology

    Antibody Drug Discovery Market Application Outlook

    • Therapeutic Applications
    • Diagnostic Applications
    • Research Applications

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024 48.97 (USD Billion)
    Market Size 2035 17.28 (USD Billion)
    Compound Annual Growth Rate (CAGR) 8.90% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Novartis, Regeneron Pharmaceuticals, Merck, Pfizer, Gilead Sciences, GlaxoSmithKline, Biogen, Amgen, AstraZeneca, Eli Lilly, Sanofi, Johnson & Johnson, Roche, BristolMyers Squibb, AbbVie
    Segments Covered Type, Technology, Application, End Use, Regional
    Key Market Opportunities Increasing demand for personalized medicine, Advancements in antibody engineering technologies, Expanding applications in autoimmune diseases, Rising investment in biopharmaceutical research, Growth in collaborations and partnerships
    Key Market Dynamics Increasing cancer prevalence, Advancements in technology, Rising investment in R&D, Growing adoption of personalized medicine, Expanding biologics market
    Countries Covered North America, Europe, APAC, South America, MEA
    Market Size 2025 7.36 (USD Billion)

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What was the expected market size of the Antibody Drug Discovery Market in 2024?

    The Antibody Drug Discovery Market was valued at 48.97 USD Billion in 2024.

    What is the projected market size for the Antibody Drug Discovery Market by 2035?

    By 2035, the Antibody Drug Discovery Market is anticipated to reach a value of 89.6 USD Billion.

    What is the expected CAGR for the Antibody Drug Discovery Market from 2025 to 2035?

    The expected CAGR for the Antibody Drug Discovery Market from 2025 to 2035 is 5.65%.

    Which region held the largest market share in the Antibody Drug Discovery Market in 2024?

    North America held the largest market share in 2024 with a value of 22.0 USD Billion.

    What will be the market size for Monoclonal Antibodies in 2035?

    The market size for Monoclonal Antibodies is projected to be 36.0 USD Billion by 2035.

    Which companies are key players in the Antibody Drug Discovery Market?

    Key players in the market include Novartis, Regeneron Pharmaceuticals, Merck, and Pfizer, among others.

    What is the expected growth rate for the Asia Pacific region in the Antibody Drug Discovery Market from 2025 to 2035?

    The Asia Pacific region is expected to see significant growth, reaching 12.0 USD Billion by 2035.

    What market value was expected for Antibody-Drug Conjugates in 2024?

    Antibody-Drug Conjugates was valued at 12.0 USD Billion in 2024.

    What challenges are currently impacting the Antibody Drug Discovery Market?

    Challenges include stringent regulations and high costs of antibody drug development.

    Which segment is expected to show the most growth in the Antibody Drug Discovery Market by 2035?

    Monoclonal Antibodies are expected to show the most growth, valued at 36.0 USD Billion in 2035.

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