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    US Influenza Vaccination Market

    ID: MRFR/Pharma/13136-HCR
    100 Pages
    Rahul Gotadki
    September 2025

    US Influenza Vaccination Market Research Report By Influenza Type (Seasonal, Zoonotic), By Manufacturing Technology (Egg-based, Cell culture-based, Recombinant-based), By Vaccine Type (Quadrivalent Influenza Vaccines, Trivalent Influenza Vaccines) and By End User (Hospitals & Clinics, Research Organizations & Academic Institutes, others) - Forecast to 2035

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    US Influenza Vaccination Market Infographic
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    US Influenza Vaccination Market Summary

    The US Influenza Vaccination market is projected to grow from 2.1 USD Billion in 2024 to 4.5 USD Billion by 2035.

    Key Market Trends & Highlights

    US Influenza Vaccination Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 7.17 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 4.5 USD Billion, indicating robust growth.
    • In 2024, the market is valued at 2.1 USD Billion, laying a strong foundation for future expansion.
    • Growing adoption of vaccination programs due to increasing awareness of public health is a major market driver.

    Market Size & Forecast

    2024 Market Size 2.1 (USD Billion)
    2035 Market Size 4.5 (USD Billion)
    CAGR (2025-2035) 7.17%

    Major Players

    Seqirus, Novartis, Merck, GlaxoSmithKline, Baxter, AstraZeneca, Inovio Pharmaceuticals, Moderna, Pfizer, Protein Sciences, AbbVie, VBI Vaccines, Sanofi, Johnson and Johnson, MedImmune

    US Influenza Vaccination Market Trends

    The US Influenza Vaccination Market is experiencing significant trends influenced by a growing awareness of public health and the increasing incidence of influenza-related complications. There is a strong drive by health authorities and organizations to promote vaccination, especially among high-risk populations such as children, the elderly, and those with chronic health conditions. The Centers for Disease Control and Prevention (CDC) consistently emphasizes the importance of annual influenza vaccines, underscoring a cultural shift towards prioritizing preventive healthcare measures.

    This focus on vaccination is a key market driver, as many states are implementing policies to improve access and affordability, ensuring that more individuals can receive their flu shots.

    In recent times, innovative vaccine technologies, including adjuvanted and recombinant vaccines, are being introduced in the US market. These advancements aim to enhance immunogenicity and protection, thus catering to a more diverse population and reinforcing public trust in vaccination. Opportunities exist in increasing the reach of these vaccines through partnerships with pharmacies and community health organizations, making it easier for individuals to get vaccinated. Additionally, educational campaigns are being deployed to address vaccine hesitancy, particularly in the wake of the COVID-19 pandemic, which has heightened awareness of infectious diseases.

    The upcoming flu seasons are anticipated to further shape the market with considerations for combination vaccines, which could protect against multiple strains or different viruses, making immunization more efficient. The incorporation of digital technologies, such as appointment scheduling apps and reminder systems for vaccinations, also presents an opportunity to enhance vaccine uptake across the nation. Overall, the US market for influenza vaccinations is set for growth driven by a combination of regulatory support, technological advancements, and increased public awareness about the value of vaccination.

    Market Segment Insights

    Influenza Vaccination Market Influenza Type Insights

    The US Influenza Vaccination Market has shown a robust framework centered around the Influenza Type segment, primarily divided into Seasonal and Zoonotic categories. Seasonal influenza vaccines are a crucial element within public health efforts and are typically updated annually to match circulating virus strains, ensuring protection for vulnerable populations during peak flu seasons. With a significant part of the US population availing seasonal vaccinations, this segment commands a noteworthy portion of the market, owing to rising awareness of influenza's impact and the push towards annual immunization.

    Various government health campaigns have underscored the importance of these vaccines, especially with increasing hospitalizations and healthcare costs related to flu outbreaks. In contrast, the Zoonotic influenza vaccines address infections that may spill over from animals to humans, representing a growing concern as the frequency of zoonotic viruses rises due to environmental changes. This category is becoming increasingly important as new strains emerge and pose significant health risks that require targeted vaccination strategies. The continuous evolution of the influenza virus necessitates an agile response from the healthcare community.

    Evolving consumer perceptions and advancements in vaccine technology are driving trends, fostering innovation aimed at enhancing vaccine efficacy and accessibility. As a result, these segments contribute significantly to the US Influenza Vaccination Market, highlighting the dynamic interplay of healthcare drivers, government support, and population health initiatives aimed at reducing influenza morbidity and mortality.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Influenza Vaccination Market Manufacturing Technology Insights

    The Manufacturing Technology segment of the US Influenza Vaccination Market encompasses various methodologies crucial for vaccine production. Among the most prominent are Egg-based, Cell culture-based, and Recombinant-based technologies. Egg-based production, historically the most widely used method, relies on inoculating fertilized chicken eggs, allowing for the growth of the virus, which is then harvested for vaccine formulation. However, Cell culture-based methods have gained traction due to their ability to produce vaccines more rapidly and without reliance on eggs, providing flexibility especially important during pandemic responses.

    Recombinant-based technology represents a significant advancement, utilizing genetic engineering to create vaccines that are more effective and can be produced in a controlled environment. The shift towards these advanced manufacturing methods is driven by the need for more efficient vaccine production in the face of evolving influenza strains and public health demands. As these methodologies evolve, they contribute directly to the overall growth and effectiveness of the US Influenza Vaccination Market, ensuring that the population is adequately protected against seasonal and pandemic influenza threats.

    Influenza Vaccination Market Vaccine Type Insights

    The US Influenza Vaccination Market offers a diverse range of vaccines categorized under Vaccine Type, which significantly impacts public health. Among these, Quadrivalent Influenza Vaccines and Trivalent Influenza Vaccines serve as primary options for vaccination. Quadrivalent vaccines are designed to protect against four different viral strains, including two influenza A and two influenza B strains, thereby providing broader coverage compared to their Trivalent counterparts, which target three strains. This broad protection is particularly crucial as it addresses the evolving nature of influenza viruses, which can vary seasonally.

    The increasing prevalence of various viral strains necessitates the use of Quadrivalent vaccines, which can effectively immunize a larger segment of the population. The demand for Trivalent Influenza Vaccines remains steady, appealing to those who prefer a traditional approach, although they have seen competition from the expanding Quadrivalent segment. The US public health initiatives and campaigns to promote influenza vaccination amplify the importance of these vaccines, driving higher vaccination rates and ultimately reducing healthcare costs associated with influenza-related illnesses.

    The trend towards more comprehensive vaccination solutions, along with heightened awareness of the need for annual flu shots, showcases the significance of both Quadrivalent and Trivalent vaccines in the ongoing efforts to control influenza outbreaks across the country.

    Influenza Vaccination Market End User Insights

    The US Influenza Vaccination Market is significantly influenced by the End User segment, which includes Hospitals and Clinics, Research Organizations and Academic Institutes, and others. Hospitals and Clinics serve as primary access points for influenza vaccinations, contributing considerably to public health by ensuring high immunization rates among vulnerable populations. Additionally, Research Organizations and Academic Institutes are integral for advancing vaccine development and studies on vaccine effectiveness, playing a vital role in enhancing the overall response to influenza outbreaks.

    This segment's importance is amplified by the increasing awareness of preventative healthcare measures in the US, driven by government initiatives that encourage vaccination. The ongoing demand for innovative vaccine solutions highlights the substantial opportunities within this market, as each segment addresses critical aspects of public health and safety. The segmentation presents a comprehensive understanding of how different entities contribute to the US Influenza Vaccination Market, addressing not only vaccination distribution but also research and development efforts essential for combating influenza effectively.

    The market continues to evolve in response to changing epidemiological data and advances in healthcare technologies, positioning it for growth in the coming years.

    Get more detailed insights about US Influenza Vaccination Market Research Report - Forecast to 2035

    Key Players and Competitive Insights

    The US Influenza Vaccination Market is characterized by a competitive landscape comprised of several key players that strive to enhance their market presence and offer innovative solutions. As the demand for effective influenza vaccines continues to grow, driven by increased awareness of vaccine efficacy and public health initiatives, companies are focusing on research and development efforts to introduce novel formulations and delivery methods. The competitive dynamics also involve factors such as pricing strategies, distribution channels, regulatory approvals, and marketing initiatives aimed at improving vaccination rates among diverse populations.

    Companies are not only competing on product efficacy but also on their ability to educate the public and engage healthcare providers, leading to a multifaceted approach to capturing market share in an increasingly health-conscious environment.

    Seqirus, a significant player in the US Influenza Vaccination Market, boasts a strong portfolio of vaccines that cater to a variety of demographic groups, including high-risk populations. Well-known for its advanced manufacturing capabilities and commitment to innovation, Seqirus focuses on producing high-quality influenza vaccines that have garnered trust among healthcare providers and patients alike. The company emphasizes strategic partnerships and collaborations within the healthcare ecosystem that allow for efficient distribution and accessibility of its vaccines.

    Moreover, Seqirus actively invests in research to improve vaccine formulations and enhance immunogenicity, further solidifying its reputation as a leader in the market. The established relationships with healthcare infrastructures provide Seqirus with a competitive edge, allowing for rapid responses to seasonal flu challenges and public health needs.

    Novartis maintains a noteworthy presence in the US Influenza Vaccination Market, primarily recognized for its comprehensive range of vaccine products and services. The company's commitment to innovation is reflected in its extensive research capabilities, leading to the development of effective influenza vaccines that meet the evolving demands of public health. Novartis has also engaged in strategic mergers and acquisitions to bolster its position in the market and expand its portfolio.

    Through such initiatives, the company has enhanced its capabilities to produce both seasonal and pandemic vaccines, ensuring availability and responsiveness during health crises. Its dedication to research, along with its established distribution network, allows Novartis to effectively reach healthcare providers, ensuring that its vaccines are widely available to the populations in need. This steadfast focus on both innovation and access underscores Novartis's strengths in the competitive landscape of the US Influenza Vaccination Market.

    Key Companies in the US Influenza Vaccination Market market include

    Industry Developments

    The US Influenza Vaccination Market has seen significant developments recently, particularly in the realm of vaccination strategies amid rising influenza cases. In September 2023, Seqirus announced its enhanced vaccination programs aiming for broader population reach, especially targeting high-risk groups. In October 2023, Pfizer and Moderna have rolled out their latest vaccine formulations to combat emerging strains of influenza, a critical component in maintaining public health. The market has experienced growth in valuation as these companies continue to innovate and expand their product offerings.

    AstraZeneca and GlaxoSmithKline are also focusing on partnerships to enhance delivery systems and ensure accessibility of vaccines. Notably, in November 2022, Merck completed its acquisition of a biotech firm to strengthen its portfolio in respiratory vaccines, reflecting a trend in market consolidation. The US government has prioritized flu vaccinations through public health campaigns, contributing to the increased demand for vaccines. These initiatives have resulted in heightened awareness and participation in vaccination programs throughout the nation, ensuring a well-coordinated effort in addressing seasonal influenza outbreaks.

    Market Segmentation

    Influenza Vaccination Market End User Outlook

    • Hospitals & Clinics
    • Research Organizations & Academic Institutes
    • others

    Influenza Vaccination Market Vaccine Type Outlook

    • Quadrivalent Influenza Vaccines
    • Trivalent Influenza Vaccines

    Influenza Vaccination Market Influenza Type Outlook

    • Seasonal
    • Zoonotic

    Influenza Vaccination Market Manufacturing Technology Outlook

    • Egg-based
    • Cell culture-based
    • Recombinant-based

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2018 1.67(USD Billion)
    MARKET SIZE 2024 2.1(USD Billion)
    MARKET SIZE 2035 4.5(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 7.174% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED Seqirus, Novartis, Merck, GlaxoSmithKline, Baxter, AstraZeneca, Inovio Pharmaceuticals, Moderna, Pfizer, Protein Sciences, AbbVie, VBI Vaccines, Sanofi, Johnson and Johnson, MedImmune
    SEGMENTS COVERED Influenza Type, Manufacturing Technology, Vaccine Type, End User
    KEY MARKET OPPORTUNITIES Increased vaccine awareness campaigns, Expanded distribution channels, Development of combination vaccines, Rising demand for pediatric vaccines, Growth in telehealth vaccination services
    KEY MARKET DYNAMICS Rising influenza prevalence, Increasing public awareness, Government vaccination initiatives, Advancements in vaccine technology, Seasonal demand fluctuations
    COUNTRIES COVERED US

    FAQs

    What is the expected market size of the US Influenza Vaccination Market in 2024?

    The US Influenza Vaccination Market is expected to be valued at 2.1 billion USD in 2024.

    What will be the market size of the US Influenza Vaccination Market in 2035?

    By 2035, the US Influenza Vaccination Market is projected to reach a valuation of 4.5 billion USD.

    What is the anticipated CAGR for the US Influenza Vaccination Market from 2025 to 2035?

    The expected CAGR for the US Influenza Vaccination Market is 7.174% from 2025 to 2035.

    Which influenza type holds the largest market share in 2024?

    Seasonal influenza is expected to dominate the market, valued at 1.3 billion USD in 2024.

    What is the projected market size for zoonotic influenza by 2035?

    The market for zoonotic influenza is anticipated to grow to 1.7 billion USD by 2035.

    Who are the key players in the US Influenza Vaccination Market?

    Major players include Seqirus, Novartis, Merck, and GlaxoSmithKline among others.

    What opportunities are present in the US Influenza Vaccination Market?

    There are emerging trends in vaccine development and increased awareness creating growth opportunities.

    How is the US Influenza Vaccination Market expected to grow regionally?

    The market is expected to witness significant growth across multiple regions, driven by advancing healthcare infrastructure.

    What challenges does the US Influenza Vaccination Market face?

    Challenges include vaccine hesitancy and the need for continuous research and development.

    What are the key applications driving the US Influenza Vaccination Market?

    Key applications include seasonal immunization programs and public health initiatives targeting at-risk populations.

    US Influenza Vaccination Market Research Report - Forecast to 2035 Infographic
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